Gene

KWMTBOMO15652  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010687

Annotation

PREDICTED:_isocitrate_dehydrogenase_[NAD]_subunit_beta?_mitochondrial_[Bombyx_mori]

Location

Bomo_Chr26(-):5287297-5296296      View in EpiBrowser

Full name

Isocitrate dehydrogenase [NAD] subunit, mitochondrial      

Location in the cell

Cytoplasmic   Reliability : 1.502 Mitochondrial   Reliability : 1.787

CDS

ATGTCCTTTCTTAGCAGGAATATTTTTCGAGCTGTTATGCAGGGATCTCAACATGTTGGAAAGGGTGTACACACAAGTTCGGTAACAACGGAGAAAAATCAACCGAGGGCAACAAAGGAAGGTCGTATCAAATGCACCTTGATTCCTGGGGACGGTGTAGGTCCTGAGCTTGTCTACGCTGTACAAGAAGTTTTCAAGGCGGCCAGCATTCCAGTGGACTTTGAATCCTTTTTCTTTTCTGAAGTGAATCCAACACTTAGTGCACCACTCGAAGACGTCGTAAACTCTATCGCTGTTAACAAGATTTGTATCAAGGGTATCTTAGCCACTCCTGACTTCTCTCACACTGGCGAGCTACAGACCCTAAACATGAAGCTCCGTAATGCCCTGGATCTTTACGCTAACGTGGTGCACGTGAAGTCATTGCCCAACGTGAAGTGCAGGCACCAGGACGTGGACTGCATCATCATCAGAGAACAGACCGAAGGAGAGTACTCAGCTTTGGAACATGAATCCGTTCCCGGCGTGGTGGAGTGTTTGAAGATCATCACCGCAGCGAAATCCGAGCGTATCGCGAAATTCGCTTTCGACTACGCCGTGAAGATGGGCCGCAAGAAGGTCACGGCTGTCCACAAGGCCAACATCATGAAGCTGGGCGACGGACTGTTCCTACGCAGCTGCGAGGAGATGGCCAAATTGTACCCTCGCATCCAGTTCGAGAAGATGATCGTGGACAACTGCACGATGCAGATGGTGTCCAACCCGAACCAGTTCGACGTGATGGTGACTCCGAACCTGTACGGGAACATCGTGGACAACCTGGCCAGCGGGCTGGTGGGCGGCGCCGGCGTGGTCGCGGGGGCCTCCTACAGCGCTGACTGCGCGGTCTTCGAACAGGGAGCAAGACACATCTTCTCCGGCGCCGTGGGCAAGAACATCGCGAACCCGACCGCCATGCTGCTCTGCTCCGCCAATCTCCTGGCGCACGTCAACCTGCCGCAGTACTCGAAGATGATCAAGAACGCCATCAATAAAGTTCTGAAAGACGCCAAAGTGCGAACAAAAGATCTTGGCGGTCAGTCCACCACCAAAGACTTCACAAACGCGGTCATTCACAGCCTCTCCTAA

Protein

MSFLSRNIFRAVMQGSQHVGKGVHTSSVTTEKNQPRATKEGRIKCTLIPGDGVGPELVYAVQEVFKAASIPVDFESFFFSEVNPTLSAPLEDVVNSIAVNKICIKGILATPDFSHTGELQTLNMKLRNALDLYANVVHVKSLPNVKCRHQDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKFAFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSNPNQFDVMVTPNLYGNIVDNLASGLVGGAGVVAGASYSADCAVFEQGARHIFSGAVGKNIANPTAMLLCSANLLAHVNLPQYSKMIKNAINKVLKDAKVRTKDLGGQSTTKDFTNAVIHSLS

