Gene

KWMTBOMO15573

Annotation

PREDICTED:_ornithine_carbamoyltransferase-like_[Papilio_machaon]

Location

Bomo_Chr26(-):2989956-2994984      View in EpiBrowser

Full name

Ornithine carbamoyltransferase      

Location in the cell

Extracellular   Reliability : 2.057 PlasmaMembrane   Reliability : 1.557

CDS

ATGTCCGATGTAATTTTCGTGTCCACCACTACACACATGTGCGTTCAGAGGTTCGCTGAGAAATCCCTAGTTCCTGTCATCTGCATGAGATCAAGGACCCACGCAAGCATACAATCTTTGGCCACTATTATGGCTATAATTGAAGAATTTGGCAGTATGAGATGCGTCAACGTGTCATATATGGGACCACCCCATCCCATACTCAACTCCTACTTACTACTCTGTCCAATGTTGGGAGCAAACTTCAAGTTTAAATGTTGCTGTGAGAAATGTCCAGTGAGCCCGCTCCTTTACAAAAGCAGCGAAGAGTTGACAGCACAGTCGGCAACGGAAGTAAAGCAGTGCAGCGATAAAAACGATGTTTTGAAAAATACGTGCGTCGTCATCGCTGGTCCAACCACAAAGCATAGGGATAAAATTGAACTATTTAAATTTTCGATTGAAGATATACAAAGAAATACGTGCTGTAGCTGGTTGTTCTTCCACACGTGTCCTCGTGGCGAGGAGGTCGACGACAAGCTATTCTGTCATTTAAATTCTAGAACTTTCAACGCGATTGAGAACATGCATTACATTGCGGCCGCATTAATGGCTAATGCAGTAAAAGGCTACAAATTTTAA

Protein

MSDVIFVSTTTHMCVQRFAEKSLVPVICMRSRTHASIQSLATIMAIIEEFGSMRCVNVSYMGPPHPILNSYLLLCPMLGANFKFKCCCEKCPVSPLLYKSSEELTAQSATEVKQCSDKNDVLKNTCVVIAGPTTKHRDKIELFKFSIEDIQRNTCCSWLFFHTCPRGEEVDDKLFCHLNSRTFNAIENMHYIAAALMANAVKGYKF

Description

Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

Catalytic Activity

carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate

Similarity

Belongs to the ATCase/OTCase family.

Uniprot

A0A0N1IE63   A0A3S2P974   A0A0N1I562   A0A2H1WH98   A0A2A4JY73   A0A2H1WDI1   + More
A0A212ELB4   A0A2W1BIE1   A0A1B6LR21   A0A1B6GXT2   A0A1B6F9L0   E0VJX1   A0A2V3HW01   A0A1B6LSL4   W4HAE9   A0A3A5V5W9   A0A2E1HY82   A0A1Z9U4J3   A0A024U4Y8   A0A2E3FP09   A0A3Q3D5C2   A0A3Q1H8L7   G3NG75   A0A3Q1G590   C3Z6N9   A0A3A5W935   I6TG70   A0A2E6C3G1   A0A2D8MMX2   A0A3A5VI35   A0A2E9CA87   Q9IAV1   G0EHM9   A0A060YRP0   A0A3Q1I3E2   A0A3Q3BSJ4   B5XGX0   A0A1F2YGY7   A0A1W0A6M7   W5KB99   A0A2E3MBV3   A0A2E6C422   A0A3B4A7P3   A0A3A5ULC6   W5K357   A0A3B1IQV5   A0A3B4ZHK2   E9QHD9   A0A3M1UZJ5   A0A191XX94   A0A3Q1C7W9   A0A3P8SFK5   A0A2W1A7Y4   A0A191XXA9   A0A327HK61   A0A3B4DK13   A0A3B0RMP6   A0A1W4ZP30   A0A2E8V1J7   A0A2E6ATG9   A0A2D8MNZ6   A0A2D7JTN2   A0A1B6JQY6   A0A3A5VBG3   A0A147JVB8   A0A2I4BZ22   A0A075FVX6   C3ZW64   A0A1Y0I488   T0QEX0   A0A3A5UKU3   K4FTZ2   K3X374   A0A2E5T1S8   K4GB95   A0A1M6NG72   K4GC39   A0A2E6KY81   A0A2E9CD41   A0A2E9BE78   A0A317JCN4   A0A2E5IHH1   A0A1I7KWT2   A0A3R9FN05   A0A1G1G6W0   K4GB33   A0A2U3QGC0   A0A2S9EQZ8   N9DR21   A0A334ZI12   A0A334ZJ04   A0A3Q3KY79   A0A3F3MN50   A0A2D9NH14   A0A3Q3KY65   A0A371YNU8   A0A3F3GU39   A0A3Q3E3F7   G2JHY0   A0A372I4Z6  

