Gene

KWMTBOMO15591

Pre Gene Modal

BGIBMGA010830

Annotation

PREDICTED:_disintegrin_and_metalloproteinase_domain-containing_protein_12_[Bombyx_mori]

Location

Bomo_Chr26(+):3629039-3652941      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 3.978

CDS

ATGTACGATCACACGGATTTACACACGAACTACAACTGCGGGTATCATGGTGGTGTGACCAACAACAGTAATTACGACCCCGAGCTGTATCACAAATACCAAAAGGGCGAGGAGTTGAGCCGGACTAGAGTTGCCAGGTACAAAAGGAGCACTGACGACAATCAAGTACGCGAGCCCTTCAACGCGAACACGCTGTCGCGTTACGTGGAGCTTGTCCTCGTCGTCGACAACAAGGAGTTCAAAGCGAACCACGGAAACCTGCGAGCTGTGTACCAACAGATAAAGGACGTGGCGAACATCATTAACTCTGTCTATGCTCCACTGAACATATTCATAGCTCTAGTCGGAGTAGAGGTTTGGACGGAAAGAGACGAAATACAATTAGAGGAGGACGGCGATGAAACGTTGAAGCATTTCTTGCACTACCGGAGAACGACTCTACTAAGAGAAGTGCCCAATGACAACGCGCATTTGTTAACTCGGCAGGCGTTCAAAGACGGCGTCGTCGGTAAAGCGCTAAAAGGGCCGATATGTACGTACGAGTTCTCCGGCGGCGTGGCCACGAATCACTCTGAGGTGCTGGGCCTGGTGGCCACGACCATAGCCCACGAGATGGGCCACAACTTCGGCATAGAGCACGACACGGAGGAGCACTGCGAGTGTCCAGACGAGAAGTGTATCATGAGTCCGTCCAGCACTTCGGTAATCCCGGTCCGGTGGTCGTCGTGCAGCCTCAAGTCGCTGGCGCTCTCTTTCGAACGAGGAATGGACTACTGTCTGAGGAACAAGCCTCGTCGTTTATTCCAATCTCCGACGTGCGGCAACGGCTTCATCGAGCCCGGCGAGCAGTGCGACTGCGGGATGACGCCGGACCGGAGCGGCAGGAGCGACTGCCACCGCTGCTGCCACCCCACGACGTGCATGCTGCGTGCCAATGCGACGTGCGGCGCGGGGACCTGCTGCGATCTGCAGACTTGCCGACCCAAGTCAGCGGGGACGGTGTGTCGGAGATCGGAGAAGGAGTGCGACCTCCCGGAGTACTGCACCGGGCAGTCCGAGTTCTGTCCGGACGACGTTTACAAGATGGACACCATACCGTGCAACCATGGACAGGCGTACTGCGTGAAGGGCTCTTGCCGCTCGCACACGGACCAGTGCCGGCTGCTGTGGGGCGTCACCGGGGAGAGCTCGCACGACAAGTGCTACATGTCAGCCAACGTCAAAGGGAACAAGAACGGCAACTGCGGCTACATCCGCCCCGCCCAGCGGTACGTGCCGTGCGCTTACGAGGACGCGCGCTGCGGCCTGCTGCAGTGCAGACACCTCAATGAGAAGCTGGAGTTCGGCATGGACTCGGTGGCGGCCGTCTCGGCGGTTTTCATCAACAATAACGGTACGATAATACCGTGCCGGACGGCCATCATCGATTTGGGACTGGGAGACGTTGATCCCGGCCTCGTGCCCGACGGAGCCGCCTGCGGGGAGCACAAGATGTGCTTGAAACAAAGGTGCGTGTCCGTTGAGTCCGTCCGGGAGACGATAGTCAACAAGCACTCGTCGATCTGCCCGTCCAACTGTTCCGGGCACGGCGTCTGTAACTCCGAGGGTCACTGTCACTGTGAAGCCGGATTCGCGCCGCCACTGTGTGCCTTGCCCGGCCCTGGTGGCTCCGTGGACTCCGGTCCGGCCACTGACCCGACCATCCAAAGGAACTTCATGGTCGCGATGTACGTGATCTTCCTCGGCATCATACCGTCGGTTCTGCTCGTCATGTTCCTCGTGTACTACTCGAGACACAACGTGCTGTACTGGTGGAAGAAACCACGGAAATCGTCTCCGTCACCGAAGAAAGCGAGCCTCCAGCACCGGATATCGCGGAGTGCAAGCAAATTCGCTGCCAATTTCCAAAATGGCCCCCAGAACGGTGCCCAGCCCGTCGTGCATACGCCTTCGAACCCGGACGACATGAGCTCCAGCCTCCTGAGAAGCGATTCCGACAGGAACCCGTCAGGTAACATCAACCCATCCGTCAATTTCTTCGGAAACTTCAAAGGTTTCACGTTAACGCCCATAGAGAAGTCTCAAGACGCCACCGACAAGAGCGAGGTTGACGCGAAGACTGTCAAGACTGCTGCGGAATCTAAAAGCGCAAAGATCACGCCGGTACATCGCAGCAGTAGCAACAGTCAGAGCTTAATGAATCAAGGAGTTTTGAAGTCCACGTTACGAGCAGCCCCGCCCCTACCCGTCGTCCCGGCTGCGGCGAAAACCAGTCCGGCAACAAGCCCGGCCGTCAAAAGAACGAACAGTTCGGTACAAAACAGGATAAAAGCTTTAATGACCGCAGAGAAACCGGAGGAAACTCCTGTTAATCCACCGTCCCGGCCAGTCATATCCAGTCCTATACTGGAAGCTTCCACTTGTACTGCGAAAGAATTGATATCTCCGCTGCAGGGATCCAAAACTTTAGGTCCGATAAGGGCAGCGCCTACAGTGCCGAGCGCGTCACCAGATTTCCCTACAAGGCCCTTAAGCATGCACTCAGCCAGCAGCGTGCTCCAAAAACCCCTACCGGAAGAGCCTAAAAGGGTCAAAGAAGGAATATCGCTAAACCGCATCGCTTCATTCTTGAAACAAGACAAGCCTAAAGAAAAAGAACGGAATCCCGTTGAGAGAAGTCACTCTCTGCCCAAAAACCAGAACCATCAGATTAAAGTGGCTCTAAGGAATTTACAAATCTCGAAGCCTATTCCGCAGACAGAGATCGAATTGCCAGTCGGTGCTGTTTCCGTTGTCTCCGATTCTGAAGACGAAGACTCTAAAGCATTCGTGAACAGAGCTCAAAGCATGAGAGCCCCGCAGGCTCAGAAGCCGACTATACAAAGTTTTGGTTCAATGAGGCAGGCGCCCGGGGTTCAACGACCTGTCTCGATAGTGGGCAGGCCGACCGCACCGCCGCCACCATTGCCACCGCAAACCGAACCCAACGCCAACCAAACTAACTTCCCCATTGAAAACAAATCTGTAGACTACGTTGATTGCATTGAAGAGAAGCAGGCTCCTCTAGCCGATATAAACGAAGAGTCTCCCGACAATATATACGCGATCATCGAAGAAAGTCCCGAGAGTCATTCGAAGCCAATACCGCCTCCCACTTCGACCATACCGCAGCCGAACTCCGGAAGTTCGGAGAGCATGGGCTTACTGGGAGAGATAGTTAACGAAATACAAAACCGGAATCTCGAATCGATATATTCGGTATCGACACTGAAAAGGAAGCAGAAGGATCGAAAAGAGAAGGAGGGCTCTAATCGAGACAGCACGTACACGAACTCAGAGCACTACAAGACGCCTGAGAGCGTGTATAGTAACTCCGGAGCGAAGTCGACAGTTTCGACAACAAGCAGCGGGTATCTACTGCCGTCAGCTGTGAACGTACCGAATTTTGTAACCAAAGATACAGGAGAGGTCACCGACAGTGAGAAAGCACCTCCCTCGCCCACTCTGAAGGGAGGGCCAAACTCGAAAATCCCTACATTCTCGCGCCAAGTGACACCGCCCGGCTTAAAAACATTCAGAAACGCAACGCCTTCACCGAAAAGTACCCTGAAGAACGCTCATTTATCCACCAAAATATCGAACAGTCCAGATTTAGTTTCGAGCTGTAACGTACCAGAGACGAAGAACAAGACTCCAGACGTAATCAACAATAATAAAATACCAAACGAAGCGCCTAAAGTTGCGACGAAGCCCGCGGTGACGGCCAAACCAGTTGACAACAGACCGCCTCTAAAACAAGGCCCGAACGCAGACAAAAAACTCTCGGCCAAAACAAATCAGCCATTGAAACCTGTTAATTCATCGTCAAACTTGAACAAAACCGTAGAAAAGAATCCGCCCTTGAATCGTGCCAATTCTAAACTAGAGAATAATGTTAAATCTATAGCAGATAGTTTGAACAAGAATAAGCCTAAAGTAGTACCTAAGCCCACGACCCTGGTGAACAAAACCGAATCCACTGTCAAACCAAATTCCACTAAATTGACAGCGAAGCCCTCAAATGTTGCCAGTTTGCAGCAAAAGTTCGAAAATAGAAAATCTATAGGCAAAGAGATCAATGTAAGAAAATAG

