Gene

KWMTBOMO15748  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002330

Annotation

proline_synthetase_co-transcribed_bacterial-like_protein_[Bombyx_mori]

Location

Bomo_Chr26(+):8828429-8831818      View in EpiBrowser

Full name

Pyridoxal phosphate homeostasis protein      

Alternative Name

Proline synthase co-transcribed bacterial homolog protein

Location in the cell

Cytoplasmic   Reliability : 1.681 Mitochondrial   Reliability : 1.723

CDS

ATGAGGATAATTAAATCTTCAGTTATGACCAGTGAAGTCGATGCTAAAGTTGACATAATGTATGGATTGAAGACGGTTCTTTCACAAATTGAAATTGCCGTGGCCAGAAGAAGTAAAGACCTACCTCAGATAGCACCAAGATTGGTTGCTGTATCAAAAATTAAACCTGTCGAACTTATTGTGGAAGCTTACAATGCTGGCCAGAGGCACTTCGGAGAAAACTATGTAAACGAATTAAGTGATAAAGCCAGTGATCCATTAATACTGGAAAAATGCAAAGACATTAAATGGCACTTCATTGGACATTTACAAACAAACAAGATTAACAAACTACTTGGTTCGCCAGGCTTGTTTATGGTTGAAACAGTTGATTCAGAAAAATTAGCTGATAATTTGAATAAGCAATGGTTGAAATATAGGAAGGAGAAGGAAAGATTGAGAGTTATGGTACAAGTTAATACTAGTGGTGAACAAGCAAAAAGCGGCTTAGAACCATTGGAAACAACAAAAGCTGTTGAGCACATTCTCGAAAACTGTCCAAACCTAGATTTCCAGGGACTGATGACCATAGGGCAGTATGACTATGATATTACCAAAGGACCAAATCCTGACTATCTGTGCCTAATAAAATGCAGGCAAGAAGTGTGTGAGAAGTTGAATTTGGATATCAAAGATGTTGAGTTATCAATGGGAATGTCTTCAGATTTTGCACATGCTATTGAATTAGGCGCAACTACAGTTCGGGTTGGTTCTACTATTTTTGGAGCAAGGCCGCCGAAAAATTCATAA

Protein

MRIIKSSVMTSEVDAKVDIMYGLKTVLSQIEIAVARRSKDLPQIAPRLVAVSKIKPVELIVEAYNAGQRHFGENYVNELSDKASDPLILEKCKDIKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVEHILENCPNLDFQGLMTIGQYDYDITKGPNPDYLCLIKCRQEVCEKLNLDIKDVELSMGMSSDFAHAIELGATTVRVGSTIFGARPPKNS

Description

Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

Cofactor

pyridoxal 5'-phosphate

Similarity

Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

Feature

chain  Pyridoxal phosphate homeostasis protein

Uniprot

Q2F662   H9IYJ6   A0A0N1IF25   A0A194QIG2   A0A2W1BFV7   A0A2H1WHM4   + More
A0A212EL27   S4PA59   A0A1B6LK24   N6U5X1   A0A3Q2QN12   A0A3B3XMK1   U4U5Z1   A0A146NLZ2   M3ZQ71   A0A3P8TF67   A0A3Q1ETS8   A0A096M0T1   A0A3Q1AQU9   A0A3B4Y9B0   A0A3B4ULT2   A0A087YE34   A0A3B3TVZ9   A0A3P9NEC9   A0A3Q0RHT6   A0A3B5KNR0   A0A3Q2Y2Z8   A0A1A8GCQ5   A0A1B6KJU9   A0A1Y1K2I7   A0A3B4ULV7   A0A3B4D0E5   A0A3B5B705   A0A3Q3A941   I3IVL2   A0A3B4AFA8   A0A1A8I7S6   A0A1A8QEY3   A0A3B4FQB2   A0A3Q2V3P0   A0A3Q4MIC5   A0A3P8NWT4   A0A3P9D6M4   A0A1A8SHR4   A0A1A8D5X9   A0A0N8JZF4   A0A3Q2E3Z2   A0A1A8RGZ5   A0A3Q1JRS6   A0A1A7WSE9   A0A3B3T2C1   A0A0S7JX53   A0A3B3BVM8   A0A3Q3IF63   H3CCX0   A0A3S2PUW4   A0A3Q3MFD8   I3IVL3   A0A3B1ID89   A0A3Q7Q8B4   H2S9R8   A0A158N9P3   A0A088AER7   H9G3C9   W5U6X0   A0A1B6JE58   H0Z2K7   D6WZU8   A0A1B6HFI3   A0A2I4BVL3   A0A315WD19   A0A2A3ECU6   A0A1W7REK3   B5X4B5   H2L9W8   A0A3P9LFM9   T1DLS6   A0A218UK76   C1BF86   H2L9W9   A0A3P9MMP2   J3S9B4   A0A1U7QI70   A0A3Q3FPY7   A0A1V4KHI1   A0A2U9C1U3   A0A2D4FFA1   E1C516   A0A2P4T2D1   A0A2U3VI01   A0A195F7Q6   F6TK15   A0A337S203   L5LS66   C1BH33   A0A091HRT6   G1P9A7   F4WTT5   B1H1M3   I3M684  

