Gene

KWMTBOMO15762  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002239

Annotation

PREDICTED:_probable_sodium/potassium/calcium_exchanger_CG1090_[Bombyx_mori]

Location

Bomo_Chr26(-):9524852-9529517      View in EpiBrowser

Full name

Probable sodium/potassium/calcium exchanger CG1090      

Alternative Name

Na(+)/K(+)/Ca(2+)-exchange protein CG1090

Location in the cell

PlasmaMembrane   Reliability : 3.801

CDS

ATGTATGTACACAAACAGAGTCAGAGCTACGACCCTCCGTCAGCGCGACTTGAACAGCCTCAGACCGCGAGCCCCCAACAGTCGCAACCGCAGCAAACGCAGCAACAGGCCCCGCCGCCACAAGCACCGGCGGCTCCCGCTTACTACAAGGCAAAGGAGTACAATCCCGAGACAGCCGTGGATCCTCTGGTCAAGCCGATCGGAGCCAATAAATTCCAATTGGCTTGCTGGTACATTGCGTTCCCGGTTCACTGGTCGTGTCGGCACACGATGCCTGACTGCCGGGGACCCTGGTACCCGGTCACCTTCATCATATCGATGCTCTGGATCTCGTTCTACTCCTACTTCATGGTCTGGATGATAACGATTATCGGCTATACACTCGGGATCCCGGACACGGTCATGGGTCTCACGTTTGTGGCGGCTGGAGTCTCTGTACCCGACGCGCTCTCCTCGCTCGCCGTCATCAAAGAAGGTTACGGAGACATGGCGGTGTCGAATGCCGTCGGCTCGAACGTCTTCGACATCCTGGTTTGCCTGGGACTGCCGTGGTTCCTGCAGACCGCCGTCATCCACCCCGGGAGCCATGTGAACGTTTACAGCAAAGGTCTGATCTATTCCACGTTATCGCTGTTTTCGACCGTCGTGTTTCTGGTGGTGGCTACCCACGCCAACGGCTGGAAGCTGGACCGGAAGTACGGCGCAGTGCTGATGGTCTGGTACGTTCTCTTCATAACACTGGCGAGCCTATACGAGCTGAACATCTTCGGGGAATACAACAAGCCGGATTGTATTTCGAAATATTAA

Protein

MYVHKQSQSYDPPSARLEQPQTASPQQSQPQQTQQQAPPPQAPAAPAYYKAKEYNPETAVDPLVKPIGANKFQLACWYIAFPVHWSCRHTMPDCRGPWYPVTFIISMLWISFYSYFMVWMITIIGYTLGIPDTVMGLTFVAAGVSVPDALSSLAVIKEGYGDMAVSNAVGSNVFDILVCLGLPWFLQTAVIHPGSHVNVYSKGLIYSTLSLFSTVVFLVVATHANGWKLDRKYGAVLMVWYVLFITLASLYELNIFGEYNKPDCISKY

Description

May function in the removal and maintenance of calcium homeostasis. Transports one Ca(2+) and 1 K(+) in exchange for 4 Na(+) (By similarity).

Similarity

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.

Keywords

Antiport   Calcium   Calcium transport   Complete proteome   Ion transport   Membrane   Potassium   Potassium transport   Reference proteome   Repeat   RNA editing   Signal   Sodium   Sodium transport   Symport   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Probable sodium/potassium/calcium exchanger CG1090

Uniprot

H9IYA6   A0A2A4IZH9   A0A194QF84   A0A0N0PB80   A0A1Y1MBJ7   A0A0C9RVE0   + More
A0A0C9R918   A0A1B6I5M1   E2B4C0   D6X2J2   E9J749   A0A139WB83   A0A1B6H4H0   A0A1S4G2H8   Q16G46   A0A154PLE5   A0A151HZT2   A0A158NDL1   A0A151X900   A0A151IAK1   A0A195F3B2   A0A151J3L5   F4W9A0   A0A088ACR0   A0A182GG75   A0A2J7RFW1   V9IA28   A0A1B6E0V6   A0A310SFR1   A0A0J7KX36   A0A026WB44   A0A3L8DQE3   A0A182PHV9   E2AM73   A0A0A1WRY1   U4UH28   A0A0L7RHF3   A0A1I8NZT1   A0A2M4CGF8   B0WL45   B4K6W7   W5JVN3   A0A182V9E6   A0A182U261   A0A182XIG7   A0A182KZH1   Q7PQ73   A0A182HYR2   A0A1A9XG37   A0A182Y8Q7   A0A1B0G9C3   A0A1I8M2L9   A0A1A9UJR7   A0A182N9X8   A0A3B0K4Q8   A0A182W3I1   A0A182K7D9   A0A3B0K6I3   A0A182RE22   A0A084VB85   A0A1A9Z9K9   A0A182SVU9   A0A1B0BEG6   A0A182QSK2   K7J6I2   A0A1A9WY23   A0A1W4VLH9   A0A0L0CGN2   A0A0R1E4I6   A0A0B4KGG6   Q9VN12   A0A0R1E2Y4   B4MC24   A0A182LZG0   B3LY08   B4NIE0   A0A0A1WDU9   A0A182JMG5   B4JGF5   B4QV08   B4GM46   B4I3M8   A0A336KNY8   B3P1Z6   N6TY53   A0A182FAM0   B5DVN3   B4PTR4   A0A0N0BDA0   A0A0M4ENA3   A0A0K8TXV9   A0A1B6MSW7   W8B819   A0A2H8TDR9   J9K451   A0A2S2P8X2   A0A0A9WM99   E0VUZ2   A0A2H8TZW0   T1I485  

