Gene

KWMTBOMO15611

Pre Gene Modal

BGIBMGA010837

Annotation

PREDICTED:_equilibrative_nucleoside_transporter_2_isoform_X2_[Papilio_xuthus]

Location

Bomo_Chr26(+):3975599-3983098      View in EpiBrowser

Full name

NADPH-dependent diflavin oxidoreductase 1      

Alternative Name

NADPH-dependent FMN and FAD-containing oxidoreductase

Location in the cell

PlasmaMembrane   Reliability : 4.986

CDS

ATGGTGGACAGCACCGAATGGACACTGACATTCTTCGGACTCACAATAGCATCCGTGTTCTTTTTGAACGCATTCAACGCGGTGTTCCAAAATTCAGTTTACGGTCTGGCCGCGAAGCTCCCGCCCAAATATACCGGTGCCGTGGTCCTGGGCTCCAATATATGTGGAACCCTGGTCGCGATACTGCAGTGGGCTTCTGACATGTTCGGCAACATACGTACATCCGCCATATATTACTTCATCGCTGGAATGTTCGTTCTTCTCATATGCTTCGACACGTATTTCGCATTGCCGCTTAATAGGTTTTATCGTTATCACGATACTCTGCAAGAGAGGACGATGCGAGTGAACCCTGCCCTCGCAGCCACCGATCAGAATTCGAGTCCGAACAAGAGGAGCATACCGTACGGAACGATCTTCGCGCAATCCTGGGTTCAGCTCTACAACATATTCGTTACCTTCTTTGTGACGCTCGCGATCTACCCCGGCTTGCATTCGGAAATTGATCCAGTGACTCCGGGATTTCTCGGTAAAAATTTCGTTTCGATCACGTGCTTTATAACGTTCAACGTGACCGCCATGCTGGGGAACATCACCGCCAGCCTCTGGCAATTTCCTAACAAACGTTGGCTGGCGCTGTTCACGTCGTTACGGTTCCTGTTCATCCCGCTGTACTTCGTGTGCAACTACAAGCCGCTGACGCGCACGCTGCCCGTGCTCGTCCGCGCGGACTGGGCCTACTGGCTCATCGCCGTGCTGTTCGGCTGGAGCTCGGGCCACGGCAGCAGCCTGGGGATGATGTACGTCAGCGGCACGGTGTCCCCGGAGCACGCGTCCACTGCGGGCATGGTGGGCGGCGCCATGCTCGTCACCGGCATCGTGTCGGGGATCACCTTCAGCTGGTTGTGTCCGCTCGTCGTCACCATGGACTTATGGAAGAGCATCTAG

Protein

MVDSTEWTLTFFGLTIASVFFLNAFNAVFQNSVYGLAAKLPPKYTGAVVLGSNICGTLVAILQWASDMFGNIRTSAIYYFIAGMFVLLICFDTYFALPLNRFYRYHDTLQERTMRVNPALAATDQNSSPNKRSIPYGTIFAQSWVQLYNIFVTFFVTLAIYPGLHSEIDPVTPGFLGKNFVSITCFITFNVTAMLGNITASLWQFPNKRWLALFTSLRFLFIPLYFVCNYKPLTRTLPVLVRADWAYWLIAVLFGWSSGHGSSLGMMYVSGTVSPEHASTAGMVGGAMLVTGIVSGITFSWLCPLVVTMDLWKSI

Description

Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog.

Cofactor

FAD
FMN

Similarity

Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
In the N-terminal section; belongs to the flavodoxin family.

