SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO15796
Pre Gene Modal
BGIBMGA000034
Annotation
PREDICTED:_ADP-ribosylation_factor-like_protein_3_[Amyelois_transitella]
Full name
ADP-ribosylation factor-like protein 3      
Location in the cell
Nuclear   Reliability : 1.768
 

Sequence

CDS
ATGGGTCTGCTAGATATATTAAAGAAACTGCGATCTAATCCGGAGAAAGAGCTTCGTTTGCTGCTGTTAGGGCTGGACAATGCTGGAAAGACGACTCTATTGAAGCAATTGGCTTCGGAAGACGTGAACCACGTTATCCCGACCGCTGGTTTTAATATAAAATCGGTGTTATCGAATGGCTTCAAGCTAAATGTTTGGGATATCGGTGGACAGAGGAAGATCAGGCCTTATTGGAGGAATTATTTTGAGAACACCGATATTTTGATCTACGTGGTCGATTGTTCAGATCACCATAGACTGGAGGAGACCAGTCTAGAATTAGCCGAGCTGCTTCTGGATGACAAGTTGCGCGCTGTTCCGCTGTTAGTTTACGCCAACAAACAGGACTTGGCGACCGGTGCGTATAGATAA
Protein
MGLLDILKKLRSNPEKELRLLLLGLDNAGKTTLLKQLASEDVNHVIPTAGFNIKSVLSNGFKLNVWDIGGQRKIRPYWRNYFENTDILIYVVDCSDHHRLEETSLELAELLLDDKLRAVPLLVYANKQDLATGAYR

Summary

Description
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium (By similarity).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Keywords
Cell cycle   Cell division   Cell projection   Complete proteome   Cytoplasm   Cytoskeleton   Golgi apparatus   GTP-binding   Lipoprotein   Membrane   Myristate   Nucleotide-binding   Nucleus   Protein transport   Reference proteome   Transport  
Feature
chain  ADP-ribosylation factor-like protein 3
EMBL
BABH01035561    KZ150146    PZC72890.1    NWSH01001860    PCG69884.1    ODYU01001334    + More
SOQ37373.1    KQ459144    KPJ03653.1    QUSF01000019    RLW02261.1    MUZQ01000028    OWK62302.1    DQ214094    DQ214098    LSYS01003057    OPJ84270.1    AGTO01020393    KB744554    EOA94851.1    PYGN01000005    PSN58282.1    AADN05000306    KK476187    KFQ59059.1    KL447725    KFO76618.1    AF467986    BC087495    CM004479    OCT70000.1    AHAT01023146    AHAT01023147    JW877282    AFP09799.1    ADON01131571    DS235806    EEB17320.1    KL506294    KFO84964.1    BC164965    AAI64965.1    AL928692    BC124704    GBYX01185110    GBYX01185107    JAO84674.1    IACN01036013    LAB51428.1    HAED01005725    HAEE01014524    SBR34574.1    HADZ01001558    HAEA01013164    SBQ41644.1    HAEB01016601    HAEC01003806    SBQ71883.1    HADY01019192    HAEJ01012491    SBP57677.1    KQ971372    EFA10265.2    HAEG01011268    SBR89300.1    KK835030    KFP79387.1    KL669486    KFW76472.1    KL217222    KFV74665.1    KK718105    KFO54381.1    ABQF01027016    HAEI01001129    SBR74813.1    KL390015    KFP91309.1    HAEH01017247    SBS05818.1    KK546302    KFP32439.1    KL886967    KGL74345.1    KK408916    KFQ83548.1    KL217736    KFO98267.1    KK744307    KFP39722.1    KK387638    KFV52221.1    KL205881    KFV76044.1    KL226002    KFM06576.1    KK528189    KFP68894.1    KK857188    PTY26926.1    JT409914    AHH38872.1    JTDY01005255    KOB67191.1    GECZ01009374    JAS60395.1    KK595622    KFW02998.1    KK626404    KFV53528.1    KL409842    KFQ92217.1    KL427788    KFW90754.1    KK733873    KFR00868.1    KL484601    KFO09187.1    KK501486    KFP15314.1   
Pfam
PF00025   Arf
Interpro
IPR006689   Small_GTPase_ARF/SAR        + More
IPR005225   Small_GTP-bd_dom       
IPR027417   P-loop_NTPase       
SUPFAM
SSF52540   SSF52540       
PDB
4ZI3     E-value=2.01065e-43,     Score=435

Ontologies

Topology

Subcellular location
Golgi apparatus membrane   Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).   With evidence from 1 publications.
Cytoplasm   Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).   With evidence from 1 publications.
Cytoskeleton   Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).   With evidence from 1 publications.
Spindle   Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).   With evidence from 1 publications.
Nucleus   Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).   With evidence from 1 publications.
Microtubule organizing center   Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).   With evidence from 1 publications.
Centrosome   Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).   With evidence from 1 publications.
Cell projection   Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).   With evidence from 1 publications.
Cilium   Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle (By similarity).   With evidence from 1 publications.
Length:
136
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.00675
Exp number, first 60 AAs:
0.00511
Total prob of N-in:
0.04773
outside
1  -  136
 
 

Population Genetic Test Statistics

Pi
21.368553
Theta
27.491573
Tajima's D
-0.701684
CLR
0.029614
CSRT
0.193790310484476
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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