Gene

KWMTBOMO15502  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010791

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_glutamyl-tRNA(Gln)_amidotransferase_subunit_A?_mitochondrial_[Bombyx_mori]

Location

Bomo_Chr26(+):875166-879190      View in EpiBrowser

Full name

Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial      

Alternative Name

Glutaminyl-tRNA synthase-like protein 1

Location in the cell

Nuclear   Reliability : 2.789

CDS

ATGAATAAATTGTCATCTTACACGATAAAAGAGATACACAGGGCGTATCGTGATAAAATACTAACGCCGACAAGTTTTGTTGATTTGTGTCTACAAAAGGCCATACAGAGTATCGAATTGAATGCCTTTACCACTATAACTGACGACGAAGCAGAAAGTCACGCAATCGAAAGCGAAAAACGACTTTACGTCGACAGAAAACCGAAGACTCTGGACGGTATTACCATCGGAATAAAAGACAATTTCTGTACTAGTAATATACCGACGACATGCGGCTCAGAAATGCTAAAAAACTTCGTTCCTACATACAACGCTACGGTATACGCAAGATTGAGGAAAGCCGGCGCTTGTTTGGTAGGAAAATGTAATTTAGACGAATTTGCAATGGGCTCCGGTACCATCGATTCCATATTCGGTCCAACCCGGAACCCATGGCAGTACGAAAGAAATAACTGGAAAATAGCTGGTGGCAGCTCTGGTGGAAGCGCTGTTGCCGTGACCACCGGATCATGCGTAGCTGCAATAGGCTCTGACACTGGTGGTTCAACTAGAAATCCAGCAGCTTTATGTGGTGTTGTTGGGTTAAAACCCTCATATGGCCTGGTGTCACGTTATGGCCTAATACCTTTAGTAAATTCAATGGATGTACCAGGAATACTGACAAGAGATATTGATGATTGTGTTGCCGTATTGAATTCAGTGGCAGGTCCTGATGACTTAGACTCTACGACTATCAAACGAGATTATAAACCAATAGAAATTCAAGATATTGATATGTCATCCGTAAAGATTGGTATACCAAAAGAATATCATTGTGAGGGGATGGATAGGGAAGTAATAGACACATGGAGTTATGTTAGTGATATTCTTGAAAAAGAAAACTGTATTGTAAAACAAGTCTCTTTGCCATATTCCTCAGCTTCAATAGTAGTATATTCTATACTGAATCAATGTGAAGTCGCAAGCAACATGGCTAGATATGATGGTATTGAATATGGTCTTAGAACTGATGAGACATATTCCACAGAAGAATTGTATGCGTCATCGAGGCTACGAGGATTCAGTGAGGTGGTAAGATCTAGGATTTTAACAGGGAACTATTTTCTACTGACGAGAAACTACAACAAATATTTTATTAAAGCTTTGAAACTACGAAGGCTTATATCAGATGATTTTAATAAAGTTTTTAATGGGGAGGATAAAGTTGATCTTCTATTGACACCAACCACATTATCTGACGCGCCGTCTTATGAAGATTTCTCATTGAAGAATAATCGTGATCAATGTGCTTTTCAAGATTTTTGCACACAACCAGCAAACATGGCCGGAATACCAGCAGTTTCAATACCGATCAGACTATCTAAAAATGGTCTTCCGTTATCCCTGCAGCTCATGGGGCCGATGTTTTCTGAAGAACTGATGTTAAATGTAGCGAAGAAGATTGAAACTAACCTTGCATCAGAAACCCTAGCGAAGCTCAACATACGCATTGACACATTACCCCAAAAATACCAACAGCTACTCGACAAACTGGCAGCAAGCCAATCATCACTTGGTATAAACCAATTAGATCACGTCTCCATATCCTTAGAGCAAACGAAAGACATTACAGAGAATCTAGAAGATGACTATGAGATTCTGAAACTTAAACACAAAGATCTAGAATTACAGAGACGGATCGAGAAGAACATAAAGTTTATCGATGAACTGAGAAGGGAATTGGAAATGTCCAGGGAGTCATTGTCTAATCAAAACCCTGGGCCAGATAATGTCCAGGATTACATAAGACAACTCAAGCAAAAGGTAGTTTCTTATGAAGAAAGCTGTACTAAAGCAAAGGTTAAATACAATAAGCTGAGCATTCCCGATACTATACTTCCCAAGTCTTTATCAGTTCTGGTGACGTCACACGAAGCCCTCCTCGAGGAGGCGAGGTCTCTCCGTCAGCGCGCCGAAGACATAACCTTCGCGAGAGACGCCATACAGAACTTGCATAGACTGAGAAGATAA

