Gene

KWMTBOMO15737

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr26(-):8212158-8216696      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.58 Nuclear   Reliability : 1.669 PlasmaMembrane   Reliability : 1.013

CDS

ATGGACGCTGTATTCGCGGAATTCCTCCGACTTCGCCACCCACAGCTCGCCTCGGAGTTTTTGGCCTTCAAGGCCAATCACACTGCGAGCCCTCTCGAGGACTCCGCCGCGCTCGCTGCTCCTGCGTCGCCTGTACCTGCGTGCAGAGCTTCTGCATTGAGCACCGCAGCCTCTGTCGTGCCTGCCGCTCCCGTGTCGCCTATACTGGCGAGAAAAGCTGCTGCGTCGTCCGCCGTGACCATCGTTTCAGCTGAGCGATCATCCGCGGCCTCCGTCGCGCCCTCTAAAACACCTACACTTGCTCGTAGGTCGCCTGCACCCGCCTCCTCGTGCTCCGACTCTGACTCGGACATGGAGGTCGACCTCGCCCCCGCCTCATCGACGGATGGATTCACCCTGGTACAGAAGGGTAAGAAGCGTGCCGCGGAGTCTCGAGCTCCCGCGGCCGCTAAAATTAGCAAAGCCGTGAACGCGTCGCGCCCCCGCCCTCAGACTCCCGTTGCGCCCCCAGCCCGTGCCACTCCGTCGCCGCGTCCGGTGGCACAAAATAAAACCCAGACCCCTCCCCCGGTTATCCTTCAGGAGAAGGCAGCTTGGGATCGAGTTTGCCTGGCCCTTAAGGCCAAAAATATAAATTTCACGAATGCCCGTAACCTCGCGAACGGCATTCAAATTAAGGTTCAAACACCCGACGACCATAGGGCCCTCTCTTCTTACCTCCGTAAGGAGCGTATAAGTTTCCATACGTATACGCTCCAGGAGGAGCGCGAACTCCGCGTTGTAATACGCGGAATCCCTAAAGAGTTAGATGTAGAGCTCGTAAAAGCCGACCTGTTAGAACAAGGCCTACCAGTGAATTCTGTGCACCGTATGCACACCGGTCGCGGTAGGGAGCCATATAATATGGTTCTAGTCGCTCTCCAGCCTACCCCCGAGGTGCAGGAGACCCTACTTAAGCCCGCGCGCCGTGACCCTAAAATCGCGAACTATAACATGGTCAGGAACGACAGGCTCTCTGCCCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGTATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGCTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGGTATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCTGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACAAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTCTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAA

Protein

MDAVFAEFLRLRHPQLASEFLAFKANHTASPLEDSAALAAPASPVPACRASALSTAASVVPAAPVSPILARKAAASSAVTIVSAERSSAASVAPSKTPTLARRSPAPASSCSDSDSDMEVDLAPASSTDGFTLVQKGKKRAAESRAPAAAKISKAVNASRPRPQTPVAPPARATPSPRPVAQNKTQTPPPVILQEKAAWDRVCLALKAKNINFTNARNLANGIQIKVQTPDDHRALSSYLRKERISFHTYTLQEERELRVVIRGIPKELDVELVKADLLEQGLPVNSVHRMHTGRGREPYNMVLVALQPTPEVQETLLKPARRDPKIANYNMVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNPDSIPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRYPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKQKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSRILIMQEPVTVDALDTSLRIHQIQ

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   V5GNJ2   A0A139WA11   V5GNF3   X1WLB2   A0A023EYS8   X1WNI2   A0A2S2PPK8   A0A2S2QEE0   A0A023EZE6   K7IN67   A0A2J7PU96   A0A224XB44   A0A2J7QR37   A0A2J7PBY3   A0A2J7QY69   A0A2S2Q383   X1WZH0   A0A087UCW3   A0A224X6Q4   A0A2J7Q6J2   J9LFC9   A0A224XI99   A0A224X6T4   A0A224X6S1   A0A2M4BD67   A0A2M4BDV6   A0A224X6U5   A0A2J7QB68   A0A1Y1KFR3   A0A3N5Z7I3   A0A2J7PVX3   Q07995   A0A2J7PDM0   A0A2M4CV52   A0A2S2NH02   A0A087UGF5   A0A224XJI0   A0A069DZL8   A0A2M4CV42   A0A0A9YJ00   A0A2S2R9D4   A0A224X746   Q95SX7   A0A023F069   Q9NBX4   A0A2A4IUM2   A0A224XIB0   A0A2H8TKI9   A0A2M4BD83   A0A142LX26   A0A224X6W2   A0A0V0G5B6   A0A142LX49   A0A2M4BD66   A0A2S2NPG3   A0A2M4BDA5   A0A2M4BD62   A0A2S2P698   A0A224X6R6   A0A2J7Q0S7   A0A2S2P3X8   A0A069DX78   A0A232ENU1  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    20075255    30086797    8387152    26334808    25401762    7753626    12537569    11405632    25527032    28648823   

