Gene

KWMTBOMO16088  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014536

Annotation

heat_shock_protein_70_A1_[Bombyx_mori]

Location

Bomo_Chr27(+):8758785-8761136      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.445

CDS

ATGCCAGCTATCGGAATCGATTTGGGAACGACATACTCATGTGTTGGAGTATGGCAGCACGGGAACGTGGAGATCATCGCGAACGACCAGGGCAACCGCACCACACCATCGTACGTCGCGTTCACGGACACGGAGCGTCTCATCGGCGACGCAGCCAAGAACCAGGTCGCCTTGAACCCTAACAACACCGTGTTCGACGCGAAGAGGCTGATCGGGAGGAAATTCGACGACCCCAAGATTCAGCAGGACATGAAGCACTGGCCCTTCAAAGTGATCAACGACTGCGGCAAACCGAAAATACAGATCGAGTTCAAAGGTGAGACGAAACGATTTGCGCCAGAAGAAATTAGCAGCATGGTGCTGACAAAAATGAAGGAGACGGCGGAAGCCTATCTGGGAAGTACAGTGCGGGATGCGGTAGTCACAGTTCCGGCATACTTCAACGACTCCCAGCGTCAGGCCACCAAGGACGCCGGAGCCATAGCCGGCCTGAACGTGCTTCGCATCATCAACGAGCCCACAGCCGCCGCGCTCGCGTACGGTCTCGACAAGAACCTCAAGGGTGAGAGAAATGTTCTTATCTTCGATCTGGGTGGAGGAACCTTCGACGTGTCCATCCTGACTATCGACGAGGGATCGTTGTTCGAAGTGAAGTCCACAGCCGGCGACACGCACCTGGGAGGCGAAGACTTTGATAACCGACTAGTCAACCATCTTGCGGAAGAGTTCAAGCGCAAGTACAAGAAGGATCTGCGCCTGAACTCTCGCGCACTCCGACGCCTCCGCACGGCCGCTGAGCGCGCCAAGAGGACACTCTCATCCAGCACCGAGGCCACCATCGAGATTGACGCTCTGTATGAGGGCATCGACTTCTACACGCGAGTCTCCCGCGCCCGCTTCGAGGAACTGAACGCGGACCTGTTCAGGGGAACTCTGGAACCCGTCGAGAAGGCACTCAAGGATGCTAAACTCGACAAGAGTCAGATCCACGACGTGGTCCTCGTCGGAGGCTCCACCCGCATTCCGAAAGTACAAACTATGCTCCAAAACTTCTTCTGTGGGAAGAAACTGAACCTATCCATCAATCCGGACGAAGCCGTAGCCTACGGTGCAGCAGTCCAGGCAGCCATCCTGAGCGGCGAGACCGACTCCAAGATACAGGACGTCTTGTTGGTCGACGTGGCTCCTCTGTCCCTCGGTATTGAGACAGCCGGCGGCGTGATGACGAAGATCATCGAACGAAACTCGAAGATTCCGTGCAAACAGTCTCAGACATTCACGACGTATTCAGACAATCAGCCGGCCGTCACCATCCAGGTGTACGAGGGAGAGAGAGCGATGACAAAGGACAACAACCTACTGGGCACGTTCGACCTGACGGGGATCCCGCCCGCGCCGCGAGGAGTGCCCAAGATCGACGTGACGTTCGACATGGACGCTAACGGCATCCTGAACGTGTCGGCCAAGGAGAACAGCACCGGCCGCAGCAAGAACATCGTGATCAAGAACGACAAGGGTCGTCTCTCGCAAGCGGAGATCGATCGCATGCTGTCCGAGGCAGAGCGGTACAAGGAGGAAGACGAGAAGCAGAGACAGCGCGTGGCCGCTCGGAACCAGCTCGAATCGTATTTGTTCAGCGTGAAGCAGGCGCTCGACGAGGCCGGCGACAAACTGAGCGACGCAGACAAGAGCACGGCGCGCGACGCGTGTGACGAGGCGCTGCGGTGGCTGGACAACAACACTCTCGCTGACCAGGATGAATACGAGCACAAGCTGAAGGATGTGCAGCGAGTGTGTTCGCCGGTCATGAGCAAGATGCACGGTGCGGCGCCCGGCGGTATGCCAGGAGGAATGCCGGGCGGTATGCCGGGAGGATACCAACAAGCGAGGAGTGATGGACCCACAGTTGAGGAAGTCGACTAA

Protein

MPAIGIDLGTTYSCVGVWQHGNVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPNNTVFDAKRLIGRKFDDPKIQQDMKHWPFKVINDCGKPKIQIEFKGETKRFAPEEISSMVLTKMKETAEAYLGSTVRDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVKSTAGDTHLGGEDFDNRLVNHLAEEFKRKYKKDLRLNSRALRRLRTAAERAKRTLSSSTEATIEIDALYEGIDFYTRVSRARFEELNADLFRGTLEPVEKALKDAKLDKSQIHDVVLVGGSTRIPKVQTMLQNFFCGKKLNLSINPDEAVAYGAAVQAAILSGETDSKIQDVLLVDVAPLSLGIETAGGVMTKIIERNSKIPCKQSQTFTTYSDNQPAVTIQVYEGERAMTKDNNLLGTFDLTGIPPAPRGVPKIDVTFDMDANGILNVSAKENSTGRSKNIVIKNDKGRLSQAEIDRMLSEAERYKEEDEKQRQRVAARNQLESYLFSVKQALDEAGDKLSDADKSTARDACDEALRWLDNNTLADQDEYEHKLKDVQRVCSPVMSKMHGAAPGGMPGGMPGGMPGGYQQARSDGPTVEEVD

Similarity

Belongs to the heat shock protein 70 family.

