Gene

KWMTBOMO16071  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004570

Annotation

AF141930_1_high_affinity_GABA_transporter_[Trichoplusia_ni]

Location

Bomo_Chr27(+):8102835-8119179      View in EpiBrowser

Full name

Transporter      

Location in the cell

PlasmaMembrane   Reliability : 4.912

CDS

ATGGACGTGAAAAACGATGATATTGAACTTAGCGTGCAGGGAACAAGCAAGCCAAGTGACGTCGCGATCAAATCCAATTTGCCGGAGCGAGAATCCTGGGCCAGCAAGCTAGACTTCATCCTTTCTGTAGTTGGCTTGGCCATTGGACTTGGTAACGTTTGGCGTTTCCCTTACCTCTGTTACAAGAATGGCGGGGGAGCCTTCCTCATTCCTTACTTCCTTACACTCTTCCTCGCTGGTATACCGATGTTTTTCATGGAACTGGCCATGGGACAAATGCTGACGATTGGAGGCCTCGGCGTTTTTAAGATCGCCCCGATTTTTAAAGGCATTGGCTACGCTGCAGCCGTGATGTCCTGTTGGATGAATGTTTACTACATCGTAATTCTGGCCTGGGCTATATTTTACTTCTTCATGTCGATGCGTTCAGATGTCCCTTGGCGTAATTGCGACAATTACTGGAACACACCGAGTTGCGTGAACCCTTACGATCGTAAGAATCTGACTTGCTGGTCTAGCAAGGATATGTCGACTTATTGCATCCTCAACGGCAAAAACTTCACCAAAGCTATGCTCTCTGATCCGGTCAAGGAATTTTGGGAACGCCGCGCCCTACAGATTTCATCAGGCATCGAGCATATTGGCAACATCCGCTGGGAATTAGCCGGGACCTTGCTTCTCGTTTGGGTTCTGTGTTACTTCTGCATTTGGAAAGGAGTGAGATGGACAGGCAAAGTTGTTTACTTTACTGCACTGTTTCCATACTTTTTGCTTACCGTGCTGTTAATTAGAGGTATAACGTTACCGGGAGCCTTGGAAGGGATAAAGTTCTACGTGATGCCAAACATGTCCAAGCTACTGGAGTCTGAAGTATGGATTGACGCTGTCACTCAAATCTTCTTCTCGTACGGATTAGGCCTGGGCACTTTAGTAGCTCTTGGTAGCTACAACAAGTTCACTAATAATGTTTACAAGGACGCTCTGATAGTCTGCTCTGTTAACTCCAGCACGTCAATGTTTGCTGGTTTCGTCATCTTTTCTGTGGTTGGCTTTATGGCGCATGAACAGCAGCGTCCTGTTGCTGAAGTGGCCGCTTCTGGTCCGGGCTTGGCATTTCTGGCGTACCCATCAGCCGTCCTGCAGTTGCCAGGTGCCCCGCTCTGGTCTTGCCTGTTCTTCTTCATGCTACTCCTCATTGGCTTGGACAGCCAGTTCTGCACCATGGAAGGCTTCGTGACCGCCGTCATCGACGAATGGCCTAAACTCTTGAGAAGGCGAAAGGAAGTGTTCATTGCAATTACTTGCGTTATTTCTTACCTGGTCGGATTGTCTTGTATCTCTGAAGGTGGCATGTACGTTTTTCAAATCCTCGACTCGTACGCTGTCTCTGGTTTCTGTCTGCTGTTCCTCATTTTCTTTGAGTGCGTCTCCATCTCGTGGGCCTTCGGTGTTAACCGTTTCTATGACGGGATCAAGGAAATGATCGGATACTACCCAATGATTTGGTGGAAGTTCTGCTGGGTTGGATTCACTCCTGCCATTTGCATTAGCGTTTTCATCTTCAATCTCGTGCAGTGGACTCCAATCAAATACATGAATTACGAATACCCCTGGTGGTCCCACGCATTCGGATGGTTTACCGCTTTATCTTCGATGTTGTGTATTCCTGGGTACATGGTGTACCTGTGGCGTGTCACCCCCGGAACCTGGCATGAGAAATTCAACACGATCGTACGCATTCCCGAAGACGTGCCATCTCTACGAACAAAGATGCAAGCTGAAGAACAAGCAAAACATGGCAAAGCTTAG

