Gene

KWMTBOMO15543  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010804

Annotation

PREDICTED:_DNA-directed_RNA_polymerase_I_subunit_RPA2_[Papilio_polytes]

Location

Bomo_Chr26(+):2247710-2262417      View in EpiBrowser

Full name

DNA-directed RNA polymerase subunit beta      

Location in the cell

Cytoplasmic   Reliability : 1.177 Mitochondrial   Reliability : 1.416

CDS

ATGAATCCAAAAAAACTAGCCCAAAACCCATCATTGGCGTACACAAGCCACCCAGATTATAGAAAACCGCCAAAAATAGCAAATCCGTACCTTCAAAGTCTTGGAGCGCCTCACATAGATTCATTCAATTATATGCTGGACGATGGCCTGAAATTTGCTATAGCTGATCTATTGCCATCGGAATTTGAGTTACCTAGTGGTGAAAAGGTCAAAGTGACAATCGATGAAGCAGCATTCGCTAAACCCAATGTTCCCATGGATACAGTAGGGGTTAAATCTCAAGTGGTCCTCCCAACAGAATGCCGGCAGAGAGCTGCTACATACAAGGGAGAGTTAAAGATCAGAGTCACTCTGTGCATTGACGGAAGGTCTGTCACCATTGAGAGGTCCTTAGGTTATTTACCCATTATGATTAAGTCTAAAATGTGTCATTTGGCTGATTTATCACCTGAAGAACTGATTGAGAAAAATGAACATGCTGATGAATGGGGTGGATATTTTGTAATAAAGGGCCATGAGCGTCTAGCCCGTATGTTGTTGGTTACACGAAGGAACTACCCTGTGGCCATCAAGCGGTCAGGATGGAAGATGCGAGGAAATCTCTTCTCAGACTATGGAGTATTAGTACGTTGCGTCACCTCCGATCAGACCAGCACGAACAATGTTCTGCATTTCCTAACGAATGGCACGTGCAAGCTGATGTTCTCGTACCGCAAGATGATGTACTACGCTCCCCTACTCCTCATAATGAAGTGCCTGGTCCCGTGGCCGGATCACTACATATACACACTGCTGTTGCAGCATAATAAGAATGATTTGTACTACGTCAATTGCATCCAGAATATGCTCCGAGAGCTCCACGAGGAAGGTCTGCACACATCCGAAGAGTGTCGCCTGTACTTAGGCAAGATGTTCCGCTCCAAGCTGTACGAGCTGCCGCCCTGGGCTACCGAGATGGAGGCGGCCCAGTTCCTCCTGGACCGATGCGTTATGATCCACCTAAAGAACAACACGGACAAGTTCCACGCTTTAGTCTTCATGGTCCAGAAGCTCTACGATCTGGTTCAGAATAAGTGTAAGGTGGAAGGAGCGGATGCTGTAATGATGCAGGAGGTGATGGTGGGAGGCCACCTCTACTTGCAGGTGTTGAAGGAAAGACTCCAGAATATTCTCAATAACGTCAGGATACAGATCCTTAAACGCGCCAAGACAACACATCGACTAGTCATCGGTCATAAAGAGCTTCAACAAATCCTCCGCGCGTGCGGGAGTCTAGAGCAGAAGATGGAGACGTTCTTGGCCACGGGGAATGCGCCCTCCAGCAACGTCAACCTCACGCAGTACAAGGGACTCACCATCGTGGCCGAGAACATCAACAGGATGCGATATATGTCGCATTTCAAGTCGATTCACCGCGGCTCGTTCTTCATGGAGATGCGCACGACGGAGGCCCGGCAGCTGCTGCCGGACGCGTGGGGCTTCGTGTGTCCCGTGCACACGCCCGACGGCGCGCCCTGCGGACTGCTCAACCACCTCACCATGTCCGCGCAGATCACACAAATTCCCGATCAAAAATTAGTGGATAATCTTCCTTTAGTTTTACAAAACTGCGGTATGGAGCCCATAAGCAGCGTGCTCTGCGACCGCGACACGTACAAGTACCCGGTGTTCGTGGACGGGCGGCTGGTGGGCTACATCGCGGAGAGCGGCGCCGAGAAGTCGGCCGCCTACCTCCGCACCCTCAAGATAAAGGGCGAAGAGGTTCCGATCACTACCGAGATTGTGGTCATCCCTAAAAAACAGATCTGCGCCCAATACCCTGGCATATTCCTGATGACGACGGAGGCCCGCATGATGCGGCCGGTCATCAACCTGGCCACCTCGCAGTTAGAGCTGATCGGTACAATGGAGCAGCTGTACCTGGATATCGCCATAACGCCGAACGAGGTTCACAAAGGTCAGACGACGCACATGGAGCTTTCGCAGTCAGCGTTCCTGAGCAACTTGGCGCAGCTGGTGCCGATGCCGGACTGTAATCAGTCTCCAAGGAACATGTACCAGTGCCAGATGGGCAAGCAGACGATGGGCACCCCGGTGCACACGTGGGGCGGCACCGGCCCCGGCAAGCTGTACCGGCTGCAGACTCCCGCCGCGCCGCTGTTCCGCCCCGCGCACCACGACCGCCTCGCCCTCGACGACTACCCCGCCGGGACCAACGCCATCGTCGCCGTCATATCCTACACGGTCAGTACCCCTAACCTGACCTTGAACCCTTAG

