Gene

KWMTBOMO15323

Pre Gene Modal

BGIBMGA005064

Annotation

PREDICTED:_CXXC-type_zinc_finger_protein_1_[Amyelois_transitella]

Location

Bomo_Chr25(+):9108166-9113877      View in EpiBrowser

Full name

CXXC-type zinc finger protein 1      

Alternative Name

PHD finger and CXXC domain-containing protein 1

Location in the cell

Nuclear   Reliability : 4.651

CDS

ATGGGTGATAAAAAGTCGAGACAATCTAAAGCGGACATTGCTAAGCAGTTCGACTTGCCTGAACGCCAATCCAAAATTACAACATTGCTGAATCAAGCTGGACAAGCGTACTGCATTTGTCGATCTTCGGATAGTTCGCGATTTATGATAGCATGTGATGCATGCGAGGAATGGTATCATGGTGATTGTATCAACATTTCTGAGAGAGAATCAAAGTACATCAAGAATTACTTCTGTGACCGATGTAGAGAGGAAGATCCGACTTTGAAGACAAGGTTCAGACCACAAAAAAGAGAAAACGAGGTTGATTCTGGTCGAGATGATCGAAAAAAGCAGCGGAAAGAAAAGGATCATTCGGAAAATAAATCTTCCAAGAGAACTATAATAAAAGATGGTTGTGGAGATTGCCCTGGTTGCTTACAAGATTACGATTGTGGCCATTGTGATGCATGTGAGGAGATGTTCAAATATGGAAGTGCTAATAAAAAGTTCAGGTGCAAATTGAGAGTTTGTGTTAAAAGTAAAAAATCTTCTAAACCACCCAGCAGTAGCAGAATAAAGAAGAAGCATCATGAACGTGAACCGTATGAGCCAGAAGAATCGTTGGCGCATCTACAGACGGCGCATGCGCGTCAGTGCTACGGACCGCAGTGCACGTTGCCCGCTCGGTACTCCTCGAAGTACTGCTCCTCACAGTGCGGGATAAGGCTCGCCACTTCCCGGATATACCAAGTGCTCCCACAACGAATACAAGAATGGTCGTTGTCGAGCTGCGTTGCCGAACAGAAGAACCGCAAGGCACTAGAAGTGGTACGCAGCGGGATCGCTAAAGCGCAGGCCGCGCTGCGGAGTCTCGACAAACAGCACACAGATCTGGACGCACTGCTCGCCAAAGCTAAAAACGCTACAATTCTTCATACGGATGATAAGGACGCTGACGACGAAACCTCAATGTACTGCATAACGTGCGGCCACGAAATCCACTCGAGGACAGCCGTCAAACATATGGAGAAATGTTTTATAAAATACGAAGCGCAAGCGTCTTTCGGCAGTCGCCATAGGACGCGCATAGACGGACAAAGCATGTTCTGCGATTATTACAATCCTATCAATGCAACATATTGTAAGAGATTGAGGGTGATGTGTCCAGAACATTTTAAAGATTCCAAAGTGAGCGACAGCGATGTCTGCGGGTGTCCGCTGGTCCGCAACGTGTTCGATCCGTCGGGCGAGTTCTGCCGGGCGCCCAAGAAGTCGTGCTTGCGTCACTACCAGTGGGAGAAGCTGCGTCGAGCCGAGATAGACATGGAGAGGGTCCGGCAATGGTTGAAACTCGATGAACTTGTGGAACAGGAGCGTAGTATTAGATTGGCTATGGCTTCAAGAGCGGGCGTACTCGGTCTAATGCTACATTCTACTTACAACCACGAAGTCATGGAGCGAATCACAAATAAGGTTAACGAAAACGGGCTACACAAAGAAGGATCCTGA