Uniprot

H9JMT4   A0A194PL39   S4PKB3   A0A3S2NQK3   A0A212EYJ3   A0A2H1VT64   + More
A0A2A4IY39   A0A194RQE1   U5EVT7   B0WGR4   A0A182LWW1   A0A182T552   A0A182Q2X6   W8C2Y0   A0A084WQY1   A0A182XX87   A0A182RBV4   A0A182PBD6   Q17A37   A0A1B0AKG2   A0A182LAE8   A0A182TDX6   Q7PTI1   A0A182I8J1   A0A1S4FAG4   A0A182WYG2   A0A182VQC5   A0A0A1WII1   A0A182N6W6   A0A023EQ24   A0A182IXK0   A0A0K8TKS5   N6TY64   A0A182GFQ3   A0A023EU60   A0A2M4CNL3   A0A164QX20   A0A2M4API6   A0A1B6JU47   A0A182F8G7   A0A2M4BN03   A0A1Q3FFA0   W5JEI8   A0A0P6H3N9   A0A0P5T7Y4   A0A2A3E229   A0A151X4G1   A0A0C9QPL1   A0A2M4BKX5   A0A1Q3FFH8   A0A1Q3FFC7   A0A2M3Z0Z8   A0A2M4CHE9   A0A1B6DIQ1   A0A0P5VMK4   A0A0P5TUS5   E9FRB5   A0A0P6BJ91   A0A0P5A9T3   A0A2M4BL33   K7INK5   A0A0M4E6X9   E2BV50   A0A1B0CMU0   A0A1W4UNU7   A0A195BLH5   A0A087ZWM1   A0A0L7R2K6   A0A1B6FRU4   A0A1L8DE44   B3MNZ1   A0A1L8DE59   A0A1L8DEF8   A0A195CNP2   A0A1L8DEK0   A0A0P4YWH3   F4WII4   D6X319   A0A1L8DEI1   A0A1A9VM26   B4P0B7   A0A1L8DEI3   A0A1B6LYW3   A0A151J0K3   A0A1B6M312   E9J590   A0A0T6AWR2   A0A154PJX0   A0A224XFF7   A0A023F3B9   A0A1B0AHH1   A0A2H8TQU0   A0A232EU38   A0A1D2N3U1   A0A336MBT2   A0A336MEK9   B3N5T5   A0A026WZJ9   A0A3L8DRB1   E0W0A7  

EC Number

1.18.1.-

Pubmed

19121390    26354079    23622113    22118469    24495485    24438588    + More
25244985    17510324    20966253    12364791    14747013    17210077    25830018    24945155    26369729    23537049    26483478    20920257    23761445    21292972    20075255    20798317    17994087    21719571    18362917    19820115    17550304    21282665    25474469    28648823    27289101    24508170    30249741    20566863   

