SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO15718
Pre Gene Modal
BGIBMGA002311
Annotation
PREDICTED:_uncharacterized_protein_LOC101739289_[Bombyx_mori]
Full name
DNA-directed RNA polymerase subunit beta      
Location in the cell
Cytoplasmic   Reliability : 1.646 Nuclear   Reliability : 1.628
 

Sequence

CDS
ATGTGTCTAAGTCATGTCATGCCAAAGTTATTTTGGATAGTTTTTATAAGTTATTTAGTTGAACCATGCAGTTCTTTTGTTCTTCGCGCCTACCTCTCCCAACACGGCCTTCATGGAGAGATAGAATTTTCCCACAAAAACGACACCTTAATCAGTATCCGCACAAACCTAAAACCAACATTACAATATCCTGACGGAGTTTGGAGATGGACTATTCACGAGTTTCCTGTCGATTATCGGGATATTTCTGAATCCCGGTGCTCAGAAGAAACTTTAGGGAGAGAAATCATAGATTTGACTGAAGAATTGGGGTATTTAATTATACCTGGGAAAGACCACGCCGAGTTCGAAAGCAAAAATACTTTGACCGGCCCTAATGGACTCTGGGGGAGAAGCATTGTTTTAGAAACAGCAGAGAGAGATCGAATAATCTGTGCATCAATTCTCTCAACTGAGAAGCTGTATGAAACTCATGCTCTAGCCAAATTCACTGCACCGGTGGCAGGTACATTACACTTTAGATGGATCTCCGCTAAAGAGATTGACGAATCCGATTCGTATATCCAAGCTGACTTGTATCATGCTAAAGCAGTTACAGATAAGTCAGAGTACACTGAGCATAAATGGAAGCTCTTTGTGACAGACATATTTGATTCTGATAAGGGAAATTACGAGGACAATTGTAATGTACTGCAAGCAGTCTTCGACCCGGAGAACAATGGAGAAGGCATGAGTGTAGGTGACTTAGATAGTAGATTGGGTCTTATTAAAGTGGCTACGGATGCTAAAGTAAAAAAAGTGAGGACTCTTTATAAAAATGATGTGATAGACATTTTGAAAAATGATATGGAGATGACACGACGAAGTTTGTATGTGGTGATTTTTGATAATAGACATGTCGATAGTTTCTTGGCTTGTGCTAAGTTGAGGCTGATTCCTCCAAAAAGCAGCAAGGTTTTGATCAACATGGACGGAATCCGCGGCACCGTTGATTTTACCCAGCGCTCCCCATTTGACCCGACCTGGGTTAACTTTCAACTTGGTGCTTCCGACATGGAGTATGAATCCAATCTTCGTTTTGTTGGCTCCATGCTTCAATACAACATCAGAGAGTTGCCTCCGAAACTATTGGATGCGAATCAAGTTAATTACATGTGCAATACGACGGGAGATATTTATAATCCCATGGAATTGGACTTGAAGACTTTACCTCCGCCAGGATTAAGTACGCAAGACCACTATCCCGTGGGAGATCTGCTGGGAAAATACAAAGATCGGACCGAATACTTGAACCACAAATATCTTCTGCCTGGTTTGGCTAATGAATTAAGTGGAGCGTATTGGGACGTGTACCTACCATTACAAGGAATTTATTCTGTGGTACACAGATCCCTCGTGTTGGAGAGGAGACCCGGAAAGCGTAATGTGTGTGGAACTATTCTACTTTACGAGGATGGTACAGAATACCAGATACAAATGAGTGGAGCTCAGGTCATCTTCCGGTATCCTATTGTGGGAAGAGTTATTTTCAGGCAGCCGTTGGACCAACCCTGGGAGGACACCACCATAATAATCGAGAGCATGGTACACGCGGATGGAGCCAATGTAAACAACACAAGAGAGCATCGTTGGGCCATCCACGAACACCCCCCGGGGGTTGATTATTACAACTGGACGGGACGATGCCTCAGCGCCGGAAAAGTATACGAGCCCCATAGTCTGGATATAGACACACGACACCCCGAACAGTACTGCAGGAGAGGATTGGAAGGGCTTTGTCGCATTGGAGACTTTACCACGAGGCACGGCATGCTCTCTATAGCTGGAAAGAAAGTGGATAGTGATCGACTAACAAGGAGGCTGTTTACTGACACAGTCATATCGCTGACAGGCAAGCATAGCATCATGAGGAAATCACTACTTATTTATGATGATCACGGACCCGTTGCTAGGGGTGAGAGAATGGCTTGTTCAATAGTGAATGGCCTTCATCGCCGTAAAGCGGTGGTCCGCGATTGGTTCGGAAACGGACAGCAGCTTCAGCTGAAAGGCAAGATTGAAATGACTCAACAATCAGAGTATGACGTCACTAATGTACAAGTCACGATCGAAGGGTTGCAGAATGTAAATGACTATAAAATTCACGTGGTGCCTGTTGAGAAAGAATTGGAATTCCCTTGCGAGAAAGAAACACTGTATGACACATTCAATCCGTTTCATGTGGATAAGTCGCTTAGTCCACCGCCCGCGCAAGGTACTGCTGACCAATACGAGCTCGGAGATTTAGGACTCAAATATGGTTTAATCGATGAAGCGAAAAGTTTCAAGTCCTTTTACAATGAAACACAGGTGTCTTTATTTGGTCCTTACAGTATACTAGGACGATCTGTGGTTCTACATAAAAAGAGCCGTGACCGTAGGTGGGCATGTTCGAGTATAGAGCGAGGGTACAGCCCATCAGAAGCTCGTGAAATCCGAGGGATCGCTTCATTCCACCACCCTGGCGGATTCGCTCGAGGCTACATTCGAATGTCCCAACTCATCCACAATGATGGAAGCACCAGCGATACCGTGATAGAAGTAAAGTTGAGGTATCCGGGAGTGAGAGACAGAAACTATACCCGTAATCACAAATGGGAGATATTCGTGAATCCTGTCGGAGTAGATGCTGCAGTTCAAGTGACTAATACTAGATGTGTAGCTGGTGGTTACCGCTGGAATCCGTACTTCACGCAGCTAGCTGATCCATTGAACCATGATCTATACAGTCAAGAGTGCGGGATTGACAATCCACTGCGGTGTGACGTCGGCGATCTGACTGCCAGATTGGGAACGATTAACATCGGTGGTGAGCGTCAAATGCTCATGGACACAAATTTTCCATTGGAAGGTAAAGTGTCTGCAATGGGACGTTCAATCGTGATCTTCGGTCCGGAAAGAACTAGCGAACGATTTGCTTGCGCCAACATCGAACCCGATAATGACATCATCAAATATGTCAATCTGGTTAGAACGCCGAAATTTGTACTTGGTCAATTCTTAGAAGATATTCGGAAAGTAATGGGTGTTCCTGAGTGGATGGTCAGCGTGGACTCGCGTCGTACTCGCGACCTGCACCACTCTACCTGTATTCAGATCCTACTGCACTTCACTGGACCTCACGCCAACAGACTCGAACTTGATTTTACTAGATTACTAGCGTCCGGAAGATTGGATTCGCCGAGTATATTCATACCCGGCTACGTGGATACGAAGAGAAAGAGGGGTACTCAATATAGACATTGCGGAGTCACAGATCCCAATGAGAAGAAAAGAAATTTAGAGGGGCCGTTTTTATTTTTTGGACCTAAATCCTTAGAAAAGTACAAAAGGCCAGCATTGAAGTATTTGGACCAAGATGAGTTGACGAAAATATATGGAGAGCAAGCGGCTATAGTGGTTTTTAATAACCAGGATTCGGTGCCACTTTCCAGTGGATATTTCCCAAGGTTAAGGAAGATGTTGGAGGGTCAGACTGTGTTGGTTTTGCCGCAGGATTTTTTGGATGTTCACCCGGATTACATCAGCAATGAAACCCAGATGCTTACCCTTCAAGGACCATGGTCAGAAAGAGACGCACAGATGACGGAGACATTTGCTCGGCTCCAAGATATCTATGGAGCTGGGCGGGTTTTAGGGATTTTGGGAAATTCCGTTTCACAAAGTCAATCTCCGGACTACGTCGAAGGTGAATGGTCTAGAGTGAGGAGGCAGACTGGTAATGAAACAACAACACCGTCCGGTCAAGAAGAAGAGAAGATGACTAAAGCTGTCCCTAAATACGCATTATATAATGCAACTGGTCCCCCCGGAAAGGGTGCACTTCTCTACTCATCAGGATGGCCTGAGTTACGTTTAGCGAATGGAAAGAGGGTGGTTCTCAGCAATCAAGTTGGCGAATGTACTGTGAAACCGACAAGGCTTTATACTATGCTAGTTGTCAAATTCGCTGATGGAGACAGTAGAGATAAGATAACCCTCGAATTCAGTTTCAAGCAGTCAGCTGGCTGGTGGACGGCCGTCGGAGTCGAGGTCATATTCGGATCCCTCGAAACATCTGGATTGAATTTGAAGGCACCAGCCCCACCTGATGCTCCTTCAGCAGTGCTGGGTCGTTCTTACCATTGTTCTCAGCCTCTTGTGTATACGTCTGATGAGGCAATTTTAAGACTTCCCGATGTTCAGATGCAAATTTTTATGGATAGCACGGAGAGGTTCGCTGATGCTTTTGATTGCATTGGCTTTACAACTGTGCCGATCTGGTCCGGATTAATGGTGTCATTCATAATGCTGCTAGGGCTGGCGGTGTCTGTTTGCATGATAATGGATATTAAGACCATGGACCGCTTTGAGAGTAACAGAAGCAAACAACTGACGATCACTGTTAATGAATAA
Protein
MCLSHVMPKLFWIVFISYLVEPCSSFVLRAYLSQHGLHGEIEFSHKNDTLISIRTNLKPTLQYPDGVWRWTIHEFPVDYRDISESRCSEETLGREIIDLTEELGYLIIPGKDHAEFESKNTLTGPNGLWGRSIVLETAERDRIICASILSTEKLYETHALAKFTAPVAGTLHFRWISAKEIDESDSYIQADLYHAKAVTDKSEYTEHKWKLFVTDIFDSDKGNYEDNCNVLQAVFDPENNGEGMSVGDLDSRLGLIKVATDAKVKKVRTLYKNDVIDILKNDMEMTRRSLYVVIFDNRHVDSFLACAKLRLIPPKSSKVLINMDGIRGTVDFTQRSPFDPTWVNFQLGASDMEYESNLRFVGSMLQYNIRELPPKLLDANQVNYMCNTTGDIYNPMELDLKTLPPPGLSTQDHYPVGDLLGKYKDRTEYLNHKYLLPGLANELSGAYWDVYLPLQGIYSVVHRSLVLERRPGKRNVCGTILLYEDGTEYQIQMSGAQVIFRYPIVGRVIFRQPLDQPWEDTTIIIESMVHADGANVNNTREHRWAIHEHPPGVDYYNWTGRCLSAGKVYEPHSLDIDTRHPEQYCRRGLEGLCRIGDFTTRHGMLSIAGKKVDSDRLTRRLFTDTVISLTGKHSIMRKSLLIYDDHGPVARGERMACSIVNGLHRRKAVVRDWFGNGQQLQLKGKIEMTQQSEYDVTNVQVTIEGLQNVNDYKIHVVPVEKELEFPCEKETLYDTFNPFHVDKSLSPPPAQGTADQYELGDLGLKYGLIDEAKSFKSFYNETQVSLFGPYSILGRSVVLHKKSRDRRWACSSIERGYSPSEAREIRGIASFHHPGGFARGYIRMSQLIHNDGSTSDTVIEVKLRYPGVRDRNYTRNHKWEIFVNPVGVDAAVQVTNTRCVAGGYRWNPYFTQLADPLNHDLYSQECGIDNPLRCDVGDLTARLGTINIGGERQMLMDTNFPLEGKVSAMGRSIVIFGPERTSERFACANIEPDNDIIKYVNLVRTPKFVLGQFLEDIRKVMGVPEWMVSVDSRRTRDLHHSTCIQILLHFTGPHANRLELDFTRLLASGRLDSPSIFIPGYVDTKRKRGTQYRHCGVTDPNEKKRNLEGPFLFFGPKSLEKYKRPALKYLDQDELTKIYGEQAAIVVFNNQDSVPLSSGYFPRLRKMLEGQTVLVLPQDFLDVHPDYISNETQMLTLQGPWSERDAQMTETFARLQDIYGAGRVLGILGNSVSQSQSPDYVEGEWSRVRRQTGNETTTPSGQEEEKMTKAVPKYALYNATGPPGKGALLYSSGWPELRLANGKRVVLSNQVGECTVKPTRLYTMLVVKFADGDSRDKITLEFSFKQSAGWWTAVGVEVIFGSLETSGLNLKAPAPPDAPSAVLGRSYHCSQPLVYTSDEAILRLPDVQMQIFMDSTERFADAFDCIGFTTVPIWSGLMVSFIMLLGLAVSVCMIMDIKTMDRFESNRSKQLTITVNE

