Gene

KWMTBOMO16196  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013964

Annotation

vacuolar_ATPase_subunit_C_[Bombyx_mori]

Location

Bomo_Chr28(+):1122957-1143833      View in EpiBrowser

Full name

V-type proton ATPase subunit C      

Alternative Name

Vacuolar proton pump subunit C

Location in the cell

Cytoplasmic   Reliability : 1.992

CDS

ATGACTGAATACTGGGTGATCAGTGCCCCTGGCGACAAGACCTGTCAGCAGACTTGGGATACCCTGAACAATGCCACCAAATCAGGCAACCTCAGTGTCAACTATAAATTCCCTATTCCTGACCTTAAGGTGGGAACTTTGGATCAGTTGGTGGGGCTGTCAGATGATCTGGGCAAGCTTGACACTTTCGTCGAAGGTGTGACCAGGAAGGTAGCCCAGTACCTTGGAGAGGTACTTGAAGATCAGCGCGATAAGCTCCATGAAAACTTGATGGCCAATAACAGTGACCTCCCCACTTATTTGACTCGCTTCCAATGGGACATGGCTAAGTACCCCATAAAGCAGAGTCTGCGGAATATCGCCGACATCATAAGCAAACAGGTCGGACAGATCGACGCGGATCTGAAGGTCAAGTCCTCCGCCTACAACGCTCTCAAAGGAAACCTACACAATTTAGAGAAGAAACAGACCGGGAGCTTGTTGACCCGCAACTTGGCCGATCTAGTCAAGAAGGAGCACTTCATCTTGGACAGCGAGTACCTGACCACACTCCTGGTCATCGTGCCCAAGTCAATGTTCAACGACTGGAATGCCAACTACGAGAAGATAACGGACATGATCGTGCCGCGCTCCACCCAGCTCGTCCACCAGGACAACGACTACGGACTCTTCACCGTCACCCTCTTCAAGAAGGTTGCGGACGAGTTCAAGCTGCACGCTCGCGAGCGCAAGTTCGTCGTGCGCGAGTTCGCTTACAACGAGGCCGACCTGCTCGCCGGCAAGAACGAGATCACCAAGCTCGTCACCGACAAGAAGAAGCAGTTTGGACCGCTGGTGCGATGGTTGAAGGTGAACTTCTCCGAGTGCTTCTGCGCTTGGATCCACGTTAAAGCTCTGCGTGTGTTCGTCGAATCCGTTTTGAGATACGGTCTGCCGGTGAACTTCCAGGCCGTGGTGATGGTCCCGGCGCGCAAGAGCATGAAGAAGCTGCGCGACCTCCTCAACCAGCTCTACGCGCACCTCGACCACTCCGCGCACGCGCACTCCGCCGCCGCGCCGGACAGCGTGGAACTAGCCGGCCTAGGTTTCGGTCAATCGGAATATTTCCCGTATGTTTTCTATAAGATCAACATCGACATGATCGAGAAATCGTCGGCCTAA

Protein

MTEYWVISAPGDKTCQQTWDTLNNATKSGNLSVNYKFPIPDLKVGTLDQLVGLSDDLGKLDTFVEGVTRKVAQYLGEVLEDQRDKLHENLMANNSDLPTYLTRFQWDMAKYPIKQSLRNIADIISKQVGQIDADLKVKSSAYNALKGNLHNLEKKQTGSLLTRNLADLVKKEHFILDSEYLTTLLVIVPKSMFNDWNANYEKITDMIVPRSTQLVHQDNDYGLFTVTLFKKVADEFKLHARERKFVVREFAYNEADLLAGKNEITKLVTDKKKQFGPLVRWLKVNFSECFCAWIHVKALRVFVESVLRYGLPVNFQAVVMVPARKSMKKLRDLLNQLYAHLDHSAHAHSAAAPDSVELAGLGFGQSEYFPYVFYKINIDMIEKSSA

Description

Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity).

Subunit

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.
V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).

Similarity

Belongs to the V-ATPase C subunit family.

Keywords

Hydrogen ion transport   Ion transport   Transport   Alternative splicing   Complete proteome   Reference proteome  

Feature

chain  V-type proton ATPase subunit C
splice variant  In isoform A.

