Gene

KWMTBOMO15309

Pre Gene Modal

BGIBMGA005055

Annotation

PREDICTED:_putative_helicase_Mov10l1_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr25(+):8770287-8795236      View in EpiBrowser

Full name

Putative helicase mov-10-B.1       + More
Putative helicase mov-10-B.2      

Location in the cell

Nuclear   Reliability : 1.658 PlasmaMembrane   Reliability : 1.121

CDS

ATGAATTGCCAGTTGTGTTCTGAAAGCAATGTACCTTCTGATCATCACACTACTGAGAGACATATGAAAAATAAGACTTTGTTTGATTACTCTGTATACAAAAAACAGAATGTTGGAAATAAGAAGGGTATCATTGTATCATGTGATGTTAGATCTTCAAGCTCCACACATTCTCAGTGTTATGAGTCAAAAATAAATGTTTCTGTTAAGCCAAATGAACAAGTAGAGTTCACTTTCACAATCTTAAATGACACCAAGAAGGACAAATTTTCAATCAATTGTGCTCAAATAATGCATTCCAAATTAAACTTTACTATCAATGATCACGGAATTGATGCAGGCTCTCCACCACACATCATCAAGCCCAAATCGAAGCTCAACAAGAAAATTACAGTGATGTTCAGATCAGCGAGCGTTGGAGAATATGTGATGCCAATAGTATTCTGTTTTATTATGAACAGTACAAATGAAAACATTGTTATCGTTAGGGACATGGTCGTTTACGTTGAAAAACAGAAAAAGCTTCACGACAAAATGTACAGTCCTTTTGTACTTCAAAGTATTGTGGCAGAAAAGACATACAGATGCGTCCGTGAGGGGACAAGAGAAGAGGGTATATTCACAGTGCCAAAGAATTACAAGCCTATTTACAGTTCCGCGTTAAAGTGCCCCTCTAATCTCACTCAAGAAAAAGCAAAGCTGGTGGCAGATTTAAGGAAAATTTTCAGTACTGGCATCACCAAAATGAACTATGTTCAGTTTTTTCATCATCTGCTCTGGTACGAAGAAACTGTCCTCAAGAATAATCTAAAGAATTACAACATGACAGGCGTGAATCTAAAGCTCGGTAGCATTCCATCGTCGTACACGTTGGTCGTGCCCGGCTTAGCGGAGAAAAGACCGTCGTTGTTGGTTGGTGATTATTTGTTCGTTAAACCGCAAAATGAGAAGATAATGTTCGAAGCGAACGTCACTCTAATAACCGAGAATGACGTCACTATACAAGGCATGCATTCAACCTTTTTTAAGAACTACTCTAAAACTAAGAAGTACGACATACGGTTCACGATGTCCCGCGTGACCTTGGAACGGATGCACCAGGCGGTACACTTCGCCGAACAACAGATGCCCAGATTGTTCCCTACGCACTATACAAATAAGAAGAAAGTAGAACCAATAACGGAATTTTTTAACGTGAACATCCGAGACAACTTGGAGCAGCGCTCAGCCGTGGAGCACATCGTGTCGGGCAGCAGCGGGCGCGCGCCCTACCTCGTGCACGGGCCGCCCGGCACCGGCAAGACCGTCACCATCGTCGAAGCCATCCTGCAGCTTGTGGTGCGGAACTCTAAAAATCGAATACTTGTCTGCACCGACTCCAACATGGCGGCGGATAACGTGGCCACGATGCTTATAAAGTACGCCAAAAAGTTTCCTTCCGAAAAGTTTCTTTTAAGAGCGAGCTCCTTTTATCGAACATGGGCAACACTACCAGAATGCTTACATGCCTTTTCGAACGGTACAAGTACCAAAGACTTTTGGTCTGTGAGTTTCACAGTTTTCCAGAAATACGCGATCGTCATTACAACGTTATCGCACGCCGCCAAATTCAGCGGAAGTTTTAGTAAGAATAGCACGTGCCACATAACGCATCTGTTCATCGACGAAGCGGCCCAGGCTTCCGAGCCTGCCAGTCTCATCCCGATCTGCGGGCTGTTGTCTACCGCTGGTTCCCTGGTACTGGCCGGGGATCCCCTGCAACTGGGACCTGTCATCATTTCACAAAAGGCCAAAGAAATTGGCCTCGGTCTATCGCTCATGGAACGTTTGATGAAAACGTTTCCTCAGTACAACGACGTGAAGAACGACTGCAACTATATAATGCTGCTGCGCAATAACTTCAGATCTGATCCGGACATACTGCACATCCCTAACGAGTTGTTCTACAAGGGACAGCTCAGAGCTCATGCTAGTGAAGATCCGATAAGCAAGACCGATTTATCCGGCGAGAAACCATCCAGTCGCGCTATTATGTTCCACGGGGTCCTGTCTAAGGAACAGAAAGTTGGCATGTCACCGAGCTTCTACAATAACTCTGAGTTAGAAATCGTCCAGATGTACATAACGTTTCTCGTGAACGATCATAGAATCCAACTGGAAGATATCGGCGTCATCACTCCGTACATCCGACAAGCCTATCACATCAAGAAATGGCTCTCGAGCAATAATTACGAAAAAATTGAAGTCGGCACAGTCGAGTCGTTCCAAGGGAAGGAAAAGCGCGTCATCGTCGTGTCCACGGTTCGAGCCAACAACGACCTCCTCGCGCACGACGCCAAGTTCCAGCTCGGCTTCCTGGTTGATGATAAGCGTTTCAATGTGGCGCTGACACGTGCGAAAGCCAAACTTATCATTATTGGCAACCCCTTGTGTCTCCGGAAGGACAAGAAGTGGCAACTCTACATGCAGATGTGCCGCGAACTTGGCACCTATTTTGGTTTTGACAGTGACAACATTGAAACCGACGAACTGGACCGAAAGGTCGATGAGATCCTGCCGCTTTTCAGACACATTGAGGTTTCAAAACAAGAATAG

