Gene

KWMTBOMO15584  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010725

Annotation

coatomer_protein_complex_subunit_alpha_[Bombyx_mori]

Location

Bomo_Chr26(-):3401434-3409134      View in EpiBrowser

Full name

Coatomer subunit alpha      

Location in the cell

Mitochondrial   Reliability : 1.706

CDS

ATGTTAAAAAAATTCGAGACGAAGTCTGCGCGGGTGAAAGGCATATCGTTTCATGCTAAGCGACCATGGGTGCTGGCTAGTTTGCACAATGGTGTGATTCAACTTTGGGATTATCGTATGTGTACATTACTTGAGAAATTTGATGAACATGATGGTCCAGTACGTGGAATTTGCTTCCATATTCAACAGCCTCTTTTCGTGTCGGGCGGAGATGACTACAAGATTAAGGTCTGGAACTACAAACAAAGAAGATGTCTATTCACATTGCTTGGTCACTTGGATTATATACGTACAACATTCTTCCATCATGAATACCCATGGATTTTAAGTGCATCTGATGATCAGACCATAAGAATTTGGAATTGGCAGTCTCGACAATGCATAAGTGTTCTCACCGGCCACAACCATTATGTAATGTGTGCTCAATTCCATCCCACTGAAGATCTTCTTGTTTCTGCTTCATTAGACCAGTCTGTAAGAGTCTGGGATTTCTCTGGACTGAGAAAAAAGAGTGTTGCTCCAGGACCTGCTGGACTGACTGAACACTTAAGGAATCCACAAGCAACAGATCTTTTTGGACAGGCTGATGCTGTTGTGAAGCACGTCTTGGAGGGCCACGATAGGGGTGTAAACTGGGCCTGTTTTCATCCTACTTTACCATTGATCGCATCTGCTGCAGATGACAGACAAGTGAAGCTTTGGAGAATGAATGATTCTAAGGCCTGGGAAGTGGATACATGTCGCGGCCACTACAACAATGTCTCCTGTGTTTTGTTTCACGCGAAACACGAACTCATCATATCTAACAGCGAGGATCTTTATATCAGAGTTTGGGACATGTCTAAAAGGACCCTCCTGCAGTCCTTTAGAAGGGAACACGAGAGGTACTGGGTGTTGACGTCCCACCCCACGCTGAACTTGTTCGCGGCGGGACACGACGGTGGGATGGTACTCTTCAAGCTGCAACGTGAGCGTCCAGCGTATGCAGTTCACAACAATATGCTGTTCTACATTAAAAACAGACACCTCCGTAAGTTAGACATGCTGACCAACCGGGACGCCCCAGTTATGCACTTGTCGAAGGGCGGTGGTCGCCAACAGCCTTACAGGTGA

Protein

MLKKFETKSARVKGISFHAKRPWVLASLHNGVIQLWDYRMCTLLEKFDEHDGPVRGICFHIQQPLFVSGGDDYKIKVWNYKQRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRIWNWQSRQCISVLTGHNHYVMCAQFHPTEDLLVSASLDQSVRVWDFSGLRKKSVAPGPAGLTEHLRNPQATDLFGQADAVVKHVLEGHDRGVNWACFHPTLPLIASAADDRQVKLWRMNDSKAWEVDTCRGHYNNVSCVLFHAKHELIISNSEDLYIRVWDMSKRTLLQSFRREHERYWVLTSHPTLNLFAAGHDGGMVLFKLQRERPAYAVHNNMLFYIKNRHLRKLDMLTNRDAPVMHLSKGGGRQQPYR

Description

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Subunit

Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.

Uniprot

D2Y4R2   A0A2H1VN08   A0A2A4JVN4   A0A3S2N867   A0A2A4JVE5   A0A194RP38   + More
A0A1E1WD57   S4PYF6   A0A0N1I3J3   A0A1B6F2D3   A0A1B6K337   A0A0C9PTC6   A0A0N0U519   A0A1W4XA38   A0A2J7RGJ5   A0A1B6L926   E9JAW6   A0A088ALI4   A0A0L7QRP2   E2A132   H9JMH2   A0A139WPQ7   F4WHH3   A0A195BVP9   K7JAS6   A0A158N931   A0A151J808   V5GMT3   A0A154P2K5   A0A2J7RGI4   A0A3L8DUY7   A0A1Y1LH14   A0A026W5T8   A0A0T6AXR4   E0VQA8   A0A1W7RAS0   A0A0L8I691   A0A1B6DMQ1   A0A1S3HB63   A0A0P4VMM2   T1HUE0   A0A2R7WBL9   A0A069DXW0   A0A1S3H8E8   A0A1S3H8Q1   T1J5P8   A0A2T7PRQ1   A0A0A9ZAE9   A0A224X5I0   A0A0K8T5U4   V4A0B8   A0A1L8DVB3   E9GA08   A0A1J1J2A7   A0A0P6HK97   A0A2H8TEQ2   A0A0P5G1R1   A0A0P6CZH5   A0A0P5ZVA3   A0A0P6F5Z0   A0A0P5TIB5   K1QET2   A0A087UGF1   A0A0P5U8E8   A0A0P5WR66   A7S9A4   A0A2S2PGV4   A0A3M6UD35   A0A2B4SR19   A0A2S2QZB4   T1ED49   J9K3N8   A0A336MCE9   A0A336LRA0   A0A1L8DVX3   A0A0P4ZCP9   Q16K68   A0A1S4FYI5   B0WVC7   A0A1Q3F8C9   A0A0P5V084   A0A0P4ZFS4   A0A182GDV0   A0A212EIT0   A0A023GDI1   A0A1E1XSX0   A0A224YQD2   A0A131YAP1   A0A023FTE7   A0A293MF99   A0A3S3PW73   A2I873   A0A131YJZ8   R7TX75   A0A131XLR0   A0A1E1X383   Q29DZ6   B4H455   U5EW24   A0A210Q2P5  

