Gene

KWMTBOMO15779

Pre Gene Modal

BGIBMGA002345

Annotation

PREDICTED:_zinc_transporter_ZIP13_homolog_[Papilio_xuthus]

Location

Bomo_Chr26(+):9788447-9815857      View in EpiBrowser

Full name

Zinc transporter ZIP13 homolog       + More
Mediator of RNA polymerase II transcription subunit 15      

Alternative Name

Zinc/iron regulated transporter-related protein 99C
Mediator complex subunit 15

Location in the cell

PlasmaMembrane   Reliability : 3.116

CDS

ATGGCGAGCTACGTGCCAGAATATTTGTCCAATTTTGTGGAAGAATTAGATGAACATCCGTGGATTTTCGCTTCGCTGGCGTCGATGCTGGTCGGTTTAAGCGGCATCTTACCGCTGTTCATCATTCCACTGGATTCTTCAGCCACATTCGAAGATGGGCCCGGGGCAGCCACACTTCGGATCCTGCTCAGTTTCGCTGTAGGCGGTCTACTGGGCGATGTCTTCCTCCACCTACTACCGGAAGCGTGGGAAAATGATATGGCCAACACTAAAGCGGGACAACACGTTTCTCTCAAGAGCGGTCTGTGGTGTCTGTTCGGTATGCTGGTCTTCATAGTCGTGGAGAAGCTGTTCTCGGTGGACGAGCACAACGACGGCGAAGAGGAGGAGGAGAAGCAGAACGGCGCAATAAAGCAGATAGAGATCGAAGAGATCGAGAAACTGCTCGAGATCGAAAGGAAACATCGGGGAGTGGATAAGGGGATCTGCAATGGAACGGTGACCGCCAAGCAGATATACGATTCTTGTATCTTCAATAATAACACTAAAGGCGAAGGAGGATGTTGCAGTATGCCTACAAGCAACGCTGGAGCCAGCGGCCGCTGTAAGGGCTCCTCTCGCTGGATGGGGCGCTGCTTGCTTCGGGAAGCTCGCGAGAAAGCACTCCGCGCCAGTAAAGAGAAAACTGAGAAGAAAGATGTGGCGGGCTATTTGAATCTGATGGCGAACTCGATCGACAACTTCACCCACGGACTCGCGGTCGGGGGCTCGTTCCTCGTCGGGTTCCGGGTCGGAGTTCTCACCACCTTTGCCATATTAGTGCACGAGATCCCGCACGAGGTGGGAGACTTCGCCATACTGCTGAAGAGCGGGTTCTCCAGGTGGGAGGCCGCCAAAGCACAACTGGCCACGGCGACGGCGGGGCTGGTGGGCGCCATGACGGCCGTCGTGTTCAGCGGCGCCAGCAATTCGCTCGAAGCGAAGACCTCGTGGATCGTGCCGTTCACGGCGGGCGGGTTCCTGCACATCGCGCTGGTGACGGTGCTGCCGGACCTGCTGCGGGAGCACTCCAAGCTGGAGTCCCTAAAGCACTTCGCGGCGCTCGCCCTCGGCATCCTGCTCATGCACACCCTCACCACAGTTCATAGAGAGATGTAA

Protein

MASYVPEYLSNFVEELDEHPWIFASLASMLVGLSGILPLFIIPLDSSATFEDGPGAATLRILLSFAVGGLLGDVFLHLLPEAWENDMANTKAGQHVSLKSGLWCLFGMLVFIVVEKLFSVDEHNDGEEEEEKQNGAIKQIEIEEIEKLLEIERKHRGVDKGICNGTVTAKQIYDSCIFNNNTKGEGGCCSMPTSNAGASGRCKGSSRWMGRCLLREAREKALRASKEKTEKKDVAGYLNLMANSIDNFTHGLAVGGSFLVGFRVGVLTTFAILVHEIPHEVGDFAILLKSGFSRWEAAKAQLATATAGLVGAMTAVVFSGASNSLEAKTSWIVPFTAGGFLHIALVTVLPDLLREHSKLESLKHFAALALGILLMHTLTTVHREM

Description

Involved in zinc transport and homeostasis.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subunit

Component of the Mediator complex.

