Gene

KWMTBOMO15624

Pre Gene Modal

BGIBMGA010844

Annotation

PREDICTED:_odorant_receptor_4-like_[Plutella_xylostella]

Location

Bomo_Chr26(+):4460163-4462475      View in EpiBrowser

Full name

Odorant receptor       + More
Odorant receptor 4      

Location in the cell

PlasmaMembrane   Reliability : 4.863

CDS

ATGGCCAAATCCTACAAGATAGTGTATTATCGTCCGATCTATGAGAATTTGATTTATGAGCTACGGGATATGTGGCCGAAGGGCTGCGTTGCCGACGAAGAACATGCAATCATCTGTACAGCCCTCAAACAACTCAATTATGTCGTGCAGGTATTTATAATATGGAGCTTATTTAGGTTACTACTGGTGCACAACGCCCTACTAGTAATATTCCTGTCGCCGCCATTCGTGGAGATCATCAAACAGGTCGCTGGTTGGGACGTTCCTCTGATCCTGCCCTTCTTCTACTGGTTTCCCTTCGACCCGTTCCAGCGAATCTACTACGAAACGATTCTTATCTTTCAAACTTGGCACGGGCTAATTACAATCTGGTTTATGCTGTGCGGAGATTTACTGTTCTGTATATTCTTGAGCCATATTTCGACGCAGTTCGACTTACTGGCAGTGAGGATCAAGAGAATGGTATATGTGCCTGTTGATAAACAGCTAATTGAAGAATACCCTTTGGGTGAGTATCAACGGAGCTAA

Protein

MAKSYKIVYYRPIYENLIYELRDMWPKGCVADEEHAIICTALKQLNYVVQVFIIWSLFRLLLVHNALLVIFLSPPFVEIIKQVAGWDVPLILPFFYWFPFDPFQRIYYETILIFQTWHGLITIWFMLCGDLLFCIFLSHISTQFDLLAVRIKRMVYVPVDKQLIEEYPLGEYQRS

Description

Odorant receptor that specifically recognizes the human odorant sulcatone (6-methylhept-5-en-2-onesul), a volatile odorant emitted at uniquely high levels in humans, thereby playing a key role in mosquito's preference in biting human compared to other animals.

Miscellaneous

Expressed at much higher levels in mosquito strains that preferentially bite human compared to 'ancestral' strains that prefer to bite non-human animals.

Similarity

Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family.
Belongs to the heteromeric odorant receptor channel (TC 1.A.69) family.
Belongs to the transient receptor (TC 1.A.4) family.

Keywords

Complete proteome   Membrane   Olfaction   Polymorphism   Receptor   Reference proteome   Sensory transduction   Transducer   Transmembrane   Transmembrane helix  

Feature

chain  Odorant receptor 4

Uniprot

A0A2H1WMI9   A0A3G6V6Q3   A0A2A4JF91   B7S6U6   A0A2H1V8L9   M1R1W5   + More
A0A194QC90   A0A2L1TG47   A0A0E4B5A7   A0A1V1WCD1   H9JU52   A0A2W1BU51   A0A2A4K396   A0A076E7J5   A0A0P1J1P1   A0A386H997   A0A2K8GKS1   A0A2K8GL45   A0A076E9D1   I3Y3I6   A0A212FA57   A0A3Q9NC10   A0A1Y9TJI5   A0A1S5XXQ9   A0A223HDC2   A0A0V0J0Y1   A0A1B3B724   A0A146JW29   A0A0S1TRB5   A0A0L7LCD2   A0A1B2G2N8   A0A1X9PB26   A0A212ELH4   A0A1B0DM33   Q16NV7   A0A1B0GLR6   A0A1S7UE45   Q16EI9   A0A2K7P6E1   A0A0E4B5I0   A0A386H919   A0A097IYJ9   A0A097ITW8   A0A146JVM3   A0A0B5CMU9   A0A0B5GEY2   A0A0P1IW06   A0A0P1IVT0   A0A2A4K768   A0A0N7MCA4   A0A0K8TVB7   A0A3F2ZDH2   A0A2H1WTJ9   A0A182YJS6   A0A1L2BLA8   H9A5N1   A0A182VQZ4   A0A0N7MCA7   A0A0K8TUR8   A0A182R1K2   A0A076EDF5   A0A386H9C0   A0A0B5GI99   A0A0B5CN07   A0A223HDG1   A0A2K8GKS4   A0A182MBR6   Q6A1K2   A0A3G6V7H7   A0A1S5XXQ5   A0A0P1IW02   A0A076E621   A0A1B3B759   A0A076EDH7   A0A076E9C3   A0A182FQJ2   Q16MN0   A0A1S4FVR6   A0A2A4K114   A0A2A4K9L1   A0A075T619   R4JUT8  

