Gene

KWMTBOMO15381

Annotation

PREDICTED:_trypsin-2-like_[Bombyx_mori]

Location

Bomo_Chr25(-):10884667-10887155      View in EpiBrowser

Full name

Hypodermin-A      

Location in the cell

Extracellular   Reliability : 1.994

CDS

ATGTTTCCTCATTCAACTTATCTAAGTATTCCATGTGAAGGTAATTTCATGTGTGGTTCTTCAGTTTTGGGCCAAAATGTTCTTCTAACGGCGGCTCATTGTGTATGCAACTGTAATTTAAGAAAAAACAGATTAGAAGCTCTAGCTGGACATGCGTTAATCAAAAAGATGACTCTTCGACGGAGTGTTACGGCTATGACAGTTCATGCAAAGTATAATGAAAAAACAATAGAAAATGACATAGCAATATTATGGCTCGATCGTAGATTATTGTTTGGGGATAACGTGAAACGCGTTATAATTACAAAAACATTTCCATTCACAACCGAAGCCTGTATCGCTGGCTGGGGACTTATTAACGTGAGTAAAACCACTTGA

Protein

MFPHSTYLSIPCEGNFMCGSSVLGQNVLLTAAHCVCNCNLRKNRLEALAGHALIKKMTLRRSVTAMTVHAKYNEKTIENDIAILWLDRRLLFGDNVKRVIITKTFPFTTEACIAGWGLINVSKTT

Similarity

Belongs to the peptidase S1 family.

Keywords

Direct protein sequencing   Disulfide bond   Hydrolase   Protease   Secreted   Serine protease   Signal   Zymogen  

Feature

propeptide  Activation peptide
chain  Hypodermin-A

Uniprot

A0A194Q913   A0A194QDC4   A0A194RKI2   A0A212FK82   A0A212FKP7   A0A2H1V9I9   + More
A0A2H1VHC8   A0A2A4JL27   A0A2H1WKW7   A0A212FKM8   A0A2H1W4Q5   A0A0L7LFE7   A0A2H1VR93   B0WLB8   A0A0L7KT34   A0A0T6B7T2   A0A2W1BJQ7   A0A3P9DN47   W5JDQ9   B3MWA2   A0A3Q3M8B3   A0A3S2P785   A0A0L7LG02   A0A3B5AUC8   A0A0L7KVC9   A0A1Q3FSI0   A7DYY1   A7DYX9   A7DYX7   B4Q817   Q5QBG3   A0A3S2LBD0   A0A3P8WLP4   A0A1I8Q6S0   A0A3B5AKI3   A0A3B5AW50   H2UD15   A0A3Q3LWL8   A0A3Q3M853   A0A3B5AME9   A7DYY0   H9J0R7   B4I2H7   I3KBF0   A0A3B5AMM2   A0A3B5AKR2   A0A3B4T346   A0A3P8PL82   A0A3Q3LWK4   A0A182GGY4   A0A1W7R806   Q9VXC9   Q0GSU5   A0A1L3J040   A0A1Q3FPS2   A0A226EAL5   B3NVL1   A0A067R782   B4IER6   A0A1A9W2J2   A0A0B7K512   A0A3B5AKU5   A0A1Q3FQJ5   A0A1L3J026   A0A1L3J025   A0A1L3J024   A0A1L3J041   A0A1L3J065   A0A2I0U4S9   A0A1A9W0A9   A0A1L3J049   A0A3M6U1N3   A0A1Y1KBN6   Q17IG9   H9J0R6   Q175P6   A7DYX6   A0A1W4W8M1   A7DYX5   A0A182GAC9   A0A1L9WNS2   A0A2U9C0F9   A0A1Q3FNA4   A0A1L3J027   Q5BAR4   A0A1U8QWP9   A0A1L3J028   B4R616   A0A1L3J018   A0A1L3J034   A0A3Q1GSD3   A0A3Q4GW67   A0A099ZLA0   A0A3Q1FUL4   A7DYV9   A0A1W4XLZ4   A0A0L7LF91   A0A182IT30   P35587   A0A1L3J044  

