Gene

KWMTBOMO15967  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005723

Annotation

PREDICTED:_glycine_receptor_subunit_alpha-4_[Papilio_machaon]

Location

Bomo_Chr27(+):4219053-4221273      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.66

CDS

ATGACGGTCTTTTACGCAAGTGCTTTCTTTAAGATACGTCCCCTAATTTTTGCACAATTACTTTTCCTAGGTAACTTCACCTGTTTGGCCGTTGTTTTTAATTTGAGACGTCGCCTTGGATACCACCTTTTCCACACCTACATACCATCGGCGCTCATCGTTGTTATGTCTTGGATTTCATTCTGGATCAAACCCGAAGCCATTCCAGCCAGAGTCACCCTCGGAGTCACTTCATTGTTGACTTTAGCAACACAAAACACCCAATCCCAACAAAGTCTTCCGCCGGTGTCGTATGTCAAAGCAATCGATGTCTGGATGTCATCCTGCTCGGTGTTCGTCTTCTTATCCTTGTTCGAGTTCGCCGTCGTGAATAATTACATGGGCCCCGTCGCCACTAAAGCCATGAAGGGATATTCCGATGAAGACCTGTCCAGGGATTTAGACGCTTTCAAGCACATATTTCCTGGAAGCACGGAGCCTCGAGCGAGTGCGGCTTCAGTGCCACAGTACGACACGTTCTGCAATGGCAGGGAGACGGCCGTTTACATAGATAGATTCAGTCGATTCTTCTTCCCGTTCTCTTTCTTCATATTAAACGTGGTGTATTGGTCCACGTTTTTGTAA

Protein

MTVFYASAFFKIRPLIFAQLLFLGNFTCLAVVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLFEFAVVNNYMGPVATKAMKGYSDEDLSRDLDAFKHIFPGSTEPRASAASVPQYDTFCNGRETAVYIDRFSRFFFPFSFFILNVVYWSTFL

Similarity

Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Uniprot

H9J881   A0A212EJ70   A0A3G9DMN8   A0A0N1IEF9   A0A0N1IQ08   A0A2A4JP73   + More
A0A2H1W5V6   A0A3S2PJT8   Q177R4   W5JKL4   A0A182F6T8   A0A182PKI8   A0A182UN48   A0A182KFT0   A0A182VYZ5   Q7PYL2   A0A182RPU6   A0A182I075   A0A084VHI3   A0A182XVU8   A0A2M4CJE0   A0A182UJ82   A0A182XBD3   A0A182LY69   A0A182KLT7   A0A182J9L9   A0A182QDK8   A0A182NS76   B4QTL1   A0A2J7R413   D6W801   A0A2P8YR57   A0A3Q0JND5   A0A1B0CM64   A0A1W4WKL3   A0A1W4WKB6   A0A336MDT1   A0A034WBM3   A0A1B6LI61   B0WJW2   A0A0P9A011   A0A2S2NNB6   A0A0M4F5D8   B4KE13   A0A3B0K2G3   A0A1W4WDG6   B3P4F2   A0A182GCX0   B4PTF9   D3UAF1   E1JII9   Q8WS32   A0A1W4W1I0   B3M1G5   A0A0C9QKA2   J9K562   A0A1Q3EUP5   A0A1B6DKK2   B4JSX1   A0A154PLZ5   A0A2S2NHX7   B4NIH8   Q294Z2   B4GMH0   A0A195B9B1   A0A232ELY7   Q9VGI0   B4HHX1   A0A0R1E8K5   A0A1B0G9J2   Q0GQR1   B4M4W1   B5SUY9   A0A0C9RN68   A0A0L0CLY6   E2A862   A0A1B1QGD8   A0A026WNJ8   A0A3L8DWG3   A0A087ZTP8   Q8T9R9   A0A1B0A8M5   A0A1B0BKL8   A0A0C9S226   A0A1A9Y6E8   N6TT21   A0A0J7L6J1   A0A0K8V3F7   W8C0U9   A0A1B6E7N4   A0A0A1XPF1   A0A1I8NS14   A0A195E556   A0A1I8M7V0   E9IQU0   A0A0R3NNT3   A8DMU8   A0A158NPJ3   A0A195D0P4   A0A1B6KKM0  

Pubmed

19121390    22118469    26354079    17510324    20920257    23761445    + More
12364791    14747013    17210077    24438588    25244985    20966253    17994087    18362917    19820115    29403074    25348373    26483478    17550304    20087392    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    11714703    11753412    26109357    26109356    15632085    28648823    16902773    26108605    20798317    24508170    30249741    23537049    24495485    25830018    25315136    21282665    17880682    21347285   

