Pre Gene Modal
BGIBMGA005089
Annotation
PREDICTED:_uncharacterized_protein_LOC101737844_isoform_X2_[Bombyx_mori]
Full name
ATP-dependent Clp protease proteolytic subunit
Location in the cell
Nuclear Reliability : 4.596
Sequence
CDS
ATGAGCAATGTAAATAATATTTCCAAGATGGGAGCAAAAGATAAAAACCTAAGATTGATATGTTCAACTCCAGAACAAAATAACAATTCTCCTTCAAGAGACAGTGATTCACTGTATGATTCAGATGCTACTAGTCCAGTTCCCTTTTTATGCACACAAGATGGAGCTGACGGAGAAACTGATGTTGTGTGGAATTTTTACACTCCGAAAGCTGATCGCAACAAAATTCATGATAAAAATGCAACACCCATTGGTAGGAAAGCTAAAAGAATTCAACGTCCAAAACTTATTGATAAACATATTTCAAAACGCAGAGCACTCCGTTCAACGCAGAAAAGAACAGAATTATTTAATGATCTTATTGAATTAAATCAAAACTTGTCTGAATTAATTAAAAAAAACCCTAAAGAGTCTGGTGTCAAAACCCATTCAGGTAGTGAAGAGGATTTATTTAGTGATTCATCTGATTATTCACCAAAAAGTGGACGAAAAACAAAACACAACTGCTTACGGAAAAATGTGTTAAGTTCAAAGTTTACTAAACCAGAGAATGAAAATGTGATAGAATCTGATGATTCAATGAATGAATGTTTGATCAAAGCCAGTCAAATTGTTGAAGACATTGCGTTTGATGATGAAGTAACCCCGCCAAAAGTAAATCCAGCAAAAAGGAAGTATGTTGATGTGAAAACTAATTATAATTCAATGGATACACTTTTAGGTAATGTAAAGCTAGGTTCACCAATAGTTAACAAAGTAAAGAAAAGTGAAATGCCATGCATTAACAATGACTCTTTTGATAATCTTGTTGAGAATTTGAATGACAGCGTATTCGAACAATTGACTCAAATGCCAGTTAAAATGGATGAAACTAACAAGACTGGTAGTAGTTGGAAAGTGAAAGAAGTTATAGTTCACAATGCAAGCCCCAAGTCATTGTCATTCATTCGACACAGCACTATGCCGGAATCACCATCACTGAATGTAAATAAACCTTCTACAAGTGGCATGGTCTTTGGCAGGTATAATACTATGCCAACTGAGAAGAATATCAGCAGTGGTGAATCTGATTGTTCACCAATAAAATGTACCCAAGAAGAAATAGAACGGAAACATCGGTTAGCCAGAGAAAAATTACTTGCCAAAAGTCTGCCAAAGTTACTGGGTATGATACCGATTGTAGTCGAACAAACTGGTAGAGGTGAGCGTGCATACGACATTTACTCGAGATTACTTCGCGAGAGAATCATATGTTTAATGGGGCCGATTAACGATGATATAAGTTCCTTGATCGTAGCACAATTACTATTCCTGCAGTCGGAGTCGAGTAAAAAGCCTGTCCATTTGTACATTAATTCTCCTGGTGGAGCTGTAACCGCTGGTCTCGGTATCTACGATACAATGCAGTACATCACTCCCCCAATAGCGACGTGGTGCGTCGGTCAGGCATGCAGCATGGCATCTTTGTTGCTGGCCGCTGGAGCCCCCGGAATGCGACACGCGCTACCTAACTCTCGGATCATGATACATCAGCCATCTGGAGGAGTACGAGGTCAAGCTACTGATATACAGATACAGGCGGAAGAGATTTTAAAACTGAAAGCACAAATAAATAATTTATATGTGAGACACACAGGCTTAGCGTTAGAGAAAGTGCAGTCGTCAATGGAGCGTGATTGTTTTATGTCCCCAATCGAAGCAAAGACCTTTGGTATAATAGACACTGTGTTAGAGCATCCTCCTTCACATGCTGTCGAACAGGAGTGTGCACCTAGTACTGCTACTAGTAGTAGTAATTGA
Protein
MSNVNNISKMGAKDKNLRLICSTPEQNNNSPSRDSDSLYDSDATSPVPFLCTQDGADGETDVVWNFYTPKADRNKIHDKNATPIGRKAKRIQRPKLIDKHISKRRALRSTQKRTELFNDLIELNQNLSELIKKNPKESGVKTHSGSEEDLFSDSSDYSPKSGRKTKHNCLRKNVLSSKFTKPENENVIESDDSMNECLIKASQIVEDIAFDDEVTPPKVNPAKRKYVDVKTNYNSMDTLLGNVKLGSPIVNKVKKSEMPCINNDSFDNLVENLNDSVFEQLTQMPVKMDETNKTGSSWKVKEVIVHNASPKSLSFIRHSTMPESPSLNVNKPSTSGMVFGRYNTMPTEKNISSGESDCSPIKCTQEEIERKHRLAREKLLAKSLPKLLGMIPIVVEQTGRGERAYDIYSRLLRERIICLMGPINDDISSLIVAQLLFLQSESSKKPVHLYINSPGGAVTAGLGIYDTMQYITPPIATWCVGQACSMASLLLAAGAPGMRHALPNSRIMIHQPSGGVRGQATDIQIQAEEILKLKAQINNLYVRHTGLALEKVQSSMERDCFMSPIEAKTFGIIDTVLEHPPSHAVEQECAPSTATSSSN
Summary
Catalytic Activity
Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
Similarity
Belongs to the peptidase S14 family.
Uniprot
EC Number
3.4.21.92
Pubmed
EMBL
Proteomes
PRIDE
Pfam
PF00574 CLP_protease
Interpro
SUPFAM
SSF52096
SSF52096
ProteinModelPortal
PDB
1TG6
E-value=1.60135e-88,
Score=833
Ontologies
GO
PANTHER
Topology
Length:
599
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.56849
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00492
outside
1 - 599
Population Genetic Test Statistics
Pi
266.984485
Theta
192.162494
Tajima's D
1.107813
CLR
0.487743
CSRT
0.684515774211289
Interpretation
Uncertain