Pubmed

19121390    26354079    28004739    20798317    18362917    19820115    + More
21282665    17510324    21347285    21719571    26483478    24508170    30249741    25830018    23537049    17994087    20920257    23761445    20966253    12364791    14747013    17210077    25244985    25315136    24438588    20075255    26108605    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    17018572    18057021    15632085    24495485    25401762    20566863   

EMBL

BABH01020876    BABH01020877    NWSH01004323    PCG65225.1    KQ459144    KPJ03605.1    + More
KQ461111    KPJ08939.1    GEZM01036836    JAV82378.1    GBYB01012865    JAG82632.1    GBYB01012864    JAG82631.1    GECU01025506    JAS82200.1    GL445549    EFN89468.1    KQ971372    EFA09437.2    GL768421    EFZ11371.1    KYB25176.1    GECZ01000206    JAS69563.1    CH478335    EAT33209.1    KQ434960    KZC12689.1    KQ976664    KYM78300.1    ADTU01001044    ADTU01001045    KQ982402    KYQ56843.1    KQ978223    KYM96270.1    KQ981855    KYN34871.1    KQ980275    KYN17024.1    GL888002    EGI69282.1    JXUM01011370    KQ560329    KXJ83011.1    NEVH01004410    PNF39724.1    JR036456    JR036457    JR036458    AEY57157.1    AEY57158.1    AEY57159.1    GEDC01005781    JAS31517.1    KQ760478    OAD60235.1    LBMM01002249    KMQ95077.1    KK107293    EZA53280.1    QOIP01000005    RLU22496.1    GL440715    EFN65479.1    GBXI01012906    JAD01386.1    KB632294    ERL91668.1    KQ414590    KOC70397.1    GGFL01000063    MBW64241.1    DS231979    EDS30208.1    CH933806    EDW15254.2    ADMH02000289    ETN67110.1    AAAB01008898    EAA09212.5    APCN01005401    CCAG010016995    OUUW01000014    SPP88283.1    SPP88282.1    ATLV01006066    KE524335    KFB35229.1    JXJN01012895    JXJN01012896    AXCN02001605    JRES01000409    KNC31578.1    CM000160    KRK02593.1    KRK02594.1    AE014297    AGB95635.1    AY094726    AAM11079.1    AAN13306.4    KRK02595.1    CH940656    EDW58645.2    KRF78377.1    KRF78378.1    AXCM01000353    CH902617    EDV42864.2    CH964272    EDW83722.2    GBXI01017461    JAC96830.1    CH916369    EDV92624.1    CM000364    EDX11589.1    CH479185    EDW37920.1    CH480821    EDW54821.1    UFQS01000650    UFQT01000650    SSX05758.1    SSX26117.1    CH954181    EDV47769.1    APGK01050286    KB741169    ENN73311.1    CM000070    EDY68441.2    EDW95647.2    KQ435876    KOX70134.1    CP012526    ALC46126.1    GDHF01033037    JAI19277.1    GEBQ01000979    JAT38998.1    GAMC01011793    JAB94762.1    GFXV01000434    MBW12239.1    ABLF02019435    ABLF02019436    GGMR01012737    GGMR01016801    MBY25356.1    MBY29420.1    GBHO01034037    GBRD01011022    JAG09567.1    JAG54802.1    DS235797    EEB17198.1    GFXV01008028    MBW19833.1    ACPB03018838   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000008237    UP000007266    + More
UP000008820    UP000076502    UP000078540    UP000005205    UP000075809    UP000078542    UP000078541    UP000078492    UP000007755    UP000005203    UP000069940    UP000249989    UP000235965    UP000036403    UP000053097    UP000279307    UP000075885    UP000000311    UP000030742    UP000053825    UP000095300    UP000002320    UP000009192    UP000000673    UP000075903    UP000075902    UP000076407    UP000075882    UP000007062    UP000075840    UP000092443    UP000076408    UP000092444    UP000095301    UP000078200    UP000075884    UP000268350    UP000075920    UP000075881    UP000075900    UP000030765    UP000092445    UP000075901    UP000092460    UP000075886    UP000002358    UP000091820    UP000192221    UP000037069    UP000002282    UP000000803    UP000008792    UP000075883    UP000007801    UP000007798    UP000075880    UP000001070    UP000000304    UP000008744    UP000001292    UP000008711    UP000019118    UP000069272    UP000001819    UP000053105    UP000092553    UP000007819    UP000009046    UP000015103   

