SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO15861
Pre Gene Modal
BGIBMGA013355
Annotation
PREDICTED:_potassium_voltage-gated_channel_protein_Shal_isoform_X3_[Amyelois_transitella]
Full name
Potassium voltage-gated channel protein Shal      
Alternative Name
Shaker cognate l
Shal2
Location in the cell
PlasmaMembrane   Reliability : 4.577
 

Sequence

CDS
ATGGCGTCCGTCGCCGCCTGGCTGCCCTTCGCCAGAGCAGCAGCCATCGGGTGGGTCCCCATCGCGACCCATCCACTTCCGCCGCCGCCCGTGCCCAAGGACCGCCGCCGTGCCGAGGACGAGAAGCTCCTCATCAACGTCTCCGGACGACGCTTTGAGACTTGGCGGAACACTCTCGAGAAGTACCCGGACTCGCTGCTTGGTTCCTCAGAACGCGAATTCTTTTACGACGAAGACAGCCGAGAGTACTTTTTTGACAGAGACCCGGACATATTCAGGCATATTCTGAATTATTACCGCACTGGTAAACTCCACTACCCCAAACACGAGTGCCTCACGGGCTACGATGAGGAACTCGCGTTCTTCGGCATCCTTCCCGATGTCATCGGTGACTGTTGTTACGAAGACTACAGAGACAGGAAGAGAGAAAATGCCGAACGTCTTATGGATGACAAGCTTAGTGAAGCAGGCGACCAGAGTCTGCCTCAGCTCACGGACTTACGACAAAAAATGTGGAGGGCCTTCGAGAACCCCCACACGTCAACGGCTGCCCTCGTGTTTTACTATGTGACTGGATTTTTCATTGCCGTCTCCGTGATGGCTAACGTAGTGGAGACGGTACCGTGCGGACACCGACCTGGCCGGGCCGGGACCCTGCCGTGCGGCGAACGCTACAAGATAGTGTTCTTCTGCCTGGACACGGCGTGCGTGATGATCTTCACGGCGGAGTACCTGCTGCGACTGTTCGCGGCCCCGGACCGCTGCAAGTTCGTTCGCTCGGTGATGTCCATCATCGACGTGGTCGCGATCCTGCCGTACTACATCGGCCTGGGTATCACTGACAACGACGACGTCTCGGGTGCGTTTGTCACCCTCAGAGTGTTCCGAGTGTTTCGGATCTTCAAGTTCTCGCGGCACTCCCAAGGACTAAGGATCCTGGGCTACACGCTCAAGTCGTGCGCCAGCGAGCTCGGCTTCCTGGTGTTCTCGCTCGCGATGGCCATCATTATATTCGCGACAGTGATGTTCTACGCGGAGAAGAACGAGCAGGACACAAACTTCACGTCGATTCCGGCCGCCTTCTGGTACACCATCGTCACGATGACCACGCTCGGGTAA
Protein
MASVAAWLPFARAAAIGWVPIATHPLPPPPVPKDRRRAEDEKLLINVSGRRFETWRNTLEKYPDSLLGSSEREFFYDEDSREYFFDRDPDIFRHILNYYRTGKLHYPKHECLTGYDEELAFFGILPDVIGDCCYEDYRDRKRENAERLMDDKLSEAGDQSLPQLTDLRQKMWRAFENPHTSTAALVFYYVTGFFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAILPYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEKNEQDTNFTSIPAAFWYTIVTMTTLG

