Gene

KWMTBOMO15957

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr27(-):3839832-3843572      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.565

CDS

ATGGCGTGCAACGGTAGGGAAAAACCGCGTTCCATAAAGTTAGCATTTTATAATGCTAACGGACTCGCGCGTCAGCGCGATCAAGTATATGAGTTTCTCCGCGATAATCTCATCGACATCCTTCTGGTGCAGGAGACCTTCCTAAAGCCCTCGCGTCGCGACCCCAAAGTCGCGAATTACGTCATAGTTAGGAATGACAGACTCTCCGCCCGCAAGGGCGGGACTGTCATTTACTATAGGAGGGCCCTGCACTGCGTCCCTCTCGATACTCCCTCGCTCTTACATATCGAGGCGTCAGTGTGCCGCATCGCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCTGACAAACCCCTCCTGAGCAGTGACCTCGAGACACTGTTCGGTATGGGGGACGCGGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGTATTCAACCCCCGACCCCCACGTGCTATCCGTACAACGCCGCGCGTCGTCCGAGCACAATAGATCTGGCACTGCTGAGGAACGTAACTCTGCGCTTGCGCTCCATCGAGGCAATGTCAGAACTCGACTCAGACCACCGACCTGTCGTCATGCAGCTCGGTCGCCCACTCAACCGCGAACCAGATACGAGGACCATGGTGGATTGGAAGAAGCTGGGCACGTGCTTAGCTGACACCGCTCCACCAATCCTCCCTTGCGGCCCGGATTCAACTCCATCCCCCGAGGATACCGTCGAATCCATAAACATCTTCACTGATCACGTCTCGACGGCGATCATAAGATCTTCGAAACAAGTCGATGTGGAGGACTGCTTCCACCGCATCAGACTTTCCCCCGATCTTAGGGACCTCGTTAGAATCAGAAACGCGGCAATCCGGGCCTACGATCGATATCCCACGGATTCAAACCGGACTCGGATGCGTCGCTTACAGCGGGAGGTCAAATCCCGCTTAAGCGACGCCCGAAACGAAAACTGGGATAGTTATTTAGAAGAACTCGCGCCCACTCACCAAGCATACTGGCAACTAGCTAGGACCCTCAAGTCCGAAACTATAGCCACTATGCCGCCTCTCGTACGCCCCTCAGGCCAATCACCGGCTTACGATGACGATGACAAGGCAGAGTTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTCGTCGACAGGGAGGAGGCGATCGATAGCCTACAACCACGGAAAGCTCCCGGCTCCGACGGCATCCGCAACCGCGCGCTTAAACTGTTACCAGCCCAACTGATAACGATGTTGGCCACCATATTAAATGCTGCTATGACGAACTGCATCTTTCCCGCGGCGTGGAAAGAAGCGGACGTTATCGGCATACACAAGCCGGGCAAACCGAAGAACGAAACCGCGAGTTACCGCCCCATCAGTCTCCTCCCGGCGATAGGCAAACTTTACGAACGGCTCCTTCGTAAACGCCTCTGGGACTTCGTATCCGCGAATAAAATTCTTATAGACGAGCAGTTTGGATTCCGCGCCAGACACTCGTGCGTCCATCAAGTGCACCGCCTCACGGAGCACATCTTACTAGGGCTGAACAGGCGGAAACCCATTCCGACAGGAGCCCTCTTCTTCGATATAGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTGATATACAAACTGTATAACATGGGAGTGCCAGACAGGCTCGTGCTCATCATACGAGACTACTTGTCGAACCGTTCGTTCCGATATCGAGTCGAGGGAACGCGTTCCCGGCCCCGTCACGTCACAGCCGGAGTCCCGCAAGGCTCCGCCCTCTCCCCGTTACTATTCAGTTTGTATATTAACGATATACCCCGGTCTCCGGAGACCCATCTGGCGCTCTTCGCCGATGACACCGCCATCTACTACTCGTGTAGGAAGAAGGCGTTGCTTCATCGACGACTTCAGACCGCAGCTACCACCATGGGACAGTGGTTCCGGAAGTGGCGCATCGACATTAACCCCACGAAAAGCACAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAACACCACGCTGAGCATCCCTCTCCCGACTAGGCGCGTCAACACCCCCGCCCCCGCCGTTCGCCCAATCACGATGTACGACCAGCCCATACCGTGGGCCCCGAAGGTCAAATATTTAGGCGTCACCCTCGACAGTAGGATGACATTCCGCCCCCACATCAAGACGGTACGCGATCGTGCCGCCTTCATCCTAGGACGTCTCTACCCGATGATATGTAGGCGAAGTAAAATGTCCCTTAGAAATAAGGTGACACTCTACAAAACTTGCATACGCCCCGTCATGACCTATGCAAGTGTAGTGTTCGCTCACGCAGCCCGCATACACTTAAAATCCTTTCAAATCATTCAATCCCGTTTTTGCAGGATAGCCGTCGGAGCCCCGTGGTTCGTCAGGAACGTCGACCTCCATGACGACCTGGACTTAGAGTCCATCAGTAAGTATCTTCAGTCGGCGTCCATGCGCCACTTCGATAAAGCGGCACGACACGAGAACCCTCTCATCGTGGCCGCCGGTAACTACATTCCCGATCCTGCGGACAGAATGGAAAGCAGTCGACGTCGCCCAAAACACGTCATCTCGGATCCTCCCGATCCACTAACGGTGCTTTTAGTTTGCGGGGTCAGTAAATAA