EC Number

2.1.3.3

Pubmed

26354079    22118469    28756777    20566863    26573375    29337314    + More
18563158    21886865    24755649    20433749    27774985    25527045    25329095    25463417    23594743    27572167    24923324    23056606   

EMBL

LADJ01026996    KPJ21148.1    RSAL01000179    RVE44946.1    KQ459078    KPJ03804.1    + More
ODYU01008660    SOQ52438.1    NWSH01000363    PCG76965.1    ODYU01007610    SOQ50534.1    AGBW02014089    OWR42273.1    KZ150025    PZC74822.1    GEBQ01013938    JAT26039.1    GECZ01002539    JAS67230.1    GECZ01023196    JAS46573.1    DS235231    EEB13677.1    PSPH01000042    PXF23250.1    GEBQ01013285    JAT26692.1    KI913115    ETV88254.1    QQSA01000039    RJU87501.1    PAEE01000045    MAV03403.1    NHLY01000024    OUX48122.1    KI913963    ETW01305.1    PAOW01000019    MBA88175.1    GG666589    EEN51799.1    QQSK01000012    RJV00560.1    JQ753330    AFM85231.2    PBGM01000054    MBJ63066.1    NZOP01000026    MAM42267.1    QQSD01000041    RJU91727.1    PBXT01000037    MBS84140.1    AF134843    AAF61407.1    CP002838    AEM39382.1    FR912273    CDQ91775.1    BT050289    ACI70090.1    MELW01000076    OFW80066.1    JNBS01000405    OQS05905.1    PAQE01000006    MBB69635.1    PBGS01000005    MBJ63277.1    QQRW01000039    RJU80775.1    BX571713    RFHV01000498    RMG33908.1    KU229875    ANJ45170.1    QGNP01000014    PZC40206.1    KU229897    ANJ45192.1    PAMN02000038    RAH14658.1    UOEA01000074    VAV84835.1    PBWC01000022    MBR95472.1    PBGJ01000021    MBJ47288.1    NZOP01000045    MAM42642.1    NZFV01000024    MAJ01310.1    GECU01006129    JAT01578.1    QQSC01000028    RJU89434.1    LQMQ01000041    KUO40457.1    KF900463    AIE95855.1    GG666696    EEN43195.1    CP021425    ARU55292.1    JH767160    EQC33291.1    QQRY01000059    RJU80585.1    JX053082    AFK11310.1    GL376611    PBEG01000027    MBI52252.1    JX212215    AFM90529.1    FRAF01000006    SHJ94697.1    JX211927    AFM90241.1    PBJJ01000011    MBK71441.1    PBWW01000014    MBS85152.1    PBXF01000023    MBS73274.1    PSRN01000290    PWU13224.1    PBBZ01000031    MBH35034.1    FPBV01000020    SFV01895.1    RHXF01000003    RSE38023.1    MHEF01000060    OGW39708.1    JX212170    AFM90484.1    OUUY01000068    SPQ00405.1    PCQO01000001    PRC18060.1    APQD01000012    ENV82943.1    UFLS01001392    SSS46990.1    UFLS01001391    SSS46988.1    QKWF01000092    PZM17407.1    NZTR01000008    MAP58736.1    PYIX02000021    RFC83112.1    APQE01000003    ENV87869.1    QVQG01000017    RFU09927.1   

Proteomes

UP000053240    UP000283053    UP000053268    UP000218220    UP000007151    UP000009046    + More
UP000019040    UP000276217    UP000024375    UP000264820    UP000257200    UP000007635    UP000001554    UP000267582    UP000281630    UP000001037    UP000193380    UP000265040    UP000264800    UP000087266    UP000243217    UP000018467    UP000261520    UP000271368    UP000261400    UP000000437    UP000257160    UP000265080    UP000261440    UP000192224    UP000282502    UP000074294    UP000192220    UP000196027    UP000030762    UP000268248    UP000184016    UP000228988    UP000183508    UP000281148    UP000245125    UP000238456    UP000018460    UP000263608    UP000261660    UP000248662    UP000240957    UP000018427    UP000263964   

