Gene

KWMTBOMO15456  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004754

Annotation

PREDICTED:_nuclear_pore_complex_protein_Nup133_[Bombyx_mori]

Location

Bomo_Chr25(+):14276411-14287308      View in EpiBrowser

Full name

Nuclear pore complex protein Nup133      

Alternative Name

133 kDa nucleoporin

Location in the cell

Cytoplasmic   Reliability : 1.531 PlasmaMembrane   Reliability : 1.243

CDS

ATGCAGTCACAAAGCGAACAAACTGGCGATGTGATCTATAAAACTCCATCGATGACACTAGAAACGTACGGGGCACCTATGCCAGTGATGGTCACAGAGGCTCTTGCGTTCGCAAGTGGAGACATCTCAGTGCGCCTCTCGACCTGTGGCTGGTGTTGGGTAGTGTCTGGTCGTCGCATCCTGGCTTGGGAGCAATCTCCAATAGATACTGATGAAGATCCAGCCAATGTGACTGGCATATCAGCTGCTCGAGAGCTCACATTACCTCAAACAGATTTAGCTCACAAGGCTGATTTAGTTGTACTGTTTTATGGAAATGACTCTCAGATGCCATCCTGTATTGGAGTTTCACCTGAGGGTGTGATTCGCTACTGGCCCTCAGTAGGACAAGAAGAGGTTTATGTAGATGTAACATGTGAACTAGCAGGTCAAGAGTGTGAGAAACTAGGAGATTACACCAGCTCTGGCCTCATACTGGCTACTACGACTTGTACCGTGGTGCTATTGACTCCTACTGTTCTTGATGGAAGAGCAACAGTGACTTGCTGCACTTTACGTCCACCGAGTGGTTGGCTAGGAGGTATAGGACGACGTGTATCACTGTTGTTCTTTGGATCTATGCCTGCACACACAGATACGCGGCTGGTGGGTGCGGTGTGGGCGGGGGACTGCGTGTGGCTGGTGGCTCGCGGGCCAACGCTGCAGGTGTGGCGCCCTCCCGCGCTGCTGCACCACCACTCGCTGCGGGGCCCGCTGGCGCTCGCCGCGCGCCCGCATCTGCAGCCTCACGGTGACTTGAACAGCTTGGAGATAATGGCTCTGGATGTGCAGGCCAGTGGGAACGATGGCTTCTTGCTACTAATCGCAGCAGTTAATGTAACGAGGTCACCGGAAATGAGATATGCTATTGCTCACATCAACGTAGAAGATCCATCGTCTCCTCGTGTAAGTTCATTTGTTCCTGTCCGGAATTTTCCTCAGGAAGCGGATGAGCCTCCGCGGCTTTTGCCCTTCGGAAACAAAGCGTTATTGTATACATCCAAATACATCGCTTTGATTTCACTAGCAGCCACGACGGACGCTGAAGTTGTGGAGGCGGCCAGTGGAGACCGCGTGCTCAGCGCCGCGCGCTCCCCGCACGGACCCGCGCTGTTCACCGCCGCGCACGGCCTGCTCGCACTGCGTCTGCACTCGCACGCCGCAGCTGCATGTGACAGTCCGATCGGCTCCTCGAGTCAAGCTGACATGTATGAAGGAAATTTATCGCTGTACGAAATTGATCCTTGCGAGATGAGCGCGGTGGTGACGGACGCGTGCGGGAAACTGAAGACGGCCTTCCTGTTCCACCTGCGGCGGGACTTCACCTCGTGCCGCGAGCTGCTGGACGAGCTGTTCCCGCCGCCCGGCCAGCACGCGCCGCAGGAGCTCGACGTGGACGCGCCCCTGGACCGCACCGTGCTCGCCGTGGCCACCGAGACGCTGGACGACATGCCCGCGGGGGATCCTAGGTGGAAGCGCTCGAGCGGACAGCCCACCCACATCCCGCTGGGCAGCTCCACGGCGCTGCAGATAGAAGCCCAGCTCCTGGACAAGCAGAGAGCGCTGGCACTCTTCTTCGACTTCCTGAGAGCGACCGGCCTGTGGCAGAGGTTGGGCCTCGTCACTGTAGAGGACGAGGGCGTGGCCAGCACCACGAGCGCGCTGTGCCAGGCCTGGGAGCGCGTGCGCGGCGCCGCGGCCCTGCGCCGCCTGCAGCGGGGGACCCACGCCGCCTTCATAGACTCCATTATATGTGAGGCGGTGCGCGGCTGGCAACACCGCGAGGAGGAGAGCGTGCACGCGGCGCTGTCCAGTGGCGCGCTGTCCCCGACGGACGCGTGCTACCGTCGCGTGTCCCGCCTGCCAGCCGTGCTGCTGATGCTCACCCGGCCCGTGCCGTCCGACCGCCCGGCGGCGCTTGCCGTGCTTAGTGGCGTGCTATCGGAGATGCTGAAGGCTCGCAAGTCGTGGCAGAACGTGTCGCCGCCCCCGCTGGGCTCCTCGGCGCTGCTCACCCCCGCGCTGCACCTCATCAGGAAGAGTCTCACTGAATTCGAGAACAAGGGGGGCGATGCGACGCTGCGCGCGCAGGTGTGCGAGGCGGCCGCGGGGCTGGCCGACGTGCTGCTGGCCGGCGCGCAGGCCTCCCCCGCCTACCCCGCGCTGCGCACCGACCTCATCCGCCCCTTCGTGGAGCAGGGGGAGCCGGAGCGCGCGGCGGCCCTGGCGGAGAAGTACCAGGAGTTCTCCGTGCTGGTGGAGCTGTGCGTGTCGGGCGGCGACACGGCGCGCCTGTGCGACTACGTGGACCGGTACAGCGACCGCGGTATGGCGGAGGTCGCGTACGAGTGGATGTCGCGCAAGGGTGGCGCCGCCGCCGCCGCCCTCGTCAGAGGCGCTGGGGGCGGAGCCCGGCTGACGGCGTGGCTGCGGCGGGAGCGCCCCGACCTGCTGTCGCTGCACCAGCTGCACCGCGGGGACCACGCCGCCGCCGCGCAAACCTTCAGCAGCCTCGCGCACGCTGAGACCGACAACCTCGAGCGGATGACGACGCTGGCGTCCCTGAGCAAGCTGTGCATGCTGGTGTCGGACGCGCCGGAGGAGGCCCCGGCGTGGGACGCCGTGCAGCGCCGCCTGGCCCTCGCCGAGCAGCACCGCGCCCTGCCCCGTGACGTCATGCCCAGTGACGTCACGCCGCAGCGCGTCATGCAGCCCCACGAGCTCGTCGAGGTGTACCTAAAAGCTGAGAACAAATCGTTGACTGAATACGACTACAAGAAGGCGCTGGACCTGACGGAGGGCGTGGAGGACCCCGAGCAGCGGCAGCGGCTGCGCCTGCGGGTGTGGTGCGCCAGCGTGCTGCGCGACGACTGGGCCGCCTGCAAGCCGGACGACCCCGCCGCCGAGCTCATGCAGAGGACCTTCTTCAAGCTCATAGACCTCGTCAACGTCATGGGCGACGACCTGGACGTGCTGCTGCCCGAGCTCCCCGAGCTGCTGTCGGCGCCGGAGCTGGCCGCGCTGGCTGCGGACTCCAAGTTCCACTACCTCCTCAAGTACGGGTACGAGTGCCTCCACCAGCGCACCGCGGACCAGAGCCCTGATGACTCTGCTTGA