Protein

MNKLSSYTIKEIHRAYRDKILTPTSFVDLCLQKAIQSIELNAFTTITDDEAESHAIESEKRLYVDRKPKTLDGITIGIKDNFCTSNIPTTCGSEMLKNFVPTYNATVYARLRKAGACLVGKCNLDEFAMGSGTIDSIFGPTRNPWQYERNNWKIAGGSSGGSAVAVTTGSCVAAIGSDTGGSTRNPAALCGVVGLKPSYGLVSRYGLIPLVNSMDVPGILTRDIDDCVAVLNSVAGPDDLDSTTIKRDYKPIEIQDIDMSSVKIGIPKEYHCEGMDREVIDTWSYVSDILEKENCIVKQVSLPYSSASIVVYSILNQCEVASNMARYDGIEYGLRTDETYSTEELYASSRLRGFSEVVRSRILTGNYFLLTRNYNKYFIKALKLRRLISDDFNKVFNGEDKVDLLLTPTTLSDAPSYEDFSLKNNRDQCAFQDFCTQPANMAGIPAVSIPIRLSKNGLPLSLQLMGPMFSEELMLNVAKKIETNLASETLAKLNIRIDTLPQKYQQLLDKLAASQSSLGINQLDHVSISLEQTKDITENLEDDYEILKLKHKDLELQRRIEKNIKFIDELRRELEMSRESLSNQNPGPDNVQDYIRQLKQKVVSYEESCTKAKVKYNKLSIPDTILPKSLSVLVTSHEALLEEARSLRQRAEDITFARDAIQNLHRLRR

Description

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).

Catalytic Activity

ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate

Subunit

Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.
Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

Similarity

Belongs to the amidase family. GatA subfamily.

Keywords

ATP-binding   Complete proteome   Ligase   Mitochondrion   Nucleotide-binding   Protein biosynthesis   Reference proteome  

Feature

chain  Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

Uniprot

H9JMN8   A0A2H1VJ00   A0A212EV54   A0A0L7LNI1   A0A0N1PF89   A0A194PLQ4   + More
A0A2A4JTP0   A0A2W1BZT4   A0A3S2N5M0   A0A3B0KBW5   B3LVB4   B4MBW2   Q29BT3   B4K5Z0   B4GPP0   A0A1W4UPQ1   A0A0L0CB66   B0WAE3   B4ILV6   B4NHY9   B3P381   W8C564   B4QTW1   A0A0M3QY70   B4JYK4   H5V8A8   B4PMQ7   Q9VE09   A0A1I8MZ60   A0A1Q3F751   A0A1I8PPZ0   Q17H91   A0A2K7P689   A0A1J1IEV0   A0A182GXB9   A0A0K8UXK0   A0A182JN09   A0A182RBK1   A0A182VBM5   A0A182XFF8   A0A182FXF8   Q7QH64   A0A182I843   W5J8A2   A0A182L7R2   A0A182YF37   A0A182VX24   A0A084VTD7   A0A182T1L4   A0A182NKS4   A0A182P455   A0A182QRT8   A0A182JVJ5   D6WJE7   A0A232F8D4   K7J1T3   A0A1Y1L0R6   A0A1B0CF56   N6TK20   A0A131Z5V6   A0A224YRR3   L7M5A1   A0A1W4X127   F4WIW5   E9II25   A0A023GNM9   A0A1B6HBY6   A0A0J7NL13   A0A310SFW9   E1ZW07   A0A1B6LAF8   A0A1E1XDX6   A0A1B6FYL8   T1IY23   A0A154P122   A0A195CU11   A0A0L7RFD7   H0ZPL5   A0A0N0BBN7   A0A218V091   B7PDC5   A0A151WLH7   A0A026WY24   A0A1V4JLZ9   A0A091T0C8   T1JHV9   A0A151IXQ0   E2B9Q7   A0A0Q3UTU4  