EC Number

3.4.21.-

Pubmed

26354079    22118469    26227816    28756777    25186727    20920257    + More
23761445    17994087    17573377    22936249    15796745    24487278    21551351    19121390    26483478    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    16783023    27883252    24845553    30382153    28004739    17510324    28196534    16372000    19146970    7808473    7018579   

EMBL

KQ459324    KPJ01455.1    KPJ01456.1    KQ460045    KPJ18047.1    AGBW02008116    + More
OWR54136.1    AGBW02008010    OWR54306.1    ODYU01001393    SOQ37513.1    ODYU01002383    SOQ39812.1    NWSH01001202    PCG72143.1    ODYU01009360    SOQ53730.1    OWR54305.1    ODYU01006324    SOQ48069.1    JTDY01001347    KOB74130.1    ODYU01003944    SOQ43317.1    DS232962    DS231983    EDS27062.1    EDS30402.1    JTDY01006244    KOB66174.1    LJIG01009274    KRT83408.1    KZ150000    PZC75312.1    ADMH02001669    ETN61483.1    CH902625    EDV35247.1    RSAL01000249    RVE43502.1    KOB74131.1    JTDY01005274    KOB67168.1    GFDL01004672    JAV30373.1    AM765883    CAO78784.1    AM765881    CAO78782.1    AM765879    AM765880    CAO78780.1    CAO78781.1    CM000361    CM002910    EDX03439.1    KMY87631.1    AY752848    AAV84261.1    RSAL01000282    RVE43013.1    AM765882    CAO78783.1    BABH01010245    CH480820    EDW53972.1    AERX01014184    AERX01014185    JXUM01062824    KQ562217    KXJ76377.1    GEHC01000378    JAV47267.1    AE014298    AY118432    AAF48647.1    AAM48461.1    DQ539257    DQ539259    DQ539260    ABG02778.1    ABG02780.1    ABG02781.1    KY087128    KY087137    APG58489.1    GFDL01005572    JAV29473.1    LNIX01000005    OXA54258.1    CH954180    EDV46403.1    KK852655    KDR19292.1    CH480832    EDW46170.1    CDPU01000028    CEO52428.1    GFDL01005165    JAV29880.1    KY087112    APG58473.1    KY087106    KY087108    KY087111    KY087113    KY087117    KY087126    KY087136    KY087140    APG58472.1    KY087107    KY087139    APG58468.1    KY087134    APG58495.1    KY087143    APG58504.1    KZ506167    PKU41078.1    KY087138    APG58499.1    RCHS01002416    RMX47449.1    GEZM01091341    JAV56896.1    CH477239    EAT46500.1    BABH01010242    BABH01010243    CH477397    EAT41804.1    AM765878    CAO78779.1    AM765877    CAO78778.1    JXUM01008849    KQ560270    KXJ83415.1    KV878981    OJJ97808.1    CP026253    AWP09961.1    GFDL01006008    JAV29037.1    KY087110    KY087115    KY087127    KY087141    APG58476.1    BN001307    CBF86700.1    AACD01000039    EAA64477.1    KY087105    KY087109    KY087121    KY087125    KY087135    APG58470.1    CM000366    EDX18120.1    KY087114    APG58475.1    KY087116    APG58477.1    KL895518    KGL82641.1    AM765861    CAO78762.1    KOB74132.1    X74303    L24914    KY087133    APG58494.1   

Proteomes

UP000053268    UP000053240    UP000007151    UP000218220    UP000037510    UP000002320    + More
UP000265160    UP000000673    UP000007801    UP000261640    UP000283053    UP000261400    UP000000304    UP000265120    UP000095300    UP000005226    UP000005204    UP000001292    UP000005207    UP000261420    UP000265100    UP000069940    UP000249989    UP000000803    UP000198287    UP000008711    UP000027135    UP000091820    UP000275408    UP000008820    UP000192221    UP000184546    UP000246464    UP000000560    UP000005890    UP000257200    UP000261580    UP000053641    UP000192223    UP000075880   

PRIDE

H9J0R7    Q9VXC9    Q0GSU5    H9J0R6    Q5BAR4   

Pfam

PF00089   Trypsin        + More
PF01390   SEA
PF00431   CUB
PF00057   Ldl_recept_a
PF00090   TSP_1