Pubmed

30465940    23679893    26354079    19121390    28756777    24998398    + More
28736530    29375398    22646846    22118469    23950722    28150741    27006164    26812239    26227816    17635615    17510324    25391959    25252791    26017144    25244985    22363688    15289611    25027790    24632377   

EMBL

ODYU01009683    SOQ54285.1    MH193978    AZB49424.1    NWSH01001752    PCG70244.1    + More
EF396285    ABQ84982.1    ODYU01001242    SOQ37185.1    JX999588    AGG08878.1    KQ459193    KPJ03158.1    KY707183    AVF19625.1    LC002728    BAR43476.1    GENK01000082    JAV45831.1    BABH01004087    BABH01004088    KZ149935    PZC77164.1    NWSH01000176    PCG78731.1    KF487664    AII01062.1    LN885129    CUQ99418.1    MG546600    AYD42223.1    KX585336    ARO70229.1    KY225492    ARO70504.1    KF487711    AII01109.1    JQ794816    AFL70821.1    AGBW02009516    OWR50610.1    MH050653    AZT78919.1    KX084480    ARO76435.1    KY399306    AQQ73537.1    KY283727    AST36386.1    GDKB01000059    JAP38437.1    KT588111    AOE48021.1    GEDO01000039    JAP88587.1    KR935708    ALM26200.1    JTDY01001727    KOB73069.1    KU598903    ANZ03149.1    KX084484    ARO76439.1    AGBW02014048    OWR42350.1    AJVK01036856    AJVK01036857    BK006141    CH477806    DAA80356.1    EAT36037.2    AJWK01030596    BK006140    DAA80355.1    KF801614    KF801615    KF801617    KF801618    KF801619    KF801620    KF801621    CH478696    EAT32646.1    LC002721    BAR43469.1    MG546625    AYD42248.1    KM655564    AIT72013.1    KM597226    AIT69903.1    KX084477    GEDO01000063    ARO76432.1    JAP88563.1    KM678326    AJE25899.1    KM892400    AJF23815.1    LN885103    CUQ99392.1    LN885127    CUQ99416.1    NWSH01000058    PCG80087.1    LN885107    CUQ99396.1    GCVX01000215    JAI18015.1    AJWK01027546    ODYU01010558    SOQ55754.1    KT860047    ALS03874.1    JN836681    AFC91721.1    LN885132    CUQ99421.1    GCVX01000214    JAI18016.1    KF487677    AII01075.1    MG546642    AYD42265.1    KM892401    AJF23816.1    KM678327    AJE25900.1    KY283749    AST36408.1    KX585344    ARO70237.1    AXCM01002463    AJ748327    CAG38113.1    MH193980    AZB49426.1    KY399305    AQQ73536.1    LN885105    CUQ99394.1    KF487703    AII01101.1    KT588139    AOE48049.1    KF487702    AII01100.1    KF487701    AII01099.1    BK006143    CH477856    DAA80358.1    EAT35587.2    NWSH01000302    PCG77608.1    NWSH01000040    PCG80352.1    KF768661    AIG51855.1    JX982526    AGK90001.1   

