Gene

KWMTBOMO15879  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013369

Annotation

PREDICTED:_vinculin_[Bombyx_mori]

Location

Bomo_Chr27(+):623022-633164      View in EpiBrowser

Full name

Vinculin      

Location in the cell

Nuclear   Reliability : 2.422

CDS

ATGTGCGGGCGCGCCGCCGCCGCCGCGCGCACCGTGGCCGCGGGCGCGGGACACCACAAGCGGCTCGCCGACCAGCTGCTGCACTACGCCGCGCAGGTGGAGAAGCTCTCGCCTCAAGTTATCGCGGCTGGTAAAATCCGGTTCTACAACCCGGACAGCAAGGTGGCGGAGGAACACTTCGACAACCTGAAGGGGCAGTACTCGGAGGCGGTGCTGCGGGTGCGGGATCTGTGCGACCAGGCCGTCGACCCCCTGGACTTCGTCAGGACAGCCGGCGAGCTGATGCAGAAGCACACGTACCTGTGCGAGGACGCCATCCGCAACAACGACTCGCAGAAGATGGTGGATAACACTTCGGCTATAGCCAGGCTGGCCAACCGCGTGCTGCTGGTGGGCGGGTCGGAGCGCGACAACACGGAGGACGGCGAGTTCGCCCGCGCGCTGGACGCCGCCCACCGCCGCCTGCAGGCCGCCATCCCCGCCGCCGTGCGCAGGGCCAAGGGCGTGGCGCAGGCAGACCGCGCGCAGCTGCCGCACTGGAGGGCCGCCAACGCAGAGATAATTAAAGCAGCGAGCGAAATGGAATCGGCACTGGGGCAGCACTACGCTCCCCCGCCCCCGCCGCCCCCGCCCCCGGTCCCCGCGCCAGTGGAGGACAATCTTAGCAGGCTGACGTCACGCCTGGAGGTGTCGGCGCCGCCGCGCCCCCCGCCGCCCTCAGCCGCCGCCCCGCCGCGCCCCCCGCCCCCCGCTGACACTGACGACGAGGGGGAGGACATCTTCAGGAGACAACCGCATCCCAGCCAACCTATACTGGTCGCCGCCCACAACCTGCACAAGGCGGTCCGCGAGTGGTCCTCGAAGGACAACGAAATCATCGCGGCGGCCAAGCGGATGGCGATCCTCATGGCCAGGCTCTCCGAACTGGTCCGCTCCGATTCTAAAGGCAGCAAACGGGAGCTCATAGCGACGGCGAAGGCGATCGCTGAGGCTTCCGAGGAGGTGACCAGACTCGCCAAGAAGCTGGCCCTCGAGTGCACCGACAAGAGGATCAGGACTAATCTGCTGCAAGTGTGCGAGAGGATCCCGACCATCGGGACGCAGCTGAAGATCCTCTCGACCGTGAAGGCCACCATGCTTGGAGCACAAGGCAGCGAAGAGGACCAAGAGGCCACCGAGATGCTGGTCGGCAACGCTCAAAACCTGATGCAGAGTGTCAAGGAGACGGTGAAAGCATCCGAAGGCGCATCAATCAAGATCCGCACGGAGCAGGGCGGCTACCGGCTGCGCTGGGTCCGCCGGTCGCCCTGGTACCAGATCTAA

Protein

MCGRAAAAARTVAAGAGHHKRLADQLLHYAAQVEKLSPQVIAAGKIRFYNPDSKVAEEHFDNLKGQYSEAVLRVRDLCDQAVDPLDFVRTAGELMQKHTYLCEDAIRNNDSQKMVDNTSAIARLANRVLLVGGSERDNTEDGEFARALDAAHRRLQAAIPAAVRRAKGVAQADRAQLPHWRAANAEIIKAASEMESALGQHYAPPPPPPPPPVPAPVEDNLSRLTSRLEVSAPPRPPPPSAAAPPRPPPPADTDDEGEDIFRRQPHPSQPILVAAHNLHKAVREWSSKDNEIIAAAKRMAILMARLSELVRSDSKGSKRELIATAKAIAEASEEVTRLAKKLALECTDKRIRTNLLQVCERIPTIGTQLKILSTVKATMLGAQGSEEDQEATEMLVGNAQNLMQSVKETVKASEGASIKIRTEQGGYRLRWVRRSPWYQI

Description

Involved in cell adhesion. May be involved in the attachment of the actin-based microfilaments to the plasma membrane.