Uniprot

Q2F673   I4DR85   S4PV58   A0A076PXI2   Q9U5N1   A0A2W1B9M2   + More
A0A2R8G1V8   D6WTD4   A0A2A4J9R2   A0A2P8XH01   A0A2J7RHD8   A0A1B6EYU4   A4KYS3   A0A232EJE5   A0A067QZJ7   A0A0C9RWM2   A0A026WRR5   A0A1L8DF84   F4X7W1   V5I8V6   E2BTC0   B4P685   Q9V7N5-2   A0A1Y1MCX9   B4HSW7   B4QHX5   A0A0Q9WA32   A0A1Q3FY65   J9K1C1   A0A1I9WLJ0   A0A0Q9VXY6   U4U920   A0A1J1HYK5   A0A2Z4EF26   A0A2S2NGE2   A0A1L8ECS3   A0A1W4UXN1   A0A3B0JDV2   B4GAC0   A0A182H7D6   B3MFN3   A0A1W4WC36   A0A034WRR8   V9IAU4   T1DI77   U5EWK4   A0A1L8EHF0   W8BXQ6   A0A1L8EH24   A0A1B6CKL6   A0A0A1WNQ5   A0A182WLA5   A0A182M2Q2   A0A182RZ07   T1PP69   A0A1I8QEB7   E1ZUV1   A0A0K8TRG7   A0A084WE88   A0A182UXR0   A0A182TV74   A0A182XMD6   A0A182KPZ6   Q7Q6H4   A0A182I270   A0A182YJ84   A0A0V0GCQ3   A0A182JMH7   A0A182P2V7   A0A2M4BR66   A0A069DTM9   A0A0P4VUX5   A0A2M4A4V6   A0A2M4CTD0   A0A336M2X5   A0A336LZ40   A0A2M3Z182   T1DH19   A0A1S4ELA8   D3TMG7   A0A1A9XWH0   A0A0A9W801   A0A2J7RHE6   A0A1A9VU46   A0A0K8SJZ5   A0A0K8SE36   A0A146MHI9   A0A0A9YAE1   Q1HQL5   A0A1L8EAD2   A0A224XSB6   A0A0P5VRC2   E9FQR8   A0A0N8BEA6   A0A164PT35   A0A0P6I9H9   A0A0P5XTA3   A0A0P5J7Y9   A0A0P6BBZ7   H9JWQ0  

Pubmed

22651552    23622113    11030595    28756777    18362917    19820115    + More
29403074    28648823    24845553    24508170    30249741    21719571    20798317    17994087    17550304    9584098    10731132    12537572    12537569    28004739    22936249    27538518    23537049    26483478    25348373    24330624    24495485    25830018    25315136    26369729    24438588    20966253    12364791    14747013    17210077    25244985    26334808    27129103    20353571    25401762    26823975    17204158    21292972    19121390   

EMBL

DQ311199    ABD36144.1    AK404992    BAM20425.1    GAIX01009113    JAA83447.1    + More
KJ854407    AIJ50380.1    AJ249388    KZ150244    PZC71888.1    KY921846    AVP73918.1    KQ971352    EFA06700.2    NWSH01002385    PCG68418.1    PYGN01002161    PSN31288.1    NEVH01003743    PNF40255.1    GECZ01026617    JAS43152.1    EF156436    ABO61291.1    NNAY01004023    OXU18483.1    KK853153    KDR10550.1    GBYB01013434    GBYB01013435    JAG83201.1    JAG83202.1    KK107128    QOIP01000006    EZA58381.1    RLU21282.1    GFDF01008978    JAV05106.1    GL888900    EGI57447.1    GALX01004020    JAB64446.1    GL450389    EFN81041.1    CM000158    EDW91935.2    AF006655    AE013599    AY061038    AY102676    BT015974    GEZM01039785    JAV81197.1    CH480816    EDW48131.1    CM000362    CM002911    EDX07346.1    KMY94245.1    CH940667    KRF77675.1    GFDL01002544    JAV32501.1    ABLF02008149    KU932374    APA34010.1    KRF77676.1    KB631912    ERL87116.1    CVRI01000020    CRK91209.1    MF537670    AWV49185.1    GGMR01003383    MBY16002.1    GFDG01002278    JAV16521.1    OUUW01000001    SPP73430.1    CH479181    EDW31872.1    JXUM01028212    JXUM01028213    JXUM01028214    KQ560814    KXJ80786.1    CH902619    EDV37723.1    GAKP01002489    JAC56463.1    JR037434    JR037435    AEY57767.1    AEY57768.1    GALA01001091    JAA93761.1    GANO01001376    JAB58495.1    GFDG01000776    JAV18023.1    GAMC01012551    JAB94004.1    GFDG01000777    JAV18022.1    GEDC01024175    GEDC01023370    JAS13123.1    JAS13928.1    GBXI01017216    GBXI01014239    JAC97075.1    JAD00053.1    AXCM01007399    KA645139    KA649793    AFP64422.1    GL434297    EFN75043.1    GDAI01000875    JAI16728.1    ATLV01023195    KE525341    KFB48532.1    AAAB01008960    EAA11948.4    APCN01000126    GECL01000596    JAP05528.1    GGFJ01006332    MBW55473.1    GBGD01001768    JAC87121.1    GDKW01000757    JAI55838.1    GGFK01002431    MBW35752.1    GGFL01004426    MBW68604.1    UFQT01000465    SSX24592.1    UFQT01000243    SSX22281.1    GGFM01001523    MBW22274.1    GAMD01002541    JAA99049.1    EZ422619    ADD18895.1    GBHO01040058    GBRD01013622    GDHC01018586    JAG03546.1    JAG52204.1    JAQ00043.1    PNF40254.1    GBRD01012241    JAG53583.1    GBRD01014281    GBRD01014280    JAG51546.1    GDHC01000202    JAQ18427.1    GBHO01017094    GDHC01015317    GDHC01006382    JAG26510.1    JAQ03312.1    JAQ12247.1    DQ440429    ABF18462.1    GFDG01003108    JAV15691.1    GFTR01005545    JAW10881.1    GDIP01110948    JAL92766.1    GL732523    EFX90034.1    GDIQ01186211    JAK65514.1    LRGB01002568    KZS07115.1    GDIQ01024374    JAN70363.1    GDIP01067562    JAM36153.1    GDIQ01203359    JAK48366.1    GDIP01031396    JAM72319.1    BABH01018421   

