Gene

KWMTBOMO16201

Pre Gene Modal

BGIBMGA013920

Annotation

PREDICTED:_UPF0769_protein_C21orf59_homolog_[Amyelois_transitella]

Location

Bomo_Chr28(-):1526013-1527916      View in EpiBrowser

Full name

Cilia- and flagella-associated protein 298-A       + More
Cilia- and flagella-associated protein 298      

Alternative Name

Protein kurly-A
Protein kurly homolog

Location in the cell

Cytoplasmic   Reliability : 3.703

CDS

ATGGTACTATTCCACGTAAAAAGAGGAGATGAAAGTCAATTCCTCTATCAGACAGAGGTGGAAAAGCCCGTTAATGATGTGGTAAAAGACATTGTGGCGATTTTCAATGGAAGGCTGAAGGTTACCAGAATATGTCATGAAATGGAAGAGTTAGCAGATCACGGAACTTTCCTTCCTTTGGAGATGCAGGGACTAACCGAAGAACAGATAAAAGAACTTAAACTGGAGGATCCGTGGGCAAATCGTTGCGCTCCTCAAGGATACGTGGTTGCCAAAGACGAAATGGGTCGCCGTTGTGGTCTCGCCCCTCCAACGAACCTTAAGGAAGTTCTCAAGAAAGCTGCTGAAACTGCGAAGGACATTATCAGTAAGAAGCATGTGGATCTACAGAAGTGCATGACCCAAAAAGACGTAGCAAGGGCCCTGGATGAGCTACGAGGAGCAACGAAAATAGTCTTCCCAGCTGGACTTCCTCCACATGACCCGGTACGCATGGAACTGGATAACGTTGAAGATTTATCCGGGACTCAGGCTGCAAACGAAGTTATCGATCCTTCAAGAGCTTGTTTGTGGGCTTGTGGCAAGAAATTTATCAGCGGAAATAAGCTGAGTGATCATTTAGACAAAATTGCCTTTGCTGGTAAACGGTTTTATTGGACTTAA

Protein

MVLFHVKRGDESQFLYQTEVEKPVNDVVKDIVAIFNGRLKVTRICHEMEELADHGTFLPLEMQGLTEEQIKELKLEDPWANRCAPQGYVVAKDEMGRRCGLAPPTNLKEVLKKAAETAKDIISKKHVDLQKCMTQKDVARALDELRGATKIVFPAGLPPHDPVRMELDNVEDLSGTQAANEVIDPSRACLWACGKKFISGNKLSDHLDKIAFAGKRFYWT

Description

Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:26904945). Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (PubMed:26904945). May suppress canonical Wnt signaling activity (PubMed:26904945).
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly. Seems to be important for initiation rather than maintenance of cilium motility. Required for correct positioning of cilia at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway. May suppress canonical Wnt signaling activity.

Subunit

Interacts with ZMYND10.

Similarity

Belongs to the CFAP298 family.

Keywords

Cell projection   Cilium   Complete proteome   Cytoplasm   Cytoskeleton   Reference proteome  

Feature

chain  Cilia- and flagella-associated protein 298-A

Uniprot

H9JWK6   A0A212F2B0   A0A194QVA6   A0A194PZ72   A0A2W1BIZ3   A0A2A4JZ42   + More
A0A2A4K024   A0A2H1WHG9   A0A3S2L8B7   E2BUU8   C3ZM30   A0A3L8DWW6   A0A026WNP3   H3A7J5   A0A154PBA0   R7TPC8   A0A1S3G4N8   E2A574   G3W6P0   F6V188   A0A0A1WXS3   C1C509   Q4SFY4   G3QBE2   A0A2G9RW42   A0A3B3WTR4   A0A250YEM4   A0A1I8NE53   A0A0F8B119   A0A1B6MUW1   V9L3S5   D2A0M3   A0A3B3WTP8   V4BL47   A0A1B0ABN0   A0A3B5R3X6   A0A195F1J9   A0A0S7HWB2   K9IX50   M4AT18   A0A1U7SBL0   F4X3Y0   A0A2I4AT71   B4N3G8   A0A2K6SE25   A0A0L7QRB7   A0A1L8HCK2   A0A3Q1CD68   A0A3P8U2Y8   A0A1A9VCB9   A0A3Q0RN43   K7G4L8   A0A2J7QUK7   C1BJQ8   A0A2J8UL00   A0A1B0GAY8   A0A093GV08   A0A315VHY8   F6YKK0   A0A2I3H459   A0A1I8PG21   A0A3B3UMN0   A0A2I3LGZ8   Q8BL95   A0A098M1H1   A0A0B6ZQ76   A0A151MEF1   A0A3B5LX73   A0A3Q2EFX1   A0A034VN88   A0A3B5A597   F6ZWN6   A0A2K5Y263   A0A3B3VTA4   I3MQD6   A0A3Q1EDZ9   D3DSE6   A0A1A7XY63   A0A2K5DBV2   A0A087YGD7   A9CAY9   A0A2K5QT11   A0A286ZKE9   F6T2D8   A0A3B5ANN7   A0A3Q3MAQ7   A0A2J8M759   A0A3Q2ZPE2   A0A2K5Y2A5   A0A1A9XXX8   M7B058   A0A340WIW4   A0A0A9YT76   A0A2K6SE13   A0A3B4YHR7   A0A3P9P9Q1   A0A1B0AMD0   A0A2J8UKW7   A0A384A8T1   A0A2K5W4Y8  