Subunit

Exhibits self-association properties.

Similarity

Belongs to the vinculin/alpha-catenin family.

Keywords

Actin-binding   Cell adhesion   Cell junction   Cell membrane   Complete proteome   Cytoplasm   Cytoskeleton   Membrane   Phosphoprotein   Reference proteome   Repeat  

Feature

chain  Vinculin

Uniprot

A0A2H1VC97   H9JV06   A0A3S2TTN0   A0A194PP83   A0A2M3Z6A1   A0A2M4A655   + More
A0A2M4BCB1   A0A182SU74   A0A182FG03   A0A182JNC5   A0A336MYC4   A0A336MF54   A0A182LRR4   A0A182WJ44   A0A182PQA9   A0A182RNF3   A0A084WNF9   A0A182U7M2   A0A182XZ03   A0A182X3L7   Q7QJI4   A0A182I3F2   B0X394   A0A182KRH3   A0A182VMB9   A0A023EWN7   A0A182NHR3   A0A182IJR2   A0A182HA48   A0A1J1HT91   A0A1W4VS88   A0A182Q5G7   B4Q189   B3MYS8   B3P8Y8   X2JAB9   O46037   A0A3B0JTC8   Q178I1   A0A1B0CGY0   Q29JL3   W8BFM7   Q24584   A0A1L8E3V2   B4NQ05   U5EZL2   A0A034VPM4   A0A0K8VFK9   A0A0Q9WIP8   A0A0A1XKI0   B4M7C8   A0A0M4FA38   T1PGN4   A0A0Q9XNY7   B4L5U0   A0A0L0BLR2   W5JGR3   A0A336M9K2   N6UAG2   A0A1A9WVM6   A0A1B6HE01   A0A1I8PZF7   A0A1D2MNR5   A0A2J7RNG9   A0A1B6K314   K7IMW4   A0A1B6I1Z1   A0A1B6L0M2   A0A1B6K8G4   A0A067QS50   A0A1A9UW50   A0A0P4WJ01   A0A0P4VGZ5   A0A195EWY0   A0A069DWV1   A0A1B6JBY8   A0A0P6ELG4   F4WTB1   A0A158NN08   A0A151JBF5   A0A0J7KY03   A0A131XPW9   A0A0P5FYW5   A0A0P4ZST5   A0A0P5BQX9   A0A0P5G2L4   A0A1B6LZ15   A0A224Z5F6   A0A131YF27   A0A1E1XF93   A0A131YYR8   E2BTN6   A0A0N8BBF2   A0A151WUQ8   A0A1B6G3E0   A0A2R5LHL7   A0A1B6CKP3   B4I9S2   E9HAB0   A0A0P5JWL5  

Pubmed

19121390    26354079    24438588    25244985    12364791    14747013    + More
17210077    20966253    24945155    26483478    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    9280281    10731137    12537569    17372656    17510324    15632085    23185243    24495485    25348373    25830018    25315136    18057021    26108605    20920257    23761445    23537049    27289101    20075255    24845553    27129103    26334808    21719571    21347285    28049606    28797301    26830274    28503490    20798317    21292972   