Similarity

Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
Belongs to the Mediator complex subunit 15 family.

Keywords

Cell membrane   Complete proteome   Glycoprotein   Golgi apparatus   Ion transport   Membrane   Reference proteome   Transmembrane   Transmembrane helix   Transport   Zinc   Zinc transport  

Feature

chain  Zinc transporter ZIP13 homolog

Uniprot

H9IYL1   A0A0N1PFS4   A0A194QDW8   A0A2W1BK27   A0A212ERG0   A0A1A9W7Y1   + More
A0A0A1WY74   A0A0A1XNR0   A0A0M5JCT1   A0A0K8TLC1   B4R0U7   B4HZG9   B3LYT7   A4V3L8   Q9VAF0   B4NK13   A0A034WJV5   A0A1B0AYC9   D3TSB2   A0A0L0C7J4   B4M5R5   A0A1W4URN3   B4PPI2   B4K5Z6   A0A0K8W0P3   A0A3B0JFR1   A0A0K8VS14   B4JYL0   B4GNJ6   Q29C60   D0QWQ1   B3P5B3   A0A0R3NF67   A0A1A9Z8A5   Q16FG6   A0A1A9XI93   A0A1A9V3F4   W8BM22   A0A2M4AGL3   A0A2M4AIJ7   A0A2M3ZB96   A0A1L8DEG1   A0A1L8DEH9   A0A1L8DE02   U5EX14   W5JIU1   A0A1J1IVX9   K7IR27   A0A182MM77   A0A1B0CR50   A0A1I8NNW4   A0A336LUY9   A0A232F907   A0A1L8EDW2   T1PKA0   A0A182KDQ8   A0A1L8DDI0   A0A1B6E318   A0A1Q3G3M6   A0A182RHY3   A0A182FNG5   A0A2M4BP99   A0A2M4BQ56   A0A1B6J1S2   A0A1B0FB02   T1DTA1   A0A182VQL6   A0A182P5R3   A0A182QC95   A0A182V8M6   A0A182IIW3   A0A1B6FC85   A0A182JAY0   A0A182LCR9   Q7PLY3   A0A2S2PTK2   A0A182NL67   A0A023ENP7   A0A1B0DEG7   A0A195B1U7   A0A2H8TYI2   A0A182X1Z0   A0A1L8E8X5   A0A151JQA1   A0A1Q3FF19   A0A2J7PUE6   A0A1S3IPE5   A0A182TLS0   A0A3M6U720   C3Y490   A0A3B3R623   A0A3Q1G139   A0A3Q3KWJ0   A0A3Q3R3B1   A0A3B4TYZ5   A0A3P8ZTA2   A0A3Q3KK36   A0A3B4YCT0   A0A3Q1HZQ2  

Pubmed

19121390    26354079    28756777    22118469    25830018    26369729    + More
17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    12537569    23322169    25348373    20353571    26108605    18057021    17550304    15632085    23185243    19859648    17510324    24495485    20920257    23761445    20075255    28648823    25315136    20966253    12364791    14747013    17210077    24945155    30382153    18563158    29240929    25069045   