Protein

MNPKKLAQNPSLAYTSHPDYRKPPKIANPYLQSLGAPHIDSFNYMLDDGLKFAIADLLPSEFELPSGEKVKVTIDEAAFAKPNVPMDTVGVKSQVVLPTECRQRAATYKGELKIRVTLCIDGRSVTIERSLGYLPIMIKSKMCHLADLSPEELIEKNEHADEWGGYFVIKGHERLARMLLVTRRNYPVAIKRSGWKMRGNLFSDYGVLVRCVTSDQTSTNNVLHFLTNGTCKLMFSYRKMMYYAPLLLIMKCLVPWPDHYIYTLLLQHNKNDLYYVNCIQNMLRELHEEGLHTSEECRLYLGKMFRSKLYELPPWATEMEAAQFLLDRCVMIHLKNNTDKFHALVFMVQKLYDLVQNKCKVEGADAVMMQEVMVGGHLYLQVLKERLQNILNNVRIQILKRAKTTHRLVIGHKELQQILRACGSLEQKMETFLATGNAPSSNVNLTQYKGLTIVAENINRMRYMSHFKSIHRGSFFMEMRTTEARQLLPDAWGFVCPVHTPDGAPCGLLNHLTMSAQITQIPDQKLVDNLPLVLQNCGMEPISSVLCDRDTYKYPVFVDGRLVGYIAESGAEKSAAYLRTLKIKGEEVPITTEIVVIPKKQICAQYPGIFLMTTEARMMRPVINLATSQLELIGTMEQLYLDIAITPNEVHKGQTTHMELSQSAFLSNLAQLVPMPDCNQSPRNMYQCQMGKQTMGTPVHTWGGTGPGKLYRLQTPAAPLFRPAHHDRLALDDYPAGTNAIVAVISYTVSTPNLTLNP

Description

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic Activity

a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)

Similarity

Belongs to the RNA polymerase beta chain family.

Uniprot

H9JMQ1   A0A0N1ICC8   A0A212FAC3   A0A3S2NX40   A0A2W1BZB1   A0A212F425   + More
A0A1W4XHB8   A0A154NVW8   A0A088A2A1   A0A232EXH0   A0A2A3EBT9   A0A1Y1KKJ0   K7IWJ3   N6TC52   E2B687   A0A0J7NJI8   A0A1B6M535   F4WB73   A0A1B6G6E8   A0A023F422   A0A2J7Q9B5   E9IAZ0   A0A158P3I7   A0A1B6K312   A0A1B6CSM5   A0A151JXF7   A0A1B6CFG7   A0A0P4VRX0   U4U813   A0A0V0G7L3   A0A151J8Q7   A0A151HZI2   A0A026WUS5   A0A224XGY9   A0A151IL56   J9E9J9   A0A182GW05   A0A182GJ47   A0A224XFY6   A0A0L0CDA1   A0A1I8QCQ3   D6WVZ3   E0V8Y6   A0A151XDM1   A0A1Q3EXN9   A0A1I8M669   A0A067QQ90   A0A0P5QZ94   A0A0N8E7P0   A0A0P5L5Y1   A0A0P6GD02   J9K6G2   W8B904   A0A146LR30   A0A146LJQ4   A0A0A9VR72   B0W5T2   A0A1J1HL88   A0A0P6IJK5   A0A0P4ZUJ3   A0A2H8TU91   A0A0A1XSL8   A0A0K8UKU8   A0A034WES4   A0A1A9V0X0   A0A1B0FD37   A0A1A9YSF8   A0A1A9ZQR0   A0A2S2QW78   A0A1A9WUR2   A0A2M4CVF7   A0A2M4BD15   A0A2M4CU57   A0A2M4BDL2   A0A2M4BCX8   W5J6H6   A0A2M4AHX0   A0A2M4AIY3   A0A0L7R3C5   A0A182L5Q9   Q7QG74   A0A182F4E3   A0A3Q0ITX4   A0A182X7Q7   A0A182IE12   A0A182NE81   A0A182RGH5   E9HT05   A0A182VG37   A0A084VPA9   A0A182TZ99   A0A182MM49   A0A0K2TFZ6   A0A182P955   B4KFJ3   B3MUI2   B4N0U3   A0A182Q1G0   A0A182JYE9   A0A182VV21  