Protein

MACNGREKPRSIKLAFYNANGLARQRDQVYEFLRDNLIDILLVQETFLKPSRRDPKVANYVIVRNDRLSARKGGTVIYYRRALHCVPLDTPSLLHIEASVCRIALTGHQPIVIASVYLPPDKPLLSSDLETLFGMGDAVILAGDLNCHHTSIQPPTPTCYPYNAARRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPLNREPDTRTMVDWKKLGTCLADTAPPILPCGPDSTPSPEDTVESINIFTDHVSTAIIRSSKQVDVEDCFHRIRLSPDLRDLVRIRNAAIRAYDRYPTDSNRTRMRRLQREVKSRLSDARNENWDSYLEELAPTHQAYWQLARTLKSETIATMPPLVRPSGQSPAYDDDDKAELLADALQEQCTTSTQHADPEHTEFVDREEAIDSLQPRKAPGSDGIRNRALKLLPAQLITMLATILNAAMTNCIFPAAWKEADVIGIHKPGKPKNETASYRPISLLPAIGKLYERLLRKRLWDFVSANKILIDEQFGFRARHSCVHQVHRLTEHILLGLNRRKPIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDYLSNRSFRYRVEGTRSRPRHVTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKKALLHRRLQTAATTMGQWFRKWRIDINPTKSTAVLFKRGRPPNTTLSIPLPTRRVNTPAPAVRPITMYDQPIPWAPKVKYLGVTLDSRMTFRPHIKTVRDRAAFILGRLYPMICRRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARIHLKSFQIIQSRFCRIAVGAPWFVRNVDLHDDLDLESISKYLQSASMRHFDKAARHENPLIVAAGNYIPDPADRMESSRRRPKHVISDPPDPLTVLLVCGVSK

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

Q9XXW0   Q93137   Q9BPQ0   O96546   A0A0N1PFV1   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   A0A2S2PPK8   Q07995   A0A3N5Z7I3   X1WLB2   A0A2S2QEE0   A0A2J7R7D0   A0A224XF24   A0A2M4BD67   A0A2M4BDV6   A0A087UGF5   A0A2M4BD66   A0A2S2Q383   A0A2M4BDA5   A0A2J7QR37   A0A2M4BD62   A0A2J7QY69   A0A2J7PBY3   A0A2M4CV42   A0A2M4CV52   J9KKL3   X1WNI2   A0A2S2NGV8   A0A2J7PU96   A0A2J7Q6J2   A0A2J7QB68   X1WZH0   A0A2M4BD83   A0A224X6S1   J9LFC9   J9LC21   A0A1Y1LKN6   V9GZF1   A0A0A9YJ00   A0A2J7PDM0   A0A224X6R6   A0A2H8TF37   A0A0A9YU04   A0A224X6T4   A0A2J7PVX3   A0A0L0CBP5   K7IN67   A0A1B6EGD8   Q8I7P8   A0A069DZL8   A0A2S2PHL7   A0A224X6Q4   A0A2S2PX53   A0A2S2N814   A0A224XB44   J9M522   A0A2M4BEF4   A0A2M4BEZ9   A0A2S2R9D4   A0A069DX78   A0A2A4IUM2   A0A2S2P698   A0A224X746   Q9NBX4   A0A224X6U5   A0A2J7RE85   Q04135   Q6R811   A0A2S2NPG3   A0A2J7R8R8   Q95SX7   A0A2J7Q0S7   J9KLB1   A0A142LX26   A0A224XJI0   A0A1Y1KFR3   A0A352X8G4   A0A224X6W2   A0A1W7R682   A0A2M4CVK2   Q961V7   A0A2S2PJG2   A0A2H8TKI9  