Uniprot

F8UN42   A6P319   Q2F683   A0A2C9PHS1   C4P3P9   Q6L6T3   + More
C0LRA8   T1SC34   E7D2J5   A0A212F995   D9D840   A0A2H1W9K6   A0A194QJ85   C8CCR3   T1SBT7   E3UVB8   T1SBT5   T1SBT1   A0A0L7KZH8   A0A212FCV0   A0A2W1BCN7   E0A3F8   J7IL09   E0A3F7   C6KEP2   Q0KKB4   F8UN43   A0A0S1MMB1   B1A8R7   E0A3F6   U3KZM6   A5A3D9   Q86GI6   J7IIA2   E9LK30   J7I5M9   E9LK31   A9CSM0   I3WA85   I3WA86   A0A068F6C3   J7FIB4   E2FZ92   J7G295   E2GLM4   D1CSA1   D6QX79   B5TGR3   A0A023F628   B5AN02   D1LWU2   A0A023F633   T1I0D9   A0A1S5VZD3   B5TGQ9   A0A1Z1JMY7   J3JWS1   A0A346THN6   B4K7C9   A0A224XGB7   A0A346THM2   A5HTV3   A0A1B6KRC2   A0A1L2EC59   K9MV11   A0A1I8P0G5   A0A172JCK2   A0A067QTK9   A0A3G1RKN6   A0A1Z1JNE2   D6WU59   A0A2P0XIF6   F5BYS7   D6WT72   A0A1S5VZG2   A0A1Z1JMY1   A0A165BK16   A0A1S3DAN2   A0A1S3D948   F1C382   A0A240FEJ6   Q5I938   A0A1S3D964   A0A2J7PG88   U3GPH7   J9JMZ6   A0A2J7PG27   F1C378   F1C379   A0A172JCK1   A0A0N1IFZ8   A1E392   W5RXA8   A0A034V9V9   F1C380   Q4ZGJ2   W0I7G2   A0A139WDJ1   A0A0B4L040   A0A212F282  

Pubmed

21362495    22957810    22118469    26354079    19782689    26227816    + More
28756777    17630658    19121390    19320763    18393570    25474469    28187833    28572631    22516182    23537049    17994087    23357950    24845553    29897590    18362917    19820115    21426536    28727798    17651238    17522254    25348373    17129412    25330365   

EMBL

JF836794    AEI58996.1    AB035326    BAF69068.1    DQ311189    ABD36134.1    + More
KY930331    ATL76715.1    FJ862049    ACQ78180.1    AB179657    BAD18974.1    FJ754276    ACN78407.1    JX680669    AGR84216.1    HQ012004    ADV03160.1    AGBW02009614    OWR50325.1    GU945198    KR821069    ADI50267.1    ALL42057.1    ODYU01007205    SOQ49779.1    KQ458671    KPJ05577.1    GQ389711    ACV32640.1    JX680670    AGR84217.1    HM593518    ADP37711.1    JX680677    AGR84224.1    JX680676    AGR84223.1    JTDY01004123    KOB68565.1    AGBW02009136    OWR51575.1    KZ150133    PZC73022.1    HM370511    ADK94699.1    JQ693014    AFQ37587.1    HM370510    ADK94698.1    GQ199477    ACS72236.1    AB251895    BAF03555.1    BABH01042878    JF836795    AEI58997.1    KT225460    ALL42052.1    EU430480    ABZ10939.1    HM370509    ADK94697.1    JX678981    AFU06382.1    EF523381    ABP93405.1    AY220911    AAO65964.1    JQ693015    AFQ37588.1    HQ107971    ADV58254.1    JQ711194    AFQ33498.1    HQ107972    ADV58255.1    AB325801    BAF95560.1    JN863694    AFK93489.2    JN863695    AFK93490.1    KJ701421    AID61521.1    JQ316541    AFO70209.1    HM212645    ADK39311.1    JX112893    AFP54305.1    HM367079    ADO14473.1    DQ093385    ACZ52196.1    HM013709    ADG03465.1    EU934244    ACH85201.1    GBBI01002050    JAC16662.1    EU861391    ACF74975.2    GU074513    ACY71070.1    GBBI01002049    JAC16663.1    ACPB03005879    KX695168    AQP31338.1    EU934240    ACH85197.1    KY705385    ARW29611.1    APGK01039300    BT127689    KB740969    KB632230    AEE62651.1    ENN76739.1    ERL90378.1    MG265913    AXU24969.1    CH933806    EDW14253.1    GFTR01007568    JAW08858.1    MG265899    AXU24955.1    EF569673    ABQ39970.1    GEBQ01026193    JAT13784.1    KT003964    ANJ86404.1    JX627810    AFX84560.1    KU311038    AMQ77288.1    KK853289    KDR08926.1    MF773976    AXB26576.1    KY705383    ARW29609.1    KQ971352    EFA07459.1    EFA07510.1    KY661325    AVA17412.1    JF421286    AEB52075.1    KQ971354    EFA07173.1    KX976473    AQP31363.1    KY705384    ARW29610.1    KU159184    AMX23517.1    HQ184405    ADX42270.1    KY231148    ARQ84028.1    AY842477    AAW32099.2    NEVH01025635    PNF15343.1    KF018929    AGT99186.1    ABLF02040542    PNF15290.1    HQ184404    ADX42267.1    ADX42268.1    KU311037    AMQ77287.1    KQ460126    KPJ17595.1    EF103584    ABL06948.1    KF771049    AHG94986.1    GAKP01020060    JAC38892.1    ADX42269.1    DQ017057    AAY28732.1    KF731995    AHF81959.1    KQ971357    KYB26038.1    KC620440    AHE77387.1    AGBW02010783    OWR47855.1   