Summary

Description
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic Activity
a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
Similarity
Belongs to the RNA polymerase beta chain family.
EC Number
2.7.7.6
EMBL
BABH01020641    KZ150119    PZC73227.1    KQ460820    KPJ12105.1    CCAG010012086    + More
JRES01001112    KNC25460.1    GAKP01022154    JAC36798.1    GDHF01032552    JAI19762.1    GAMC01010656    JAB95899.1    GAMC01010655    JAB95900.1    GBXI01009574    JAD04718.1    CH940652    EDW59275.1    KB632302    ERL91774.1    AJVK01013270    CH933806    EDW14354.1    CH964272    EDW84424.2    CH916369    EDV93218.1    BT133436    AFH68360.1    AE014297    AAF57015.5    BT011091    AAR82757.1    GFDF01000542    JAV13542.1    GFDF01000639    JAV13445.1    CM000160    EDW99071.1    CH477245    EAT46219.1    CH954182    EDV53103.1    CP012526    ALC47543.1    JXUM01097745    KQ564367    KXJ72380.1    CH480819    EDW53487.1    CM000070    EDY67509.2    OUUW01000041    SPP89941.1    DS232775    EDS45594.1    CH479186    EDW39378.1    ATLV01017615    KE525177    KFB42334.1    GFDL01004777    JAV30268.1    KK107364    EZA51911.1    GL446209    EFN88242.1    ADMH02000547    ETN65975.1    KQ760287    OAD60882.1    KQ977306    KYN03611.1    KQ434996    KZC13221.1    GGFJ01001004    MBW50145.1    AXCM01004394    CH902617    EDV44106.1    KQ971372    EFA10695.2    GGFM01005976    MBW26727.1    AXCN02000266    GEZM01017316    JAV90775.1    GGFM01002237    MBW22988.1    APCN01000894    AAAB01008987    EAA00894.5    QOIP01000007    RLU20684.1    KQ414657    KOC65778.1    NNAY01001064    OXU25271.1    APGK01029566    KB740735    ENN79202.1    KZ288357    PBC27153.1    KQ976563    KYM80572.1    KQ981738    KYN36526.1    KQ982730    KYQ51514.1    NEVH01020342    PNF21479.1    KK853179    KDR10216.1    GL437183    EFN70893.1    DS235200    EEB13211.1    PYGN01001796    PSN32762.1    GECZ01009444    JAS60325.1    GECL01002022    JAP04102.1    GDHC01006777    JAQ11852.1    GDHC01012219    JAQ06410.1   
Pfam
PF00080   Sod_Cu        + More
PF05827   ATP-synt_S1
PF00005   ABC_tran
PF12848   ABC_tran_Xtn
PF09995   DUF2236
PF04565   RNA_pol_Rpb2_3
PF00562   RNA_pol_Rpb2_6
PF04561   RNA_pol_Rpb2_2
PF04566   RNA_pol_Rpb2_4
PF04560   RNA_pol_Rpb2_7
PF04563   RNA_pol_Rpb2_1
PF04567   RNA_pol_Rpb2_5
Interpro
IPR036423   SOD-like_Cu/Zn_dom_sf        + More
IPR008388   ATPase_V1-cplx_s1su       
IPR001424   SOD_Cu_Zn_dom       
IPR011992   EF-hand-dom_pair       
IPR002048   EF_hand_dom       
IPR018247   EF_Hand_1_Ca_BS       
IPR027417   P-loop_NTPase       
IPR003439   ABC_transporter-like       
IPR017871   ABC_transporter_CS       
IPR032781   ABC_tran_Xtn       
IPR003593   AAA+_ATPase       
IPR018713   DUF2236       
IPR037033   DNA-dir_RNAP_su2_hyb_sf       
IPR007645   RNA_pol_Rpb2_3       
IPR007646   RNA_pol_Rpb2_4       
IPR037034   RNA_pol_Rpb2_2_sf       
IPR007641   RNA_pol_Rpb2_7       
IPR007644   RNA_pol_bsu_protrusion       
IPR014724   RNA_pol_RPB2_OB-fold       
IPR007642   RNA_pol_Rpb2_2       
IPR007120   DNA-dir_RNAP_su2_dom       
IPR015712   DNA-dir_RNA_pol_su2       
IPR007647   RNA_pol_Rpb2_5       
IPR007121   RNA_pol_bsu_CS       
SUPFAM
SSF49329   SSF49329        + More
SSF47473   SSF47473       
SSF52540   SSF52540       
PDB
2E46     E-value=0.0863436,     Score=89

Ontologies

Topology

SignalP
Position:   1 - 25,         Likelihood:  0.780353
 
 
Length:
1477
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
25.18639
Exp number, first 60 AAs:
2.52987
Total prob of N-in:
0.11768
outside
1  -  1429
TMhelix
1430  -  1452
inside
1453  -  1477
 
 

Population Genetic Test Statistics

Pi
226.794193
Theta
160.948418
Tajima's D
1.677932
CLR
0.383967
CSRT
0.826458677066147
Interpretation
Uncertain
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