Pubmed

20967265    26354079    23622113    21282665    20798317    19121390    + More
18362917    19820115    21719571    20075255    21347285    30249741    28004739    24508170    20566863    27129103    26334808    25401762    26823975    23254933    21292972    22992520    17615350    30382153    17510324    26483478    22118469    29209593    28797301    17519023    26830274    28049606    28503490    15632085    17994087    28812685   

EMBL

GU322815    ADB66734.1    ODYU01003431    SOQ42188.1    NWSH01000595    PCG75452.1    + More
RSAL01000221    RVE44062.1    PCG75453.1    KQ459875    KPJ19608.1    GDQN01006187    JAT84867.1    GAIX01003373    JAA89187.1    KQ459078    KPJ03824.1    GECZ01025508    JAS44261.1    GECU01001827    JAT05880.1    GBYB01004627    GBYB01004628    GBYB01004629    JAG74394.1    JAG74395.1    JAG74396.1    KQ435794    KOX73744.1    NEVH01003779    PNF39948.1    GEBQ01019832    JAT20145.1    GL770679    EFZ10037.1    KQ414775    KOC61310.1    GL435643    EFN72866.1    BABH01016793    BABH01016794    KQ973148    KYB29922.1    GL888161    EGI66327.1    KQ976405    KYM91871.1    AAZX01002823    AAZX01004648    AAZX01008920    AAZX01008968    AAZX01009000    AAZX01014938    AAZX01017309    AAZX01019225    AAZX01019485    AAZX01024101    ADTU01009055    KQ979640    KYN20041.1    GALX01003057    JAB65409.1    KQ434807    KZC06156.1    PNF39949.1    QOIP01000004    RLU24227.1    GEZM01055821    JAV72924.1    KK107459    EZA50399.1    LJIG01022565    KRT79894.1    DS235408    EEB15564.1    GFAH01000155    JAV48234.1    KQ416454    KOF96909.1    GEDC01010376    JAS26922.1    GDKW01000789    JAI55806.1    ACPB03025161    KK854531    PTY16621.1    GBGD01000164    JAC88725.1    JH431866    PZQS01000002    PVD36070.1    GBHO01004829    GDHC01020868    JAG38775.1    JAP97760.1    GFTR01008671    JAW07755.1    GBRD01005030    JAG60791.1    KB202481    ESO90102.1    GFDF01003717    JAV10367.1    GL732536    EFX83790.1    CVRI01000064    CRL04977.1    GDIQ01026554    JAN68183.1    GFXV01000750    MBW12555.1    GDIQ01254576    JAJ97148.1    GDIQ01087478    JAN07259.1    GDIP01038539    JAM65176.1    GDIQ01053446    LRGB01001409    JAN41291.1    KZS12059.1    GDIP01125873    JAL77841.1    JH819194    EKC29564.1    KK119690    KFM76440.1    GDIP01116568    JAL87146.1    GDIP01082730    JAM20985.1    DS469602    EDO39748.1    GGMR01016015    MBY28634.1    RCHS01001746    RMX51607.1    LSMT01000034    PFX31523.1    GGMS01013883    MBY83086.1    AMQM01005779    KB097070    ESN99870.1    ABLF02019203    UFQS01000912    UFQT01000912    SSX07627.1    SSX27965.1    UFQS01000047    UFQT01000047    SSW98541.1    SSX18927.1    GFDF01003493    JAV10591.1    GDIP01214663    JAJ08739.1    CH477974    EAT34698.1    DS232122    EDS35527.1    GFDL01011243    JAV23802.1    GDIP01107481    JAL96233.1    GDIP01214662    JAJ08740.1    JXUM01056641    JXUM01056642    KQ561919    KXJ77156.1    AGBW02014588    OWR41378.1    GBBM01003511    JAC31907.1    GFAA01001373    JAU02062.1    GFPF01006823    MAA17969.1    GEFM01000188    JAP75608.1    GBBL01002591    JAC24729.1    GFWV01019649    MAA44377.1    NCKU01002601    NCKU01002592    RWS09241.1    RWS09262.1    EF173370    ABM68600.1    GEDV01010316    JAP78241.1    AMQN01011742    KB309073    ELT95580.1    GEFH01000562    JAP68019.1    GFAC01005448    JAT93740.1    CH379070    EAL30267.1    CH479208    EDW31170.1    GANO01000743    JAB59128.1    NEDP02005180    OWF43006.1   

