Gene

KWMTBOMO15938  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013383

Annotation

PREDICTED:_trypsin-1-like_[Amyelois_transitella]

Location

Bomo_Chr27(-):2810022-2813393      View in EpiBrowser

Full name

Trypsin-2       + More
Trypsin 5G1      
Trypsin-1      
Trypsin-7      
Trypsin-3      

Alternative Name

Antryp2
Antryp1

Location in the cell

Cytoplasmic   Reliability : 2.146

CDS

ATGGCAGCCCAACCCGAGACCAAGTCTAAGAGCTTTGGAGAAGTCCTTAGAGGACAGATTTGCGAAAAGCTTCGCAAAAAGTCGACATTCATTAAGGCCGGCTCTAAGCACATACACAAAGGGAAGAAAGTGAAGATCAAGGAGCATTACATACATCCGCTCTGGGGTGCCAAAAATAAGGAACATCCCTTCGATTACGACTTCCAATTGCTGGAGCTGGCTGAGCCTCTGAGCTTCGACGACAATATTCAGTCATTGAAAATAGCGCATATAGAAGATATGGTGGTCGGAAAGATTATAACGGTCACCGGTTGGGGTAACATAGAAGAAAACGGCCCCTACTCGAACGTGCTCCGAGCCGTAAGGATTCCTATAATATCCAAATCAATCTGCCAGAGTGTTCCATTTCCGTATTTCAGAGGAACTTTGTCATCTCGAATGTTCTGCGCTGGGTTTGCTGAAGAAAAGAAAGATGCTTGTCAGGGCGACTCAGGCGGACCAGCGGTTTCAGACAATCGTCTTTTAGGCATGGTGTCCTTCGGCTACGGCTGCGCAACCCCAGGTTCCTATGGAGTCTACAGCAAAGTGGCGAAAGTCAGGCCCTGGATAGAAGAAGTGACCGGCCTAAAATTAGATTAG

Protein

MAAQPETKSKSFGEVLRGQICEKLRKKSTFIKAGSKHIHKGKKVKIKEHYIHPLWGAKNKEHPFDYDFQLLELAEPLSFDDNIQSLKIAHIEDMVVGKIITVTGWGNIEENGPYSNVLRAVRIPIISKSICQSVPFPYFRGTLSSRMFCAGFAEEKKDACQGDSGGPAVSDNRLLGMVSFGYGCATPGSYGVYSKVAKVRPWIEEVTGLKLD

Description

Major function may be to aid in digestion of the blood meal.
Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female.

Catalytic Activity

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Similarity

Belongs to the peptidase S1 family.

Keywords

Complete proteome   Digestion   Disulfide bond   Hydrolase   Protease   Reference proteome   Secreted   Serine protease   Signal   Zymogen  

Feature

propeptide  Activation peptide
chain  Trypsin-2

Uniprot

H9JV20   A0A3S2L8X9   D9HQ20   A0A2H1W6E8   D9HQ62   A0A0N1I2N0   + More
A0A0N1PJ57   G9D477   G9D476   G9D473   G9D469   G9D468   G9D471   G9D470   G9D465   G9D475   G9D467   G9D474   A0A2A4K562   A0A2W1BG09   A0A2H1W9P5   A0A0N1IHQ9   A0A194PVU9   D9HQ40   A0A240PL34   A0A1Y9GKV0   Q16TM1   A0A182U9U3   P35036   A0A2K7P6D6   P29787   A0A1Y9J0J4   A0A2C9GTQ1   A0A182T760   A0A182PCQ7   Q17086   C8CGF6   A0A182VGJ0   U5EZJ4   A0A1Y9HEI4   A0A1I8PQ52   P35035   A0A1Y9J180   A0A182ICF6   A0A182TKI7   A0A1Y9GKU7   A0A182VG56   A0A2C9GTY9   A0A182XL71   A0A182L0V6   A0A182V8R1   A0A1L8E8C4   P35041   A0A212FBT4   A0A1Y9HES5   A0A182U4C7   A0A182J896   A0A220K8K3   A0A182T724   A0A182M5F2   D9HQ78   B4JQ66   F4MI42   B4KFB8   A0A182KHH7   H9GEM5   A0A1Y9J184   A0A182GET7   A0A1Y9GLX5   A0A2C9GTS0   A0A088A9M1   P35037   A0A1S4GXU9   A0A182GET6   G9D4L7   A0A182TJQ8   B4MU78   Q16TL9   Q16TL8   Q16ID8   G9D4L3   A0A0L7RFI3   A0A1L8E9T7   U5EZ49   A0A1B3TNW7   A0A1L8E9Y2   A0A1Y9HDX0   A0A182V8D5   B0WBW1   G9D4L9   A0A0J7KG36  

EC Number

3.4.21.4

Pubmed

19121390    20375075    21967427    26354079    28756777    17510324    + More
8335004    7498434    12364791    9087545    20966253    20100490    22118469    28630352    17994087    21569254    21881562    26483478    27553646   