Interpro

IPR001254   Trypsin_dom        + More
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR018114   TRYPSIN_HIS       
IPR033116   TRYPSIN_SER       
IPR036364   SEA_dom_sf       
IPR035914   Sperma_CUB_dom_sf       
IPR036055   LDL_receptor-like_sf       
IPR002172   LDrepeatLR_classA_rpt       
IPR000859   CUB_dom       
IPR023415   LDLR_class-A_CS       
IPR000082   SEA_dom       
IPR000884   TSP1_rpt       
IPR036383   TSP1_rpt_sf       
IPR012224   Pept_S1A_FX       

SUPFAM

SSF50494   SSF50494        + More
SSF82671   SSF82671       
SSF57424   SSF57424       
SSF49854   SSF49854       
SSF82895   SSF82895       

Gene 3D

2.60.120.290     3.30.70.960     4.10.400.10     2.20.100.10    

CDD

cd00190  Tryp_SPc
cd00112  LDLa
cd00041  CUB

ProteinModelPortal

A0A194Q913   A0A194QDC4   A0A194RKI2   A0A212FK82   A0A212FKP7   A0A2H1V9I9   + More
A0A2H1VHC8   A0A2A4JL27   A0A2H1WKW7   A0A212FKM8   A0A2H1W4Q5   A0A0L7LFE7   A0A2H1VR93   B0WLB8   A0A0L7KT34   A0A0T6B7T2   A0A2W1BJQ7   A0A3P9DN47   W5JDQ9   B3MWA2   A0A3Q3M8B3   A0A3S2P785   A0A0L7LG02   A0A3B5AUC8   A0A0L7KVC9   A0A1Q3FSI0   A7DYY1   A7DYX9   A7DYX7   B4Q817   Q5QBG3   A0A3S2LBD0   A0A3P8WLP4   A0A1I8Q6S0   A0A3B5AKI3   A0A3B5AW50   H2UD15   A0A3Q3LWL8   A0A3Q3M853   A0A3B5AME9   A7DYY0   H9J0R7   B4I2H7   I3KBF0   A0A3B5AMM2   A0A3B5AKR2   A0A3B4T346   A0A3P8PL82   A0A3Q3LWK4   A0A182GGY4   A0A1W7R806   Q9VXC9   Q0GSU5   A0A1L3J040   A0A1Q3FPS2   A0A226EAL5   B3NVL1   A0A067R782   B4IER6   A0A1A9W2J2   A0A0B7K512   A0A3B5AKU5   A0A1Q3FQJ5   A0A1L3J026   A0A1L3J025   A0A1L3J024   A0A1L3J041   A0A1L3J065   A0A2I0U4S9   A0A1A9W0A9   A0A1L3J049   A0A3M6U1N3   A0A1Y1KBN6   Q17IG9   H9J0R6   Q175P6   A7DYX6   A0A1W4W8M1   A7DYX5   A0A182GAC9   A0A1L9WNS2   A0A2U9C0F9   A0A1Q3FNA4   A0A1L3J027   Q5BAR4   A0A1U8QWP9   A0A1L3J028   B4R616   A0A1L3J018   A0A1L3J034   A0A3Q1GSD3   A0A3Q4GW67   A0A099ZLA0   A0A3Q1FUL4   A7DYV9   A0A1W4XLZ4   A0A0L7LF91   A0A182IT30   P35587   A0A1L3J044  

PDB

2B9L     E-value=7.07119e-11,     Score=155

KEGG

101740349    no KO assigned | (RefSeq) trypsin-2-like

GO

GO:0004252   GO:0008236   GO:0016021   GO:0006508   GO:0005576   GO:0000150   GO:0000724   GO:0003690   GO:0003697   GO:0008094   GO:0005524   GO:0006281   GO:0006259  

Subcellular location

Secreted  

Length:

125

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.50515

Exp number, first 60 AAs:

0.2659

Total prob of N-in:

0.07775

outside

1  -  125

 

 

Pi

183.091815

Theta

161.573735

Tajima's D

1.693143

CLR

0

CSRT

0.823258837058147

Interpretation

Uncertain