Proteomes

UP000218220    UP000283053    UP000053240    UP000053268    UP000053105    UP000192223    + More
UP000235965    UP000005203    UP000053825    UP000000311    UP000005204    UP000007266    UP000007755    UP000078540    UP000002358    UP000005205    UP000078492    UP000076502    UP000279307    UP000053097    UP000009046    UP000053454    UP000085678    UP000015103    UP000245119    UP000030746    UP000000305    UP000183832    UP000076858    UP000005408    UP000054359    UP000001593    UP000275408    UP000225706    UP000015101    UP000007819    UP000008820    UP000002320    UP000069940    UP000249989    UP000007151    UP000285301    UP000014760    UP000001819    UP000008744    UP000242188   

PRIDE

D2Y4R2    H9JMH2   

Pfam

PF12894   ANAPC4_WD40        + More
PF04053   Coatomer_WDAD
PF00400   WD40
PF06957   COPI_C

Interpro

IPR015943   WD40/YVTN_repeat-like_dom_sf        + More
IPR001680   WD40_repeat       
IPR011048   Haem_d1_sf       
IPR024977   Apc4_WD40_dom       
IPR017986   WD40_repeat_dom       
IPR006692   Coatomer_WD-assoc_reg       
IPR020472   G-protein_beta_WD-40_rep       
IPR010714   Coatomer_asu_C       
IPR036322   WD40_repeat_dom_sf       
IPR016391   Coatomer_asu       
IPR019775   WD40_repeat_CS       
IPR011044   Quino_amine_DH_bsu       

SUPFAM

SSF50978   SSF50978        + More
SSF51004   SSF51004       
SSF50969   SSF50969       

Gene 3D

2.130.10.10    

ProteinModelPortal

D2Y4R2   A0A2H1VN08   A0A2A4JVN4   A0A3S2N867   A0A2A4JVE5   A0A194RP38   + More
A0A1E1WD57   S4PYF6   A0A0N1I3J3   A0A1B6F2D3   A0A1B6K337   A0A0C9PTC6   A0A0N0U519   A0A1W4XA38   A0A2J7RGJ5   A0A1B6L926   E9JAW6   A0A088ALI4   A0A0L7QRP2   E2A132   H9JMH2   A0A139WPQ7   F4WHH3   A0A195BVP9   K7JAS6   A0A158N931   A0A151J808   V5GMT3   A0A154P2K5   A0A2J7RGI4   A0A3L8DUY7   A0A1Y1LH14   A0A026W5T8   A0A0T6AXR4   E0VQA8   A0A1W7RAS0   A0A0L8I691   A0A1B6DMQ1   A0A1S3HB63   A0A0P4VMM2   T1HUE0   A0A2R7WBL9   A0A069DXW0   A0A1S3H8E8   A0A1S3H8Q1   T1J5P8   A0A2T7PRQ1   A0A0A9ZAE9   A0A224X5I0   A0A0K8T5U4   V4A0B8   A0A1L8DVB3   E9GA08   A0A1J1J2A7   A0A0P6HK97   A0A2H8TEQ2   A0A0P5G1R1   A0A0P6CZH5   A0A0P5ZVA3   A0A0P6F5Z0   A0A0P5TIB5   K1QET2   A0A087UGF1   A0A0P5U8E8   A0A0P5WR66   A7S9A4   A0A2S2PGV4   A0A3M6UD35   A0A2B4SR19   A0A2S2QZB4   T1ED49   J9K3N8   A0A336MCE9   A0A336LRA0   A0A1L8DVX3   A0A0P4ZCP9   Q16K68   A0A1S4FYI5   B0WVC7   A0A1Q3F8C9   A0A0P5V084   A0A0P4ZFS4   A0A182GDV0   A0A212EIT0   A0A023GDI1   A0A1E1XSX0   A0A224YQD2   A0A131YAP1   A0A023FTE7   A0A293MF99   A0A3S3PW73   A2I873   A0A131YJZ8   R7TX75   A0A131XLR0   A0A1E1X383   Q29DZ6   B4H455   U5EW24   A0A210Q2P5  

PDB

5NZV     E-value=0,     Score=1668

KEGG

100379186    K05236 coatomer subunit alpha | (RefSeq) COPA; coatomer protein complex subunit alpha

GO

GO:0005198   GO:0016192   GO:0030126   GO:0000139   GO:0006886   GO:0030117   GO:0006888   GO:0006891   GO:0006890   GO:0016740   GO:0010883   GO:1905345   GO:0005793   GO:0007112   GO:0000902   GO:0005515   GO:0006418   GO:0003707   GO:0006281   GO:0006259  

Subcellular location

Cytoplasm  
Golgi apparatus membrane  

Length:

370

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.11177

Exp number, first 60 AAs:

0.06376

Total prob of N-in:

0.02762

outside

1  -  370

 

 

Pi

287.369601

Theta

179.065797

Tajima's D

2.148558

CLR

0.148571

CSRT

0.907754612269387

Interpretation

Uncertain