Pubmed

19121390    22118469    26354079    28756777    20798317    18563158    + More
30249741    24508170    9215903    23254933    21709235    17495919    25830018    15496914    28087693    25315136    25835551    24402279    18362917    19820115    23542700    21719571    17994087    27762356    26904945    17381049    29703783    16141072    19468303    15489334    21183079    22293439    25348373    20431018    10830953    11181995    17431167    23624526    25401762    26823975   

EMBL

BABH01018447    AGBW02010774    OWR47866.1    KQ461103    KPJ09468.1    KQ459583    + More
KPI98621.1    KZ150092    PZC73675.1    NWSH01000341    PCG77277.1    PCG77278.1    ODYU01008603    SOQ52332.1    RSAL01000091    RVE47993.1    GL450757    EFN80534.1    GG666644    EEN46286.1    QOIP01000003    RLU24429.1    KK107139    EZA57667.1    AFYH01049444    AFYH01049445    AFYH01049446    AFYH01049447    AFYH01049448    KQ434849    KZC08508.1    AMQN01002408    KB309137    ELT95417.1    GL436875    EFN71417.1    AEFK01104528    AEFK01104529    GBXI01010836    JAD03456.1    BT081938    ACO52069.1    CAAE01014601    CAG00448.1    KV932117    PIO32136.1    GFFW01002713    JAV42075.1    KQ042000    KKF19721.1    GEBQ01000251    JAT39726.1    JW873634    AFP06151.1    KQ971338    EFA01664.2    KB202619    ESO89324.1    KQ981856    KYN34450.1    GBYX01437838    JAO43514.1    GABZ01007269    JAA46256.1    GL888624    EGI58927.1    CH964095    EDW79173.1    KQ414782    KOC61173.1    CM004468    BC077554    AAH77554.1    AGCU01106304    AGCU01106305    AGCU01106306    AGCU01106307    NEVH01010537    PNF32265.1    BT074837    ACO09261.1    NDHI03003455    PNJ45910.1    CCAG010004349    KL217075    KFV73211.1    NHOQ01001678    PWA23080.1    ADFV01018959    ADFV01018960    AHZZ02021552    AK045905    AC134560    CH466602    BC019533    GBSI01000389    JAC96106.1    HACG01023020    CEK69885.1    AKHW03006231    KYO22770.1    GAKP01015008    JAC43944.1    AAMC01081352    AAMC01081353    AGTP01030449    AGTP01030450    AP000275    KF457218    CH471079    EAX09867.1    HADW01006428    HADX01000850    SBP23082.1    AYCK01000565    DP000484    ABW97185.1    AEMK02000092    JSUE03027204    NBAG03000265    PNI55349.1    KB589771    EMP25443.1    GBHO01007382    GBRD01007395    GDHC01013517    JAG36222.1    JAG58426.1    JAQ05112.1    JXJN01000389    PNJ45912.1    AQIA01044582   

