Gene

KWMTBOMO16200

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr28(-):1521667-1524696      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.868

CDS

ATGGTTAGGAATGACAGACTCACCGCCTCGAAAGGCGGGACTGCCATTTACTATAGGCGGGCCCTGCACGTTGTCCCTCTCGATACTCCCTCGCTCTTACATATCGAGGCGTCAGTGTGTCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTCCTGAGCAGTGACATCGAGTCACTGTTCGGCATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGTACAAACGTTAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTCACCTTTGAAATAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCATTGCTTAGGAACGTAACTCTGCGCTTGCGTTCCATCGAAGCACTGTCAGAGCCCGACTCAGACCACCGACCTGTCCTTATGCAGCTCGGTCGCCCTCACAACCCAGCCACTGTTACGAGGACCATGGTGGATTGGAATAAGCTGGGCACGTGCCTAGCCGACGCCGTTCCGCCAATCCTCCCTTACGGCCCGGATTCGAATCCATCCCCCGAGGACACCGTCGAATCCATAAACATCATTACCGATCACATCTCTTCCGCGATCATTAGATCTTCTAAAGAAGTCGATGTGGAGGACAGCTTCCACCGCATCAGACTGTCCCCCGATCTTAGGAATCTCTTAAGAGTTAGGAACGCGGCAATCCGGGCCTACGATCGACTTCCCACGCATTCAAACCGGATTCAGATGCGTCGTCTACAACGCGAAGTCCACTCCCGCTTAAGCGACGCGCGTAACGATAATTGGCATAGTTATTTAGAACAACTCGCGCCCTCCCACCAAGCATACTGGCGACTAGCTAGGACTCTCAAATCCGAAACTACCGCTACTATGCCTCCCCTCTTACGCCCTTCAGGCCAACCACCGGCATTCGATGACGATGACAAGGCTGAGCTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACTGACGAAGTTAGAGACGCGATCCACAACCTCCAACCTAGGAAGGCACCAGGCTCCGACGGCATCCACAACCGCGCGCTAAAATTTTTGCCAGTCCAACTGATAGCAATGTTGGCTACAATTTTAAATGCCGCTATGACGCACTGCATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGTATACATAAGCCGGGCAAACCGAGAAACGTAACTTCTAGTTACCGTCCGATTAGTCTCCTCTCGACGATAGGAAAAATTTACGAACGTCTCCTTAGGAAACGCCTCTGGGATTTTGTTACCGCAAACAAAATTCTCATAGACGAACAGTTCGGATTCCGCTCAAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATTCTGATAGGACTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGACATCGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTGATCTACAAACTGTACAACATGGGAATGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCAACTGACTGCCGGAGTCCCGCAAGGCTCCGCGCTCTCCCCGTTATTATTTAGTTTGTATATCAATGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGACGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGCTGCTTCATCGGCGACTCCAGATCGCAGTAGCCACCATGGGACAGTGGTTCCGGAAGTGGCGAATAGACATCAACCCCACGAAAAGCGCAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAATATCACTTCGAGCATCCCACTCCGTAGTAGGCGCGCAAACACCTCCGCCGTTAGTCCCATCACTCTCTTTGGCCAGCCCATACCGTGGGTCTCGAAGGTCAAATATCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGTCCCCATATAAAAACGGTACGCGACCGCGCCGCGTTTATTCTAGGACGACTCTATCCAATGCTTTGTAGTCGAAGTAAACTGTCCCTCCGCAATAAGGTAACTCTCTACAAAACTTGTATACGCCCCGTCATGACGTATGCAAGCGTAGTGTTCGCTCACTCAGCCCGCACCCACTTGAAATCCCTTCAGGTTATTCAATCACGATTCTGCAGGATAGCCGTCGGAGCGCCATGGTTCCTTAGGAATGTGGATCTCCACGATGACCTGGAGCTCGACTCTCTTAGTAAGTATCTACAGTCGGCATCACTGCGCCATTTTGAGAAGGCGGCACGACATGAGAACCCTCTCATCGTAGCCGCTGGAAATTACATATCCGACCCAGTAGACCGAATGGTAAACCGTCGACGTCGCCCAAAGCACGTCATTACGGATCCTCCTGATCCATTAACGGTGCTTTTAGGCACCACAAGCACCGGTCACCGTCCTCGTCGAACCCGTCGCTTGCGACGAAGGGCTCGACGAGCGAACTAA