Protein

MGDKKSRQSKADIAKQFDLPERQSKITTLLNQAGQAYCICRSSDSSRFMIACDACEEWYHGDCINISERESKYIKNYFCDRCREEDPTLKTRFRPQKRENEVDSGRDDRKKQRKEKDHSENKSSKRTIIKDGCGDCPGCLQDYDCGHCDACEEMFKYGSANKKFRCKLRVCVKSKKSSKPPSSSRIKKKHHEREPYEPEESLAHLQTAHARQCYGPQCTLPARYSSKYCSSQCGIRLATSRIYQVLPQRIQEWSLSSCVAEQKNRKALEVVRSGIAKAQAALRSLDKQHTDLDALLAKAKNATILHTDDKDADDETSMYCITCGHEIHSRTAVKHMEKCFIKYEAQASFGSRHRTRIDGQSMFCDYYNPINATYCKRLRVMCPEHFKDSKVSDSDVCGCPLVRNVFDPSGEFCRAPKKSCLRHYQWEKLRRAEIDMERVRQWLKLDELVEQERSIRLAMASRAGVLGLMLHSTYNHEVMERITNKVNENGLHKEGS

Description

Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3. Essential for Set1 association with chromatin and trimethylation of histone H3 at 'Lys-4' at transcription puffs. Additionally, is critical for general chromosomal association of Set1.

Subunit

Component of the SET1 complex, composed at least of the catalytic subunit Set1, wds/WDR5, Wdr82, Rbbp5, ash2, Cfp1/CXXC1, hcf and Dpy-30L1.

Similarity

Belongs to the GST superfamily.

Keywords

Complete proteome   DNA-binding   Metal-binding   Nucleus   Phosphoprotein   Reference proteome   Transcription   Transcription regulation   Zinc   Zinc-finger  

Feature

chain  CXXC-type zinc finger protein 1

Uniprot

H9J6C2   A0A2A4JU33   A0A212FKG5   A0A1E1WVA0   A0A194PHB2   A0A2H1W1Y7   + More
A0A2W1BBW1   A0A194RKK3   A0A3S2P355   A0A232F414   K7ITY5   A0A1Y1MSS3   A0A0C9RV07   A0A310SEV8   A0A2A3E514   A0A3L8E5P1   A0A087ZY49   A0A0T6ASX6   E2AND0   N6TTB1   F4WQ37   E2BJ22   A0A151JTY0   A0A151I5A6   A0A158NWV5   A0A195EDG7   A0A151IHN3   A0A151WYJ8   D6WK99   A0A0J7KG38   A0A182WAV5   A0A026W009   A0A1Q3G0Q7   A0A182LSA7   E9IVZ1   A0A084W1A8   W5JAR5   A0A182R2V6   A0A182YI78   A0A182URZ4   A0A182T4Q7   Q7Q2L7   A0A182KDH8   A0A182HGK5   A0A1B0CTT9   A0A182XPR0   A0A182NN75   A0A182QDT8   A0A182PMR1   A0A2M4BLR3   A0A067R2P3   U5ERT2   Q16PD3   A0A1B0D755   A0A2J7Q781   A0A2J7Q787   A0A347ZJ78   A0A1B6IJ58   A0A1B6DE16   A0A0K8UYE9   A0A1A9X8S0   A0A1B0BQQ2   A0A1A9ZK20   W8CD67   A0A1B0GA08   A0A034WMN8   E0W3Q2   A0A0A1WMX7   A0A1B6IKC3   A0A1A9WT15   A0A0L0CLE4   A0A2J7Q786   A0A1I8MLI0   A0A1I8NXS9   J9K8F3   A0A2S2PX77   A0A182TF02   A0A1W7R534   B4L1T5   W8BRV4   A0A0M8ZVV9   A0A0M5J7Z7   T1PAS0   B4NE15   B4GW83   A0A3B0JZI2   Q29IC4   B4JL68   B4PWV0   M9MS35   Q9W352   A0A0L7R0P5   B3NT84   B4R732   A0A1W4VUC8   A0A2R7WVS1   B3MZS1   A0A146M154   V4B1Y3  

Pubmed

19121390    22118469    26354079    28756777    28648823    20075255    + More
28004739    30249741    20798317    23537049    21719571    21347285    18362917    19820115    24508170    21282665    24438588    20920257    23761445    25244985    12364791    14747013    17210077    24845553    17510324    24495485    25348373    20566863    25830018    26108605    25315136    17994087    15632085    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17372656    21694722    21875999    26823975    23254933   