Pubmed

19121390    26354079    28756777    22118469    23622113    23537049    + More
23542700    28004739    25186727    25463417    29240929    29451363    15496914    25329095    21551351    21347285    21881562    23127152    20360741    18362917    19820115    29703783    26358130    20433749    17554307    23758969    23025625    15592404    20431018    17975172    21993624    21719571    23594743   

EMBL

DQ311210    ABD36155.1    BABH01020804    KQ460794    KPJ12185.1    KQ458761    + More
KPJ05184.1    KZ150122    PZC73161.1    ODYU01008638    SOQ52392.1    AGBW02014148    OWR42185.1    GAIX01006532    JAA86028.1    GEBQ01015980    JAT23997.1    APGK01038535    KB740960    ENN77010.1    KB631679    ERL85350.1    GCES01153895    JAQ32427.1    AYCK01013129    HAEB01014345    HAEC01000072    SBQ68149.1    GEBQ01028248    JAT11729.1    GEZM01097336    JAV54270.1    AERX01047889    HAED01006905    SBQ93052.1    HAEF01013247    HAEG01012198    SBR91719.1    HAEI01014745    SBS17214.1    HADZ01022295    HAEA01000409    SBP86236.1    JARO02004087    KPP69185.1    HAEH01016913    SBS05301.1    HADW01007240    HADX01008700    SBP08640.1    GBYX01228849    GBYX01228845    GBYX01228844    GBYX01228842    GBYX01228840    JAO68987.1    CM012443    RVE70290.1    ADTU01009726    AAWZ02027240    JT405720    AHH37294.1    GECU01010318    JAS97388.1    ABQF01056100    ABQF01056101    KQ971372    EFA09643.1    GECU01034347    JAS73359.1    NHOQ01000023    PWA33756.1    KZ288301    PBC28841.1    GDAY02001870    JAV49562.1    BT045884    ACI34146.1    GAAZ01001892    JAA96051.1    MUZQ01000263    OWK53830.1    BT073265    ACO07689.1    JU175494    GBEX01002615    AFJ51018.1    JAI11945.1    LSYS01003090    OPJ83909.1    CP026253    AWP09102.1    IACJ01069160    LAA46184.1    AADN05000189    PPHD01011511    POI30519.1    KQ981727    KYN36650.1    AAMC01017469    AAMC01017470    AAMC01017471    AANG04001605    KB108646    ELK28865.1    BT073912    ACO08336.1    KL217810    KFO99003.1    AAPE02012457    AAPE02012458    GL888344    EGI62400.1    CT025912    BC160662    AAI60662.1    AGTP01097604    AGTP01097605    AGTP01097606   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000019118    UP000265000    + More
UP000261480    UP000030742    UP000002852    UP000265080    UP000257200    UP000028760    UP000257160    UP000261360    UP000261420    UP000261500    UP000242638    UP000261340    UP000261380    UP000264820    UP000261440    UP000261400    UP000264800    UP000005207    UP000261520    UP000261460    UP000264840    UP000261580    UP000265100    UP000265160    UP000034805    UP000192224    UP000265020    UP000265040    UP000261540    UP000261560    UP000261600    UP000007303    UP000261640    UP000018467    UP000286641    UP000005226    UP000005205    UP000005203    UP000001646    UP000221080    UP000007754    UP000007266    UP000192220    UP000242457    UP000087266    UP000001038    UP000265180    UP000265200    UP000197619    UP000189706    UP000261660    UP000190648    UP000246464    UP000000539    UP000245340    UP000078541    UP000008143    UP000011712    UP000054308    UP000001074    UP000007755    UP000000437    UP000005215   