Protein

MYDHTDLHTNYNCGYHGGVTNNSNYDPELYHKYQKGEELSRTRVARYKRSTDDNQVREPFNANTLSRYVELVLVVDNKEFKANHGNLRAVYQQIKDVANIINSVYAPLNIFIALVGVEVWTERDEIQLEEDGDETLKHFLHYRRTTLLREVPNDNAHLLTRQAFKDGVVGKALKGPICTYEFSGGVATNHSEVLGLVATTIAHEMGHNFGIEHDTEEHCECPDEKCIMSPSSTSVIPVRWSSCSLKSLALSFERGMDYCLRNKPRRLFQSPTCGNGFIEPGEQCDCGMTPDRSGRSDCHRCCHPTTCMLRANATCGAGTCCDLQTCRPKSAGTVCRRSEKECDLPEYCTGQSEFCPDDVYKMDTIPCNHGQAYCVKGSCRSHTDQCRLLWGVTGESSHDKCYMSANVKGNKNGNCGYIRPAQRYVPCAYEDARCGLLQCRHLNEKLEFGMDSVAAVSAVFINNNGTIIPCRTAIIDLGLGDVDPGLVPDGAACGEHKMCLKQRCVSVESVRETIVNKHSSICPSNCSGHGVCNSEGHCHCEAGFAPPLCALPGPGGSVDSGPATDPTIQRNFMVAMYVIFLGIIPSVLLVMFLVYYSRHNVLYWWKKPRKSSPSPKKASLQHRISRSASKFAANFQNGPQNGAQPVVHTPSNPDDMSSSLLRSDSDRNPSGNINPSVNFFGNFKGFTLTPIEKSQDATDKSEVDAKTVKTAAESKSAKITPVHRSSSNSQSLMNQGVLKSTLRAAPPLPVVPAAAKTSPATSPAVKRTNSSVQNRIKALMTAEKPEETPVNPPSRPVISSPILEASTCTAKELISPLQGSKTLGPIRAAPTVPSASPDFPTRPLSMHSASSVLQKPLPEEPKRVKEGISLNRIASFLKQDKPKEKERNPVERSHSLPKNQNHQIKVALRNLQISKPIPQTEIELPVGAVSVVSDSEDEDSKAFVNRAQSMRAPQAQKPTIQSFGSMRQAPGVQRPVSIVGRPTAPPPPLPPQTEPNANQTNFPIENKSVDYVDCIEEKQAPLADINEESPDNIYAIIEESPESHSKPIPPPTSTIPQPNSGSSESMGLLGEIVNEIQNRNLESIYSVSTLKRKQKDRKEKEGSNRDSTYTNSEHYKTPESVYSNSGAKSTVSTTSSGYLLPSAVNVPNFVTKDTGEVTDSEKAPPSPTLKGGPNSKIPTFSRQVTPPGLKTFRNATPSPKSTLKNAHLSTKISNSPDLVSSCNVPETKNKTPDVINNNKIPNEAPKVATKPAVTAKPVDNRPPLKQGPNADKKLSAKTNQPLKPVNSSSNLNKTVEKNPPLNRANSKLENNVKSIADSLNKNKPKVVPKPTTLVNKTESTVKPNSTKLTAKPSNVASLQQKFENRKSIGKEINVRK

