Gene

KWMTBOMO15717  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002259

Annotation

myosin_regulatory_light_chain_2_[Bombyx_mori]

Location

Bomo_Chr26(-):7224677-7227211      View in EpiBrowser

Full name

Myosin regulatory light chain 2      

Location in the cell

Cytoplasmic   Reliability : 1.298 Nuclear   Reliability : 1.903

CDS

ATGGCGGATAAGGACAAGAAGGTAAAGAAGAAGAAGGCGAAAGAAGACGCGCCCGCCGAAGAGGCCCCAGCAGCGGCCGCTCCCGCCGGTGACAGGCAATCCTCTCGCGGAAGCCGCAAGGCTAAGCGCACCGGATCCAATGTCTTCTCTATGTTCTCACAGAAGCAGGTCGCTGAGTTCAAGGAGGCATTCCAGCTAATGGACCACGACAAGGATGGCATCATCGGCAAGAACGACTTGCGCGCCACCTTCGACTCCCTGGGCAGGCTCGCGTCCGAGAAGGAGCTCGATGAGATGGTCGGTGAGGCTTCTGGCCCCATCAACTTCACTCAGCTCTTGACTCTGTTCGCCAACCGCATGTCCGGCGGCTCTGACGAAGATGACGTCGTTATCAACGCCTTCAAGACCTTCGATGAAGAGGGAAAGATCGATTCTGAAAGGCTCAGGCACGCCCTCATGACCTGGGGCGACAAGTTCTCCGCCGACGAAGTCGACGAGGCTTACGACCAGATGGACATTGACGACAAGGGTTACATCGACACCACCAAGCTGATCGCCATGCTGACCGCCAGCGCTGAGGAGGAGGAAGGCGGTGAAGCCGCGTAA

Protein

MADKDKKVKKKKAKEDAPAEEAPAAAAPAGDRQSSRGSRKAKRTGSNVFSMFSQKQVAEFKEAFQLMDHDKDGIIGKNDLRATFDSLGRLASEKELDEMVGEASGPINFTQLLTLFANRMSGGSDEDDVVINAFKTFDEEGKIDSERLRHALMTWGDKFSADEVDEAYDQMDIDDKGYIDTTKLIAMLTASAEEEEGGEAA

Subunit

Myosin is a hexamer of 2 heavy chains and 4 light chains.

Miscellaneous

This chain binds calcium.
MLC2 has at least two isoforms in each type of muscle and the isoforms of tubular muscle differ slightly from those of fibrillar muscle. These isoforms may arise through post-translational modifications.

Keywords

Calcium   Complete proteome   Direct protein sequencing   Metal-binding   Motor protein   Muscle protein   Myosin   Phosphoprotein   Reference proteome   Repeat   Acetylation  

Feature

chain  Myosin regulatory light chain 2

Uniprot

B5AK67   B0FL77   Q1HPS0   E3UBU0   A0A2W1BK64   A0A2A4J3V3   + More
A0A3S2LRL0   A0A2H1WB05   Q5MGI7   I4DLU1   A0A0N0P9R0   I4DIC1   A0A0N1I6D9   A0A212FEC1   Q49M29   A0A2A4J2X4   G8XWV4   A0A2P0XIZ1   A0ERA8   H6WP59   G9JWG6   A0A067QP73   G8XWV5   A0A2J7PYT5   A0A1B0GPH3   A0A1B0CUS5   A0A1L8E5Y9   A0A1D2N9I7   A0A026W778   E9IQN0   A0A348G637   E2B7V0   A0A151JYH7   A0A151WKZ2   A0A310SQD1   F4X2D8   A0A0J7KHF9   A7L498   A0A195E2X3   A0A0M8ZSQ2   E2A6Q3   A0A087ZND8   V9IJE8   A0A2A3E6N0   A0A3L8DJR6   A0A1Q3FMR1   A0A1Q3FMP6   A0A1Q3FMJ6   B0XDR8   Q45FA2   A0A182VZC5   A0A182MEW9   A0A182NS38   A0A182QHM0   A0A182R616   A0A1B6HV30   A0A182J7V7   A0A182YAJ5   A0A1B6E048   A0A182USU7   A0A182U9U6   A0A182L9R7   A0A182WSI3   Q7PUV3   A0A182HLD5   A0A1B6LZ31   A0A182PGN3   T1E798   A0A182F6F8   A0A023EJK6   W5JUN5   T1DIR1   A0A0A1G410   A0A1B6F9K6   Q17HX1   A0A336K5L6   A0A1I8PEJ1   A0A226E6Y2   B3LZC8   A0A034VWH3   A0A1W4VQ69   P18432   A0A0K8VGI3   B4PLT5   A0A1L8EHR3   T1PHS3   A0A1W4XP04   B4NGS8   E9FW72   A0A3B0KMS9   Q29C22   V5JDH1   A0A1I9WLG0   B4M6K0   B4K821   E5L9W5   A0A0M5JCZ6  