Proteomes

UP000007266    UP000218220    UP000245037    UP000235965    UP000215335    UP000027135    + More
UP000053097    UP000279307    UP000007755    UP000008237    UP000002282    UP000000803    UP000001292    UP000000304    UP000008792    UP000007819    UP000030742    UP000183832    UP000192221    UP000268350    UP000008744    UP000069940    UP000249989    UP000007801    UP000192223    UP000075920    UP000075883    UP000075900    UP000095301    UP000095300    UP000000311    UP000030765    UP000075903    UP000075902    UP000076407    UP000075882    UP000007062    UP000075840    UP000076408    UP000075880    UP000075885    UP000079169    UP000092443    UP000078200    UP000000305    UP000076858    UP000005204   

PRIDE

Q2F673    Q9U5N1    Q9V7N5    H9JWQ0   

Pfam

PF03223   V-ATPase_C

Interpro

IPR004907   ATPase_V1-cplx_csu        + More
IPR036132   Vac_ATP_synth_c_sf       

SUPFAM

SSF118203   SSF118203       

CDD

cd14785  V-ATPase_C

ProteinModelPortal

Q2F673   I4DR85   S4PV58   A0A076PXI2   Q9U5N1   A0A2W1B9M2   + More
A0A2R8G1V8   D6WTD4   A0A2A4J9R2   A0A2P8XH01   A0A2J7RHD8   A0A1B6EYU4   A4KYS3   A0A232EJE5   A0A067QZJ7   A0A0C9RWM2   A0A026WRR5   A0A1L8DF84   F4X7W1   V5I8V6   E2BTC0   B4P685   Q9V7N5-2   A0A1Y1MCX9   B4HSW7   B4QHX5   A0A0Q9WA32   A0A1Q3FY65   J9K1C1   A0A1I9WLJ0   A0A0Q9VXY6   U4U920   A0A1J1HYK5   A0A2Z4EF26   A0A2S2NGE2   A0A1L8ECS3   A0A1W4UXN1   A0A3B0JDV2   B4GAC0   A0A182H7D6   B3MFN3   A0A1W4WC36   A0A034WRR8   V9IAU4   T1DI77   U5EWK4   A0A1L8EHF0   W8BXQ6   A0A1L8EH24   A0A1B6CKL6   A0A0A1WNQ5   A0A182WLA5   A0A182M2Q2   A0A182RZ07   T1PP69   A0A1I8QEB7   E1ZUV1   A0A0K8TRG7   A0A084WE88   A0A182UXR0   A0A182TV74   A0A182XMD6   A0A182KPZ6   Q7Q6H4   A0A182I270   A0A182YJ84   A0A0V0GCQ3   A0A182JMH7   A0A182P2V7   A0A2M4BR66   A0A069DTM9   A0A0P4VUX5   A0A2M4A4V6   A0A2M4CTD0   A0A336M2X5   A0A336LZ40   A0A2M3Z182   T1DH19   A0A1S4ELA8   D3TMG7   A0A1A9XWH0   A0A0A9W801   A0A2J7RHE6   A0A1A9VU46   A0A0K8SJZ5   A0A0K8SE36   A0A146MHI9   A0A0A9YAE1   Q1HQL5   A0A1L8EAD2   A0A224XSB6   A0A0P5VRC2   E9FQR8   A0A0N8BEA6   A0A164PT35   A0A0P6I9H9   A0A0P5XTA3   A0A0P5J7Y9   A0A0P6BBZ7   H9JWQ0  

PDB

6O7X     E-value=5.64121e-58,     Score=568

KEGG

692828    K02148 V-type H+-transporting ATPase subunit C | (RefSeq) vacuolar ATPase subunit C

PATHWAY

00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04145    Phagosome - Bombyx mori (domestic silkworm)
04150    mTOR signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0033180   GO:0015078   GO:0015991   GO:0046961   GO:0000221   GO:0008553   GO:0033181   GO:1902600   GO:0016021   GO:0006412   GO:0016791   GO:0001678   GO:0005536   GO:0046835   GO:0006281   GO:0006259  

PANTHER

PTHR10137  

Length:

386

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06385

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00858

outside

1  -  386

 

 

Pi

164.266289

Theta

165.960707

Tajima's D

0.032545

CLR

12.827073

CSRT

0.379931003449827

Interpretation

Uncertain