Uniprot

A0A2A4J1I9   A0A2A4JH11   A0A194RQ35   A0A0N0P9V9   A0A2A4J2X0   A0A2A4JG67   + More
A0A1W4WB38   D6X2H8   A0A1Y1NBX5   A0A2J7QKF8   A0A3L8E060   A0A1L8D955   A0A1L8D8V1   A0A1L8DTU0   A0A1L8DU35   A0A1B6KWF3   F4X4B8   A0A158NXT6   A0A195FHM2   A0A1B0CGA4   A0A348G5Z1   A0A1B6CW61   A0A0P6IW36   B0WZX2   A0A1Q3EZ65   A0A1Q3EZ67   A0A0K8WIJ1   A0A034VDR3   A0A026W9B0   A0A195E4G7   A0A1J1IE80   A0A336MLR0   A0A182WW07   A0A1A9VG20   Q7PSL4   A0A1S4GI55   E0VJV8   A0A182P8X1   A0A182HJZ4   A0A3F2Z0B2   A0A182FKZ8   A0A182K063   A0A151WQZ7   A0A182GZY6   A0A3F2YUQ7   W5J3W0   A0A2M4CHJ0   A0A182U0Q2   A0A182NL17   A0A2M4B9D7   A0A182QR87   A0A2M4B9A5   A0A1W4V5U3   A0A182IX59   B4LXB2  

Pubmed

26354079    18362917    19820115    28004739    30249741    21719571    + More
21347285    26999592    25348373    24508170    12364791    20566863    26483478    20966253    20920257    23761445    17994087   

EMBL

NWSH01003629    PCG66027.1    NWSH01001497    PCG71066.1    KQ459875    KPJ19602.1    + More
KQ459078    KPJ03818.1    PCG66028.1    PCG71067.1    KQ971372    EFA09442.2    GEZM01007661    JAV95018.1    NEVH01013262    PNF29075.1    QOIP01000002    RLU25775.1    GFDF01011207    JAV02877.1    GFDF01011206    JAV02878.1    GFDF01004300    JAV09784.1    GFDF01004299    JAV09785.1    GEBQ01024200    JAT15777.1    GL888633    EGI58714.1    ADTU01000484    ADTU01000485    ADTU01000486    ADTU01000487    ADTU01000488    ADTU01000489    ADTU01000490    ADTU01000491    ADTU01000492    ADTU01000493    KQ981606    KYN39504.1    AJWK01010900    AJWK01010901    AJWK01010902    FX985529    BBF97864.1    GEDC01019519    JAS17779.1    GDUN01000036    JAN95883.1    DS232219    EDS37797.1    GFDL01014453    JAV20592.1    GFDL01014448    JAV20597.1    GDHF01020588    GDHF01001445    JAI31726.1    JAI50869.1    GAKP01018731    GAKP01018730    JAC40222.1    KK107323    EZA52578.1    KQ979685    KYN19797.1    CVRI01000048    CRK98583.1    UFQT01001517    SSX30890.1    AAAB01008820    EAA05392.6    DS235231    EEB13664.1    APCN01002225    APCN01002226    APCN01002227    KQ982815    KYQ50233.1    JXUM01022077    KQ560620    KXJ81574.1    ADMH02002130    ETN58531.1    GGFL01000644    MBW64822.1    GGFJ01000479    MBW49620.1    AXCN02000090    GGFJ01000478    MBW49619.1    CH940650    EDW67790.2   