Protein

MDVKNDDIELSVQGTSKPSDVAIKSNLPERESWASKLDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFLIPYFLTLFLAGIPMFFMELAMGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAIFYFFMSMRSDVPWRNCDNYWNTPSCVNPYDRKNLTCWSSKDMSTYCILNGKNFTKAMLSDPVKEFWERRALQISSGIEHIGNIRWELAGTLLLVWVLCYFCIWKGVRWTGKVVYFTALFPYFLLTVLLIRGITLPGALEGIKFYVMPNMSKLLESEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCSVNSSTSMFAGFVIFSVVGFMAHEQQRPVAEVAASGPGLAFLAYPSAVLQLPGAPLWSCLFFFMLLLIGLDSQFCTMEGFVTAVIDEWPKLLRRRKEVFIAITCVISYLVGLSCISEGGMYVFQILDSYAVSGFCLLFLIFFECVSISWAFGVNRFYDGIKEMIGYYPMIWWKFCWVGFTPAICISVFIFNLVQWTPIKYMNYEYPWWSHAFGWFTALSSMLCIPGYMVYLWRVTPGTWHEKFNTIVRIPEDVPSLRTKMQAEEQAKHGKA

Similarity

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.

Uniprot

Q9NJI0   A0A0N0PA64   A0A2W1BJM4   A0A2A4JHY8   A0A0U4ZU62   A0A0G3VIB4   + More
Q25512   A0A212F833   A0A336L7S6   A0A336MIE5   D6WKL1   A0A1Q3FPR1   E0VAA4   A0A1Y1LKL2   K7IX81   A0A1A9WQD1   E2BL27   A0A0K8U2S1   A0A034WRI5   A0A0C9RDY6   A0A1B0BZS7   A0A1A9YA80   A0A0A1WUC9   A0A026WPT1   B4H889   F4WH84   A0A0M9AD94   A0A158NPD8   A0A088AT93   A0A151X6C7   A0A151IH15   A0A2A3EIS8   B4NHM9   A0A1W4V4Y7   A0A195E530   A0A0K8UT91   A0A0L7R7Y6   A0A1A9ZJY6   E2A4G9   A0A3B0K464   A0A195F4N9   T1I4T4   W8C964   B4LF59   A0A0N7Z8U8   A0A023F218   A0A1W4VH63   B3MZY1   A0A0J7L5P3   A0A067R6S2   B4KVK2   B4J3B5   A0A0A9WTG2   A0A0L0CI82   B4IIX8   B3P9S2   A0A0J9S2H0   B4PW19   A0A1B6GXH5   A0A1B6JT61   Q9V4E7   A0A2J7R419   A0A1B6CA44   Q6NND1   A0A310SS41   A0A2P8YR78   A0A0N1IJP4   A0A1B6KZ53   A0A1B6LMH6   A0A1J1J9R4   Q20C86   A0A1A9VFK0   A0A2H1X1A9   A0A1B0G9X9   A0A182F2W0   W5J7P6   E2AQ81   B0X5H6   A0A182NBS6   A0A026WWC1   A0A182R5I3   A0A182J5D0   A0A182KU05   A0A182KGN3   Q16S73   A0A151XIU1   A0A154PBJ8   A0A182Y0Q0   A0A195FMW4   A0A182MDI6   A0A182HRW0   E9IDG2   A0A2A3EDC6   A0A1S4FRB9   A0A1Q3FQ46   Q6TLC7   A0A1Q3FQ74   A0A084WTZ6   A0A182GV19   Q6TLC6  

Pubmed

10436937    26354079    28756777    7733681    22118469    18362917    + More
19820115    20566863    28004739    20075255    20798317    25348373    25830018    24508170    30249741    17994087    21719571    21347285    24495485    18057021    27129103    25474469    24845553    25401762    26823975    26108605    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    29403074    16507169    20920257    23761445    20966253    17510324    25244985    21282665    24438588    26483478   