EMBL

U07847    AAA17752.1    AB055391    BAB21761.1    AB018558    BAA76304.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    GALX01005299    JAB63167.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    ABLF02042518    ABLF02057746    GBBI01004395    JAC14317.1    ABLF02008153    ABLF02008462    ABLF02008464    GGMR01018716    MBY31335.1    GGMS01006359    MBY75562.1    GBBI01004571    JAC14141.1    NEVH01021205    PNF19912.1    GFTR01008262    JAW08164.1    NEVH01011985    PNF31054.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    GGMS01002992    MBY72195.1    ABLF02034467    KK119261    KFM75202.1    GFTR01008279    JAW08147.1    NEVH01017470    PNF24199.1    ABLF02023911    GFTR01008256    JAW08170.1    GFTR01008261    JAW08165.1    GFTR01008271    JAW08155.1    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    GFTR01008251    JAW08175.1    NEVH01016302    PNF25823.1    GEZM01084969    JAV60363.1    RPOV01000134    RPJ78669.1    NEVH01020940    PNF20481.1    S59870    AAB26437.2    NEVH01026386    PNF14434.1    GGFL01004957    MBW69135.1    GGMR01003864    MBY16483.1    KK119692    KFM76444.1    GFTR01008257    JAW08169.1    GBGD01000415    JAC88474.1    GGFL01005012    MBW69190.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GGMS01017365    MBY86568.1    GFTR01008151    JAW08275.1    AY060438    AAL25477.1    GBBI01003810    JAC14902.1    AF237761    AAF81411.1    NWSH01007753    PCG62823.1    GFTR01008246    JAW08180.1    GFXV01002840    MBW14645.1    GGFJ01001822    MBW50963.1    KU543673    AMS38352.1    GFTR01008260    JAW08166.1    GECL01003538    JAP02586.1    KU543685    AMS38375.1    GGFJ01001844    MBW50985.1    GGMR01006408    MBY19027.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GGMR01012305    MBY24924.1    GFTR01008269    JAW08157.1    NEVH01019963    PNF22185.1    GGMR01011511    MBY24130.1    GBGD01000389    JAC88500.1    NNAY01003095    OXU19992.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000002358    UP000235965    UP000054359    + More
UP000218220    UP000215335   

PRIDE

Q93137    Q9BPQ0    Q9XXW0    Q95SX7    Q9NBX4   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   V5GNJ2   A0A139WA11   V5GNF3   X1WLB2   A0A023EYS8   X1WNI2   A0A2S2PPK8   A0A2S2QEE0   A0A023EZE6   K7IN67   A0A2J7PU96   A0A224XB44   A0A2J7QR37   A0A2J7PBY3   A0A2J7QY69   A0A2S2Q383   X1WZH0   A0A087UCW3   A0A224X6Q4   A0A2J7Q6J2   J9LFC9   A0A224XI99   A0A224X6T4   A0A224X6S1   A0A2M4BD67   A0A2M4BDV6   A0A224X6U5   A0A2J7QB68   A0A1Y1KFR3   A0A3N5Z7I3   A0A2J7PVX3   Q07995   A0A2J7PDM0   A0A2M4CV52   A0A2S2NH02   A0A087UGF5   A0A224XJI0   A0A069DZL8   A0A2M4CV42   A0A0A9YJ00   A0A2S2R9D4   A0A224X746   Q95SX7   A0A023F069   Q9NBX4   A0A2A4IUM2   A0A224XIB0   A0A2H8TKI9   A0A2M4BD83   A0A142LX26   A0A224X6W2   A0A0V0G5B6   A0A142LX49   A0A2M4BD66   A0A2S2NPG3   A0A2M4BDA5   A0A2M4BD62   A0A2S2P698   A0A224X6R6   A0A2J7Q0S7   A0A2S2P3X8   A0A069DX78   A0A232ENU1  

KEGG

105841788    no KO assigned | (RefSeq) predicted GPI-anchored protein 58

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1196

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.01360000000001

Exp number, first 60 AAs:

0.00071

Total prob of N-in:

0.00011

outside

1  -  1196

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

101.73777

CSRT

0

Interpretation

Uncertain