Proteomes

UP000218220    UP000053240    UP000053268    UP000192223    UP000007266    UP000235965    + More
UP000279307    UP000007755    UP000005205    UP000078541    UP000092461    UP000002320    UP000053097    UP000078492    UP000183832    UP000076407    UP000078200    UP000007062    UP000009046    UP000075885    UP000075840    UP000075903    UP000069272    UP000075881    UP000075809    UP000069940    UP000249989    UP000075882    UP000000673    UP000075902    UP000075884    UP000075886    UP000192221    UP000075880    UP000008792   

Pfam

PF01421   Reprolysin        + More
PF08516   ADAM_CR
PF00200   Disintegrin
PF01562   Pep_M12B_propep

Interpro

IPR024079   MetalloPept_cat_dom_sf        + More
IPR034027   Reprolysin_adamalysin       
IPR006586   ADAM_Cys-rich       
IPR002870   Peptidase_M12B_N       
IPR036436   Disintegrin_dom_sf       
IPR000742   EGF-like_dom       
IPR001590   Peptidase_M12B       
IPR013032   EGF-like_CS       
IPR001762   Disintegrin_dom       
IPR008979   Galactose-bd-like_sf       

SUPFAM

SSF57552   SSF57552       

Gene 3D

3.40.390.10     4.10.70.10     2.60.120.260    

CDD

cd04269  ZnMc_adamalysin_II_like

ProteinModelPortal

A0A2A4J1I9   A0A2A4JH11   A0A194RQ35   A0A0N0P9V9   A0A2A4J2X0   A0A2A4JG67   + More
A0A1W4WB38   D6X2H8   A0A1Y1NBX5   A0A2J7QKF8   A0A3L8E060   A0A1L8D955   A0A1L8D8V1   A0A1L8DTU0   A0A1L8DU35   A0A1B6KWF3   F4X4B8   A0A158NXT6   A0A195FHM2   A0A1B0CGA4   A0A348G5Z1   A0A1B6CW61   A0A0P6IW36   B0WZX2   A0A1Q3EZ65   A0A1Q3EZ67   A0A0K8WIJ1   A0A034VDR3   A0A026W9B0   A0A195E4G7   A0A1J1IE80   A0A336MLR0   A0A182WW07   A0A1A9VG20   Q7PSL4   A0A1S4GI55   E0VJV8   A0A182P8X1   A0A182HJZ4   A0A3F2Z0B2   A0A182FKZ8   A0A182K063   A0A151WQZ7   A0A182GZY6   A0A3F2YUQ7   W5J3W0   A0A2M4CHJ0   A0A182U0Q2   A0A182NL17   A0A2M4B9D7   A0A182QR87   A0A2M4B9A5   A0A1W4V5U3   A0A182IX59   B4LXB2  

PDB

3DSL     E-value=1.41825e-66,     Score=647

KEGG

101738149    no KO assigned | (RefSeq) disintegrin and metalloproteinase domain-containing protein 12

GO

GO:0016021   GO:0004222   GO:0007229   GO:0042802   GO:0006509   GO:0051259   GO:0005515   GO:0006508   GO:0008237   GO:0030126   GO:0030117   GO:0006418   GO:0003707   GO:0006281   GO:0006259  

Length:

1376

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

28.93651

Exp number, first 60 AAs:

0.00026

Total prob of N-in:

0.72597

inside

1  -  573

TMhelix

574  -  596

outside

597  -  1376

 

 

Pi

194.593604

Theta

149.392198

Tajima's D

1.005597

CLR

0.26226

CSRT

0.667216639168042

Interpretation

Uncertain