Silkworm Genome Informatics Database

Gene

KWMTBOMO16033 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004550

Annotation

PREDICTED:_epidermal_growth_factor_receptor_kinase_substrate_8-like_isoform_X3_[Bombyx_mori]

Location

Bomo_Chr27(+):6946836-6962738 View in EpiBrowser

Location in the cell

Nuclear Reliability : 3.525

CDS

ATGTCCGCGCAATTGGGCCGCGACAGAGAAAGAGAAAGGGATAGAGACAGAGACCGTAGCGGCTCTGGGGGCGAAAGAGACGACGCTTCATCCACAGGCTCCGAGCGTCTATACGAACAAGACATCGCCATATTGAACCGTTGCTTCGACGACATAGAGAAGTTCATAGCAAGATTACAGCATGCGGCTGCAGCTTCAAGGGAGTTGGAGAGGAGGAGAAGATCGCGAGGAGGCAAGCGAGCGGCGGCTGGTGAAGGAATGCTCGCAATGAGAACCCGTCCTCCGCCGGAGCGCGATTTTGTCGATGTCCTGCAGAAATTTAAACTGTCCTTCAATCTGTTGGCACGTTTGAGAGCTCACATCCATGACCCCAATGCTCCGGAGTTGGTTCATTTCTTGTTCACACCGCTGGCGCTTATTGTGGACGCAGCACAGGACGTCGCCGACGGCCGTCTTCCAGCTAGGGTTGTGCAACCTCTCCTCACGAGGGAGGCCTTGAACCTTCTGGCGAATTGCGTGACAAGCAAAGAAACTGAACTGTGGCACTCATTAGGAGACGCTTGGCTGATACCCAGGGAGCAATGGAAAACACAGATACCACCATATCAACCGGTTTTCATGGACGGGTGGACTCCAGATTACCAAGTCGATGACCAACCTTTACGCAGGTCATCGCCCAGACGCAGCGAGCTGGGCAGGGGTACAATGGAACGGGGCGTGGAAAGGAGCGAGGGCGGGCAGGTGGCGGGTTTCACGTTCGAACGAGAGGAGCCCGAGATATACAACGAGCAATACGCTCCGTTCGCCAGAAATAACTTGAGACCACCAATCGGCCGCGAAGATTCGGGCTCCGCTGCCTCATCGCCCGACAGAGAGCCCCCGTATCGCCCCGCAGACCGAGATGAAGATCTGGGTGAAGCGTGGGCCCGGGGCGTTGCGGCCCGGGGAGGTCGCGTTGTGCGCGTCACCTACCCTCGCACTGCGAATAACGATAAAGAGTTAACTGTCGTGAGGGGAGAGTATTTAGAGGTTCTAGACGATTCGAGAAAGTGGTGGAAGGCTCGTAACAGACGCGGCGTGTCAGCGCACGTGCCACACACCATCGTGGCTCCCGCGTTTTCGCCGCCTTCGTCACCACACCTATACCCTAATCCGATATACACACATTACCAGGATGGCGGGGGGAGAGCTTCGGGCGGCAGCAGTCCCACAGCGGCACCGGAGAAACCAGCGCCAAAGATTGAGGCGGCTGCTCCACCGCCCCCGCCGCCGCCTCCTCCACCCCCGGAGCCGCCGTCACCGCCACCCATCAAATCTGATACTTTGAAATCCACCAAATCGATAATGAGTACTGGCGGCAGTCTCCACGATGAACTGAAGCTAGTACTGCCCCAGATACAGCAAAGAAGAAACAAACTCGACATCAAGAAGACTCCAGATATATTCATTGATCAGAAATCGAATCCGGACGAGGTTGTGGAATGGCTCGAAGCAAAGGGTTTCAGCAATGCCGCCCAACGCCAGCTGAGGATGTCGGGACACCAGCTATTCGCGCTGTCCAGATCTCAGCTGGAGAGGGCACTGGGCCAGGATGAGGGGAAACGACTGTACAGCCAAATTTTGGTCCAGAGGAACGTGTCTGGGTACAAGACGACCTCGGCATCAGAGCTTCAGAGCATCCTGAGGAAAGTACGAGAGAAAGTCGAAGTCTCATGA