EC Number

6.3.5.7

Pubmed

19121390    22118469    26227816    26354079    28756777    17994087    + More
15632085    26108605    24495485    17550304    10731132    12537572    12537569    25315136    17510324    26483478    12364791    20920257    23761445    20966253    25244985    24438588    18362917    19820115    28648823    20075255    28004739    23537049    26830274    28797301    25576852    21719571    21282665    20798317    28503490    20360741    24508170    30249741   

EMBL

BABH01016560    ODYU01002556    SOQ40224.1    AGBW02012241    OWR45366.1    JTDY01000481    + More
KOB76990.1    KQ461003    KPJ10011.1    KQ459601    KPI93664.1    NWSH01000657    PCG74984.1    KZ149908    PZC78236.1    RSAL01000369    RVE42158.1    OUUW01000007    SPP82551.1    CH902617    EDV43646.1    CH940656    EDW58583.1    CM000070    CH933806    EDW16227.1    CH479186    EDW39123.1    JRES01000657    KNC29477.1    DS231871    CH480892    EDW55432.1    CH964272    EDW83639.1    CH954181    EDV48533.1    GAMC01001947    JAC04609.1    CM000364    EDX12384.1    CP012526    ALC47163.1    CH916377    EDV90766.1    BT133209    AFA28450.1    CM000160    EDW95977.1    AE014297    AY061613    GFDL01011678    JAV23367.1    CH477252    CVRI01000048    CRK98789.1    JXUM01003476    KQ560159    KXJ84113.1    GDHF01021003    JAI31311.1    AAAB01008817    APCN01002617    ADMH02002102    ETN59100.1    ATLV01016349    KE525079    KFB41231.1    AXCN02001191    KQ971342    EFA03686.1    NNAY01000698    OXU26925.1    GEZM01070640    JAV66371.1    AJWK01009713    APGK01021752    APGK01021753    APGK01021754    KB740358    KB631949    ENN80814.1    ERL87418.1    GEDV01002385    JAP86172.1    GFPF01006135    MAA17281.1    GACK01006765    JAA58269.1    GL888177    EGI65911.1    GL763347    EFZ19768.1    GBBM01000893    JAC34525.1    GECU01035482    JAS72224.1    LBMM01003786    KMQ93135.1    KQ768478    OAD53139.1    GL434713    EFN74629.1    GEBQ01019294    JAT20683.1    GFAC01001820    JAT97368.1    GECZ01014491    JAS55278.1    JH431669    KQ434796    KZC05626.1    KQ977279    KYN04178.1    KQ414608    KOC69436.1    ABQF01000466    KQ435970    KOX67811.1    MUZQ01000087    OWK59032.1    DS689337    KQ982959    KYQ48670.1    KK107077    QOIP01000001    EZA60616.1    RLU27107.1    LSYS01006902    OPJ73226.1    KK494304    KFQ64747.1    JH431998    KQ980796    KYN12972.1    GL446584    EFN87591.1    LMAW01000836    KQK85274.1   