Proteomes

UP000005204    UP000007151    UP000053240    UP000053268    UP000218220    UP000283053    + More
UP000008237    UP000001554    UP000279307    UP000053097    UP000008672    UP000076502    UP000014760    UP000081671    UP000000311    UP000007648    UP000002280    UP000007303    UP000007635    UP000261480    UP000095301    UP000007266    UP000030746    UP000092445    UP000002852    UP000078541    UP000189705    UP000007755    UP000192220    UP000007798    UP000233220    UP000053825    UP000186698    UP000257160    UP000265080    UP000078200    UP000261340    UP000007267    UP000235965    UP000092444    UP000053875    UP000008225    UP000001073    UP000095300    UP000261500    UP000028761    UP000000589    UP000050525    UP000261380    UP000265020    UP000261400    UP000008143    UP000233140    UP000005215    UP000257200    UP000005640    UP000233020    UP000028760    UP000233040    UP000008227    UP000006718    UP000261640    UP000264800    UP000092443    UP000031443    UP000265300    UP000261360    UP000242638    UP000092460    UP000261681    UP000233100   

PRIDE

H9JWK6    Q8BL95    D3DSE6   

Pfam

PF11069   DUF2870

Interpro

IPR021298   CFAP298       

ProteinModelPortal

H9JWK6   A0A212F2B0   A0A194QVA6   A0A194PZ72   A0A2W1BIZ3   A0A2A4JZ42   + More
A0A2A4K024   A0A2H1WHG9   A0A3S2L8B7   E2BUU8   C3ZM30   A0A3L8DWW6   A0A026WNP3   H3A7J5   A0A154PBA0   R7TPC8   A0A1S3G4N8   E2A574   G3W6P0   F6V188   A0A0A1WXS3   C1C509   Q4SFY4   G3QBE2   A0A2G9RW42   A0A3B3WTR4   A0A250YEM4   A0A1I8NE53   A0A0F8B119   A0A1B6MUW1   V9L3S5   D2A0M3   A0A3B3WTP8   V4BL47   A0A1B0ABN0   A0A3B5R3X6   A0A195F1J9   A0A0S7HWB2   K9IX50   M4AT18   A0A1U7SBL0   F4X3Y0   A0A2I4AT71   B4N3G8   A0A2K6SE25   A0A0L7QRB7   A0A1L8HCK2   A0A3Q1CD68   A0A3P8U2Y8   A0A1A9VCB9   A0A3Q0RN43   K7G4L8   A0A2J7QUK7   C1BJQ8   A0A2J8UL00   A0A1B0GAY8   A0A093GV08   A0A315VHY8   F6YKK0   A0A2I3H459   A0A1I8PG21   A0A3B3UMN0   A0A2I3LGZ8   Q8BL95   A0A098M1H1   A0A0B6ZQ76   A0A151MEF1   A0A3B5LX73   A0A3Q2EFX1   A0A034VN88   A0A3B5A597   F6ZWN6   A0A2K5Y263   A0A3B3VTA4   I3MQD6   A0A3Q1EDZ9   D3DSE6   A0A1A7XY63   A0A2K5DBV2   A0A087YGD7   A9CAY9   A0A2K5QT11   A0A286ZKE9   F6T2D8   A0A3B5ANN7   A0A3Q3MAQ7   A0A2J8M759   A0A3Q2ZPE2   A0A2K5Y2A5   A0A1A9XXX8   M7B058   A0A340WIW4   A0A0A9YT76   A0A2K6SE13   A0A3B4YHR7   A0A3P9P9Q1   A0A1B0AMD0   A0A2J8UKW7   A0A384A8T1   A0A2K5W4Y8  

KEGG

101744391    no KO assigned | (RefSeq) UPF0769 protein C21orf59

GO

GO:0003352   GO:0005856   GO:0005929   GO:0005737   GO:0060271   GO:0005829   GO:0031514  

PANTHER

PTHR13238  

Subcellular location

Cytoplasm   Appears in cytoplasmic puncta, compatible with a centrosomal localization (By similarity).   With evidence from 1 publications.
Cytoskeleton   Appears in cytoplasmic puncta, compatible with a centrosomal localization (By similarity).   With evidence from 1 publications.
Cilium basal body   Appears in cytoplasmic puncta, compatible with a centrosomal localization (By similarity).   With evidence from 1 publications.

Length:

220

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.06505

outside

1  -  220

 

 

Pi

43.208365

Theta

166.900032

Tajima's D

-0.885388

CLR

110.360446

CSRT

0.15969201539923

Interpretation

Uncertain