EMBL

BABH01020899    KQ461188    KPJ07322.1    KQ459193    KPJ03145.1    KZ150129    + More
PZC73080.1    AGBW02013027    OWR44067.1    GBXI01014723    GBXI01010964    JAC99568.1    JAD03328.1    GBXI01014111    GBXI01010992    GBXI01001328    JAD00181.1    JAD03300.1    JAD12964.1    CP012526    ALC47168.1    GDAI01002888    JAI14715.1    CM000364    EDX14918.1    CH480819    EDW53426.1    CH902617    EDV44053.1    AE014297    AAN14196.1    AAN14197.1    AAN14198.1    AAN14199.1    ADV37403.1    ADV37404.1    ADV37405.1    BT001774    CH964272    EDW84015.1    GAKP01004001    GAKP01004000    GAKP01003999    GAKP01003998    JAC54954.1    JXJN01005666    JXJN01005667    JXJN01005668    EZ424314    ADD20590.1    JRES01000809    KNC28221.1    CH940652    EDW58991.1    KRF78632.1    CM000160    EDW98232.1    KRK04169.1    CH933806    EDW16233.1    GDHF01016177    GDHF01007648    JAI36137.1    JAI44666.1    OUUW01000005    SPP80965.1    GDHF01010964    JAI41350.1    CH916377    EDV90772.1    CH479186    EDW39322.1    CM000070    EAL26786.1    EIM52297.1    KRS99548.1    KRS99549.1    FJ821034    ACN94762.1    CH954182    EDV53163.1    KRS99547.1    CH478442    EAT32983.1    GAMC01012136    GAMC01012134    JAB94421.1    GGFK01006595    MBW39916.1    GGFK01007294    MBW40615.1    GGFM01005020    MBW25771.1    GFDF01009232    JAV04852.1    GFDF01009233    JAV04851.1    GFDF01009540    JAV04544.1    GANO01000295    JAB59576.1    ADMH02001124    ETN64041.1    CVRI01000058    CRL02697.1    AXCM01004511    AJWK01024397    UFQT01000202    SSX21660.1    NNAY01000669    OXU27082.1    GFDG01002020    JAV16779.1    KA649190    KA649191    AFP63820.1    GFDF01009555    JAV04529.1    GEDC01005011    JAS32287.1    GFDL01000679    JAV34366.1    GGFJ01005756    MBW54897.1    GGFJ01005757    MBW54898.1    GECU01014600    GECU01014553    JAS93106.1    JAS93153.1    CCAG010023703    GAMD01001094    JAB00497.1    AXCN02000083    APCN01002160    GECZ01022206    GECZ01006067    JAS47563.1    JAS63702.1    AAAB01008982    EAA14648.3    GGMR01020088    MBY32707.1    GAPW01003038    JAC10560.1    AJVK01032733    AJVK01032734    AJVK01032735    KQ976667    KYM78260.1    GFXV01007046    MBW18851.1    GFDG01003767    JAV15032.1    KQ978700    KYN29147.1    GFDL01008906    JAV26139.1    NEVH01021199    PNF19953.1    RCHS01002149    RMX49339.1    GG666484    EEN65116.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000091820    UP000092553    + More
UP000000304    UP000001292    UP000007801    UP000000803    UP000007798    UP000092460    UP000037069    UP000008792    UP000192221    UP000002282    UP000009192    UP000268350    UP000001070    UP000008744    UP000001819    UP000008711    UP000092445    UP000008820    UP000092443    UP000078200    UP000000673    UP000183832    UP000002358    UP000075883    UP000092461    UP000095300    UP000215335    UP000095301    UP000075881    UP000075900    UP000069272    UP000092444    UP000075920    UP000075885    UP000075886    UP000075903    UP000075840    UP000075880    UP000075882    UP000007062    UP000075884    UP000092462    UP000078540    UP000076407    UP000078492    UP000235965    UP000085678    UP000075902    UP000275408    UP000001554    UP000261540    UP000257200    UP000261640    UP000261600    UP000261420    UP000265140    UP000261360    UP000265040   

PRIDE

H9IYL1    A4V3L8    Q9VAF0   

Pfam

PF02535   Zip        + More
PF09606   Med15
PF04592   SelP_N

Interpro

IPR003689   ZIP        + More
IPR019087   Med15       
IPR007671   Selenoprotein-P_N       
IPR037941   SeP       