EMBL

AF141930    AAF70819.1    KQ458842    KPJ04909.1    KZ150011    PZC75068.1    + More
NWSH01001510    PCG71022.1    AB185110    BAT57339.1    KP657653    RSAL01000078    AKL78878.1    RVE48739.1    L40373    AAA92342.1    AGBW02009801    OWR49896.1    UFQS01002407    UFQT01002407    SSX13976.1    SSX33395.1    UFQT01001356    SSX30192.1    KQ971342    EFA03563.1    GFDL01005455    JAV29590.1    DS235005    EEB10310.1    GEZM01057053    JAV72475.1    AAZX01000612    GL448902    EFN83605.1    GDHF01031548    JAI20766.1    GAKP01002574    JAC56378.1    GBYB01011322    GBYB01011324    GBYB01011325    JAG81089.1    JAG81091.1    JAG81092.1    JXJN01023285    GBXI01012167    JAD02125.1    KK107139    QOIP01000003    EZA57651.1    RLU25181.1    CH479221    EDW34889.1    GL888153    EGI66450.1    KQ435694    KOX80903.1    ADTU01022394    KQ982482    KYQ55859.1    KQ977643    KYN00859.1    KZ288253    PBC30921.1    CH964272    EDW83598.1    KQ979608    KYN20268.1    GDHF01022405    JAI29909.1    KQ414637    KOC66997.1    GL436654    EFN71668.1    OUUW01000017    SPP88994.1    KQ981836    KYN35044.1    ACPB03011743    ACPB03011744    GAMC01002436    GAMC01002435    GAMC01002434    JAC04122.1    CH940647    EDW70247.1    KRF84807.1    GDKW01002347    JAI54248.1    GBBI01003743    JAC14969.1    CH902636    EDV44766.2    LBMM01000654    KMQ97868.1    KK852908    KDR13981.1    CH933809    EDW19473.1    CH916366    EDV97214.1    GBHO01035499    GBHO01035498    GBHO01035497    GBRD01017745    GBRD01017744    GDHC01021994    GDHC01013787    JAG08105.1    JAG08106.1    JAG08107.1    JAG48082.1    JAP96634.1    JAQ04842.1    JRES01000361    KNC31951.1    CH480845    EDW50919.1    CH954184    EDV45235.1    CM002916    KMZ07265.1    CM000161    EDW99324.1    GECZ01013560    GECZ01002644    JAS56209.1    JAS67125.1    GECU01036643    GECU01005354    JAS71063.1    JAT02353.1    AE014135    BT010000    AAF59327.4    AAQ22469.1    NEVH01007816    PNF35570.1    GEDC01027143    JAS10155.1    BT011359    AAR96151.1    KQ760672    OAD59439.1    PYGN01000418    PSN46724.1    KQ459890    KPJ19591.1    GEBQ01023249    JAT16728.1    GEBQ01015110    JAT24867.1    CVRI01000074    CRL08262.1    DQ378286    ABD64799.1    ODYU01012221    SOQ58414.1    CCAG010022213    ADMH02002010    ETN59996.1    GL441701    EFN64415.1    DS232379    EDS40861.1    KK107078    QOIP01000011    EZA60347.1    RLU16916.1    CH477681    EAT37303.1    KQ982080    KYQ60261.1    KQ434869    KZC09232.1    KQ981490    KYN41259.1    AXCM01004029    APCN01001766    GL762454    EFZ21399.1    KZ288293    PBC29021.1    GFDL01005413    JAV29632.1    AY395071    AAQ96727.1    GFDL01005409    JAV29636.1    ATLV01026970    KE525421    KFB53690.1    JXUM01018714    KQ560520    KXJ82007.1    AY395072    AAQ96728.1   

Proteomes

UP000053268    UP000218220    UP000283053    UP000007151    UP000007266    UP000009046    + More
UP000002358    UP000091820    UP000008237    UP000092460    UP000092443    UP000053097    UP000279307    UP000008744    UP000007755    UP000053105    UP000005205    UP000005203    UP000075809    UP000078542    UP000242457    UP000007798    UP000192221    UP000078492    UP000053825    UP000092445    UP000000311    UP000268350    UP000078541    UP000015103    UP000008792    UP000007801    UP000036403    UP000027135    UP000009192    UP000001070    UP000037069    UP000001292    UP000008711    UP000002282    UP000000803    UP000235965    UP000245037    UP000053240    UP000183832    UP000078200    UP000092444    UP000069272    UP000000673    UP000002320    UP000075884    UP000075900    UP000075880    UP000075882    UP000075881    UP000008820    UP000076502    UP000076408    UP000075883    UP000075840    UP000030765    UP000069940    UP000249989   