Protein

MNCQLCSESNVPSDHHTTERHMKNKTLFDYSVYKKQNVGNKKGIIVSCDVRSSSSTHSQCYESKINVSVKPNEQVEFTFTILNDTKKDKFSINCAQIMHSKLNFTINDHGIDAGSPPHIIKPKSKLNKKITVMFRSASVGEYVMPIVFCFIMNSTNENIVIVRDMVVYVEKQKKLHDKMYSPFVLQSIVAEKTYRCVREGTREEGIFTVPKNYKPIYSSALKCPSNLTQEKAKLVADLRKIFSTGITKMNYVQFFHHLLWYEETVLKNNLKNYNMTGVNLKLGSIPSSYTLVVPGLAEKRPSLLVGDYLFVKPQNEKIMFEANVTLITENDVTIQGMHSTFFKNYSKTKKYDIRFTMSRVTLERMHQAVHFAEQQMPRLFPTHYTNKKKVEPITEFFNVNIRDNLEQRSAVEHIVSGSSGRAPYLVHGPPGTGKTVTIVEAILQLVVRNSKNRILVCTDSNMAADNVATMLIKYAKKFPSEKFLLRASSFYRTWATLPECLHAFSNGTSTKDFWSVSFTVFQKYAIVITTLSHAAKFSGSFSKNSTCHITHLFIDEAAQASEPASLIPICGLLSTAGSLVLAGDPLQLGPVIISQKAKEIGLGLSLMERLMKTFPQYNDVKNDCNYIMLLRNNFRSDPDILHIPNELFYKGQLRAHASEDPISKTDLSGEKPSSRAIMFHGVLSKEQKVGMSPSFYNNSELEIVQMYITFLVNDHRIQLEDIGVITPYIRQAYHIKKWLSSNNYEKIEVGTVESFQGKEKRVIVVSTVRANNDLLAHDAKFQLGFLVDDKRFNVALTRAKAKLIIIGNPLCLRKDKKWQLYMQMCRELGTYFGFDSDNIETDELDRKVDEILPLFRHIEVSKQE

Description

Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC (By similarity).

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Similarity

Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.

