Gene

KWMTBOMO15610

Pre Gene Modal

BGIBMGA010837

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_equilibrative_nucleoside_transporter_1_[Papilio_machaon]

Location

Bomo_Chr26(+):3945969-3974633      View in EpiBrowser

Full name

NADPH-dependent diflavin oxidoreductase 1      

Alternative Name

NADPH-dependent FMN and FAD-containing oxidoreductase

Location in the cell

PlasmaMembrane   Reliability : 2.292

CDS

ATGGAGATGAGCCATCAAGGTGGGGCGGAGGCCGAGAGCCTCCTAAGACATGACCAGAGGAGCGCCATCGTCATGCCCGGCCAGCGGACTGGACGCTGGGAGGATGGCGAGAAGGCTCCGTTCCTACGTAACGAGCCGGTGAAACTGACACCCGCTTGGGAGGCCACGAACCTGCCCAATGACACGCTCAACTTGAAAGGTATAGCAATGGACCTGACTCCGCCGAAAGATAAATGGAACCTCATTTATCTGACGTTGGTGCTTCACGGCTTGGGAACGCTGACCGCCTGGAACATGTTCATAACAGCGAAAGCGTACTTTGAGACGTACAAACTCGCCTCGGAGCCGGCCTTGTCCGAGAACTTCCTCACGTACATCGGCTGGGCGAGTCAGATACCGAATTTGCTGTTCAGCTGGTTTAATATATTTTTCCAATTGGGGTATGTTAATTTTTTTTTATTTTTTATTGTTTAG

Protein

MEMSHQGGAEAESLLRHDQRSAIVMPGQRTGRWEDGEKAPFLRNEPVKLTPAWEATNLPNDTLNLKGIAMDLTPPKDKWNLIYLTLVLHGLGTLTAWNMFITAKAYFETYKLASEPALSENFLTYIGWASQIPNLLFSWFNIFFQLGYVNFFLFFIV

Description

Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog.

Cofactor

FAD
FMN

Similarity

Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
In the N-terminal section; belongs to the flavodoxin family.

Uniprot

A0A194PL39   H9JMT4   S4PKB3   A0A212EYJ3   A0A3S2NQK3   A0A194RQE1   + More
A0A023EU60   A0A1S4FAG4   A0A336MBT2   A0A1Q3FFC7   A0A1Q3FFH8   A0A1B6JU47   A0A1B6FRU4   A0A1B6DIQ1   A0A336MEK9   A0A1B6LYW3   A0A182VQC5   B0WGR4   A0A1L8DEK0   A0A1L8DEI1   A0A1L8DEI3   A0A182LWW1   A0A1B6M312   A0A1B0CMU0   A0A023F3B9   A0A224XFF7   A0A0K8TKS5   A0A1B0AKG2   A0A182IXK0   A0A182N6W6   A0A1A9VM26   A0A164I0D6   A0A182RBV4   A0A146MH54   A0A0A9WT49   A0A0K8SUD5   A0A3Q0J2I2   A0A195F335   A0A182TDX6   Q7PTI1   A0A0J7L8Y2   A0A182K078   A0A182LAE8   A0A182XX87   U5EVT7   A0A2R7VPU9   A0A182Q2X6   A0A1I8PKL2   E2BV50   A0A0P6H3N9   A0A0P4YWH3   A0A1J1HM94   A0A151J0K3   A0A0P5A9T3   T1HNN9   A0A0P6BJ91   T1EAP4   A0A2M4CHE9   A0A0M9A978   A0A182F8G7   V9I984   A0A2M4BKX5   A0A0L7R2K6   T1PI77   A0A2M4BL33   A0A154PJX0   A0A158NZY4   A0A2A3E229   A0A087ZWM1   A0A195CNP2   A0A151X4G1   A0A026WZJ9   A0A182PBD6   E9FRB5   A0A3L8DRB1   F4WII4   A0A2J7PI52   A0A2J7PI60   E9J590   A0A310SI93   A0A084WQY1   K7INK5   A0A182I8J1   A0A182WYG2   A0A067R482   A0A232EU38   A0A1Y1LTG1   J9K041   D6X319   A0A2S2QTU9   A0A0C9R913   A0A2T7PBP1   A0A0T6AWR2   A0A1B6FGI1   E0W0A7  