Similarity

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Uniprot

A0A3S2NDG4   A0A194QCI2   H9JMD4   S4PY54   A0A2H1W5S1   A0A2A4K2Y8   + More
A0A212EJ59   A0A2W1BDC2   A0A0N0PE34   D6X3C9   N6TM86   A0A0T6AU79   U4UM49   A0A2Z5REI6   A0A2J7QDT2   A0A067R3Z8   A0A1B6D7T9   Q29AP6   B4G640   T1PBM5   U4UNX5   A0A2A3E8P5   A0A088ABZ1   A0A1B6FXP9   A0A3B0KB74   A0A182JCX8   A0A0K8U7L4   A0A182PJP3   A0A0A1XFK3   A0A1W4VR89   U5EYC6   A0A084VI48   B4QZC5   B4NHQ8   B4HM75   A0A1Y1KU63   B4PKY9   A0A182JSC9   B3P8P4   Q9VD58   B4JRL0   A0A1B0CS47   T1DQ13   A0A182W7P8   A0A1L8E086   A0A182MZA9   A0A182QPR3   A0A2M3Z6S3   A0A182FNA2   W5JFN5   A0A182M7L5   A0A1Y9HFE0   A0A182XZN3   A0A2M4AJZ5   A0A2M4BRR8   W8BMQ8   A0A182UZ23   A0A182X1H6   A0A182L2J8   Q7Q3A3   A0A182TYG4   A0A182IEF7   A0A023ERZ7   F4WP27   B3LVK6   A0A0L0CR33   A0A0K8TMK2   A0A1S4FPD7   E2BB73   Q16TS5   A0A1I8PE26   A0A195E662   A0A151WM03   A0A154PGB9   A0A0L7RC17   A0A0J7KKC3   A0A195EU14   A0A336K9V2   B4M0N8   A0A0L7KXY3   B4KAP7   A0A0N0BDP8   A0A0C9QMZ8   E2B128   E9IQS1   A0A1J1HY37   A0A232F7A0   A0A195B944   A0A1S3DA33   A0A0M4F6N4   A0A1Q3FYP7   A0A195CN40   K7IP35   A0A224XRZ2   T1HLD4   A0A0P4VMJ1   A0A1A9VAG9   A0A1A9Y0Z7   A0A1B0BMJ9   Q0QHL0  

Pubmed

26354079    19121390    23622113    22118469    28756777    18362917    + More
19820115    23537049    26760975    24845553    15632085    17994087    25315136    25830018    24438588    28004739    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    20920257    23761445    25244985    24495485    20966253    12364791    14747013    17210077    24945155    21719571    26108605    26369729    20798317    17510324    18057021    26227816    21282665    28648823    20075255    27129103    20353571   

EMBL

RSAL01000087    RVE48253.1    KQ459193    KPJ03177.1    BABH01040060    BABH01040061    + More
BABH01040062    GAIX01003883    JAA88677.1    ODYU01006505    SOQ48408.1    NWSH01000220    PCG78264.1    AGBW02014523    OWR41515.1    KZ150431    PZC70900.1    KQ459941    KPJ19165.1    KQ971372    EFA10361.1    APGK01058976    KB741292    ENN70365.1    LJIG01022860    KRT78350.1    KB632383    ERL94192.1    FX983738    BAX07237.1    NEVH01015814    PNF26733.1    KK852714    KDR17889.1    GEDC01015582    JAS21716.1    CM000070    EAL27303.2    CH479179    EDW23805.1    KA645510    AFP60139.1    ERL94193.1    KZ288338    PBC27834.1    GECZ01014802    JAS54967.1    OUUW01000007    SPP82926.1    GDHF01029655    JAI22659.1    GBXI01004576    JAD09716.1    GANO01002083    JAB57788.1    ATLV01013283    KE524849    KFB37642.1    CM000364    EDX13861.1    CH964272    EDW84668.1    CH480815    EDW43123.1    GEZM01075759    JAV63971.1    CM000160    EDW97938.1    CH954182    EDV54208.1    AE014297    BT004877    AAF55942.1    AAO45233.1    ACZ94978.1    CH916373    EDV94400.1    AJWK01025642    GAMD01002849    JAA98741.1    GFDF01001973    JAV12111.1    AXCN02002070    GGFM01003454    MBW24205.1    ADMH02001533    ETN62153.1    AXCM01004662    GGFK01007789    MBW41110.1    GGFJ01006532    MBW55673.1    GAMC01004170    JAC02386.1    AAAB01008964    EAA12327.4    APCN01005201    GAPW01002108    GAPW01002107    JAC11491.1    GL888243    EGI63958.1    CH902617    EDV42576.1    JRES01000142    KNC33874.1    GDAI01002019    JAI15584.1    GL446946    EFN87046.1    CH477641    EAT37918.1    KQ979608    KYN20367.1    KQ982944    KYQ48909.1    KQ434899    KZC10926.1    KQ414617    KOC68306.1    LBMM01006354    KMQ90674.1    KQ981965    KYN31740.1    UFQS01000198    UFQT01000198    SSX01217.1    SSX21597.1    CH940650    EDW67330.1    KRF83249.1    JTDY01004670    KOB67894.1    CH933806    EDW16784.1    KQ435851    KOX70768.1    GBYB01004929    JAG74696.1    GL444771    EFN60601.1    GL764900    EFZ17083.1    CVRI01000021    CRK91446.1    NNAY01000792    OXU26472.1    KQ976542    KYM81056.1    CP012526    ALC47395.1    GFDL01002395    JAV32650.1    KQ977574    KYN01887.1    GFTR01005677    JAW10749.1    ACPB03010980    GDKW01002551    JAI54044.1    JXJN01016973    CCAG010008224    DQ374009    EZ422365    ABG77987.1    ADD18641.1   