Keywords

ATP-binding   Complete proteome   Cytoplasm   Helicase   Hydrolase   Nucleotide-binding   Reference proteome   RNA-binding   RNA-mediated gene silencing  

Feature

chain  Putative helicase mov-10-B.1

Uniprot

A0A2H1VG04   A0A2A4JW82   A0A2W1BH77   A0A194PMS1   A0A194RL89   A0A3S2NN90   + More
A0A212F8Y4   A0A1Y1LYA7   A0A2J7RK32   A0A1Y1LUS6   D6WC75   A0A2P8XCY3   V5GVH9   V5GJG8   A0A067RGC4   A0A1S3JER6   C3YAE9   Q1LXK4   A0A3P9P4N1   A0A3B3YTV1   A0A3B3XJF3   E7FAV9   A0A3Q2QVI1   A0A210QWW2   T1IYZ0   A0A146WTF8   A0A3B5PS47   A0A3P9P524   A0A3B3Z2B2   A0A146NPF4   A0A147BNX8   A0A131Y1W2   A0A3Q0S277   A0A3B3V1Y8   A0A3B3UZQ6   A0A2R8QPU7   A0A3B3UZP7   A0A3B3Q6V6   A0A3B3VLH2   A0A2R5LCG3   A0A3B4DPV0   A0A2G8LF59   A0A3B3ZT81   A0A067QX16   A0A087X566   A0A2I4B8M6   A0A371D0W8   A0A1W4ZBZ1   A0A3Q2U397   I3K2W3   M3ZF91   A0A146P8M9   A0A3B3C6G2   A0A1A8PTL8   A0A1Z5L1L7   A0A3P9Q782   A0A0C5XIN6   A0A3P9DQ48   A0A0P7UK81   A0A3P9KYN0   A0A1A8V552   I3K2W4   A0A1A8BHP7   A0A3P8RR32   A0A3B4GH31   A0A3Q4I2S6   A0A3P8VNH1   A0A3P8P1Y6   A0A3P9ILM6   A0A2G8JWJ6   A0A096M4W4   A0A1A8LBT4   A0A1A8NEX2   A0A3Q3ATU1   H2VC76   G1KUK0   K1QA54   A0A1A7YE69   A0A2I4C0Y2   A0A1W2W4F1   A0A3Q3LVL9   A0A1A7WDM5   A0A3B5BEL0   A0A3P9KB63   A0A1A8UTU0   A0A1A8EIU2   A0A1A8FFE9   A0A3Q2FDY9   W5MW54   T1IMR9   A0A3Q1G8A4   A0A3M6UH79   Q1LXK5   A0A3Q2DM66  

EC Number

3.6.4.13

Pubmed

28756777    26354079    22118469    28004739    18362917    19820115    + More
29403074    24845553    18563158    23594743    28812685    23542700    29652888    29240929    29023486    25463417    30061923    25186727    29451363    28528879    25724627    17554307    24487278    21551351    22992520    30382153   

EMBL

ODYU01002367    SOQ39778.1    NWSH01000562    PCG75642.1    KZ150095    PZC73621.1    + More
KQ459604    KPI92420.1    KQ460045    KPJ18085.1    RSAL01000001    RVE55283.1    AGBW02009658    OWR50204.1    GEZM01046296    JAV77350.1    NEVH01002981    PNF41192.1    GEZM01046297    JAV77349.1    KQ971316    EEZ97839.2    PYGN01002902    PSN29852.1    GALX01004228    JAB64238.1    GALX01004227    JAB64239.1    KK852657    KDR19239.1    GG666494    EEN62697.1    BX323059    BC171375    CU469362    NEDP02001463    OWF53196.1    JH431701    GCES01053125    JAR33198.1    GCES01152608    JAQ33714.1    GEGO01002951    JAR92453.1    GEFM01002313    JAP73483.1    BX248319    GGLE01003019    MBY07145.1    MRZV01000101    PIK58790.1    KK852866    KDR14736.1    AYCK01012747    KZ857430    RDX46173.1    AERX01019455    AERX01019456    AERX01019457    GCES01146592    JAQ39730.1    HAEI01003374    SBR84329.1    GFJQ02005687    JAW01283.1    KP128064    AJR21491.1    JARO02009229    KPP61866.1    HADY01017972    HAEJ01015033    SBS55490.1    HADZ01002235    SBP66176.1    MRZV01001162    PIK40113.1    HAEF01004576    SBR41958.1    HAEH01001676    SBR67377.1    JH818778    EKC30838.1    HADX01006207    SBP28439.1    HADW01002513    SBP03913.1    HADY01012439    HAEJ01011033    SBS51490.1    HAEB01000573    SBQ47025.1    HAEB01011225    SBQ57752.1    AHAT01014313    JH431094    RCHS01001556    RMX52929.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000283053    UP000007151    UP000235965    + More
UP000007266    UP000245037    UP000027135    UP000085678    UP000001554    UP000000437    UP000242638    UP000261480    UP000265000    UP000242188    UP000002852    UP000261340    UP000261500    UP000261540    UP000261440    UP000230750    UP000261520    UP000028760    UP000192220    UP000256964    UP000192224    UP000005207    UP000261560    UP000265160    UP000034805    UP000265180    UP000265080    UP000261460    UP000261580    UP000265120    UP000265100    UP000265200    UP000264800    UP000005226    UP000001646    UP000005408    UP000261660    UP000261400    UP000265020    UP000018468    UP000257200    UP000275408   