Protein

MVRNDRLTASKGGTAIYYRRALHVVPLDTPSLLHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEIVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEALSEPDSDHRPVLMQLGRPHNPATVTRTMVDWNKLGTCLADAVPPILPYGPDSNPSPEDTVESINIITDHISSAIIRSSKEVDVEDSFHRIRLSPDLRNLLRVRNAAIRAYDRLPTHSNRIQMRRLQREVHSRLSDARNDNWHSYLEQLAPSHQAYWRLARTLKSETTATMPPLLRPSGQPPAFDDDDKAELLADALQEQCTTSTQHADPEHTELVDREVERRASLPPSDALPPITTDEVRDAIHNLQPRKAPGSDGIHNRALKFLPVQLIAMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPRNVTSSYRPISLLSTIGKIYERLLRKRLWDFVTANKILIDEQFGFRSKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDIAKAFDKVWHNGLIYKLYNMGMPDRLVLIIRDFLSNRSFRYRVEGTRSRPRQLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQIAVATMGQWFRKWRIDINPTKSAAVLFKRGRPPNITSSIPLRSRRANTSAVSPITLFGQPIPWVSKVKYLGVTLDRGMTFRPHIKTVRDRAAFILGRLYPMLCSRSKLSLRNKVTLYKTCIRPVMTYASVVFAHSARTHLKSLQVIQSRFCRIAVGAPWFLRNVDLHDDLELDSLSKYLQSASLRHFEKAARHENPLIVAAGNYISDPVDRMVNRRRRPKHVITDPPDPLTVLLGTTSTGHRPRRTRRLRRRARRAN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   A0A2S2PPK8   X1WLB2   Q07995   J9LC21   A0A2S2Q383   D7EM17   A0A224XF24   A0A3N5Z7I3   J9M522   X1WNI2   A0A2S2QEE0   A0A2M4BDA5   A0A2J7QR37   A0A2M4BD66   A0A2M4CV52   A0A2M4CV42   A0A2M4BD62   A0A224X6Q4   A0A2J7QY69   A0A2J7PBY3   A0A2J7PU96   A0A2M4BEF4   A0A2M4BEZ9   X1WZH0   A0A2S2NGV8   J9KKL3   K7IN67   A0A087UGF5   A0A2M4BD67   A0A224XB44   A0A2J7R7D0   A0A2J7Q6J2   A0A2M4BDV6   J9LFC9   A0A2S2N814   A0A069DZL8   X1WQI9   A0A224X6T4   A0A224X6S1   J9JS95   A0A2J7PQB5   A0A2J7PDM0   A0A1Y1LKN6   V9GZF1   A0A087UCW3   A0A224X746   P21329   A0A0L0CBP5   A0A2J7PVX3   A0A0A9YJ00   A0A2S2P698   A0A2H8TF37   D7GYA5   A0A224XI99   A0A0A9YU04   A0A2J7PP17   A0A2S2R9D4   A0A2J7RE85   A0A224X6R6   A0A224X6U5   A0A2S2PJG2   A0A1Y1KFR3   Q8T9X4   P21328   Q8I7P8   A0A2J7QB68   A0A2S2PA10   J9KLB1   A0A2S2NH02   A0A069DX78   A0A224XJI0   A0A0A9YSX4   A0A224XHW8   A0A1B6EGD8   A0A0V0G5B6   A0A2A4IUM2   A0A2S2Q352   A0A0J7MYU2   J9KPF1   Q24335   A0A2S2P6C4  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    8387152    30086797    20075255    26334808    1327974    1701254    26108605    25401762    2463954    3040362    1714378    2441397   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GBBI01004571    JAC14141.1    GGMR01018716    MBY31335.1    ABLF02042518    ABLF02057746    S59870    AAB26437.2    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GGMS01002992    MBY72195.1    KQ973412    EFA12510.2    GFTR01008038    JAW08388.1    RPOV01000134    RPJ78669.1    ABLF02024246    ABLF02008153    ABLF02008462    ABLF02008464    GGMS01006359    MBY75562.1    GGFJ01001842    MBW50983.1    NEVH01011985    PNF31054.1    GGFJ01001844    MBW50985.1    GGFL01004957    MBW69135.1    GGFL01005012    MBW69190.1    GGFJ01001843    MBW50984.1    GFTR01008279    JAW08147.1    NEVH01009134    PNF33528.1    NEVH01027074    PNF13841.1    NEVH01021205    PNF19912.1    GGFJ01002256    MBW51397.1    GGFJ01002257    MBW51398.1    ABLF02034467    GGMR01003407    MBY16026.1    ABLF02029306    ABLF02029314    ABLF02060138    KK119692    KFM76444.1    GGFJ01001858    MBW50999.1    GFTR01008262    JAW08164.1    NEVH01006736    PNF36716.1    NEVH01017470    PNF24199.1    GGFJ01001857    MBW50998.1    ABLF02023911    GGMR01000676    MBY13295.1    GBGD01000415    JAC88474.1    ABLF02022418    GFTR01008261    JAW08165.1    GFTR01008271    JAW08155.1    ABLF02028535    ABLF02028545    NEVH01022639    PNF18527.1    NEVH01026386    PNF14434.1    GEZM01053022    JAV74219.1    M95171    AAA29354.1    KK119261    KFM75202.1    GFTR01008151    JAW08275.1    M38437    JRES01000644    KNC29657.1    NEVH01020940    PNF20481.