SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO15846  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA000002
Annotation
PREDICTED:_uncharacterized_protein_LOC101745378_[Bombyx_mori]
Full name
MICOS complex subunit MIC60      
Alternative Name
Mitofilin
Location in the cell
Extracellular   Reliability : 1.064 Nuclear   Reliability : 1.388
 

Sequence

CDS
ATGATCAGAATAGCACAACATGGTGTCAATATTAGAACAATACTAGTATATGCAACTGGGACACGCCGGGATGATTTTATACTCAAGTATGATGTGCCGACTGACACTAATGACCGCCAGCAGCGCCGTCACAGACCCCTGCAACTACAAGGGTCGCACCTACATCAGTGTACCTCCTTGTACAAGTACATTGACCCCCGGGAACGACCTCCGTGTCCTCCGCCGCCCGTGCCGCCCCCTCCCGCGCCTCGGGACTACAAACTGTTCTGGGGAGCGATGACGGCCCTCGTGCTGGCGGGAGGCTTCGCTGCTTACGCCAAAACGTCCCCGGAGGTCAGAGATTGGCTGACGATCAACGCTCCCTGGTTCGATGACGTAATCGCCGTCGCGTACCAGGAGAACATGACCTACAAAGAGTTCATATTACAATGCACTGAAGACGCCAAGAAGTATTTGAATAGCTACGTCCGAGACGACAAGCCCAAGCAGTGCTCGTTTGAGGAGGGATCGGCGCTGTCTAATGTTGGTTAG
Protein
MIRIAQHGVNIRTILVYATGTRRDDFILKYDVPTDTNDRQQRRHRPLQLQGSHLHQCTSLYKYIDPRERPPCPPPPVPPPPAPRDYKLFWGAMTALVLAGGFAAYAKTSPEVRDWLTINAPWFDDVIAVAYQENMTYKEFILQCTEDAKKYLNSYVRDDKPKQCSFEEGSALSNVG

Summary

Description
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subunit
Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
Similarity
Belongs to the MICOS complex subunit Mic60 family.
Uniprot
Pfam
PF09731   Mitofilin
Interpro
IPR019133   Mt-IM_prot_Mitofilin       
ProteinModelPortal

Ontologies

Topology

Subcellular location
Mitochondrion inner membrane  
Length:
176
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
8.87908
Exp number, first 60 AAs:
0.02862
Total prob of N-in:
0.33232
outside
1  -  176
 
 

Population Genetic Test Statistics

Pi
291.703428
Theta
216.139498
Tajima's D
1.091018
CLR
0.002358
CSRT
0.685615719214039
Interpretation
Uncertain
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