PRIDE

Q1LXK4    Q1LXK5   

Pfam

PF13087   AAA_12        + More
PF13086   AAA_11

Interpro

IPR041677   DNA2/NAM7_AAA_11        + More
IPR027417   P-loop_NTPase       
IPR026122   MOV-10       
IPR041679   DNA2/NAM7-like_AAA       
IPR014001   Helicase_ATP-bd       
IPR003593   AAA+_ATPase       
IPR036236   Znf_C2H2_sf       
IPR013087   Znf_C2H2_type       
IPR003604   Matrin/U1-like-C_Znf_C2H2       

SUPFAM

SSF52540   SSF52540        + More
SSF57667   SSF57667       

ProteinModelPortal

A0A2H1VG04   A0A2A4JW82   A0A2W1BH77   A0A194PMS1   A0A194RL89   A0A3S2NN90   + More
A0A212F8Y4   A0A1Y1LYA7   A0A2J7RK32   A0A1Y1LUS6   D6WC75   A0A2P8XCY3   V5GVH9   V5GJG8   A0A067RGC4   A0A1S3JER6   C3YAE9   Q1LXK4   A0A3P9P4N1   A0A3B3YTV1   A0A3B3XJF3   E7FAV9   A0A3Q2QVI1   A0A210QWW2   T1IYZ0   A0A146WTF8   A0A3B5PS47   A0A3P9P524   A0A3B3Z2B2   A0A146NPF4   A0A147BNX8   A0A131Y1W2   A0A3Q0S277   A0A3B3V1Y8   A0A3B3UZQ6   A0A2R8QPU7   A0A3B3UZP7   A0A3B3Q6V6   A0A3B3VLH2   A0A2R5LCG3   A0A3B4DPV0   A0A2G8LF59   A0A3B3ZT81   A0A067QX16   A0A087X566   A0A2I4B8M6   A0A371D0W8   A0A1W4ZBZ1   A0A3Q2U397   I3K2W3   M3ZF91   A0A146P8M9   A0A3B3C6G2   A0A1A8PTL8   A0A1Z5L1L7   A0A3P9Q782   A0A0C5XIN6   A0A3P9DQ48   A0A0P7UK81   A0A3P9KYN0   A0A1A8V552   I3K2W4   A0A1A8BHP7   A0A3P8RR32   A0A3B4GH31   A0A3Q4I2S6   A0A3P8VNH1   A0A3P8P1Y6   A0A3P9ILM6   A0A2G8JWJ6   A0A096M4W4   A0A1A8LBT4   A0A1A8NEX2   A0A3Q3ATU1   H2VC76   G1KUK0   K1QA54   A0A1A7YE69   A0A2I4C0Y2   A0A1W2W4F1   A0A3Q3LVL9   A0A1A7WDM5   A0A3B5BEL0   A0A3P9KB63   A0A1A8UTU0   A0A1A8EIU2   A0A1A8FFE9   A0A3Q2FDY9   W5MW54   T1IMR9   A0A3Q1G8A4   A0A3M6UH79   Q1LXK5   A0A3Q2DM66  

PDB

2WJY     E-value=1.00296e-36,     Score=388

KEGG

101744685    K18422 helicase MOV-10 [EC:3.6.4.13] | (RefSeq) putative helicase Mov10l1

GO

GO:0032575   GO:0035194   GO:0003723   GO:0043186   GO:0005829   GO:0005524   GO:0035279   GO:0000932   GO:0016021   GO:0008270   GO:0061158   GO:0010526  

PANTHER

PTHR10887:SF419  

Subcellular location

  

Length:

864

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.67425

Exp number, first 60 AAs:

0

Total prob of N-in:

0.07530

outside

1  -  864

 

 

Pi

338.013445

Theta

190.189247

Tajima's D

1.288007

CLR

0.619495

CSRT

0.738613069346533

Interpretation

Uncertain