Proteomes

UP000283053    UP000053268    UP000005204    UP000218220    UP000007151    UP000053240    + More
UP000007266    UP000019118    UP000030742    UP000235965    UP000027135    UP000001819    UP000008744    UP000095301    UP000242457    UP000005203    UP000268350    UP000075880    UP000075885    UP000192221    UP000030765    UP000000304    UP000007798    UP000001292    UP000002282    UP000075881    UP000008711    UP000000803    UP000001070    UP000092461    UP000075920    UP000075884    UP000075886    UP000069272    UP000000673    UP000075883    UP000075900    UP000076408    UP000075903    UP000076407    UP000075882    UP000007062    UP000075902    UP000075840    UP000007755    UP000007801    UP000037069    UP000008237    UP000008820    UP000095300    UP000078492    UP000075809    UP000076502    UP000053825    UP000036403    UP000078541    UP000008792    UP000037510    UP000009192    UP000053105    UP000000311    UP000183832    UP000215335    UP000078540    UP000079169    UP000092553    UP000078542    UP000002358    UP000015103    UP000078200    UP000092443    UP000092460    UP000092444   

PRIDE

H9JMD4    A0A088ABZ1    Q9VD58   

Pfam

PF00180   Iso_dh

Interpro

IPR004434   Isocitrate_DH_NAD        + More
IPR019818   IsoCit/isopropylmalate_DH_CS       
IPR024084   IsoPropMal-DH-like_dom       

ProteinModelPortal

A0A3S2NDG4   A0A194QCI2   H9JMD4   S4PY54   A0A2H1W5S1   A0A2A4K2Y8   + More
A0A212EJ59   A0A2W1BDC2   A0A0N0PE34   D6X3C9   N6TM86   A0A0T6AU79   U4UM49   A0A2Z5REI6   A0A2J7QDT2   A0A067R3Z8   A0A1B6D7T9   Q29AP6   B4G640   T1PBM5   U4UNX5   A0A2A3E8P5   A0A088ABZ1   A0A1B6FXP9   A0A3B0KB74   A0A182JCX8   A0A0K8U7L4   A0A182PJP3   A0A0A1XFK3   A0A1W4VR89   U5EYC6   A0A084VI48   B4QZC5   B4NHQ8   B4HM75   A0A1Y1KU63   B4PKY9   A0A182JSC9   B3P8P4   Q9VD58   B4JRL0   A0A1B0CS47   T1DQ13   A0A182W7P8   A0A1L8E086   A0A182MZA9   A0A182QPR3   A0A2M3Z6S3   A0A182FNA2   W5JFN5   A0A182M7L5   A0A1Y9HFE0   A0A182XZN3   A0A2M4AJZ5   A0A2M4BRR8   W8BMQ8   A0A182UZ23   A0A182X1H6   A0A182L2J8   Q7Q3A3   A0A182TYG4   A0A182IEF7   A0A023ERZ7   F4WP27   B3LVK6   A0A0L0CR33   A0A0K8TMK2   A0A1S4FPD7   E2BB73   Q16TS5   A0A1I8PE26   A0A195E662   A0A151WM03   A0A154PGB9   A0A0L7RC17   A0A0J7KKC3   A0A195EU14   A0A336K9V2   B4M0N8   A0A0L7KXY3   B4KAP7   A0A0N0BDP8   A0A0C9QMZ8   E2B128   E9IQS1   A0A1J1HY37   A0A232F7A0   A0A195B944   A0A1S3DA33   A0A0M4F6N4   A0A1Q3FYP7   A0A195CN40   K7IP35   A0A224XRZ2   T1HLD4   A0A0P4VMJ1   A0A1A9VAG9   A0A1A9Y0Z7   A0A1B0BMJ9   Q0QHL0  

PDB

5YVT     E-value=5.15455e-85,     Score=801

KEGG

101736806    K00030 isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] | (RefSeq) isocitrate dehydrogenase [NAD] subun

PATHWAY

00020    Citrate cycle (TCA cycle) - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
01210    2-Oxocarboxylic acid metabolism - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0000287   GO:0005739   GO:0006099   GO:0051287   GO:0004449   GO:0016616   GO:0006102   GO:0035072   GO:0005759   GO:0035071   GO:0030117   GO:0006418   GO:0003707   GO:0006281   GO:0006259   GO:0055114  

Subcellular location

Mitochondrion  

Length:

375

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.29235

Exp number, first 60 AAs:

0.00017

Total prob of N-in:

0.00799

outside

1  -  375

 

 

Pi

258.679459

Theta

165.437778

Tajima's D

1.126893

CLR

0.265352

CSRT

0.694765261736913

Interpretation

Uncertain