EC Number

2.7.7.6

Pubmed

19121390    26354079    22118469    28756777    28648823    28004739    + More
20075255    23537049    20798317    21719571    25474469    21282665    21347285    27129103    24508170    30249741    17510324    26483478    26108605    18362917    19820115    20566863    25315136    24845553    24495485    26823975    25401762    25830018    25348373    20920257    23761445    20966253    12364791    21292972    24438588    17994087   

EMBL

BABH01016707    BABH01016708    BABH01016709    BABH01016710    KQ459910    KPJ19329.1    + More
AGBW02009499    OWR50682.1    RSAL01000118    RVE46764.1    KZ149936    PZC77143.1    AGBW02010450    OWR48487.1    KQ434769    KZC03787.1    NNAY01001730    OXU23104.1    KZ288311    PBC28511.1    GEZM01085172    GEZM01085171    GEZM01085170    JAV60155.1    APGK01035628    APGK01035629    APGK01035630    KB740928    ENN77884.1    GL445930    EFN88780.1    LBMM01004251    KMQ92660.1    GEBQ01008946    JAT31031.1    GL888058    EGI68546.1    GECZ01011759    JAS58010.1    GBBI01002988    JAC15724.1    NEVH01016943    PNF25173.1    GL762091    EFZ22265.1    ADTU01008085    ADTU01008086    ADTU01008087    ADTU01008088    GECU01001857    JAT05850.1    GEDC01021045    JAS16253.1    KQ981604    KYN39719.1    GEDC01025130    JAS12168.1    GDKW01000777    JAI55818.1    KB632064    ERL88468.1    GECL01002690    JAP03434.1    KQ979488    KYN21228.1    KQ976710    KYM77038.1    KK107088    QOIP01000008    EZA59800.1    RLU19525.1    GFTR01008584    JAW07842.1    KQ977133    KYN05487.1    CH477305    EJY57536.1    JXUM01092462    KQ563989    KXJ72968.1    JXUM01067297    KQ562443    KXJ75905.1    GFTR01008924    JAW07502.1    JRES01000561    KNC30197.1    KQ971359    EFA08638.2    DS234986    EEB09842.1    KQ982268    KYQ58474.1    GFDL01014970    JAV20075.1    KK853598    KDR06420.1    GDIQ01108127    JAL43599.1    GDIQ01053748    JAN40989.1    GDIQ01174495    JAK77230.1    GDIQ01034999    JAN59738.1    ABLF02026514    GAMC01011438    JAB95117.1    GDHC01009044    JAQ09585.1    GDHC01011513    JAQ07116.1    GBHO01044682    JAF98921.1    DS231844    EDS35735.1    CVRI01000010    CRK88797.1    GDIQ01010006    JAN84731.1    GDIP01221463    JAJ01939.1    GFXV01006019    MBW17824.1    GBXI01000276    JAD14016.1    GDHF01025007    JAI27307.1    GAKP01006140    JAC52812.1    CCAG010003896    GGMS01012803    MBY82006.1    GGFL01004640    MBW68818.1    GGFJ01001756    MBW50897.1    GGFL01004641    MBW68819.1    GGFJ01001757    MBW50898.1    GGFJ01001758    MBW50899.1    ADMH02002133    ETN58440.1    GGFK01007065    MBW40386.1    GGFK01007247    MBW40568.1    KQ414663    KOC65372.1    AAAB01008839    EAA05843.4    APCN01004553    GL732762    EFX65117.1    ATLV01014994    KE524999    KFB39803.1    AXCM01000251    HACA01007592    CDW24953.1    CH933807    EDW13108.2    CH902624    EDV33511.1    CH963920    EDW77706.1    AXCN02000868   

Proteomes

UP000005204    UP000053240    UP000007151    UP000283053    UP000192223    UP000076502    + More
UP000005203    UP000215335    UP000242457    UP000002358    UP000019118    UP000008237    UP000036403    UP000007755    UP000235965    UP000005205    UP000078541    UP000030742    UP000078492    UP000078540    UP000053097    UP000279307    UP000078542    UP000008820    UP000069940    UP000249989    UP000037069    UP000095300    UP000007266    UP000009046    UP000075809    UP000095301    UP000027135    UP000007819    UP000002320    UP000183832    UP000078200    UP000092444    UP000092443    UP000092445    UP000091820    UP000000673    UP000053825    UP000075882    UP000007062    UP000069272    UP000079169    UP000076407    UP000075840    UP000075884    UP000075900    UP000000305    UP000075903    UP000030765    UP000075902    UP000075883    UP000075885    UP000009192    UP000007801    UP000007798    UP000075886    UP000075881    UP000075920   