PRIDE

Q9V4E7    Q6NND1   

Pfam

PF00209   SNF        + More
PF00096   zf-C2H2
PF12657   TFIIIC_delta

Interpro

IPR037272   SNS_sf        + More
IPR000175   Na/ntran_symport       
IPR013087   Znf_C2H2_type       
IPR036236   Znf_C2H2_sf       
IPR024761   TFIIIC_delta_N       
IPR029000   Cyclophilin-like_dom_sf       

SUPFAM

SSF161070   SSF161070        + More
SSF57667   SSF57667       

Gene 3D

2.40.100.10    

ProteinModelPortal

Q9NJI0   A0A0N0PA64   A0A2W1BJM4   A0A2A4JHY8   A0A0U4ZU62   A0A0G3VIB4   + More
Q25512   A0A212F833   A0A336L7S6   A0A336MIE5   D6WKL1   A0A1Q3FPR1   E0VAA4   A0A1Y1LKL2   K7IX81   A0A1A9WQD1   E2BL27   A0A0K8U2S1   A0A034WRI5   A0A0C9RDY6   A0A1B0BZS7   A0A1A9YA80   A0A0A1WUC9   A0A026WPT1   B4H889   F4WH84   A0A0M9AD94   A0A158NPD8   A0A088AT93   A0A151X6C7   A0A151IH15   A0A2A3EIS8   B4NHM9   A0A1W4V4Y7   A0A195E530   A0A0K8UT91   A0A0L7R7Y6   A0A1A9ZJY6   E2A4G9   A0A3B0K464   A0A195F4N9   T1I4T4   W8C964   B4LF59   A0A0N7Z8U8   A0A023F218   A0A1W4VH63   B3MZY1   A0A0J7L5P3   A0A067R6S2   B4KVK2   B4J3B5   A0A0A9WTG2   A0A0L0CI82   B4IIX8   B3P9S2   A0A0J9S2H0   B4PW19   A0A1B6GXH5   A0A1B6JT61   Q9V4E7   A0A2J7R419   A0A1B6CA44   Q6NND1   A0A310SS41   A0A2P8YR78   A0A0N1IJP4   A0A1B6KZ53   A0A1B6LMH6   A0A1J1J9R4   Q20C86   A0A1A9VFK0   A0A2H1X1A9   A0A1B0G9X9   A0A182F2W0   W5J7P6   E2AQ81   B0X5H6   A0A182NBS6   A0A026WWC1   A0A182R5I3   A0A182J5D0   A0A182KU05   A0A182KGN3   Q16S73   A0A151XIU1   A0A154PBJ8   A0A182Y0Q0   A0A195FMW4   A0A182MDI6   A0A182HRW0   E9IDG2   A0A2A3EDC6   A0A1S4FRB9   A0A1Q3FQ46   Q6TLC7   A0A1Q3FQ74   A0A084WTZ6   A0A182GV19   Q6TLC6  

PDB

4XPF     E-value=4.32097e-139,     Score=1269

KEGG

101742290    K05034 solute carrier family 6 (neurotransmitter transporter, GABA) member 1 | (RefSeq) sodium- and

GO

GO:0016021   GO:0005328   GO:0003676   GO:0005886   GO:0043005   GO:0005332   GO:0042165   GO:0071260   GO:0097386   GO:0015812   GO:0006836   GO:0016020   GO:0022857   GO:0001678   GO:0005536   GO:0046835   GO:0006281   GO:0006259  

PANTHER

PTHR11616  

Length:

602

Number of predicted TMHs:

13

Exp number of AAs in TMHs:

284.34673

Exp number, first 60 AAs:

19.61672

Total prob of N-in:

0.05249

POSSIBLE N-term signal

sequence

outside

1  -  38

TMhelix

39  -  56

inside

57  -  62

TMhelix

63  -  85

outside

86  -  94

TMhelix

95  -  117

inside

118  -  123

TMhelix

124  -  141

outside

142  -  216

TMhelix

217  -  239

inside

240  -  245

TMhelix

246  -  268

outside

269  -  291

TMhelix

292  -  314

inside

315  -  326

TMhelix

327  -  349

outside

350  -  378

TMhelix

379  -  401

inside

402  -  428

TMhelix

429  -  451

outside

452  -  460

TMhelix

461  -  483

inside

484  -  503

TMhelix

504  -  526

outside

527  -  540

TMhelix

541  -  563

inside

564  -  602

 

 

Pi

324.076623

Theta

170.416225

Tajima's D

2.907882

CLR

0.30676

CSRT

0.973801309934503

Interpretation

Uncertain