Pubmed

11280994    28756777    16023793    22651552    26354079    22118469    + More
24845553    27289101    24508170    21282665    20798317    21719571    30249741    18691666    25244985    20966253    12364791    14747013    17210077    24945155    26483478    20920257    23761445    24330624    17510324    17994087    25348373    3025224    3018498    10731132    12537572    12537569    18327897    17550304    25315136    21292972    15632085    27538518    20978910   

EMBL

EU854290    ACF59735.1    EU332913    FJ156107    ABY50568.1    ACI05250.1    + More
DQ443332    ABF51421.1    HM182104    ADL09420.1    KZ150119    PZC73226.1    NWSH01003383    PCG66416.1    RSAL01000022    RVE52327.1    ODYU01007463    SOQ50259.1    AY829799    AAV91413.1    AK402259    BAM18881.1    KQ459199    KPJ02965.1    AK401039    BAM17661.1    KQ460820    KPJ12106.1    AGBW02008963    OWR52063.1    AY700062    AAW22542.1    PCG66415.1    FJ855496    AEV23878.1    KY661299    AVA17386.1    DQ389157    ABD47458.1    JQ279816    AEZ35213.1    JN982315    AEV53595.1    KK853179    KDR10217.1    FJ855497    AEV23879.1    NEVH01020342    PNF21503.1    AJVK01059683    AJWK01029614    GFDF01000129    JAV13955.1    LJIJ01000134    ODN01919.1    KK107364    EZA51910.1    GL764841    EFZ17125.1    FX985576    BBF97910.1    GL446209    EFN88243.1    KQ981477    KYN41441.1    KQ982988    KYQ48528.1    KQ760287    OAD60883.1    GL888578    EGI59363.1    LBMM01007515    KMQ89669.1    EF660908    ABS19976.1    KQ979701    KYN19515.1    KQ435897    KOX69196.1    GL437183    EFN70893.1    JR048855    AEY60782.1    KZ288357    PBC27154.1    QOIP01000007    RLU20684.1    GFDL01006269    JAV28776.1    GFDL01006272    JAV28773.1    GFDL01006268    JAV28777.1    DS232775    EDS45595.1    DQ140391    AAZ67334.1    AXCM01004394    AXCN02000266    GECU01029184    GECU01025247    JAS78522.1    JAS82459.1    GEDC01006003    JAS31295.1    AAAB01008987    EAA00945.3    APCN01000894    GEBQ01011082    JAT28895.1    GAMD01003237    JAA98353.1    JXUM01097746    GAPW01004387    KQ564367    JAC09211.1    KXJ72381.1    ADMH02000084    ETN67861.1    GALA01000826    JAA94026.1    KM371003    AIY53682.1    GECZ01022860    JAS46909.1    CH477245    EAT46218.1    UFQS01000090    UFQT01000090    SSW99142.1    SSX19524.1    LNIX01000006    OXA53080.1    CH902617    EDV44107.2    GAKP01012495    JAC46457.1    M28643    M11947    AE014297    AY060369    GDHF01014347    JAI37967.1    CM000160    EDW99072.2    GFDG01000660    JAV18139.1    KA647438    AFP62067.1    CH964272    EDW84425.2    GL732525    EFX88976.1    OUUW01000041    SPP89940.1    CM000070    EAL26824.3    KC122898    AGI96977.1    KU932344    APA33980.1    CH940652    EDW59276.2    CH933806    EDW14355.2    HQ384096    ADQ64589.1    CP012526    ALC47544.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000053240    UP000007151    + More
UP000027135    UP000235965    UP000092462    UP000092461    UP000094527    UP000053097    UP000008237    UP000078541    UP000075809    UP000007755    UP000036403    UP000078492    UP000053105    UP000000311    UP000005203    UP000242457    UP000279307    UP000002320    UP000075920    UP000075883    UP000075884    UP000075886    UP000075900    UP000075880    UP000076408    UP000075903    UP000075902    UP000075882    UP000076407    UP000007062    UP000075840    UP000075885    UP000069272    UP000069940    UP000249989    UP000000673    UP000008820    UP000095300    UP000198287    UP000007801    UP000192221    UP000000803    UP000002282    UP000095301    UP000192223    UP000007798    UP000000305    UP000268350    UP000001819    UP000008792    UP000009192    UP000092553   