Summary

Subunit
Heterotetramer of potassium channel proteins (By similarity). Interacts (via C-terminal dendritic targeting motif) with SIDL.
Miscellaneous
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
Similarity
Belongs to the potassium channel family.
Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Shal sub-subfamily.
Keywords
Alternative splicing   Cell projection   Complete proteome   Glycoprotein   Ion channel   Ion transport   Membrane   Potassium   Potassium channel   Potassium transport   Reference proteome   Transmembrane   Transmembrane helix   Transport   Voltage-gated channel  
Feature
chain  Potassium voltage-gated channel protein Shal
splice variant  In isoform A.
EMBL
KQ459597    KPI95229.1    AGBW02013760    OWR42869.1    KQ460466    KPJ14627.1    + More
NWSH01003471    PCG66226.1    ODYU01006515    SOQ48431.1    JTDY01001805    KOB72836.1    KK855317    PTY21967.1    ACPB03001681    ACPB03001682    GFXV01007813    MBW19618.1    MF359242    AWK26945.1    CH916366    EDV97990.1    GBXI01005809    JAD08483.1    GBXI01002680    JAD11612.1    GDHF01027171    GDHF01012288    GDHF01003580    JAI25143.1    JAI40026.1    JAI48734.1    GAKP01017790    GAKP01017788    GAKP01017786    JAC41164.1    CH933809    EDW18952.1    JRES01000778    KNC28395.1    CH940647    EDW69881.1    KRF84625.1    KRF84627.1    KRF84629.1    KRF84631.1    KRF84632.1    KRF84630.1    CCAG010017555    KRG06431.1    JXJN01008949    ABLF02039740    ABLF02039755    ABLF02039756    ABLF02044019    GBXI01006471    JAD07821.1    CH954178    KQS44245.1    KQS44246.1    M32660    AE014296    BT024203    KRF84626.1    KRG06430.1    AGB94748.1    CH902618    KPU78821.1    KQS44243.1    KQS44244.1    KRF84628.1    EDV40866.1    CH480844    EDW49795.1    EDV52378.1    GAMC01010327    GAMC01010326    GAMC01010323    JAB96229.1    NEVH01020852    PNF21151.1    KK853224    KDR09686.1    CH963876    EDW76785.1    CP012525    ALC44765.1    CH379070    KRT08970.1    DS235033    EEB10780.1    OUUW01000002    SPP76601.1    EAL30453.2    CH479227    EDW35321.1    KRT08971.1    KQ434977    KZC12902.1    KQ976542    KYM81130.1    KZ288291    PBC29202.1    KQ981965    KYN31665.1    JR040403    AEY59117.1    KQ979608    KYN20290.1    GFDF01009114    JAV04970.1    KQ977004    KYN06423.1    KQ982482    KYQ55835.1    KQ414617    KOC68214.1    JR040402    AEY59116.1    KQ435851    KOX70822.1    KQ778189    OAD52013.1    KQ971307    EFA10968.1    GBYB01013763    JAG83530.1    KK107144    EZA57610.1    QOIP01000003    RLU24320.1    ADTU01028805    GL764900    EFZ17091.1    APGK01047179    KB741077    KB632384    ENN74185.1    ERL94320.1    LJIG01022461    KRT80456.1    GL437497    EFN70370.1    LBMM01002395    KMQ94879.1    CM002912    KMZ00564.1    AXCN02000434    AAAB01008807    EAA03996.2    ADMH02000859    ETN64838.1    CH477421    EAT41230.1    ATLV01024081    KE525348    KFB50507.1    AXCM01007912   
Pfam
PF00520   Ion_trans        + More
PF02214   BTB_2
PF11601   Shal-type
PF11879   DUF3399
Interpro
IPR000210   BTB/POZ_dom        + More
IPR003968   K_chnl_volt-dep_Kv       
IPR011333   SKP1/BTB/POZ_sf       
IPR028325   VG_K_chnl       
IPR003975   K_chnl_volt-dep_Kv4       
IPR005821   Ion_trans_dom       
IPR027359   Volt_channel_dom_sf       
IPR003131   T1-type_BTB       
IPR021645   Shal-type_N       
IPR024587   K_chnl_volt-dep_Kv4_C       
SUPFAM
SSF54695   SSF54695       
Gene 3D
PDB
2I2R     E-value=1.70736e-58,     Score=572

Ontologies

Topology

Subcellular location
Membrane  
Cell projection  
Dendrite  
Perikaryon  
Length:
372
Number of predicted TMHs:
4
Exp number of AAs in TMHs:
96.77039
Exp number, first 60 AAs:
2.94086
Total prob of N-in:
0.64916
inside
1  -  184
TMhelix
185  -  207
outside
208  -  226
TMhelix
227  -  249
inside
250  -  260
TMhelix
261  -  280
outside
281  -  322
TMhelix
323  -  345
inside
346  -  372
 
 

Population Genetic Test Statistics

Pi
324.937729
Theta
237.440582
Tajima's D
1.133166
CLR
0
CSRT
0.696565171741413
Interpretation
Uncertain
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