EMBL

BABH01038193    BABH01038194    AGBW02014530    OWR41508.1    LC373509    BBD14179.1    + More
KQ458565    KPJ05811.1    KQ459933    KPJ19279.1    NWSH01000851    PCG73847.1    ODYU01006534    SOQ48470.1    RSAL01000012    RVE53511.1    CH477372    EAT42399.1    ADMH02001255    ETN63425.1    AAAB01008987    EAA01674.3    APCN01002053    ATLV01013177    KE524842    KFB37427.1    GGFL01001269    MBW65447.1    AXCM01000991    AXCN02000201    CM000364    EDX13316.1    NEVH01007816    PNF35566.1    KQ971307    EFA11563.2    PYGN01000418    PSN46723.1    AJWK01018258    UFQT01000750    SSX26953.1    GAKP01007779    JAC51173.1    GEBQ01016600    GEBQ01005649    JAT23377.1    JAT34328.1    DS231965    EDS29492.1    CH902617    KPU80154.1    GGMR01006071    MBY18690.1    CP012526    ALC47062.1    CH933806    EDW16034.1    OUUW01000014    SPP88424.1    CH954181    EDV49467.1    JXUM01009440    JXUM01009441    JXUM01009442    JXUM01009443    KQ560283    KXJ83298.1    CM000160    EDW97658.1    FJ851090    ACZ51422.1    AE014297    ACZ94888.1    AY049775    AF382402    AF435470    AAL12211.1    AAL66187.1    AAL74414.1    AAN13530.2    EDV43256.1    GBYB01003994    JAG73761.1    ABLF02012898    ABLF02012900    ABLF02012903    ABLF02012906    ABLF02066860    GFDL01016033    JAV19012.1    GEDC01011075    JAS26223.1    CH916373    EDV94861.1    KQ434977    KZC12901.1    GGMR01004184    MBY16803.1    CH964272    EDW84801.1    CM000070    EAL28820.1    CH479185    EDW38044.1    KQ976542    KYM81128.1    NNAY01003479    OXU19351.1    AF382401    AAF54699.2    AAL66186.1    CH480815    EDW42553.1    KRK03898.1    CCAG010015406    DQ667188    ABG75740.1    CH940652    EDW59672.1    EU308114    ACA13298.1    GBYB01014927    JAG84694.1    JRES01000211    KNC33252.1    GL437497    EFN70374.1    KU532294    ANT80569.1    KK107144    EZA57612.1    QOIP01000003    RLU24840.1    AF467953    AAL76078.1    JXJN01015975    GBYB01014926    JAG84693.1    APGK01020131    KB740167    KB631669    ENN81203.1    ERL85171.1    LBMM01000538    KMQ98109.1    GDHF01018933    JAI33381.1    GAMC01007259    JAB99296.1    GEDC01003372    JAS33926.1    GBXI01001844    JAD12448.1    KQ979608    KYN20293.1    GL764900    EFZ17084.1    KRT01103.1    EF545125    ABU63603.1    KYB29824.1    ADTU01022439    ADTU01022440    ADTU01022441    ADTU01022442    ADTU01022443    ADTU01022444    ADTU01022445    ADTU01022446    KQ977004    KYN06426.1    GEBQ01027986    GEBQ01019979    JAT11991.1    JAT19998.1   

Proteomes

UP000005204    UP000007151    UP000053268    UP000053240    UP000218220    UP000283053    + More
UP000008820    UP000000673    UP000069272    UP000075885    UP000075903    UP000075881    UP000075920    UP000007062    UP000075900    UP000075840    UP000030765    UP000076408    UP000075902    UP000076407    UP000075883    UP000075882    UP000075880    UP000075886    UP000075884    UP000000304    UP000235965    UP000007266    UP000245037    UP000079169    UP000092461    UP000192223    UP000002320    UP000007801    UP000092553    UP000009192    UP000268350    UP000192221    UP000008711    UP000069940    UP000249989    UP000002282    UP000000803    UP000007819    UP000001070    UP000076502    UP000007798    UP000001819    UP000008744    UP000078540    UP000215335    UP000001292    UP000092444    UP000008792    UP000037069    UP000000311    UP000053097    UP000279307    UP000005203    UP000092445    UP000092460    UP000092443    UP000019118    UP000030742    UP000036403    UP000095300    UP000078492    UP000095301    UP000005205    UP000078542   