Protein

MQSQSEQTGDVIYKTPSMTLETYGAPMPVMVTEALAFASGDISVRLSTCGWCWVVSGRRILAWEQSPIDTDEDPANVTGISAARELTLPQTDLAHKADLVVLFYGNDSQMPSCIGVSPEGVIRYWPSVGQEEVYVDVTCELAGQECEKLGDYTSSGLILATTTCTVVLLTPTVLDGRATVTCCTLRPPSGWLGGIGRRVSLLFFGSMPAHTDTRLVGAVWAGDCVWLVARGPTLQVWRPPALLHHHSLRGPLALAARPHLQPHGDLNSLEIMALDVQASGNDGFLLLIAAVNVTRSPEMRYAIAHINVEDPSSPRVSSFVPVRNFPQEADEPPRLLPFGNKALLYTSKYIALISLAATTDAEVVEAASGDRVLSAARSPHGPALFTAAHGLLALRLHSHAAAACDSPIGSSSQADMYEGNLSLYEIDPCEMSAVVTDACGKLKTAFLFHLRRDFTSCRELLDELFPPPGQHAPQELDVDAPLDRTVLAVATETLDDMPAGDPRWKRSSGQPTHIPLGSSTALQIEAQLLDKQRALALFFDFLRATGLWQRLGLVTVEDEGVASTTSALCQAWERVRGAAALRRLQRGTHAAFIDSIICEAVRGWQHREEESVHAALSSGALSPTDACYRRVSRLPAVLLMLTRPVPSDRPAALAVLSGVLSEMLKARKSWQNVSPPPLGSSALLTPALHLIRKSLTEFENKGGDATLRAQVCEAAAGLADVLLAGAQASPAYPALRTDLIRPFVEQGEPERAAALAEKYQEFSVLVELCVSGGDTARLCDYVDRYSDRGMAEVAYEWMSRKGGAAAAALVRGAGGGARLTAWLRRERPDLLSLHQLHRGDHAAAAQTFSSLAHAETDNLERMTTLASLSKLCMLVSDAPEEAPAWDAVQRRLALAEQHRALPRDVMPSDVTPQRVMQPHELVEVYLKAENKSLTEYDYKKALDLTEGVEDPEQRQRLRLRVWCASVLRDDWAACKPDDPAAELMQRTFFKLIDLVNVMGDDLDVLLPELPELLSAPELAALAADSKFHYLLKYGYECLHQRTADQSPDDSA

Description

Probable component of the nuclear pore complex (NPC) (Probable). Plays a role in NPC assembly and/or maintenance (PubMed:20547758).

Subunit

Forms part of the Nup107-Nup160 subcomplex in the nuclear pore.

Similarity

Belongs to the nucleoporin Nup133 family.
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

Keywords

Complete proteome   mRNA transport   Nuclear pore complex   Nucleus   Protein transport   Reference proteome   Translocation   Transport  

Feature

chain  Nuclear pore complex protein Nup133

Uniprot

A0A3S2P298   A0A212EVZ1   A0A2J7RA04   E0VYF6   A0A1B0CE80   K7J5T7   + More
A0A088A0Z5   A0A0L7QUQ5   A0A232EZI1   A0A2A3EN61   A0A0C9R9D3   A0A0M8ZYZ0   A0A1B6E0K1   E2BNB0   V4AAF7   U4U868   F4WA61   A0A158NHL0   A0A1I8NVE6   A0A1I8NVD9   A0A1I8NBJ4   A0A0A1WDU8   A1YK82   A0A182YLM2   A1YK81   A1YK79   A1YK83   A1YK85   A1YK77   Q9VCW3   A1YK80   A1YK78   A1YK86   E9FWZ0   A0A0P5MHN3   A0A0P5LZ98   A0A0P4XQF8   A0A0P5QA91   B4HER9   A1YK95   A1YK92   A1YK88   A1YK98   A1YK96   A0A1A9YIY0   A1YK94   A1YK97   A1YKA0   A1YK91   B4KBB3   A1YK89   B4PMD6   A1YK90   B4JRZ7   A0A1A9VQY3   A0A0M4F7F2   A0A0J7KD42   A0A0K8WAZ8   A0A0P5YWY4   B4M641   A0A131YL41   A0A2T7PFZ6   A0A2C9JQH2   A0A336M2M2   A0A293M9N9   A0A224YDA6   A0A034VG90   A0A0P6I4Z1   A0A0P5CMP7   A0A0P5VQ99   A0A0P6C8Q9   A0A0N8DD69   A0A0B7AV36   A0A0P5JC23   A0A0P5AEK7   A0A0P5JAB7   A0A0P5MDD3   A0A0P5IYI0   A0A0P5J5G0   A0A195ETN2   A0A195AUP7   G1K922   A0A151M2P4   A0A3B3S8N1  