Proteomes

UP000005204    UP000007151    UP000037510    UP000053240    UP000053268    UP000218220    + More
UP000283053    UP000268350    UP000007801    UP000008792    UP000001819    UP000009192    UP000008744    UP000192221    UP000037069    UP000002320    UP000001292    UP000007798    UP000008711    UP000000304    UP000092553    UP000001070    UP000002282    UP000000803    UP000095301    UP000095300    UP000008820    UP000183832    UP000069940    UP000249989    UP000075880    UP000075900    UP000075903    UP000076407    UP000069272    UP000007062    UP000075840    UP000000673    UP000075882    UP000076408    UP000075920    UP000030765    UP000075901    UP000075884    UP000075885    UP000075886    UP000075881    UP000007266    UP000215335    UP000002358    UP000092461    UP000019118    UP000030742    UP000192223    UP000007755    UP000036403    UP000000311    UP000076502    UP000078542    UP000053825    UP000007754    UP000053105    UP000197619    UP000001555    UP000075809    UP000053097    UP000279307    UP000190648    UP000078492    UP000008237    UP000051836   

PRIDE

H9JMN8    B0WAE3    Q9VE09    Q17H91    B7PDC5   

Pfam

PF01425   Amidase

Interpro

IPR036928   AS_sf        + More
IPR004412   GatA       
IPR000120   Amidase       
IPR023631   Amidase_dom       

SUPFAM

SSF75304   SSF75304       

Gene 3D

3.90.1300.10    

ProteinModelPortal

H9JMN8   A0A2H1VJ00   A0A212EV54   A0A0L7LNI1   A0A0N1PF89   A0A194PLQ4   + More
A0A2A4JTP0   A0A2W1BZT4   A0A3S2N5M0   A0A3B0KBW5   B3LVB4   B4MBW2   Q29BT3   B4K5Z0   B4GPP0   A0A1W4UPQ1   A0A0L0CB66   B0WAE3   B4ILV6   B4NHY9   B3P381   W8C564   B4QTW1   A0A0M3QY70   B4JYK4   H5V8A8   B4PMQ7   Q9VE09   A0A1I8MZ60   A0A1Q3F751   A0A1I8PPZ0   Q17H91   A0A2K7P689   A0A1J1IEV0   A0A182GXB9   A0A0K8UXK0   A0A182JN09   A0A182RBK1   A0A182VBM5   A0A182XFF8   A0A182FXF8   Q7QH64   A0A182I843   W5J8A2   A0A182L7R2   A0A182YF37   A0A182VX24   A0A084VTD7   A0A182T1L4   A0A182NKS4   A0A182P455   A0A182QRT8   A0A182JVJ5   D6WJE7   A0A232F8D4   K7J1T3   A0A1Y1L0R6   A0A1B0CF56   N6TK20   A0A131Z5V6   A0A224YRR3   L7M5A1   A0A1W4X127   F4WIW5   E9II25   A0A023GNM9   A0A1B6HBY6   A0A0J7NL13   A0A310SFW9   E1ZW07   A0A1B6LAF8   A0A1E1XDX6   A0A1B6FYL8   T1IY23   A0A154P122   A0A195CU11   A0A0L7RFD7   H0ZPL5   A0A0N0BBN7   A0A218V091   B7PDC5   A0A151WLH7   A0A026WY24   A0A1V4JLZ9   A0A091T0C8   T1JHV9   A0A151IXQ0   E2B9Q7   A0A0Q3UTU4  

PDB

4WJ3     E-value=1.59168e-82,     Score=782

KEGG

101746315    K02433 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] | (RefS

PATHWAY

00970    Aminoacyl-tRNA biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0070681   GO:0005739   GO:0030956   GO:0032543   GO:0004040   GO:0005524   GO:0050567   GO:0016740   GO:0030717   GO:0006412   GO:0048477   GO:0031647   GO:0051536   GO:0051537   GO:0043565   GO:0003677   GO:0003707   GO:0006281   GO:0006259  

PANTHER

PTHR11895  

Subcellular location

Mitochondrion  

Length:

669

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.24762

Exp number, first 60 AAs:

0.00124

Total prob of N-in:

0.01212

outside

1  -  669

 

 

Pi

235.837643

Theta

189.747976

Tajima's D

0.686397

CLR

15.530454

CSRT

0.569821508924554

Interpretation

Uncertain