Gene

KWMTBOMO15763  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002239

Annotation

PREDICTED:_probable_sodium/potassium/calcium_exchanger_CG1090_[Bombyx_mori]

Location

Bomo_Chr26(-):9531129-9534567      View in EpiBrowser

Full name

Probable sodium/potassium/calcium exchanger CG1090      

Alternative Name

Na(+)/K(+)/Ca(2+)-exchange protein CG1090

Location in the cell

PlasmaMembrane   Reliability : 4.848

CDS

ATGGGTCAAAAAGCTCGAAAGCACGGCGGCCTGATCCTGCACATACTGGTCGCCATGTTCACGTTCATAGGACTCGCTATCGTGTGCGACGAGTACTTCGTGTCAAGCTTGGACAGGATCTGTGAAGAACTGAGGTTGGCGCCCGATGTTGCTGGAGCGACGTTCATGGCGGCGGGTAGTTCCGCTCCTGAGCTGGCGACCGTCGTCATCGGCGTCTTCTGCGCTCAGGATGACATAGGCGTCTCGGGTGTGATCGGTTCGGCGGTATTCAACATTATGTTCGTGATATCCGTGTGTGCCCTCTGCGCCGGCACCGTGTCGCATCTCAACTGGTGGCCCCTCTGCAGAGACTGCTTCTTCTACGCCCTATCTATACTGGTGATGCTGTGTACCATCGCTAATGAATACGTTAGCTGGCCTGAAGCTCTGTTCATGTTGATAATGTACGGAGTGTACTGCGTGGCGCTTCGGTTCAACACGGCGCTGGAGCAATGGGCGATGACTCTCCCTCTGCCCTTCAAACTGCCGACCAGGGAGGAGCAGGCGGCCCTTGTAACCTACAGCCGGAATGCCGCGGCGGGCCCGACTCCGGCCGCGGAGGGCCAGTACTCGCAAGTCGACGGACGCACCAACGACACTCCGGTTCAAGAAACATGTAACGATATTAAACAAACTCAATTACGATTATACTTAATTAAAACTACTCATACGGTTTAA

Protein

MGQKARKHGGLILHILVAMFTFIGLAIVCDEYFVSSLDRICEELRLAPDVAGATFMAAGSSAPELATVVIGVFCAQDDIGVSGVIGSAVFNIMFVISVCALCAGTVSHLNWWPLCRDCFFYALSILVMLCTIANEYVSWPEALFMLIMYGVYCVALRFNTALEQWAMTLPLPFKLPTREEQAALVTYSRNAAAGPTPAAEGQYSQVDGRTNDTPVQETCNDIKQTQLRLYLIKTTHTV

Description

May function in the removal and maintenance of calcium homeostasis. Transports one Ca(2+) and 1 K(+) in exchange for 4 Na(+) (By similarity).

Similarity

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.

Keywords

Antiport   Calcium   Calcium transport   Complete proteome   Ion transport   Membrane   Potassium   Potassium transport   Reference proteome   Repeat   RNA editing   Signal   Sodium   Sodium transport   Symport   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Probable sodium/potassium/calcium exchanger CG1090

Uniprot

H9IYA6   A0A2H1WKQ5   A0A2A4IZH9   A0A0N0PB80   A0A194QF84   A0A2P8YU81   + More
A0A1B0D898   A0A154PLE5   A0A336KNY8   E9J749   A0A088ACR0   A0A0L7RHF3   E2B4C0   A0A1B6E0V6   V9IA28   A0A026WB44   A0A034W580   A0A3L8DQE3   A0A084VB85   A0A310SFR1   A0A182PHV9   B0WL45   A0A182V9E6   A0A182Y8Q7   A0A182XIG7   A0A182KZH1   Q7PQ73   A0A1S4G2H8   A0A182U261   A0A182HYR2   Q16G46   A0A182W3I1   A0A182N9X8   A0A182SVU9   A0A0K8TXV9   W5JVN3   E2AM73   A0A151X900   A0A2M4CGF8   K7J6I2   W8B819   A0A182LZG0   A0A182QSK2   A0A151IAK1   A0A182RE22   A0A158NDL1   A0A151HZT2   A0A0A1WDU9   A0A182K7D9   A0A2J7RFW1   A0A195F3B2   A0A0J7KX36   A0A0N0BDA0   A0A1I8NZT1   A0A1W4VLH9   B3P1Z6   A0A0C9R918   E0VUZ2   A0A0B4KGG6   Q9VN12   A0A0C9RVE0   B4I3M8   B3LY08   A0A1I8M2L9   A0A0M4ENA3   A0A0R1E4I6   B4QV08   D6X2J2   B4NIE0   B4MC24   A0A182FAM0   B4PTR4   A0A0R1E2Y4   B4K6W7   A0A0L0CGN2   B4JGF5   A0A139WB83   B4GM46   A0A3B0K4Q8   A0A3B0K6I3   A0A1J1II27   B5DVN3   A0A1A9WY23   A0A1B0G9C3   A0A1A9Z9K9   A0A1A9UJR7   A0A1A9XG37   A0A1B0BEG6   U4UH28   N6TY53   A0A1B6IXN5   A0A151J3L5   F4W9A0   T1I485   A0A224XLU0   A0A2S2R0U6   A0A2S2R958   A0A2H8TDR9  