EMBL

BABH01026404    BABH01026405    RSAL01000085    RVE48362.1    HM023775    JF777125    + More
ADJ58508.1    AEU11470.1    ODYU01006610    SOQ48603.1    HM023817    JF777119    ADJ58550.1    AEU11464.1    KQ459572    KPI99586.1    KQ460448    KPJ14673.1    JF777130    AEU11475.1    JF777129    AEU11474.1    JF777126    AEU11471.1    JF777122    AEU11467.1    JF777121    AEU11466.1    JF777124    AEU11469.1    JF777123    AEU11468.1    JF777118    AEU11463.1    JF777128    AEU11473.1    JF777120    AEU11465.1    JF777127    AEU11472.1    NWSH01000148    PCG79058.1    KZ150532    PZC70593.1    ODYU01007221    SOQ49809.1    KQ460466    KPJ14599.1    KQ459597    KPI95255.1    HM023795    JF777269    ADJ58528.1    AEU11614.1    APCN01000798    CH477645    EAT37856.1    Z18890    Z22930    AAAB01008964    CH478086    X64363    U52359    AAA97479.1    GQ398048    ACV07665.1    GANO01000688    JAB59183.1    Z18889    GFDG01003967    JAV14832.1    AGBW02009280    OWR51183.1    MF319702    ASJ26416.1    AXCM01007963    AXCM01007964    HM023833    JF777262    ADJ58566.1    AEU11607.1    CH916372    EDV99046.1    EZ933290    ADJ57671.1    CH933807    EDW12018.1    AAWZ02033504    JXUM01058532    KQ562007    KXJ76927.1    JXUM01058527    KXJ76926.1    JF777270    AEU11615.1    CH963852    EDW75667.2    EAT37858.1    EAT37859.1    GQ398049    ACV07666.1    EAT34028.1    JF777266    AEU11611.1    KQ414606    KOC69605.1    GFDG01003433    JAV15366.1    GANO01001434    JAB58437.1    KU925725    AOG75350.1    GFDG01003370    JAV15429.1    DS231882    EDS42891.1    JF777272    AEU11617.1    LBMM01008021    KMQ89214.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000053240    UP000218220    UP000075885    + More
UP000075840    UP000008820    UP000075902    UP000007062    UP000076407    UP000075882    UP000075901    UP000075903    UP000075900    UP000095300    UP000007151    UP000075880    UP000075883    UP000001070    UP000009192    UP000075881    UP000001646    UP000069940    UP000249989    UP000005203    UP000007798    UP000053825    UP000002320    UP000036403   

PRIDE

H9JV20    P35036    P29787    P35035    P35041    A0A088A9M1    + More

Pfam

PF00089   Trypsin

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR001314   Peptidase_S1A       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR012224   Pept_S1A_FX       
IPR033116   TRYPSIN_SER       

SUPFAM

SSF50494   SSF50494       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9JV20   A0A3S2L8X9   D9HQ20   A0A2H1W6E8   D9HQ62   A0A0N1I2N0   + More
A0A0N1PJ57   G9D477   G9D476   G9D473   G9D469   G9D468   G9D471   G9D470   G9D465   G9D475   G9D467   G9D474   A0A2A4K562   A0A2W1BG09   A0A2H1W9P5   A0A0N1IHQ9   A0A194PVU9   D9HQ40   A0A240PL34   A0A1Y9GKV0   Q16TM1   A0A182U9U3   P35036   A0A2K7P6D6   P29787   A0A1Y9J0J4   A0A2C9GTQ1   A0A182T760   A0A182PCQ7   Q17086   C8CGF6   A0A182VGJ0   U5EZJ4   A0A1Y9HEI4   A0A1I8PQ52   P35035   A0A1Y9J180   A0A182ICF6   A0A182TKI7   A0A1Y9GKU7   A0A182VG56   A0A2C9GTY9   A0A182XL71   A0A182L0V6   A0A182V8R1   A0A1L8E8C4   P35041   A0A212FBT4   A0A1Y9HES5   A0A182U4C7   A0A182J896   A0A220K8K3   A0A182T724   A0A182M5F2   D9HQ78   B4JQ66   F4MI42   B4KFB8   A0A182KHH7   H9GEM5   A0A1Y9J184   A0A182GET7   A0A1Y9GLX5   A0A2C9GTS0   A0A088A9M1   P35037   A0A1S4GXU9   A0A182GET6   G9D4L7   A0A182TJQ8   B4MU78   Q16TL9   Q16TL8   Q16ID8   G9D4L3   A0A0L7RFI3   A0A1L8E9T7   U5EZ49   A0A1B3TNW7   A0A1L8E9Y2   A0A1Y9HDX0   A0A182V8D5   B0WBW1   G9D4L9   A0A0J7KG36  

PDB

5CE1     E-value=7.40755e-26,     Score=287

KEGG

101741706    K01312 trypsin [EC:3.4.21.4] | (RefSeq) trypsin-1-like

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0004252   GO:0005509   GO:0016021   GO:0007596   GO:0005576   GO:0007586   GO:0008236   GO:0005615   GO:0006508   GO:0003723   GO:0006811   GO:0005220   GO:0005783   GO:0006816   GO:0000287   GO:0006281   GO:0006259  

Subcellular location

Secreted  
  

Length:

212

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.39846

Exp number, first 60 AAs:

0

Total prob of N-in:

0.17791

outside

1  -  212

 

 

Pi

149.368091

Theta

136.553745

Tajima's D

0.464276

CLR

0.138202

CSRT

0.504324783760812

Interpretation

Uncertain