EMBL

BABH01019823    NWSH01000669    PCG74920.1    AGBW02008046    OWR54228.1    GDQN01000167    + More
JAT90887.1    KQ459604    KPI92438.1    ODYU01005768    SOQ46966.1    KZ150159    PZC72742.1    KQ460045    KPJ18067.1    RSAL01000037    RVE51161.1    NNAY01001085    OXU25193.1    GEZM01023896    JAV88158.1    GBYB01011496    JAG81263.1    KQ769812    OAD52835.1    KZ288369    PBC26780.1    QOIP01000001    RLU27615.1    LJIG01022882    KRT78243.1    GL441177    EFN65078.1    APGK01055164    KB741261    KB632344    ENN71571.1    ERL93051.1    GL888262    EGI63660.1    GL448558    EFN84172.1    KQ981799    KYN35692.1    KQ976434    KYM87202.1    ADTU01002984    KQ979074    KYN22857.1    KQ977586    KYN01683.1    KQ982651    KYQ52837.1    KQ971342    EFA03611.1    LBMM01008084    KMQ89161.1    KK107522    EZA49352.1    GFDL01001664    JAV33381.1    AXCM01000528    GL766449    EFZ15197.1    ATLV01019251    KE525266    KFB44002.1    ADMH02001922    ETN60493.1    AAAB01008968    EAA13256.4    APCN01009101    AJWK01027986    AXCN02001896    GGFJ01004854    MBW53995.1    KK853054    KDR12009.1    GANO01003587    JAB56284.1    CH477788    EAT36204.1    AJVK01026659    AJVK01026660    NEVH01017447    PNF24443.1    PNF24445.1    FX985646    BBA84384.1    GECU01020744    JAS86962.1    GEDC01013355    JAS23943.1    GDHF01020630    JAI31684.1    JXJN01018749    JXJN01024889    GAMC01002476    JAC04080.1    CCAG010018793    GAKP01003909    JAC55043.1    DS235882    EEB20258.1    GBXI01014251    GBXI01003746    JAD00041.1    JAD10546.1    GECU01020335    JAS87371.1    JRES01000325    KNC32269.1    PNF24444.1    ABLF02036897    GGMS01000309    MBY69512.1    GEHC01001385    JAV46260.1    CH933810    EDW06738.2    GAMC01002475    JAC04081.1    KQ435826    KOX72007.1    CP012528    ALC48568.1    KA645013    AFP59642.1    CH964239    EDW81984.1    CH479194    EDW26967.1    OUUW01000003    SPP78141.1    CH379063    EAL32729.2    CH916370    EDW00321.1    CM000162    EDX02834.2    AE014298    ADV37652.1    KQ414670    KOC64419.1    CH954180    EDV46264.2    CM000366    EDX17501.1    KK855720    PTY23644.1    CH902635    EDV33872.2    GDHC01006309    JAQ12320.1    KB203946    ESO82304.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000283053    + More
UP000215335    UP000002358    UP000242457    UP000279307    UP000005203    UP000000311    UP000019118    UP000030742    UP000007755    UP000008237    UP000078541    UP000078540    UP000005205    UP000078492    UP000078542    UP000075809    UP000007266    UP000036403    UP000075920    UP000053097    UP000075883    UP000030765    UP000000673    UP000075900    UP000076408    UP000075903    UP000075901    UP000007062    UP000075881    UP000075840    UP000092461    UP000076407    UP000075884    UP000075886    UP000075885    UP000027135    UP000008820    UP000092462    UP000235965    UP000092443    UP000092460    UP000092445    UP000092444    UP000009046    UP000091820    UP000037069    UP000095301    UP000095300    UP000007819    UP000075902    UP000009192    UP000053105    UP000092553    UP000007798    UP000008744    UP000268350    UP000001819    UP000001070    UP000002282    UP000000803    UP000053825    UP000008711    UP000000304    UP000192221    UP000007801    UP000030746   

PRIDE

H9J6C2    Q9W352   

Pfam

PF00628   PHD        + More
PF14497   GST_C_3
PF12269   zf-CpG_bind_C
PF02008   zf-CXXC
PF13417   GST_N_3
PF00379   Chitin_bind_4