ProteinModelPortal

H9IYL1   A0A0N1PFS4   A0A194QDW8   A0A2W1BK27   A0A212ERG0   A0A1A9W7Y1   + More
A0A0A1WY74   A0A0A1XNR0   A0A0M5JCT1   A0A0K8TLC1   B4R0U7   B4HZG9   B3LYT7   A4V3L8   Q9VAF0   B4NK13   A0A034WJV5   A0A1B0AYC9   D3TSB2   A0A0L0C7J4   B4M5R5   A0A1W4URN3   B4PPI2   B4K5Z6   A0A0K8W0P3   A0A3B0JFR1   A0A0K8VS14   B4JYL0   B4GNJ6   Q29C60   D0QWQ1   B3P5B3   A0A0R3NF67   A0A1A9Z8A5   Q16FG6   A0A1A9XI93   A0A1A9V3F4   W8BM22   A0A2M4AGL3   A0A2M4AIJ7   A0A2M3ZB96   A0A1L8DEG1   A0A1L8DEH9   A0A1L8DE02   U5EX14   W5JIU1   A0A1J1IVX9   K7IR27   A0A182MM77   A0A1B0CR50   A0A1I8NNW4   A0A336LUY9   A0A232F907   A0A1L8EDW2   T1PKA0   A0A182KDQ8   A0A1L8DDI0   A0A1B6E318   A0A1Q3G3M6   A0A182RHY3   A0A182FNG5   A0A2M4BP99   A0A2M4BQ56   A0A1B6J1S2   A0A1B0FB02   T1DTA1   A0A182VQL6   A0A182P5R3   A0A182QC95   A0A182V8M6   A0A182IIW3   A0A1B6FC85   A0A182JAY0   A0A182LCR9   Q7PLY3   A0A2S2PTK2   A0A182NL67   A0A023ENP7   A0A1B0DEG7   A0A195B1U7   A0A2H8TYI2   A0A182X1Z0   A0A1L8E8X5   A0A151JQA1   A0A1Q3FF19   A0A2J7PUE6   A0A1S3IPE5   A0A182TLS0   A0A3M6U720   C3Y490   A0A3B3R623   A0A3Q1G139   A0A3Q3KWJ0   A0A3Q3R3B1   A0A3B4TYZ5   A0A3P8ZTA2   A0A3Q3KK36   A0A3B4YCT0   A0A3Q1HZQ2  

KEGG

101742524    K14719 solute carrier family 39 (zinc transporter), member 13 | (RefSeq) zinc transporter ZIP13 homo

GO

GO:0046873   GO:0016021   GO:0016323   GO:0005794   GO:0010312   GO:0060586   GO:0005381   GO:0005783   GO:0005385   GO:0006826   GO:0000139   GO:0016592   GO:0006357   GO:0003712   GO:0008430   GO:0005623   GO:0006882   GO:0071577   GO:0016020   GO:0030001   GO:0008270   GO:0005215   GO:0006270   GO:0042555   GO:0003707   GO:0006281   GO:0006259   GO:0055085  

PANTHER

PTHR10105  

Subcellular location

Basolateral cell membrane  
Golgi apparatus membrane  
Nucleus  

Length:

385

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

140.16663

Exp number, first 60 AAs:

26.48587

Total prob of N-in:

0.41503

POSSIBLE N-term signal

sequence

inside

1  -  19

TMhelix

20  -  42

outside

43  -  56

TMhelix

57  -  79

inside

80  -  251

TMhelix

252  -  274

outside

275  -  301

TMhelix

302  -  324

inside

325  -  330

TMhelix

331  -  350

outside

351  -  364

TMhelix

365  -  382

inside

383  -  385

 

 

Pi

208.967335

Theta

171.082969

Tajima's D

-1.966376

CLR

0.420277

CSRT

0.0180490975451227

Interpretation

Possibly Positive selection