EC Number

1.18.1.-

Pubmed

26354079    19121390    23622113    22118469    24945155    25474469    + More
26369729    26823975    25401762    12364791    14747013    17210077    20966253    25244985    20798317    25315136    21347285    24508170    21292972    30249741    21719571    21282665    24438588    20075255    24845553    28648823    28004739    18362917    19820115    20566863   

EMBL

KQ459601    KPI93713.1    BABH01016835    BABH01016836    BABH01016837    GAIX01004595    + More
JAA87965.1    AGBW02011486    OWR46568.1    RSAL01000010    RVE53678.1    KQ459875    KPJ19619.1    GAPW01001136    JAC12462.1    UFQT01000883    SSX27822.1    GFDL01008802    JAV26243.1    GFDL01008783    JAV26262.1    GECU01005024    JAT02683.1    GECZ01016861    JAS52908.1    GEDC01011732    JAS25566.1    SSX27821.1    GEBQ01011101    JAT28876.1    DS231928    EDS27140.1    GFDF01009213    JAV04871.1    GFDF01009211    JAV04873.1    GFDF01009212    JAV04872.1    AXCM01004381    GEBQ01009661    JAT30316.1    AJWK01019162    AJWK01019163    AJWK01019164    AJWK01019165    GBBI01002939    JAC15773.1    GFTR01006662    JAW09764.1    GDAI01002679    JAI14924.1    JXJN01025262    LRGB01008684    KZS00747.1    GDHC01020303    GDHC01000352    JAP98325.1    JAQ18277.1    GBHO01035571    GBHO01035569    GBHO01035568    GBHO01035567    JAG08033.1    JAG08035.1    JAG08036.1    JAG08037.1    GBRD01008898    JAG56923.1    KQ981856    KYN34592.1    AAAB01008805    EAA03890.5    LBMM01000214    KMR04460.1    GANO01000868    JAB59003.1    KK854007    PTY09168.1    AXCN02000310    GL450810    EFN80440.1    GDIQ01024555    JAN70182.1    GDIP01222640    JAJ00762.1    CVRI01000008    CRK88524.1    KQ980624    KYN15035.1    GDIP01202133    JAJ21269.1    ACPB03007647    GDIP01015037    JAM88678.1    GAMD01000232    JAB01359.1    GGFL01000555    MBW64733.1    KQ435721    KOX78523.1    JR037241    AEY57658.1    GGFJ01004564    MBW53705.1    KQ414666    KOC65069.1    KA647618    AFP62247.1    GGFJ01004563    MBW53704.1    KQ434938    KZC12156.1    ADTU01005131    ADTU01005132    KZ288438    PBC25745.1    KQ977580    KYN01719.1    KQ982557    KYQ55108.1    KK107063    EZA61258.1    GL732523    EFX90137.1    QOIP01000005    RLU22974.1    GL888175    EGI66115.1    NEVH01025129    PNF16026.1    PNF16025.1    GL768124    EFZ12035.1    KQ768431    OAD53172.1    ATLV01025806    ATLV01025807    ATLV01025808    KE525400    KFB52625.1    APCN01003039    KK852766    KDR16974.1    NNAY01002170    OXU21879.1    GEZM01050427    JAV75590.1    ABLF02024980    KQ971372    EFA10308.1    GGMS01011951    MBY81154.1    GBYB01009342    JAG79109.1    PZQS01000005    PVD30835.1    LJIG01022679    KRT79285.1    GECZ01020457    JAS49312.1    DS235858    EEB19063.1   

Proteomes

UP000053268    UP000005204    UP000007151    UP000283053    UP000053240    UP000075920    + More
UP000002320    UP000075883    UP000092461    UP000092460    UP000075880    UP000075884    UP000078200    UP000076858    UP000075900    UP000079169    UP000078541    UP000075902    UP000007062    UP000036403    UP000075881    UP000075882    UP000076408    UP000075886    UP000095300    UP000008237    UP000183832    UP000078492    UP000015103    UP000053105    UP000069272    UP000053825    UP000095301    UP000076502    UP000005205    UP000242457    UP000005203    UP000078542    UP000075809    UP000053097    UP000075885    UP000000305    UP000279307    UP000007755    UP000235965    UP000030765    UP000002358    UP000075840    UP000076407    UP000027135    UP000215335    UP000007819    UP000007266    UP000245119    UP000009046   