Proteomes

UP000007151    UP000053268    UP000037510    UP000005204    UP000015103    UP000019118    + More
UP000030742    UP000009192    UP000095300    UP000027135    UP000007266    UP000079169    UP000235965    UP000007819    UP000053240   

PRIDE

F8UN42    A6P319    Q2F683    F8UN43   

Pfam

PF00012   HSP70

Interpro

IPR018181   Heat_shock_70_CS        + More
IPR029048   HSP70_C_sf       
IPR013126   Hsp_70_fam       
IPR029047   HSP70_peptide-bd_sf       

SUPFAM

SSF100920   SSF100920        + More
SSF100934   SSF100934       

Gene 3D

1.20.1270.10     2.60.34.10    

ProteinModelPortal

F8UN42   A6P319   Q2F683   A0A2C9PHS1   C4P3P9   Q6L6T3   + More
C0LRA8   T1SC34   E7D2J5   A0A212F995   D9D840   A0A2H1W9K6   A0A194QJ85   C8CCR3   T1SBT7   E3UVB8   T1SBT5   T1SBT1   A0A0L7KZH8   A0A212FCV0   A0A2W1BCN7   E0A3F8   J7IL09   E0A3F7   C6KEP2   Q0KKB4   F8UN43   A0A0S1MMB1   B1A8R7   E0A3F6   U3KZM6   A5A3D9   Q86GI6   J7IIA2   E9LK30   J7I5M9   E9LK31   A9CSM0   I3WA85   I3WA86   A0A068F6C3   J7FIB4   E2FZ92   J7G295   E2GLM4   D1CSA1   D6QX79   B5TGR3   A0A023F628   B5AN02   D1LWU2   A0A023F633   T1I0D9   A0A1S5VZD3   B5TGQ9   A0A1Z1JMY7   J3JWS1   A0A346THN6   B4K7C9   A0A224XGB7   A0A346THM2   A5HTV3   A0A1B6KRC2   A0A1L2EC59   K9MV11   A0A1I8P0G5   A0A172JCK2   A0A067QTK9   A0A3G1RKN6   A0A1Z1JNE2   D6WU59   A0A2P0XIF6   F5BYS7   D6WT72   A0A1S5VZG2   A0A1Z1JMY1   A0A165BK16   A0A1S3DAN2   A0A1S3D948   F1C382   A0A240FEJ6   Q5I938   A0A1S3D964   A0A2J7PG88   U3GPH7   J9JMZ6   A0A2J7PG27   F1C378   F1C379   A0A172JCK1   A0A0N1IFZ8   A1E392   W5RXA8   A0A034V9V9   F1C380   Q4ZGJ2   W0I7G2   A0A139WDJ1   A0A0B4L040   A0A212F282  

PDB

5FPN     E-value=0,     Score=2208

KEGG

733093    K03283 heat shock 70kDa protein 1/2/6/8 | (RefSeq) Hsp-70; heat shock protein 70 A1

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)
04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)
04144    Endocytosis - Bombyx mori (domestic silkworm)
04213    Longevity regulating pathway - multiple species - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0031072   GO:0051082   GO:0006986   GO:0034605   GO:0034620   GO:0044183   GO:0005829   GO:0005737   GO:0042026   GO:0051085   GO:0016887   GO:0051787   GO:0042623   GO:0016021  

PANTHER

PTHR19375  

Length:

640

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00495

Exp number, first 60 AAs:

0.00042

Total prob of N-in:

0.00025

outside

1  -  640

 

 

Pi

434.803716

Theta

238.206398

Tajima's D

2.440705

CLR

0.296102

CSRT

0.936153192340383

Interpretation

Uncertain