Pubmed

22118469    20566863    20075255    28648823    20798317    23254933    + More
23537049    21719571    21347285    25315136    25830018    17056646    25244985    10731132    12537572    12537569    20547758    21292972    17994087    17550304    26830274    15562597    28797301    25348373    22293439    29240929   

EMBL

RSAL01000001    RVE55286.1    AGBW02012106    OWR45653.1    NEVH01006580    PNF37667.1    + More
DS235845    EEB18412.1    AJWK01008657    AAZX01003923    KQ414735    KOC62309.1    NNAY01001572    OXU23558.1    KZ288215    PBC32579.1    GBYB01013014    JAG82781.1    KQ435821    KOX72473.1    GEDC01005859    JAS31439.1    GL449385    EFN82872.1    KB202163    ESO92060.1    KB631792    ERL86140.1    GL888041    EGI68917.1    ADTU01015920    GBXI01017113    JAC97178.1    EF058005    EF058007    ABL84940.1    ABL84942.1    EF058004    ABL84939.1    EF058002    ABL84937.1    EF058006    ABL84941.1    EF058008    ABL84943.1    EF058000    ABL84935.1    AE014297    BT003226    AY051721    AAK93145.1    AAO24981.1    EF058003    EF058010    ABL84938.1    ABL84945.1    EF058001    ABL84936.1    EF058009    ABL84944.1    GL732526    EFX88351.1    GDIQ01158058    GDIQ01034998    JAK93667.1    GDIQ01173640    JAK78085.1    GDIP01240567    JAI82834.1    GDIQ01123022    JAL28704.1    CH480815    EDW43230.1    EF058018    ABL84953.1    EF058015    ABL84950.1    EF058011    ABL84946.1    EF058021    ABL84956.1    EF058019    ABL84954.1    EF058017    ABL84952.1    EF058020    EF058022    ABL84955.1    ABL84957.1    EF058023    ABL84958.1    EF058014    ABL84949.1    CH933806    EDW16841.1    EF058012    EF058016    ABL84947.1    ABL84951.1    CM000160    EDW98041.1    EF058013    ABL84948.1    CH916373    EDV94537.1    CP012526    ALC47782.1    LBMM01009259    KMQ88267.1    GDHF01003951    JAI48363.1    GDIP01052539    LRGB01001361    JAM51176.1    KZS12347.1    CH940652    EDW59117.1    GEDV01009926    JAP78631.1    PZQS01000004    PVD32345.1    UFQT01000114    SSX20218.1    GFWV01012337    MAA37066.1    GFPF01004542    MAA15688.1    GAKP01018172    JAC40780.1    GDIQ01009414    JAN85323.1    GDIP01168309    JAJ55093.1    GDIP01096929    JAM06786.1    GDIP01019209    JAM84506.1    GDIP01045295    JAM58420.1    HACG01037873    CEK84738.1    GDIQ01227180    JAK24545.1    GDIP01213171    JAJ10231.1    GDIQ01204784    JAK46941.1    GDIQ01165552    JAK86173.1    GDIQ01207645    JAK44080.1    GDIQ01206289    JAK45436.1    KQ981975    KYN31598.1    KQ976737    KYM75963.1    AKHW03006780    KYO18784.1   

Proteomes

UP000283053    UP000007151    UP000235965    UP000009046    UP000092461    UP000002358    + More
UP000005203    UP000053825    UP000215335    UP000242457    UP000053105    UP000008237    UP000030746    UP000030742    UP000007755    UP000005205    UP000095300    UP000095301    UP000076408    UP000000803    UP000000305    UP000001292    UP000092443    UP000009192    UP000002282    UP000001070    UP000078200    UP000092553    UP000036403    UP000076858    UP000008792    UP000245119    UP000076420    UP000078541    UP000078540    UP000001646    UP000050525    UP000261540   