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GGMR01012305    MBY24924.1    GFXV01000908    MBW12713.1    KQ973363    EFA13335.2    GFTR01008256    JAW08170.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    NEVH01023280    PNF18085.1    GGMS01017365    MBY86568.1    NEVH01005277    PNF39135.1    GFTR01008269    JAW08157.1    GFTR01008251    JAW08175.1    GGMR01016905    MBY29524.1    GEZM01084969    JAV60363.1    AF456125    AAL57609.1    M22874    M38643    AY180919    AAN87272.1    NEVH01016302    PNF25823.1    GGMR01013409    MBY26028.1    ABLF02040174    ABLF02040183    ABLF02055266    GGMR01003864    MBY16483.1    GBGD01000389    JAC88500.1    GFTR01008257    JAW08169.1    GBHO01008295    JAG35309.1    GFTR01008254    JAW08172.1    GEDC01000337    JAS36961.1    GECL01003538    JAP02586.1    NWSH01007753    PCG62823.1    GGMS01002955    MBY72158.1    LBMM01013518    KMQ85605.1    ABLF02041767    M17214    AAA28508.1    GGMR01012283    MBY24902.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000002358    UP000054359    + More
UP000037069    UP000218220    UP000036403   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    P21329    Q8T9X4    P21328    + More
Q8I7P8    Q24335   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   A0A2S2PPK8   X1WLB2   Q07995   J9LC21   A0A2S2Q383   D7EM17   A0A224XF24   A0A3N5Z7I3   J9M522   X1WNI2   A0A2S2QEE0   A0A2M4BDA5   A0A2J7QR37   A0A2M4BD66   A0A2M4CV52   A0A2M4CV42   A0A2M4BD62   A0A224X6Q4   A0A2J7QY69   A0A2J7PBY3   A0A2J7PU96   A0A2M4BEF4   A0A2M4BEZ9   X1WZH0   A0A2S2NGV8   J9KKL3   K7IN67   A0A087UGF5   A0A2M4BD67   A0A224XB44   A0A2J7R7D0   A0A2J7Q6J2   A0A2M4BDV6   J9LFC9   A0A2S2N814   A0A069DZL8   X1WQI9   A0A224X6T4   A0A224X6S1   J9JS95   A0A2J7PQB5   A0A2J7PDM0   A0A1Y1LKN6   V9GZF1   A0A087UCW3   A0A224X746   P21329   A0A0L0CBP5   A0A2J7PVX3   A0A0A9YJ00   A0A2S2P698   A0A2H8TF37   D7GYA5   A0A224XI99   A0A0A9YU04   A0A2J7PP17   A0A2S2R9D4   A0A2J7RE85   A0A224X6R6   A0A224X6U5   A0A2S2PJG2   A0A1Y1KFR3   Q8T9X4   P21328   Q8I7P8   A0A2J7QB68   A0A2S2PA10   J9KLB1   A0A2S2NH02   A0A069DX78   A0A224XJI0   A0A0A9YSX4   A0A224XHW8   A0A1B6EGD8   A0A0V0G5B6   A0A2A4IUM2   A0A2S2Q352   A0A0J7MYU2   J9KPF1   Q24335   A0A2S2P6C4  

PDB

6AR3     E-value=0.000919859,     Score=104

KEGG

105842032    no KO assigned | (RefSeq) uncharacterized LOC105842032

GO

GO:0003964   GO:0004519  

Length:

899

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.798059999999999

Exp number, first 60 AAs:

0.02145

Total prob of N-in:

0.01360

outside

1  -  899

 

 

Pi

30.521395

Theta

15.490192

Tajima's D

0.068409

CLR

0.30229

CSRT

0.393030348482576

Interpretation

Uncertain