PRIDE

Q1HPS0    P18432   

Pfam

PF13405   EF-hand_6        + More
PF13833   EF-hand_8
PF00036   EF-hand_1
PF00080   Sod_Cu

Interpro

IPR011992   EF-hand-dom_pair        + More
IPR002048   EF_hand_dom       
IPR018247   EF_Hand_1_Ca_BS       
IPR001424   SOD_Cu_Zn_dom       
IPR036423   SOD-like_Cu/Zn_dom_sf       

SUPFAM

SSF47473   SSF47473        + More
SSF49329   SSF49329       

Gene 3D

2.60.40.200    

CDD

cd00051  EFh

ProteinModelPortal

B5AK67   B0FL77   Q1HPS0   E3UBU0   A0A2W1BK64   A0A2A4J3V3   + More
A0A3S2LRL0   A0A2H1WB05   Q5MGI7   I4DLU1   A0A0N0P9R0   I4DIC1   A0A0N1I6D9   A0A212FEC1   Q49M29   A0A2A4J2X4   G8XWV4   A0A2P0XIZ1   A0ERA8   H6WP59   G9JWG6   A0A067QP73   G8XWV5   A0A2J7PYT5   A0A1B0GPH3   A0A1B0CUS5   A0A1L8E5Y9   A0A1D2N9I7   A0A026W778   E9IQN0   A0A348G637   E2B7V0   A0A151JYH7   A0A151WKZ2   A0A310SQD1   F4X2D8   A0A0J7KHF9   A7L498   A0A195E2X3   A0A0M8ZSQ2   E2A6Q3   A0A087ZND8   V9IJE8   A0A2A3E6N0   A0A3L8DJR6   A0A1Q3FMR1   A0A1Q3FMP6   A0A1Q3FMJ6   B0XDR8   Q45FA2   A0A182VZC5   A0A182MEW9   A0A182NS38   A0A182QHM0   A0A182R616   A0A1B6HV30   A0A182J7V7   A0A182YAJ5   A0A1B6E048   A0A182USU7   A0A182U9U6   A0A182L9R7   A0A182WSI3   Q7PUV3   A0A182HLD5   A0A1B6LZ31   A0A182PGN3   T1E798   A0A182F6F8   A0A023EJK6   W5JUN5   T1DIR1   A0A0A1G410   A0A1B6F9K6   Q17HX1   A0A336K5L6   A0A1I8PEJ1   A0A226E6Y2   B3LZC8   A0A034VWH3   A0A1W4VQ69   P18432   A0A0K8VGI3   B4PLT5   A0A1L8EHR3   T1PHS3   A0A1W4XP04   B4NGS8   E9FW72   A0A3B0KMS9   Q29C22   V5JDH1   A0A1I9WLG0   B4M6K0   B4K821   E5L9W5   A0A0M5JCZ6  

PDB

3JBH     E-value=1.46311e-42,     Score=431

KEGG

778518    no KO assigned | (RefSeq) MLC-2; myosin regulatory light chain 2

GO

GO:0005509   GO:0016459   GO:0006801   GO:0060361   GO:0003012   GO:0030016   GO:0030239   GO:0007010   GO:0020037   GO:0004983   GO:0005634   GO:0006270   GO:0042555   GO:0003707   GO:0006281   GO:0006259  

Length:

201

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00112

Exp number, first 60 AAs:

0.00015

Total prob of N-in:

0.54141

inside

1  -  201

 

 

Pi

220.971902

Theta

211.682789

Tajima's D

0.498102

CLR

0.576415

CSRT

0.514624268786561

Interpretation

Uncertain