Pubmed

19121390    26354079    29403074    21282665    20798317    24508170    + More
25348373    30249741    24438588    25244985    20966253    12364791    14747013    17210077    17510324    20920257    23761445    20075255    24495485    21347285    25830018    17994087    20566863    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    17018572    25315136    17550304    18362917    19820115    18057021    26108605    15632085    23537049    21719571   

EMBL

BABH01020876    BABH01020877    ODYU01009325    SOQ53665.1    NWSH01004323    PCG65225.1    + More
KQ461111    KPJ08939.1    KQ459144    KPJ03605.1    PYGN01000356    PSN47796.1    AJVK01004004    KQ434960    KZC12689.1    UFQS01000650    UFQT01000650    SSX05758.1    SSX26117.1    GL768421    EFZ11371.1    KQ414590    KOC70397.1    GL445549    EFN89468.1    GEDC01005781    JAS31517.1    JR036456    JR036457    JR036458    AEY57157.1    AEY57158.1    AEY57159.1    KK107293    EZA53280.1    GAKP01009485    JAC49467.1    QOIP01000005    RLU22496.1    ATLV01006066    KE524335    KFB35229.1    KQ760478    OAD60235.1    DS231979    EDS30208.1    AAAB01008898    EAA09212.5    APCN01005401    CH478335    EAT33209.1    GDHF01033037    JAI19277.1    ADMH02000289    ETN67110.1    GL440715    EFN65479.1    KQ982402    KYQ56843.1    GGFL01000063    MBW64241.1    GAMC01011793    JAB94762.1    AXCM01000353    AXCN02001605    KQ978223    KYM96270.1    ADTU01001044    ADTU01001045    KQ976664    KYM78300.1    GBXI01017461    JAC96830.1    NEVH01004410    PNF39724.1    KQ981855    KYN34871.1    LBMM01002249    KMQ95077.1    KQ435876    KOX70134.1    CH954181    EDV47769.1    GBYB01012864    JAG82631.1    DS235797    EEB17198.1    AE014297    AGB95635.1    AY094726    AAM11079.1    AAN13306.4    GBYB01012865    JAG82632.1    CH480821    EDW54821.1    CH902617    EDV42864.2    CP012526    ALC46126.1    CM000160    KRK02593.1    KRK02594.1    CM000364    EDX11589.1    KQ971372    EFA09437.2    CH964272    EDW83722.2    CH940656    EDW58645.2    KRF78377.1    KRF78378.1    EDW95647.2    KRK02595.1    CH933806    EDW15254.2    JRES01000409    KNC31578.1    CH916369    EDV92624.1    KYB25176.1    CH479185    EDW37920.1    OUUW01000014    SPP88283.1    SPP88282.1    CVRI01000047    CRK98105.1    CM000070    EDY68441.2    CCAG010016995    JXJN01012895    JXJN01012896    KB632294    ERL91668.1    APGK01050286    KB741169    ENN73311.1    GECU01016008    JAS91698.1    KQ980275    KYN17024.1    GL888002    EGI69282.1    ACPB03018838    GFTR01007026    JAW09400.1    GGMS01014444    MBY83647.1    GGMS01017290    MBY86493.1    GFXV01000434    MBW12239.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000245037    UP000092462    + More
UP000076502    UP000005203    UP000053825    UP000008237    UP000053097    UP000279307    UP000030765    UP000075885    UP000002320    UP000075903    UP000076408    UP000076407    UP000075882    UP000007062    UP000075902    UP000075840    UP000008820    UP000075920    UP000075884    UP000075901    UP000000673    UP000000311    UP000075809    UP000002358    UP000075883    UP000075886    UP000078542    UP000075900    UP000005205    UP000078540    UP000075881    UP000235965    UP000078541    UP000036403    UP000053105    UP000095300    UP000192221    UP000008711    UP000009046    UP000000803    UP000001292    UP000007801    UP000095301    UP000092553    UP000002282    UP000000304    UP000007266    UP000007798    UP000008792    UP000069272    UP000009192    UP000037069    UP000001070    UP000008744    UP000268350    UP000183832    UP000001819    UP000091820    UP000092444    UP000092445    UP000078200    UP000092443    UP000092460    UP000030742    UP000019118    UP000078492    UP000007755    UP000015103   