EMBL

BABH01016835    BABH01016836    BABH01016837    KQ459601    KPI93713.1    GAIX01004595    + More
JAA87965.1    RSAL01000010    RVE53678.1    AGBW02011486    OWR46568.1    ODYU01004307    SOQ44035.1    NWSH01005651    PCG64080.1    KQ459875    KPJ19619.1    GANO01000868    JAB59003.1    DS231928    EDS27140.1    AXCM01004381    AXCN02000310    GAMC01002968    GAMC01002967    JAC03589.1    ATLV01025806    ATLV01025807    ATLV01025808    KE525400    KFB52625.1    CH477340    EAT43127.1    JXJN01025262    AAAB01008805    EAA03890.5    APCN01003039    GBXI01015600    GBXI01002505    JAC98691.1    JAD11787.1    GAPW01001946    JAC11652.1    GDAI01002679    JAI14924.1    APGK01050299    APGK01050300    APGK01050301    KB741169    KB632294    ENN73321.1    ERL91679.1    JXUM01060047    KQ562084    KXJ76728.1    GAPW01001136    JAC12462.1    GGFL01002671    MBW66849.1    LRGB01002325    KZS08136.1    GGFK01009384    MBW42705.1    GECU01005024    JAT02683.1    GGFJ01005294    MBW54435.1    GFDL01008817    JAV26228.1    ADMH02001471    ETN62466.1    GDIQ01024555    JAN70182.1    GDIP01184235    GDIQ01245006    GDIP01131390    JAK06719.1    JAL72324.1    KZ288438    PBC25745.1    KQ982557    KYQ55108.1    GBYB01002622    JAG72389.1    GGFJ01004564    MBW53705.1    GFDL01008783    JAV26262.1    GFDL01008802    JAV26243.1    GGFM01001434    MBW22185.1    GGFL01000555    MBW64733.1    GEDC01011732    JAS25566.1    GDIP01099201    JAM04514.1    GDIP01139300    JAL64414.1    GL732523    EFX90137.1    GDIP01015037    JAM88678.1    GDIP01202133    JAJ21269.1    GGFJ01004563    MBW53704.1    CP012523    ALC38415.1    GL450810    EFN80440.1    AJWK01019162    AJWK01019163    AJWK01019164    AJWK01019165    KQ976440    KYM86553.1    KQ414666    KOC65069.1    GECZ01016861    JAS52908.1    GFDF01009345    JAV04739.1    CH902620    EDV32178.1    GFDF01009343    JAV04741.1    GFDF01009344    JAV04740.1    KQ977580    KYN01719.1    GFDF01009213    JAV04871.1    GDIP01222640    JAJ00762.1    GL888175    EGI66115.1    KQ971372    EFA10308.1    GFDF01009211    JAV04873.1    CM000157    EDW87875.1    GFDF01009212    JAV04872.1    GEBQ01011101    JAT28876.1    KQ980624    KYN15035.1    GEBQ01009661    JAT30316.1    GL768124    EFZ12035.1    LJIG01022679    KRT79285.1    KQ434938    KZC12156.1    GFTR01006662    JAW09764.1    GBBI01002939    JAC15773.1    GFXV01004177    MBW15982.1    NNAY01002170    OXU21879.1    LJIJ01000245    ODM99939.1    UFQT01000883    SSX27822.1    SSX27821.1    CH954177    EDV59094.1    KK107063    EZA61258.1    QOIP01000005    RLU22974.1    DS235858    EEB19063.1   

Proteomes

UP000005204    UP000053268    UP000283053    UP000007151    UP000218220    UP000053240    + More
UP000002320    UP000075883    UP000075901    UP000075886    UP000030765    UP000076408    UP000075900    UP000075885    UP000008820    UP000092460    UP000075882    UP000075902    UP000007062    UP000075840    UP000076407    UP000075920    UP000075884    UP000075880    UP000019118    UP000030742    UP000069940    UP000249989    UP000076858    UP000069272    UP000000673    UP000242457    UP000075809    UP000000305    UP000002358    UP000092553    UP000008237    UP000092461    UP000192221    UP000078540    UP000005203    UP000053825    UP000007801    UP000078542    UP000007755    UP000007266    UP000078200    UP000002282    UP000078492    UP000076502    UP000092445    UP000215335    UP000094527    UP000008711    UP000053097    UP000279307    UP000009046   

PRIDE

H9JMT4   

Pfam

PF01733   Nucleoside_tran        + More
PF00175   NAD_binding_1
PF00258   Flavodoxin_1
PF00667   FAD_binding_1

Interpro

IPR002259   Eqnu_transpt        + More
IPR036259   MFS_trans_sf       
IPR020846   MFS_dom       
IPR023173   NADPH_Cyt_P450_Rdtase_alpha       
IPR028879   NDOR1       
IPR039261   FNR_nucleotide-bd       
IPR003097   CysJ-like_FAD-binding       
IPR017938   Riboflavin_synthase-like_b-brl       
IPR008254   Flavodoxin/NO_synth       
IPR001433   OxRdtase_FAD/NAD-bd       
IPR017927   FAD-bd_FR_type       
IPR029039   Flavoprotein-like_sf       
IPR001094   Flavdoxin-like       
IPR001709   Flavoprot_Pyr_Nucl_cyt_Rdtase       