PRIDE

H9IYA6    Q9VN12   

Pfam

PF01699   Na_Ca_ex        + More
PF03820   Mtc

Interpro

IPR004837   NaCa_Exmemb        + More
IPR004481   K/Na/Ca-exchanger       
IPR004686   Mtc       

ProteinModelPortal

H9IYA6   A0A2A4IZH9   A0A194QF84   A0A0N0PB80   A0A1Y1MBJ7   A0A0C9RVE0   + More
A0A0C9R918   A0A1B6I5M1   E2B4C0   D6X2J2   E9J749   A0A139WB83   A0A1B6H4H0   A0A1S4G2H8   Q16G46   A0A154PLE5   A0A151HZT2   A0A158NDL1   A0A151X900   A0A151IAK1   A0A195F3B2   A0A151J3L5   F4W9A0   A0A088ACR0   A0A182GG75   A0A2J7RFW1   V9IA28   A0A1B6E0V6   A0A310SFR1   A0A0J7KX36   A0A026WB44   A0A3L8DQE3   A0A182PHV9   E2AM73   A0A0A1WRY1   U4UH28   A0A0L7RHF3   A0A1I8NZT1   A0A2M4CGF8   B0WL45   B4K6W7   W5JVN3   A0A182V9E6   A0A182U261   A0A182XIG7   A0A182KZH1   Q7PQ73   A0A182HYR2   A0A1A9XG37   A0A182Y8Q7   A0A1B0G9C3   A0A1I8M2L9   A0A1A9UJR7   A0A182N9X8   A0A3B0K4Q8   A0A182W3I1   A0A182K7D9   A0A3B0K6I3   A0A182RE22   A0A084VB85   A0A1A9Z9K9   A0A182SVU9   A0A1B0BEG6   A0A182QSK2   K7J6I2   A0A1A9WY23   A0A1W4VLH9   A0A0L0CGN2   A0A0R1E4I6   A0A0B4KGG6   Q9VN12   A0A0R1E2Y4   B4MC24   A0A182LZG0   B3LY08   B4NIE0   A0A0A1WDU9   A0A182JMG5   B4JGF5   B4QV08   B4GM46   B4I3M8   A0A336KNY8   B3P1Z6   N6TY53   A0A182FAM0   B5DVN3   B4PTR4   A0A0N0BDA0   A0A0M4ENA3   A0A0K8TXV9   A0A1B6MSW7   W8B819   A0A2H8TDR9   J9K451   A0A2S2P8X2   A0A0A9WM99   E0VUZ2   A0A2H8TZW0   T1I485  

PDB

3V5U     E-value=1.17851e-05,     Score=115

KEGG

101735406    no KO assigned | (RefSeq) probable sodium/potassium/calcium exchanger CG1090

GO

GO:0055085   GO:0016021   GO:0008273   GO:0070588   GO:0006874   GO:0005262   GO:0005887   GO:0006814   GO:0006816   GO:0015293   GO:0015075   GO:0005524   GO:0006468   GO:0008270   GO:0005215   GO:0006270   GO:0042555   GO:0003707   GO:0006281   GO:0006259  

PANTHER

PTHR10846  

Subcellular location

Membrane  

Length:

268

Number of predicted TMHs:

5

Exp number of AAs in TMHs:

111.41379

Exp number, first 60 AAs:

0.00081

Total prob of N-in:

0.99078

inside

1  -  107

TMhelix

108  -  130

outside

131  -  133

TMhelix

134  -  156

inside

157  -  167

TMhelix

168  -  190

outside

191  -  204

TMhelix

205  -  227

inside

228  -  233

TMhelix

234  -  256

outside

257  -  268

 

 

Pi

226.501954

Theta

181.147047

Tajima's D

0.860957

CLR

0

CSRT

0.622168891555422

Interpretation

Uncertain