Interpro

IPR004046   GST_C        + More
IPR036249   Thioredoxin-like_sf       
IPR036282   Glutathione-S-Trfase_C_sf       
IPR019786   Zinc_finger_PHD-type_CS       
IPR004045   Glutathione_S-Trfase_N       
IPR019787   Znf_PHD-finger       
IPR013083   Znf_RING/FYVE/PHD       
IPR037869   Spp1/CFP1       
IPR010987   Glutathione-S-Trfase_C-like       
IPR040079   Glutathione_S-Trfase       
IPR001965   Znf_PHD       
IPR005955   GST_Zeta       
IPR022056   CpG-bd_C       
IPR011011   Znf_FYVE_PHD       
IPR002857   Znf_CXXC       
IPR034330   GST_Zeta_C       
IPR000618   Insect_cuticle       

SUPFAM

SSF52833   SSF52833        + More
SSF47616   SSF47616       
SSF57903   SSF57903       

Gene 3D

3.30.40.10    

CDD

cd03191  GST_C_Zeta

ProteinModelPortal

H9J6C2   A0A2A4JU33   A0A212FKG5   A0A1E1WVA0   A0A194PHB2   A0A2H1W1Y7   + More
A0A2W1BBW1   A0A194RKK3   A0A3S2P355   A0A232F414   K7ITY5   A0A1Y1MSS3   A0A0C9RV07   A0A310SEV8   A0A2A3E514   A0A3L8E5P1   A0A087ZY49   A0A0T6ASX6   E2AND0   N6TTB1   F4WQ37   E2BJ22   A0A151JTY0   A0A151I5A6   A0A158NWV5   A0A195EDG7   A0A151IHN3   A0A151WYJ8   D6WK99   A0A0J7KG38   A0A182WAV5   A0A026W009   A0A1Q3G0Q7   A0A182LSA7   E9IVZ1   A0A084W1A8   W5JAR5   A0A182R2V6   A0A182YI78   A0A182URZ4   A0A182T4Q7   Q7Q2L7   A0A182KDH8   A0A182HGK5   A0A1B0CTT9   A0A182XPR0   A0A182NN75   A0A182QDT8   A0A182PMR1   A0A2M4BLR3   A0A067R2P3   U5ERT2   Q16PD3   A0A1B0D755   A0A2J7Q781   A0A2J7Q787   A0A347ZJ78   A0A1B6IJ58   A0A1B6DE16   A0A0K8UYE9   A0A1A9X8S0   A0A1B0BQQ2   A0A1A9ZK20   W8CD67   A0A1B0GA08   A0A034WMN8   E0W3Q2   A0A0A1WMX7   A0A1B6IKC3   A0A1A9WT15   A0A0L0CLE4   A0A2J7Q786   A0A1I8MLI0   A0A1I8NXS9   J9K8F3   A0A2S2PX77   A0A182TF02   A0A1W7R534   B4L1T5   W8BRV4   A0A0M8ZVV9   A0A0M5J7Z7   T1PAS0   B4NE15   B4GW83   A0A3B0JZI2   Q29IC4   B4JL68   B4PWV0   M9MS35   Q9W352   A0A0L7R0P5   B3NT84   B4R732   A0A1W4VUC8   A0A2R7WVS1   B3MZS1   A0A146M154   V4B1Y3  

PDB

4L7X     E-value=2.10067e-08,     Score=141

KEGG

101742619    K14960 COMPASS component SPP1 | (RefSeq) CXXC-type zinc finger protein 1-like

GO

GO:0003824   GO:0008270   GO:0045322   GO:0048188   GO:0009072   GO:0005737   GO:0046872   GO:0042302   GO:0016021   GO:0045893   GO:0051568   GO:0003677   GO:0005515   GO:0006357   GO:0006814   GO:0006270   GO:0042555   GO:0015930  

PANTHER

PTHR46174  

Subcellular location

Nucleus  

Length:

496

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01897

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01471

outside

1  -  496

 

 

Pi

260.952601

Theta

225.867969

Tajima's D

0.923223

CLR

0.741818

CSRT

0.637518124093795

Interpretation

Uncertain