Protein

MSAQLGRDRERERDRDRDRSGSGGERDDASSTGSERLYEQDIAILNRCFDDIEKFIARLQHAAAASRELERRRRSRGGKRAAAGEGMLAMRTRPPPERDFVDVLQKFKLSFNLLARLRAHIHDPNAPELVHFLFTPLALIVDAAQDVADGRLPARVVQPLLTREALNLLANCVTSKETELWHSLGDAWLIPREQWKTQIPPYQPVFMDGWTPDYQVDDQPLRRSSPRRSELGRGTMERGVERSEGGQVAGFTFEREEPEIYNEQYAPFARNNLRPPIGREDSGSAASSPDREPPYRPADRDEDLGEAWARGVAARGGRVVRVTYPRTANNDKELTVVRGEYLEVLDDSRKWWKARNRRGVSAHVPHTIVAPAFSPPSSPHLYPNPIYTHYQDGGGRASGGSSPTAAPEKPAPKIEAAAPPPPPPPPPPPEPPSPPPIKSDTLKSTKSIMSTGGSLHDELKLVLPQIQQRRNKLDIKKTPDIFIDQKSNPDEVVEWLEAKGFSNAAQRQLRMSGHQLFALSRSQLERALGQDEGKRLYSQILVQRNVSGYKTTSASELQSILRKVREKVEVS

Uniprot

A0A2A4JL59 A0A2A4JLG5 A0A2A4JKR8 A0A2W1BBG4 A0A0N1IIW8 A0A2H1WME9 + More
A0A0P4VXY8 A0A0N7ZB69 A0A0P4VXZ2 E9H625 A0A0P5G1P7 A0A0N8B657 A0A0P5YLT8 A0A0P6IWW4 A0A0N8AG32 A0A0P4W5F0 A0A1V9XXK6

Pubmed

28756777 26354079 21292972 28327890

EMBL

NWSH01001113 PCG72549.1 PCG72548.1 PCG72551.1 KZ150258 PZC71771.1 + More
KQ460077 KPJ17857.1 ODYU01009606 SOQ54156.1 GDRN01088665 JAI60817.1 GDRN01088666 JAI60816.1 GDRN01088661 JAI60820.1 GL732595 EFX72825.1 GDIQ01254594 JAJ97130.1 GDIQ01209003 JAK42722.1 GDIP01055995 JAM47720.1 GDIQ01016410 JAN78327.1 GDIP01150881 LRGB01002722 JAJ72521.1 KZS06454.1 GDRN01088664 GDRN01088663 JAI60818.1 MNPL01002588 OQR78153.1

Proteomes

UP000218220 UP000053240 UP000000305 UP000076858 UP000192247

Pfam

PF18016   SAM_3        + More
PF08416   PTB
PF00018   SH3_1

Interpro

IPR011993   PH-like_dom_sf        + More
IPR033928   EPS8_PTB
IPR013761   SAM/pointed_sf
IPR039801   EPS8-like
IPR041418   SAM_3
IPR013625   PTB
IPR001452   SH3_domain
IPR035462   Eps8_SH3
IPR036028   SH3-like_dom_sf

SUPFAM

SSF50044 SSF50044 + More
SSF47769 SSF47769

Gene 3D

1.10.150.50 2.30.29.30

CDD

cd01210 PTB_EPS8
cd11764 SH3_Eps8

ProteinModelPortal

A0A2A4JL59 A0A2A4JLG5 A0A2A4JKR8 A0A2W1BBG4 A0A0N1IIW8 A0A2H1WME9 + More
A0A0P4VXY8 A0A0N7ZB69 A0A0P4VXZ2 E9H625 A0A0P5G1P7 A0A0N8B657 A0A0P5YLT8 A0A0P6IWW4 A0A0N8AG32 A0A0P4W5F0 A0A1V9XXK6

PDB

1WXB E-value=1.20268e-07, Score=136

KEGG

101735591 K17277 epidermal growth factor receptor kinase substrate 8 | (RefSeq) epidermal growth factor recept

GO

GO:0016301 GO:0003779 GO:0035023 GO:0007266 GO:0005886 GO:0005515 GO:0005524 GO:0004672 GO:0006468 GO:0016791 GO:0007166 GO:0016020 GO:0000287 GO:0006281 GO:0006259

PANTHER

PTHR12287

Length:

571

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00644

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00180

outside

1 - 571

Pi

359.008973

Theta

181.316389

Tajima's D

2.773282

CLR

0.234532

CSRT

0.966351682415879

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics

Multiple alignment of Orthologues

Gene Tree