PRIDE

A1YK82    A1YK81    A1YK79    A1YK83    A1YK85    A1YK77    + More
Q9VCW3    A1YK80    A1YK78    A1YK86   

Pfam

PF08801   Nucleoporin_N        + More
PF03177   Nucleoporin_C
PF01189   Methyltr_RsmB-F

Interpro

IPR037624   Nup133-like        + More
IPR014908   Nucleoporin_Nup133/Nup155_N       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR007187   Nucleoporin_Nup133/Nup155_C       
IPR001678   MeTrfase_RsmB/NOP2       
IPR029063   SAM-dependent_MTases       
IPR023267   RCMT       

SUPFAM

SSF53335   SSF53335       

Gene 3D

2.130.10.10    

ProteinModelPortal

A0A3S2P298   A0A212EVZ1   A0A2J7RA04   E0VYF6   A0A1B0CE80   K7J5T7   + More
A0A088A0Z5   A0A0L7QUQ5   A0A232EZI1   A0A2A3EN61   A0A0C9R9D3   A0A0M8ZYZ0   A0A1B6E0K1   E2BNB0   V4AAF7   U4U868   F4WA61   A0A158NHL0   A0A1I8NVE6   A0A1I8NVD9   A0A1I8NBJ4   A0A0A1WDU8   A1YK82   A0A182YLM2   A1YK81   A1YK79   A1YK83   A1YK85   A1YK77   Q9VCW3   A1YK80   A1YK78   A1YK86   E9FWZ0   A0A0P5MHN3   A0A0P5LZ98   A0A0P4XQF8   A0A0P5QA91   B4HER9   A1YK95   A1YK92   A1YK88   A1YK98   A1YK96   A0A1A9YIY0   A1YK94   A1YK97   A1YKA0   A1YK91   B4KBB3   A1YK89   B4PMD6   A1YK90   B4JRZ7   A0A1A9VQY3   A0A0M4F7F2   A0A0J7KD42   A0A0K8WAZ8   A0A0P5YWY4   B4M641   A0A131YL41   A0A2T7PFZ6   A0A2C9JQH2   A0A336M2M2   A0A293M9N9   A0A224YDA6   A0A034VG90   A0A0P6I4Z1   A0A0P5CMP7   A0A0P5VQ99   A0A0P6C8Q9   A0A0N8DD69   A0A0B7AV36   A0A0P5JC23   A0A0P5AEK7   A0A0P5JAB7   A0A0P5MDD3   A0A0P5IYI0   A0A0P5J5G0   A0A195ETN2   A0A195AUP7   G1K922   A0A151M2P4   A0A3B3S8N1  

PDB

3I4R     E-value=1.71517e-20,     Score=249

KEGG

101742485    K14300 nuclear pore complex protein Nup133 | (RefSeq) nuclear pore complex protein Nup133

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0005623   GO:0017056   GO:0006406   GO:0031080   GO:0031081   GO:0006606   GO:0016020   GO:0008168   GO:0003723   GO:0061053   GO:0000940   GO:0006999   GO:0022008   GO:0048339   GO:0021915   GO:0031965   GO:0072006   GO:0005515   GO:0005524   GO:0005694   GO:0051276   GO:0030145   GO:0043565   GO:0003677   GO:0003707   GO:0006281   GO:0006259  

PANTHER

PTHR13405  

Subcellular location

   Located on both the cytoplasmic and nuclear sides of the nuclear pore.   With evidence from 1 publications.

Length:

1051

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.386760000000001

Exp number, first 60 AAs:

0.12676

Total prob of N-in:

0.01718

outside

1  -  1051

 

 

Pi

172.952746

Theta

18.993003

Tajima's D

-1.110189

CLR

1.454577

CSRT

0.116994150292485

Interpretation

Uncertain