SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO16079  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA004573
Annotation
PREDICTED:_probable_small_nuclear_ribonucleoprotein_G_[Papilio_polytes]
Full name
Small nuclear ribonucleoprotein G       + More
Probable small nuclear ribonucleoprotein G      
Alternative Name
Sm protein G
Location in the cell
Cytoplasmic   Reliability : 1.285 Mitochondrial   Reliability : 1.34 Nuclear   Reliability : 1.281
 

Sequence

CDS
ATGTCAAAAGCACATCCACCAGAATTGAAAAAATTCATGGACAAAAAATTGTCAATAAAGCTGAATGCGGGTCGCGCTGTTACCGGTGTGTTGCGCGGTTTTGATCCATTCATGAATTTAGTTCTTGATGAATCAGTCGAGGAGTGTAAAGACGGTCAGCGTAACAATGTTGGGATGGTGGTTAGTATATTTTCAAGAACACTCTAA
Protein
MSKAHPPELKKFMDKKLSIKLNAGRAVTGVLRGFDPFMNLVLDESVEECKDGQRNNVGMVVSIFSRTL

Summary

Description
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly (PubMed:18621711). Plays role in pre-mRNA splicing as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome (By similarity).
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
Subunit
Interacts with the SMN complex (PubMed:18621711). Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Most spliceosomal snRNPs contain a common set of Sm proteins, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Component of the U1 snRNP. Component of the U4/U6-U5 tri-snRNP complex. Component of the U7 snRNP complex. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome (By similarity).
Similarity
Belongs to the snRNP Sm proteins family.
Keywords
Complete proteome   Cytoplasm   mRNA processing   mRNA splicing   Nucleus   Reference proteome   Ribonucleoprotein   RNA-binding   Spliceosome  
Feature
chain  Probable small nuclear ribonucleoprotein G
EMBL
BABH01025664    AGBW02013765    OWR42848.1    GAIX01006125    JAA86435.1    AGBW02010527    + More
OWR48341.1    KZ150133    PZC73033.1    NWSH01000008    PCG80962.1    ODYU01012560    SOQ58955.1    DQ443237    ABF51326.1    KQ458671    KPJ05586.1    JTDY01009742    KOB62850.1    GL445463    EFN89534.1    GGFJ01011329    MBW60470.1    GGFK01012582    MBW45903.1    ADMH02000776    ETN65074.1    GFDL01013981    JAV21064.1    AXCM01000657    AXCN02001472    DS231849    EDS36913.1    AAAB01008859    EAA07689.2    APCN01000254    NNAY01001404    OXU24087.1    APGK01050286    BT128583    KB741169    KB632294    AEE63540.1    ENN73310.1    ERL91667.1    AY961514    AAX62416.1    CH477529    EAT39487.1    JXUM01098402    GAPW01006794    GAPW01006793    KQ564417    JAC06804.1    KXJ72321.1    KZ288287    PBC29437.1    GL762231    EFZ21774.1    GL442221    EFN63758.1    JTDY01003063    KOB70228.1    KQ435180    KZC15016.1    KQ971372    EFA09436.1    KQ414940    KOC59224.1    KQ435879    KOX69865.1    KK107323    QOIP01000002    EZA52580.1    RLU25776.1    GL888633    EGI58712.1    ADTU01008099    AJWK01019865    GFDF01008459    JAV05625.1    CM000162    EDX01941.1    CH902622    EDV34329.2    CH954180    EDV46391.1    CCAG010019526    JXJN01000167    JRES01000455    KNC31047.1    GFDG01000495    JAV18304.1    DS235797    EEB17197.1    OUUW01000005    SPP80234.1    CM000070    EDY68092.1    CH479179    EDW24260.1    CP026253    AWP09100.1    CM000366    EDX18105.1    KX531270    ANY27080.1    CH480832    EDW46158.1    AE014298    AY070698    AY113538    AAL48169.1    KK852781    KDR16631.1    GL732601    EFX72260.1    LRGB01000311    KZS19790.1    GANO01000914    JAB58957.1    AFYH01012359    AFYH01012360    JO842310    AEO33927.1    AMQN01006382    KB298218    ELU09428.1    PYGN01000512    PSN45044.1    CH940655    EDW66307.1    CH933814    EDW05560.1    GDIQ01042541    JAN52196.1    CP012528    ALC49974.1    CH916370    EDV99987.1    GFPF01011793    MAA22939.1    GACK01007235    JAA57799.1    GEFH01003347    JAP65234.1    EZ000280    ACG76261.1    CH964239    EDW82276.1    GBBM01003225    JAC32193.1    GFAA01000659    JAU02776.1    GBBK01004487    JAC19995.1    GBBL01002425    JAC24895.1    GFAC01007144    JAT92044.1    LJIJ01000112    ODN02423.1    CVRI01000047    CRK97219.1   
Pfam
PF01423   LSM
Interpro
IPR010920   LSM_dom_sf        + More
IPR001163   LSM_dom_euk/arc       
IPR034098   Sm_G       
IPR011528   NERD       
SUPFAM
SSF50182   SSF50182       
PDB
6QX9     E-value=1.09086e-21,     Score=248

Ontologies

Topology

Subcellular location
Nucleus  
Cytoplasm   SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.   With evidence from 1 publications.
Cytosol   SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.   With evidence from 1 publications.
Length:
68
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.05328
Exp number, first 60 AAs:
0.05328
Total prob of N-in:
0.21275
outside
1  -  68
 
 

Population Genetic Test Statistics

Pi
66.520574
Theta
105.984053
Tajima's D
-1.167971
CLR
279.451386
CSRT
0.107394630268487
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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