EC Number

2.7.7.49

Pubmed

10333566    10380107    26354079    28004739    18362917    19820115    + More
25474469    8387152    30086797    1327974    25401762    26108605    20075255    26334808    11405632    1705654    14745026    7753626    12537569    25527032    30148503   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
AF081103    AAC72921.1    KQ459265    KPJ02064.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GBBI01004571    JAC14141.1    GGMR01018716    MBY31335.1    S59870    AAB26437.2    RPOV01000134    RPJ78669.1    ABLF02042518    ABLF02057746    GGMS01006359    MBY75562.1    NEVH01006736    PNF36716.1    GFTR01008038    JAW08388.1    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    KK119692    KFM76444.1    GGFJ01001844    MBW50985.1    GGMS01002992    MBY72195.1    GGFJ01001842    MBW50983.1    NEVH01011985    PNF31054.1    GGFJ01001843    MBW50984.1    NEVH01009134    PNF33528.1    NEVH01027074    PNF13841.1    GGFL01005012    MBW69190.1    GGFL01004957    MBW69135.1    ABLF02029306    ABLF02029314    ABLF02060138    ABLF02008153    ABLF02008462    ABLF02008464    GGMR01003407    MBY16026.1    NEVH01021205    PNF19912.1    NEVH01017470    PNF24199.1    NEVH01016302    PNF25823.1    ABLF02034467    GGFJ01001822    MBW50963.1    GFTR01008271    JAW08155.1    ABLF02023911    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GEZM01053022    JAV74219.1    M95171    AAA29354.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    NEVH01026386    PNF14434.1    GFTR01008269    JAW08157.1    GFXV01000908    MBW12713.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GFTR01008261    JAW08165.1    NEVH01020940    PNF20481.1    JRES01000644    KNC29657.1    GEDC01000337    JAS36961.1    AY180919    AAN87272.1    GBGD01000415    JAC88474.1    GGMR01016296    MBY28915.1    GFTR01008279    JAW08147.1    GGMS01000737    MBY69940.1    GGMR01000676    MBY13295.1    GFTR01008262    JAW08164.1    ABLF02024246    GGFJ01002256    MBW51397.1    GGFJ01002257    MBW51398.1    GGMS01017365    MBY86568.1    GBGD01000389    JAC88500.1    NWSH01007753    PCG62823.1    GGMR01012305    MBY24924.1    GFTR01008151    JAW08275.1    AF237761    AAF81411.1    GFTR01008251    JAW08175.1    NEVH01005277    PNF39135.1    X17551    CAA35587.1    AY508487    AAS13459.1    GGMR01006408    MBY19027.1    NEVH01006721    PNF37225.1    AY060438    AAL25477.1    NEVH01019963    PNF22185.1    ABLF02040174    ABLF02040183    ABLF02055266    KU543673    AMS38352.1    GFTR01008257    JAW08169.1    GEZM01084969    JAV60363.1    DNOY01000259    HBE18313.1    GFTR01008260    JAW08166.1    GEHC01000968    JAV46677.1    GGFL01005121    MBW69299.1    AY047531    AAK77263.1    GGMR01016905    MBY29524.1    GFXV01002840    MBW14645.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000037069    + More
UP000002358    UP000218220   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    Q8I7P8    Q9NBX4    Q04135    + More
Q95SX7    Q961V7   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR036875   Znf_CCHC_sf       
IPR001878   Znf_CCHC       

SUPFAM

SSF56219   SSF56219        + More
SSF57756   SSF57756       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   O96546   A0A0N1PFV1   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   A0A2S2PPK8   Q07995   A0A3N5Z7I3   X1WLB2   A0A2S2QEE0   A0A2J7R7D0   A0A224XF24   A0A2M4BD67   A0A2M4BDV6   A0A087UGF5   A0A2M4BD66   A0A2S2Q383   A0A2M4BDA5   A0A2J7QR37   A0A2M4BD62   A0A2J7QY69   A0A2J7PBY3   A0A2M4CV42   A0A2M4CV52   J9KKL3   X1WNI2   A0A2S2NGV8   A0A2J7PU96   A0A2J7Q6J2   A0A2J7QB68   X1WZH0   A0A2M4BD83   A0A224X6S1   J9LFC9   J9LC21   A0A1Y1LKN6   V9GZF1   A0A0A9YJ00   A0A2J7PDM0   A0A224X6R6   A0A2H8TF37   A0A0A9YU04   A0A224X6T4   A0A2J7PVX3   A0A0L0CBP5   K7IN67   A0A1B6EGD8   Q8I7P8   A0A069DZL8   A0A2S2PHL7   A0A224X6Q4   A0A2S2PX53   A0A2S2N814   A0A224XB44   J9M522   A0A2M4BEF4   A0A2M4BEZ9   A0A2S2R9D4   A0A069DX78   A0A2A4IUM2   A0A2S2P698   A0A224X746   Q9NBX4   A0A224X6U5   A0A2J7RE85   Q04135   Q6R811   A0A2S2NPG3   A0A2J7R8R8   Q95SX7   A0A2J7Q0S7   J9KLB1   A0A142LX26   A0A224XJI0   A0A1Y1KFR3   A0A352X8G4   A0A224X6W2   A0A1W7R682   A0A2M4CVK2   Q961V7   A0A2S2PJG2   A0A2H8TKI9  

PDB

6AR3     E-value=0.00124215,     Score=103

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313   GO:0008270   GO:0003676  

Length:

899

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.479480000000001

Exp number, first 60 AAs:

0.00034

Total prob of N-in:

0.00544

outside

1  -  899

 

 

Pi

10.444574

Theta

14.766785

Tajima's D

0

CLR

1.151448

CSRT

0.378931053447328

Interpretation

Uncertain