EMBL

ODYU01001771    SOQ38435.1    BABH01037485    BABH01037486    BABH01037487    RSAL01000002    + More
RVE54937.1    KQ459597    KPI95246.1    GGFM01003306    MBW24057.1    GGFK01002938    MBW36259.1    GGFJ01001548    MBW50689.1    UFQT01001504    SSX30858.1    UFQS01000750    UFQT01000750    SSX06610.1    SSX26957.1    AXCM01010044    ATLV01024599    KE525352    KFB51753.1    AAAB01008807    EAA04738.1    APCN01000207    DS232311    EDS39596.1    GAPW01000126    JAC13472.1    JXUM01122085    KQ566568    KXJ70027.1    CVRI01000020    CRK91221.1    AXCN02000376    CM000162    EDX01396.2    CH902632    EDV32772.1    CH954183    EDV45593.1    AE014298    AHN59284.1    AHN59285.1    AL009193    AY128501    OUUW01000003    SPP78720.1    CH477363    EAT42601.1    AJWK01011708    CH379063    EAL32288.2    KRT05813.1    GAMC01009048    GAMC01009047    JAB97507.1    X96601    CAA65421.1    GFDF01000780    JAV13304.1    CH964291    EDW86230.1    GANO01000589    JAB59282.1    GAKP01015203    GAKP01015202    JAC43750.1    GDHF01014667    GDHF01004794    JAI37647.1    JAI47520.1    CH940653    KRF80763.1    GBXI01014012    GBXI01012659    GBXI01003214    GBXI01002835    JAD00280.1    JAD01633.1    JAD11078.1    JAD11457.1    EDW62695.1    CP012528    ALC49537.1    KA647023    AFP61652.1    CH933811    KRG07011.1    KRG07012.1    EDW06549.1    JRES01001682    KNC20991.1    ADMH02001234    ETN63552.1    SSX06609.1    SSX26956.1    APGK01036673    KB740941    KB632225    ENN77621.1    ERL90247.1    GECU01034749    JAS72957.1    LJIJ01000762    ODM94730.1    NEVH01002541    PNF42368.1    GECU01001871    JAT05836.1    GECU01026786    JAS80920.1    GEBQ01022806    JAT17171.1    GEBQ01032255    JAT07722.1    KK852996    KDR12694.1    GDRN01069569    JAI64023.1    GDKW01002943    JAI53652.1    KQ981940    KYN32733.1    GBGD01000346    JAC88543.1    GECU01010955    JAS96751.1    GDIQ01060891    JAN33846.1    GL888334    EGI62574.1    ADTU01020808    ADTU01020809    KQ979147    KYN22447.1    LBMM01002163    KMQ95196.1    GEFH01000970    JAP67611.1    GDIQ01252046    JAJ99678.1    GDIP01208520    JAJ14882.1    GDIP01185869    JAJ37533.1    GDIQ01252047    JAJ99677.1    GEBQ01011051    JAT28926.1    GFPF01013309    MAA24455.1    GEDV01012036    JAP76521.1    GFAC01001251    JAT97937.1    GEDV01004932    JAP83625.1    GL450467    EFN80951.1    GDIQ01194243    JAK57482.1    KQ982721    KYQ51650.1    GECZ01012946    JAS56823.1    GGLE01004888    MBY09014.1    GEDC01023355    GEDC01006906    JAS13943.1    JAS30392.1    CH480825    EDW43953.1    GL732611    EFX71325.1    GDIQ01194244    JAK57481.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000075901    UP000069272    UP000075881    + More
UP000075883    UP000075920    UP000075885    UP000075900    UP000030765    UP000075902    UP000076408    UP000076407    UP000007062    UP000075840    UP000002320    UP000075882    UP000075903    UP000075884    UP000075880    UP000069940    UP000249989    UP000183832    UP000192221    UP000075886    UP000002282    UP000007801    UP000008711    UP000000803    UP000268350    UP000008820    UP000092461    UP000001819    UP000007798    UP000008792    UP000092553    UP000095301    UP000009192    UP000037069    UP000000673    UP000019118    UP000030742    UP000091820    UP000095300    UP000094527    UP000235965    UP000002358    UP000027135    UP000078200    UP000078541    UP000007755    UP000005205    UP000078492    UP000036403    UP000008237    UP000075809    UP000001292    UP000000305   