Proteomes

UP000218220    UP000053268    UP000005204    UP000007151    UP000037510    UP000092462    + More
UP000008820    UP000092461    UP000076408    UP000075920    UP000075900    UP000075883    UP000069272   

PRIDE

H9JU52   

Pfam

PF02949   7tm_6        + More
PF00520   Ion_trans
PF12796   Ank_2
PF08344   TRP_2

Interpro

IPR004117   7tm6_olfct_rcpt        + More
IPR013555   TRP_dom       
IPR002153   TRPC_channel       
IPR002110   Ankyrin_rpt       
IPR020683   Ankyrin_rpt-contain_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR005821   Ion_trans_dom       

SUPFAM

SSF48403   SSF48403       

Gene 3D

1.25.40.20    

CDD

cd00204  ANK

ProteinModelPortal

A0A2H1WMI9   A0A3G6V6Q3   A0A2A4JF91   B7S6U6   A0A2H1V8L9   M1R1W5   + More
A0A194QC90   A0A2L1TG47   A0A0E4B5A7   A0A1V1WCD1   H9JU52   A0A2W1BU51   A0A2A4K396   A0A076E7J5   A0A0P1J1P1   A0A386H997   A0A2K8GKS1   A0A2K8GL45   A0A076E9D1   I3Y3I6   A0A212FA57   A0A3Q9NC10   A0A1Y9TJI5   A0A1S5XXQ9   A0A223HDC2   A0A0V0J0Y1   A0A1B3B724   A0A146JW29   A0A0S1TRB5   A0A0L7LCD2   A0A1B2G2N8   A0A1X9PB26   A0A212ELH4   A0A1B0DM33   Q16NV7   A0A1B0GLR6   A0A1S7UE45   Q16EI9   A0A2K7P6E1   A0A0E4B5I0   A0A386H919   A0A097IYJ9   A0A097ITW8   A0A146JVM3   A0A0B5CMU9   A0A0B5GEY2   A0A0P1IW06   A0A0P1IVT0   A0A2A4K768   A0A0N7MCA4   A0A0K8TVB7   A0A3F2ZDH2   A0A2H1WTJ9   A0A182YJS6   A0A1L2BLA8   H9A5N1   A0A182VQZ4   A0A0N7MCA7   A0A0K8TUR8   A0A182R1K2   A0A076EDF5   A0A386H9C0   A0A0B5GI99   A0A0B5CN07   A0A223HDG1   A0A2K8GKS4   A0A182MBR6   Q6A1K2   A0A3G6V7H7   A0A1S5XXQ5   A0A0P1IW02   A0A076E621   A0A1B3B759   A0A076EDH7   A0A076E9C3   A0A182FQJ2   Q16MN0   A0A1S4FVR6   A0A2A4K114   A0A2A4K9L1   A0A075T619   R4JUT8  

KEGG

101738822    K22984 odorant receptor | (RefSeq) odorant receptor 85b-like

GO

GO:0005549   GO:0007165   GO:0016021   GO:0004984   GO:0007608   GO:0005886   GO:0005262   GO:0016020   GO:0020037   GO:0030117   GO:0006418   GO:0003707   GO:0006281   GO:0006259  

PANTHER

PTHR21137   PTHR10117  

Subcellular location

Cell membrane  
Membrane  

Length:

175

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

61.5911

Exp number, first 60 AAs:

10.66653

Total prob of N-in:

0.94603

POSSIBLE N-term signal

sequence

inside

1  -  50

TMhelix

51  -  73

outside

74  -  82

TMhelix

83  -  100

inside

101  -  119

TMhelix

120  -  142

outside

143  -  175

 

 

Pi

198.909469

Theta

159.813285

Tajima's D

0.702966

CLR

0

CSRT

0.572921353932303

Interpretation

Uncertain