PRIDE

H9J881    E1JII9    Q8WS32    Q9VGI0    Q8T9R9   

Pfam

PF02932   Neur_chan_memb        + More
PF02931   Neur_chan_LBD
PF00076   RRM_1

Interpro

IPR017877   Myb-like_dom        + More
IPR036719   Neuro-gated_channel_TM_sf       
IPR006029   Neurotrans-gated_channel_TM       
IPR006202   Neur_chan_lig-bd       
IPR006028   GABAA/Glycine_rcpt       
IPR036734   Neur_chan_lig-bd_sf       
IPR006201   Neur_channel       
IPR018000   Neurotransmitter_ion_chnl_CS       
IPR035979   RBD_domain_sf       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR000504   RRM_dom       
IPR034126   MSI_RRM2       

SUPFAM

SSF90112   SSF90112        + More
SSF63712   SSF63712       
SSF54928   SSF54928       

Gene 3D

2.70.170.10     3.30.70.330    

CDD

cd12323  RRM2_MSI

ProteinModelPortal

H9J881   A0A212EJ70   A0A3G9DMN8   A0A0N1IEF9   A0A0N1IQ08   A0A2A4JP73   + More
A0A2H1W5V6   A0A3S2PJT8   Q177R4   W5JKL4   A0A182F6T8   A0A182PKI8   A0A182UN48   A0A182KFT0   A0A182VYZ5   Q7PYL2   A0A182RPU6   A0A182I075   A0A084VHI3   A0A182XVU8   A0A2M4CJE0   A0A182UJ82   A0A182XBD3   A0A182LY69   A0A182KLT7   A0A182J9L9   A0A182QDK8   A0A182NS76   B4QTL1   A0A2J7R413   D6W801   A0A2P8YR57   A0A3Q0JND5   A0A1B0CM64   A0A1W4WKL3   A0A1W4WKB6   A0A336MDT1   A0A034WBM3   A0A1B6LI61   B0WJW2   A0A0P9A011   A0A2S2NNB6   A0A0M4F5D8   B4KE13   A0A3B0K2G3   A0A1W4WDG6   B3P4F2   A0A182GCX0   B4PTF9   D3UAF1   E1JII9   Q8WS32   A0A1W4W1I0   B3M1G5   A0A0C9QKA2   J9K562   A0A1Q3EUP5   A0A1B6DKK2   B4JSX1   A0A154PLZ5   A0A2S2NHX7   B4NIH8   Q294Z2   B4GMH0   A0A195B9B1   A0A232ELY7   Q9VGI0   B4HHX1   A0A0R1E8K5   A0A1B0G9J2   Q0GQR1   B4M4W1   B5SUY9   A0A0C9RN68   A0A0L0CLY6   E2A862   A0A1B1QGD8   A0A026WNJ8   A0A3L8DWG3   A0A087ZTP8   Q8T9R9   A0A1B0A8M5   A0A1B0BKL8   A0A0C9S226   A0A1A9Y6E8   N6TT21   A0A0J7L6J1   A0A0K8V3F7   W8C0U9   A0A1B6E7N4   A0A0A1XPF1   A0A1I8NS14   A0A195E556   A0A1I8M7V0   E9IQU0   A0A0R3NNT3   A8DMU8   A0A158NPJ3   A0A195D0P4   A0A1B6KKM0  

PDB

5VDI     E-value=2.36813e-25,     Score=283

KEGG

101743028    K05397 histamine-gated chloride channel | (RefSeq) uncharacterized LOC101743028

GO

GO:0005886   GO:0005230   GO:0016021   GO:0004888   GO:0006811   GO:0034220   GO:0007268   GO:1902476   GO:0050877   GO:0005254   GO:0007165   GO:0042391   GO:0043005   GO:0005887   GO:0045202   GO:0043052   GO:0019183   GO:0019182   GO:0003723   GO:0006821   GO:0016020   GO:0006810   GO:0005783   GO:0006816   GO:0000287   GO:0006281   GO:0006259   GO:0005216  

PANTHER

PTHR18945  

Length:

207

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

83.92414

Exp number, first 60 AAs:

40.09293

Total prob of N-in:

0.00224

POSSIBLE N-term signal

sequence

outside

1  -  14

TMhelix

15  -  34

inside

35  -  40

TMhelix

41  -  63

outside

64  -  103

TMhelix

104  -  126

inside

127  -  188

TMhelix

189  -  206

outside

207  -  207

 

 

Pi

208.80144

Theta

145.063

Tajima's D

1.325827

CLR

1.155473

CSRT

0.750062496875156

Interpretation

Uncertain