PRIDE

Q2F662    H9IYJ6   

Pfam

PF01168   Ala_racemase_N

Interpro

IPR011078   PyrdxlP_homeostasis        + More
IPR029066   PLP-binding_barrel       
IPR001608   Ala_racemase_N       
IPR007230   Peptidase_S59       

SUPFAM

SSF51419   SSF51419       

Gene 3D

3.20.20.10    

ProteinModelPortal

Q2F662   H9IYJ6   A0A0N1IF25   A0A194QIG2   A0A2W1BFV7   A0A2H1WHM4   + More
A0A212EL27   S4PA59   A0A1B6LK24   N6U5X1   A0A3Q2QN12   A0A3B3XMK1   U4U5Z1   A0A146NLZ2   M3ZQ71   A0A3P8TF67   A0A3Q1ETS8   A0A096M0T1   A0A3Q1AQU9   A0A3B4Y9B0   A0A3B4ULT2   A0A087YE34   A0A3B3TVZ9   A0A3P9NEC9   A0A3Q0RHT6   A0A3B5KNR0   A0A3Q2Y2Z8   A0A1A8GCQ5   A0A1B6KJU9   A0A1Y1K2I7   A0A3B4ULV7   A0A3B4D0E5   A0A3B5B705   A0A3Q3A941   I3IVL2   A0A3B4AFA8   A0A1A8I7S6   A0A1A8QEY3   A0A3B4FQB2   A0A3Q2V3P0   A0A3Q4MIC5   A0A3P8NWT4   A0A3P9D6M4   A0A1A8SHR4   A0A1A8D5X9   A0A0N8JZF4   A0A3Q2E3Z2   A0A1A8RGZ5   A0A3Q1JRS6   A0A1A7WSE9   A0A3B3T2C1   A0A0S7JX53   A0A3B3BVM8   A0A3Q3IF63   H3CCX0   A0A3S2PUW4   A0A3Q3MFD8   I3IVL3   A0A3B1ID89   A0A3Q7Q8B4   H2S9R8   A0A158N9P3   A0A088AER7   H9G3C9   W5U6X0   A0A1B6JE58   H0Z2K7   D6WZU8   A0A1B6HFI3   A0A2I4BVL3   A0A315WD19   A0A2A3ECU6   A0A1W7REK3   B5X4B5   H2L9W8   A0A3P9LFM9   T1DLS6   A0A218UK76   C1BF86   H2L9W9   A0A3P9MMP2   J3S9B4   A0A1U7QI70   A0A3Q3FPY7   A0A1V4KHI1   A0A2U9C1U3   A0A2D4FFA1   E1C516   A0A2P4T2D1   A0A2U3VI01   A0A195F7Q6   F6TK15   A0A337S203   L5LS66   C1BH33   A0A091HRT6   G1P9A7   F4WTT5   B1H1M3   I3M684  

PDB

1CT5     E-value=6.54075e-36,     Score=375

KEGG

693086    K06997 PLP dependent protein | (RefSeq) proline synthetase co-transcribed bacterial-like protein

GO

GO:0030170   GO:0005643   GO:0017056  

PANTHER

PTHR10146  

Length:

262

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01975

Exp number, first 60 AAs:

0.0024

Total prob of N-in:

0.10394

outside

1  -  262

 

 

Pi

236.664261

Theta

150.431033

Tajima's D

1.768103

CLR

17.77153

CSRT

0.842157892105395

Interpretation

Uncertain