PRIDE

H9IYA6    Q9VN12   

Pfam

PF01699   Na_Ca_ex        + More
PF03820   Mtc
PF00307   CH

Interpro

IPR004837   NaCa_Exmemb        + More
IPR004481   K/Na/Ca-exchanger       
IPR004686   Mtc       
IPR036872   CH_dom_sf       
IPR001715   CH-domain       

SUPFAM

SSF47576   SSF47576       

Gene 3D

1.10.418.10    

ProteinModelPortal

H9IYA6   A0A2H1WKQ5   A0A2A4IZH9   A0A0N0PB80   A0A194QF84   A0A2P8YU81   + More
A0A1B0D898   A0A154PLE5   A0A336KNY8   E9J749   A0A088ACR0   A0A0L7RHF3   E2B4C0   A0A1B6E0V6   V9IA28   A0A026WB44   A0A034W580   A0A3L8DQE3   A0A084VB85   A0A310SFR1   A0A182PHV9   B0WL45   A0A182V9E6   A0A182Y8Q7   A0A182XIG7   A0A182KZH1   Q7PQ73   A0A1S4G2H8   A0A182U261   A0A182HYR2   Q16G46   A0A182W3I1   A0A182N9X8   A0A182SVU9   A0A0K8TXV9   W5JVN3   E2AM73   A0A151X900   A0A2M4CGF8   K7J6I2   W8B819   A0A182LZG0   A0A182QSK2   A0A151IAK1   A0A182RE22   A0A158NDL1   A0A151HZT2   A0A0A1WDU9   A0A182K7D9   A0A2J7RFW1   A0A195F3B2   A0A0J7KX36   A0A0N0BDA0   A0A1I8NZT1   A0A1W4VLH9   B3P1Z6   A0A0C9R918   E0VUZ2   A0A0B4KGG6   Q9VN12   A0A0C9RVE0   B4I3M8   B3LY08   A0A1I8M2L9   A0A0M4ENA3   A0A0R1E4I6   B4QV08   D6X2J2   B4NIE0   B4MC24   A0A182FAM0   B4PTR4   A0A0R1E2Y4   B4K6W7   A0A0L0CGN2   B4JGF5   A0A139WB83   B4GM46   A0A3B0K4Q8   A0A3B0K6I3   A0A1J1II27   B5DVN3   A0A1A9WY23   A0A1B0G9C3   A0A1A9Z9K9   A0A1A9UJR7   A0A1A9XG37   A0A1B0BEG6   U4UH28   N6TY53   A0A1B6IXN5   A0A151J3L5   F4W9A0   T1I485   A0A224XLU0   A0A2S2R0U6   A0A2S2R958   A0A2H8TDR9  

PDB

3V5U     E-value=3.43316e-06,     Score=119

KEGG

101735406    no KO assigned | (RefSeq) probable sodium/potassium/calcium exchanger CG1090

GO

GO:0055085   GO:0016021   GO:0005887   GO:0005262   GO:0006874   GO:0008273   GO:0070588   GO:0006814   GO:0006816   GO:0015293   GO:0015075   GO:0005524   GO:0006468   GO:0008270   GO:0005215   GO:0006270   GO:0042555   GO:0003707   GO:0006281   GO:0006259  

PANTHER

PTHR10846  

Subcellular location

Membrane  

Length:

238

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

87.7829300000001

Exp number, first 60 AAs:

24.89482

Total prob of N-in:

0.90053

POSSIBLE N-term signal

sequence

inside

1  -  8

TMhelix

9  -  28

outside

29  -  88

TMhelix

89  -  111

inside

112  -  117

TMhelix

118  -  137

outside

138  -  141

TMhelix

142  -  159

inside

160  -  238

 

 

Pi

139.714588

Theta

127.023899

Tajima's D

0.030218

CLR

0.000003

CSRT

0.379931003449827

Interpretation

Uncertain