PRIDE

H9JV06    X2JAB9    O46037    Q24584   

Pfam

PF01044   Vinculin

Interpro

IPR006077   Vinculin/catenin        + More
IPR036723   Alpha-catenin/vinculin-like_sf       
IPR017997   Vinculin       
IPR000633   Vinculin_CS       
IPR003323   OTU_dom       
IPR038765   Papain-like_cys_pep_sf       

SUPFAM

SSF47220   SSF47220        + More
SSF54001   SSF54001       

ProteinModelPortal

A0A2H1VC97   H9JV06   A0A3S2TTN0   A0A194PP83   A0A2M3Z6A1   A0A2M4A655   + More
A0A2M4BCB1   A0A182SU74   A0A182FG03   A0A182JNC5   A0A336MYC4   A0A336MF54   A0A182LRR4   A0A182WJ44   A0A182PQA9   A0A182RNF3   A0A084WNF9   A0A182U7M2   A0A182XZ03   A0A182X3L7   Q7QJI4   A0A182I3F2   B0X394   A0A182KRH3   A0A182VMB9   A0A023EWN7   A0A182NHR3   A0A182IJR2   A0A182HA48   A0A1J1HT91   A0A1W4VS88   A0A182Q5G7   B4Q189   B3MYS8   B3P8Y8   X2JAB9   O46037   A0A3B0JTC8   Q178I1   A0A1B0CGY0   Q29JL3   W8BFM7   Q24584   A0A1L8E3V2   B4NQ05   U5EZL2   A0A034VPM4   A0A0K8VFK9   A0A0Q9WIP8   A0A0A1XKI0   B4M7C8   A0A0M4FA38   T1PGN4   A0A0Q9XNY7   B4L5U0   A0A0L0BLR2   W5JGR3   A0A336M9K2   N6UAG2   A0A1A9WVM6   A0A1B6HE01   A0A1I8PZF7   A0A1D2MNR5   A0A2J7RNG9   A0A1B6K314   K7IMW4   A0A1B6I1Z1   A0A1B6L0M2   A0A1B6K8G4   A0A067QS50   A0A1A9UW50   A0A0P4WJ01   A0A0P4VGZ5   A0A195EWY0   A0A069DWV1   A0A1B6JBY8   A0A0P6ELG4   F4WTB1   A0A158NN08   A0A151JBF5   A0A0J7KY03   A0A131XPW9   A0A0P5FYW5   A0A0P4ZST5   A0A0P5BQX9   A0A0P5G2L4   A0A1B6LZ15   A0A224Z5F6   A0A131YF27   A0A1E1XF93   A0A131YYR8   E2BTN6   A0A0N8BBF2   A0A151WUQ8   A0A1B6G3E0   A0A2R5LHL7   A0A1B6CKP3   B4I9S2   E9HAB0   A0A0P5JWL5  

PDB

1ST6     E-value=5.17726e-72,     Score=689

KEGG

101736001    K05700 vinculin | (RefSeq) vinculin

GO

GO:0007155   GO:0051015   GO:0005198   GO:0015629   GO:0098592   GO:0005737   GO:0003779   GO:0005925   GO:0007016   GO:0016021   GO:0004965   GO:0005891   GO:0043565   GO:0003677   GO:0003707   GO:0006281   GO:0006259  

PANTHER

PTHR46180  

Subcellular location

Cytoplasm   Cytoplasmic face of adhesion plaques.   With evidence from 2 publications.
Cytoskeleton   Cytoplasmic face of adhesion plaques.   With evidence from 2 publications.
Cell junction   Cytoplasmic face of adhesion plaques.   With evidence from 2 publications.
Adherens junction   Cytoplasmic face of adhesion plaques.   With evidence from 2 publications.
Cell membrane   Cytoplasmic face of adhesion plaques.   With evidence from 2 publications.

Length:

440

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00018

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.01906

outside

1  -  440

 

 

Pi

248.261284

Theta

176.613374

Tajima's D

1.219595

CLR

0

CSRT

0.722713864306785

Interpretation

Uncertain