PRIDE

H9JMT4   

Pfam

PF01733   Nucleoside_tran        + More
PF08952   DUF1866
PF03372   Exo_endo_phos
PF02383   Syja_N
PF00175   NAD_binding_1
PF00258   Flavodoxin_1
PF00667   FAD_binding_1

Interpro

IPR002259   Eqnu_transpt        + More
IPR036259   MFS_trans_sf       
IPR000300   IPPc       
IPR002013   SAC_dom       
IPR015047   DUF1866       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR034972   SYNJ1       
IPR020846   MFS_dom       
IPR023173   NADPH_Cyt_P450_Rdtase_alpha       
IPR028879   NDOR1       
IPR039261   FNR_nucleotide-bd       
IPR003097   CysJ-like_FAD-binding       
IPR017938   Riboflavin_synthase-like_b-brl       
IPR008254   Flavodoxin/NO_synth       
IPR001433   OxRdtase_FAD/NAD-bd       
IPR017927   FAD-bd_FR_type       
IPR029039   Flavoprotein-like_sf       
IPR001094   Flavdoxin-like       
IPR001709   Flavoprot_Pyr_Nucl_cyt_Rdtase       

SUPFAM

SSF103473   SSF103473        + More
SSF56219   SSF56219       
SSF52218   SSF52218       
SSF63380   SSF63380       
SSF52343   SSF52343       

Gene 3D

3.60.10.10     1.20.990.10     3.40.50.360     3.40.50.80    

CDD

cd06174  MFS

ProteinModelPortal

A0A194PL39   H9JMT4   S4PKB3   A0A212EYJ3   A0A3S2NQK3   A0A194RQE1   + More
A0A023EU60   A0A1S4FAG4   A0A336MBT2   A0A1Q3FFC7   A0A1Q3FFH8   A0A1B6JU47   A0A1B6FRU4   A0A1B6DIQ1   A0A336MEK9   A0A1B6LYW3   A0A182VQC5   B0WGR4   A0A1L8DEK0   A0A1L8DEI1   A0A1L8DEI3   A0A182LWW1   A0A1B6M312   A0A1B0CMU0   A0A023F3B9   A0A224XFF7   A0A0K8TKS5   A0A1B0AKG2   A0A182IXK0   A0A182N6W6   A0A1A9VM26   A0A164I0D6   A0A182RBV4   A0A146MH54   A0A0A9WT49   A0A0K8SUD5   A0A3Q0J2I2   A0A195F335   A0A182TDX6   Q7PTI1   A0A0J7L8Y2   A0A182K078   A0A182LAE8   A0A182XX87   U5EVT7   A0A2R7VPU9   A0A182Q2X6   A0A1I8PKL2   E2BV50   A0A0P6H3N9   A0A0P4YWH3   A0A1J1HM94   A0A151J0K3   A0A0P5A9T3   T1HNN9   A0A0P6BJ91   T1EAP4   A0A2M4CHE9   A0A0M9A978   A0A182F8G7   V9I984   A0A2M4BKX5   A0A0L7R2K6   T1PI77   A0A2M4BL33   A0A154PJX0   A0A158NZY4   A0A2A3E229   A0A087ZWM1   A0A195CNP2   A0A151X4G1   A0A026WZJ9   A0A182PBD6   E9FRB5   A0A3L8DRB1   F4WII4   A0A2J7PI52   A0A2J7PI60   E9J590   A0A310SI93   A0A084WQY1   K7INK5   A0A182I8J1   A0A182WYG2   A0A067R482   A0A232EU38   A0A1Y1LTG1   J9K041   D6X319   A0A2S2QTU9   A0A0C9R913   A0A2T7PBP1   A0A0T6AWR2   A0A1B6FGI1   E0W0A7  

KEGG

101741989    K15014 solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3 | (RefSeq) equi

GO

GO:0016021   GO:0005337   GO:0005886   GO:0046856   GO:0042578   GO:0050661   GO:0050660   GO:0016226   GO:0003958   GO:0010181   GO:0005737  

PANTHER

PTHR10332   PTHR11200:SF158  

Subcellular location

Cytoplasm  

Length:

157

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

44.34927

Exp number, first 60 AAs:

0

Total prob of N-in:

0.67293

outside

1  -  78

TMhelix

79  -  101

inside

102  -  133

TMhelix

134  -  156

outside

157  -  157

 

 

Pi

212.974639

Theta

166.284062

Tajima's D

0.915673

CLR

0.097905

CSRT

0.632018399080046

Interpretation

Uncertain