SUPFAM

SSF103473   SSF103473        + More
SSF52218   SSF52218       
SSF63380   SSF63380       
SSF52343   SSF52343       

Gene 3D

1.20.990.10     3.40.50.360     3.40.50.80    

CDD

cd06174  MFS

ProteinModelPortal

H9JMT4   A0A194PL39   S4PKB3   A0A3S2NQK3   A0A212EYJ3   A0A2H1VT64   + More
A0A2A4IY39   A0A194RQE1   U5EVT7   B0WGR4   A0A182LWW1   A0A182T552   A0A182Q2X6   W8C2Y0   A0A084WQY1   A0A182XX87   A0A182RBV4   A0A182PBD6   Q17A37   A0A1B0AKG2   A0A182LAE8   A0A182TDX6   Q7PTI1   A0A182I8J1   A0A1S4FAG4   A0A182WYG2   A0A182VQC5   A0A0A1WII1   A0A182N6W6   A0A023EQ24   A0A182IXK0   A0A0K8TKS5   N6TY64   A0A182GFQ3   A0A023EU60   A0A2M4CNL3   A0A164QX20   A0A2M4API6   A0A1B6JU47   A0A182F8G7   A0A2M4BN03   A0A1Q3FFA0   W5JEI8   A0A0P6H3N9   A0A0P5T7Y4   A0A2A3E229   A0A151X4G1   A0A0C9QPL1   A0A2M4BKX5   A0A1Q3FFH8   A0A1Q3FFC7   A0A2M3Z0Z8   A0A2M4CHE9   A0A1B6DIQ1   A0A0P5VMK4   A0A0P5TUS5   E9FRB5   A0A0P6BJ91   A0A0P5A9T3   A0A2M4BL33   K7INK5   A0A0M4E6X9   E2BV50   A0A1B0CMU0   A0A1W4UNU7   A0A195BLH5   A0A087ZWM1   A0A0L7R2K6   A0A1B6FRU4   A0A1L8DE44   B3MNZ1   A0A1L8DE59   A0A1L8DEF8   A0A195CNP2   A0A1L8DEK0   A0A0P4YWH3   F4WII4   D6X319   A0A1L8DEI1   A0A1A9VM26   B4P0B7   A0A1L8DEI3   A0A1B6LYW3   A0A151J0K3   A0A1B6M312   E9J590   A0A0T6AWR2   A0A154PJX0   A0A224XFF7   A0A023F3B9   A0A1B0AHH1   A0A2H8TQU0   A0A232EU38   A0A1D2N3U1   A0A336MBT2   A0A336MEK9   B3N5T5   A0A026WZJ9   A0A3L8DRB1   E0W0A7  

KEGG

101741989    K15014 solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3 | (RefSeq) equi

GO

GO:0016021   GO:0005337   GO:0005886   GO:0007268   GO:0090281   GO:0008306   GO:0050661   GO:0050660   GO:0016226   GO:0003958   GO:0010181   GO:0005737   GO:0006810   GO:0046872   GO:0030126   GO:0030117   GO:0006418   GO:0003707   GO:0006281   GO:0006259   GO:1901642  

PANTHER

PTHR10332  

Subcellular location

Cytoplasm  

Length:

315

Number of predicted TMHs:

8

Exp number of AAs in TMHs:

175.48843

Exp number, first 60 AAs:

39.74153

Total prob of N-in:

0.97249

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  29

outside

30  -  43

TMhelix

44  -  62

inside

63  -  74

TMhelix

75  -  97

outside

98  -  143

TMhelix

144  -  166

inside

167  -  178

TMhelix

179  -  201

outside

202  -  210

TMhelix

211  -  233

inside

234  -  245

TMhelix

246  -  268

outside

269  -  282

TMhelix

283  -  305

inside

306  -  315

 

 

Pi

192.954057

Theta

148.044558

Tajima's D

0.976648

CLR

0.00097

CSRT

0.657667116644168

Interpretation

Uncertain