PRIDE

H9JMQ1   

Pfam

PF04565   RNA_pol_Rpb2_3        + More
PF00562   RNA_pol_Rpb2_6
PF06883   RNA_pol_Rpa2_4
PF04561   RNA_pol_Rpb2_2
PF04563   RNA_pol_Rpb2_1
PF04560   RNA_pol_Rpb2_7
PF12309   KBP_C

Interpro

IPR007644   RNA_pol_bsu_protrusion        + More
IPR037034   RNA_pol_Rpb2_2_sf       
IPR014724   RNA_pol_RPB2_OB-fold       
IPR037033   DNA-dir_RNAP_su2_hyb_sf       
IPR007645   RNA_pol_Rpb2_3       
IPR015712   DNA-dir_RNA_pol_su2       
IPR007121   RNA_pol_bsu_CS       
IPR009674   Rpa2_dom_4       
IPR007642   RNA_pol_Rpb2_2       
IPR007120   DNA-dir_RNAP_su2_dom       
IPR007641   RNA_pol_Rpb2_7       
IPR022083   KBP       

Gene 3D

2.40.270.10     2.40.50.150     3.90.1110.10    

CDD

cd00653  RNA_pol_B_RPB2

ProteinModelPortal

H9JMQ1   A0A0N1ICC8   A0A212FAC3   A0A3S2NX40   A0A2W1BZB1   A0A212F425   + More
A0A1W4XHB8   A0A154NVW8   A0A088A2A1   A0A232EXH0   A0A2A3EBT9   A0A1Y1KKJ0   K7IWJ3   N6TC52   E2B687   A0A0J7NJI8   A0A1B6M535   F4WB73   A0A1B6G6E8   A0A023F422   A0A2J7Q9B5   E9IAZ0   A0A158P3I7   A0A1B6K312   A0A1B6CSM5   A0A151JXF7   A0A1B6CFG7   A0A0P4VRX0   U4U813   A0A0V0G7L3   A0A151J8Q7   A0A151HZI2   A0A026WUS5   A0A224XGY9   A0A151IL56   J9E9J9   A0A182GW05   A0A182GJ47   A0A224XFY6   A0A0L0CDA1   A0A1I8QCQ3   D6WVZ3   E0V8Y6   A0A151XDM1   A0A1Q3EXN9   A0A1I8M669   A0A067QQ90   A0A0P5QZ94   A0A0N8E7P0   A0A0P5L5Y1   A0A0P6GD02   J9K6G2   W8B904   A0A146LR30   A0A146LJQ4   A0A0A9VR72   B0W5T2   A0A1J1HL88   A0A0P6IJK5   A0A0P4ZUJ3   A0A2H8TU91   A0A0A1XSL8   A0A0K8UKU8   A0A034WES4   A0A1A9V0X0   A0A1B0FD37   A0A1A9YSF8   A0A1A9ZQR0   A0A2S2QW78   A0A1A9WUR2   A0A2M4CVF7   A0A2M4BD15   A0A2M4CU57   A0A2M4BDL2   A0A2M4BCX8   W5J6H6   A0A2M4AHX0   A0A2M4AIY3   A0A0L7R3C5   A0A182L5Q9   Q7QG74   A0A182F4E3   A0A3Q0ITX4   A0A182X7Q7   A0A182IE12   A0A182NE81   A0A182RGH5   E9HT05   A0A182VG37   A0A084VPA9   A0A182TZ99   A0A182MM49   A0A0K2TFZ6   A0A182P955   B4KFJ3   B3MUI2   B4N0U3   A0A182Q1G0   A0A182JYE9   A0A182VV21  

PDB

6HLS     E-value=6.068e-151,     Score=1373

KEGG

101736995    K03002 DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6] | (RefSeq) DNA-directed RNA polymeras

GO

GO:0032549   GO:0006351   GO:0005634   GO:0003899   GO:0003677   GO:0016021   GO:0005736   GO:0006360   GO:0045793   GO:0022857   GO:0007165   GO:0006418   GO:0003707   GO:0006281   GO:0006259  

PANTHER

PTHR20856  

Length:

758

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.45956

Exp number, first 60 AAs:

0.00021

Total prob of N-in:

0.06361

outside

1  -  758

 

 

Pi

230.40007

Theta

176.378838

Tajima's D

0.927695

CLR

0.236243

CSRT

0.638518074096295

Interpretation

Uncertain