Pfam

PF00185   OTCace        + More
PF00083   Sugar_tr
PF02729   OTCace_N

Interpro

IPR005828   MFS_sugar_transport-like        + More
IPR006131   Asp_carbamoyltransf_Asp/Orn-bd       
IPR020846   MFS_dom       
IPR036901   Asp/Orn_carbamoylTrfase_sf       
IPR036259   MFS_trans_sf       
IPR006132   Asp/Orn_carbamoyltranf_P-bd       
IPR006130   Asp/Orn_carbamoylTrfase       
IPR002292   Orn/put_carbamltrans       
IPR024904   OTCase_ArgI       

SUPFAM

SSF103473   SSF103473        + More
SSF53671   SSF53671       

Gene 3D

3.40.50.1370    

CDD

cd06174  MFS

ProteinModelPortal

A0A0N1IE63   A0A3S2P974   A0A0N1I562   A0A2H1WH98   A0A2A4JY73   A0A2H1WDI1   + More
A0A212ELB4   A0A2W1BIE1   A0A1B6LR21   A0A1B6GXT2   A0A1B6F9L0   E0VJX1   A0A2V3HW01   A0A1B6LSL4   W4HAE9   A0A3A5V5W9   A0A2E1HY82   A0A1Z9U4J3   A0A024U4Y8   A0A2E3FP09   A0A3Q3D5C2   A0A3Q1H8L7   G3NG75   A0A3Q1G590   C3Z6N9   A0A3A5W935   I6TG70   A0A2E6C3G1   A0A2D8MMX2   A0A3A5VI35   A0A2E9CA87   Q9IAV1   G0EHM9   A0A060YRP0   A0A3Q1I3E2   A0A3Q3BSJ4   B5XGX0   A0A1F2YGY7   A0A1W0A6M7   W5KB99   A0A2E3MBV3   A0A2E6C422   A0A3B4A7P3   A0A3A5ULC6   W5K357   A0A3B1IQV5   A0A3B4ZHK2   E9QHD9   A0A3M1UZJ5   A0A191XX94   A0A3Q1C7W9   A0A3P8SFK5   A0A2W1A7Y4   A0A191XXA9   A0A327HK61   A0A3B4DK13   A0A3B0RMP6   A0A1W4ZP30   A0A2E8V1J7   A0A2E6ATG9   A0A2D8MNZ6   A0A2D7JTN2   A0A1B6JQY6   A0A3A5VBG3   A0A147JVB8   A0A2I4BZ22   A0A075FVX6   C3ZW64   A0A1Y0I488   T0QEX0   A0A3A5UKU3   K4FTZ2   K3X374   A0A2E5T1S8   K4GB95   A0A1M6NG72   K4GC39   A0A2E6KY81   A0A2E9CD41   A0A2E9BE78   A0A317JCN4   A0A2E5IHH1   A0A1I7KWT2   A0A3R9FN05   A0A1G1G6W0   K4GB33   A0A2U3QGC0   A0A2S9EQZ8   N9DR21   A0A334ZI12   A0A334ZJ04   A0A3Q3KY79   A0A3F3MN50   A0A2D9NH14   A0A3Q3KY65   A0A371YNU8   A0A3F3GU39   A0A3Q3E3F7   G2JHY0   A0A372I4Z6  

PDB

1VLV     E-value=4.99289e-09,     Score=142

KEGG

101738188    K00611 ornithine carbamoyltransferase [EC:2.1.3.3] | (RefSeq) uncharacterized LOC101738188

PATHWAY

00220    Arginine biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0016597   GO:0006520   GO:0022857   GO:0016743   GO:0016021   GO:0004585   GO:0016740   GO:0019240   GO:0005739   GO:0042450   GO:0005737   GO:0032549   GO:0007165   GO:0006418   GO:0003707   GO:0006281   GO:0006259  

Subcellular location

Cytoplasm  

Length:

206

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.356

Exp number, first 60 AAs:

0.05793

Total prob of N-in:

0.08468

outside

1  -  206

 

 

Pi

23.340275

Theta

27.756884

Tajima's D

-0.827377

CLR

27.381181

CSRT

0.173591320433978

Interpretation

Uncertain