Gene

KWMTBOMO15291

Pre Gene Modal

BGIBMGA005152

Annotation

PREDICTED:_N-alpha-acetyltransferase_40-like_[Plutella_xylostella]

Location

Bomo_Chr25(-):8468095-8469722      View in EpiBrowser

Full name

N-alpha-acetyltransferase 40      

Alternative Name

N-acetyltransferase 11
N-alpha-acetyltransferase D

Location in the cell

Cytoplasmic   Reliability : 1.964

CDS

ATGGGAAAAAAATCAATAACAGCTACAAACAAACAGAAAGATAAGCGGCTTGCTAGAAAGCAAGAACAGAGGCGCATTGCTGATGCTATGACCCACGTTACAACTGCAAATAAACTTCAAGACTTGGCATCCTTGTGCAAAGAATTGTTAGTTTTCCGTAATCTCGACCTGGAGGTAGACATGTATATACAAAAGGTCACTGAACTGGATAAAAAGGTGTTACAGTGGGCCATAGACTTGACTGAAAAAAATATGAAGACACTCTATGAAACTTGTGCATGGGGTTGGAATCCTAATCGTAAGCTGGAGGAAATGACTGATGATGCAGCCTGGTATCTGATAGCCCGTGAGAAAAATGGAACACTCCTAGCTTTCTCACACTTCAGATTTGACCTGGACTTTGGAGAACCAGTATTGTATTGGTAA

Protein

MGKKSITATNKQKDKRLARKQEQRRIADAMTHVTTANKLQDLASLCKELLVFRNLDLEVDMYIQKVTELDKKVLQWAIDLTEKNMKTLYETCAWGWNPNRKLEEMTDDAAWYLIAREKNGTLLAFSHFRFDLDFGEPVLYW

Description

N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A. In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence'.

Catalytic Activity

acetyl-CoA + N-terminal L-seryl-[histone H4] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[histone H4]
acetyl-CoA + N-terminal L-seryl-[histone H2A] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[histone H2A]

Similarity

Belongs to the acetyltransferase family. NAA40 subfamily.

Keywords

Acyltransferase   Complete proteome   Cytoplasm   Lipoprotein   Myristate   Nucleus   Reference proteome   Transferase  

Feature

chain  N-alpha-acetyltransferase 40

Uniprot

H9J6L0   A0A2H1W400   A0A2A4IXI7   A0A212F8V5   A0A194PGH2   S4PDK5   + More
A0A0L7LVG0   A0A2W1BRS2   A0A194RKN7   A0A0T6B9J1   D6WTU5   A0A1Y1LHG7   N6TUE7   A0A2P8ZEI7   A0A1W4X8Y2   A0A1B6E3A6   A0A1S3J8M6   A0A0S7KNX7   R4V491   R4V3V0   E7EYF8   A0A3Q1D0E5   A0A3P9MUY8   A0A3B3WZN0   A0A087X6M3   A0A3B3VI12   A0A3Q2DZF4   A0A0A9ZD19   A0A0S7KNY5   A0A146Z5U4   A0A146NIG4   A0A2J7Q5I5   A0A2G9RV71   H3AVZ7   A0A146NVT9   A0A3Q2SVT0   A0A0A0A321   Q568K5   A0A3Q0QP70   H2SHB1   F6Q9B3   A0A2D4IQR2   A0A3B4GSV5   A0A3Q2WX80   A0A3P8QP87   A0A3P9B3H2   A0A3Q3ADL3   H9GIW2   A0A1A7YZE9   A0A1A8CJ69   A0A1L8GJR5   Q6NUH2   A0A1A8K9P1   A0A1A8GRI1   A0A1A8UQ09   A0A1S2ZFJ1   A0A1A8RT88   A0A1A8MR23   A0A2K5E9L4   A0A1D5P6G2   D3ZZQ5   M4ARI7   F6TZV6   A0A315VUX3   A0A2I4C3D1   Q5R9Y8   A0A067RJN6   B1H2T3   A0A3Q1FJ56   A0A3B5AZ00   A0A3P8WFH8   A0A091MH54   A0A3B4YSS0   A0A3B4VGJ7   A0A0P4WKD8   A0A3Q7R2G9   M3WL36   A0A2Y9JU26   A0A3Q7SH25   A0A2U3VH14   M3YPG1   A0A3Q7UG47   A0A224XNP9   A0A0D9R3I5   A0A1S3D588   H3D8J1   A0A2U4B4P0   A0A2Y9PNV1   A0A2I2Y7F3   A0A2Y9EIG7   Q4S0U7   A0A3Q7SWT3   I3MH75   A0A2K6C2Z0   L5KQC7   A0A2K5U6T7   A0A2K5K7P8   A0A2K6FV15   H9FZX2  

EC Number

2.3.1.257

Pubmed

19121390    22118469    26354079    23622113    26227816    28756777    + More
18362917    19820115    28004739    23537049    29403074    23594743    25401762    26823975    9215903    21551351    17495919    25186727    21881562    27762356    15592404    15057822    15632090    23542700    25243066    29703783    24845553    20431018    24487278    17975172    15496914    22398555    23258410    25319552   

EMBL

BABH01019867    ODYU01006049    SOQ47562.1    NWSH01005189    PCG64369.1    AGBW02009658    + More
OWR50185.1    KQ459604    KPI92402.1    GAIX01003641    JAA88919.1    JTDY01000014    KOB79420.1    KZ149994    PZC75480.1    KQ460045    KPJ18102.1    LJIG01003015    KRT83925.1    KQ971352    EFA07325.1    GEZM01055207    JAV73089.1    APGK01018323    APGK01018324    APGK01018325    KB740073    KB632222    ENN81673.1    ERL90203.1    PYGN01000079    PSN54922.1    GEDC01004894    JAS32404.1    GBYX01202420    GBYX01202419    JAO79047.1    KC740844    AGM32668.1    KC571989    AGM32488.1    CABZ01043953    AYCK01016166    GBHO01002366    GBRD01018121    GDHC01002865    JAG41238.1    JAG47706.1    JAQ15764.1    GBYX01202423    GBYX01202422    JAO79045.1    GCES01025256    JAR61067.1    GCES01155067    JAQ31255.1    NEVH01017557    PNF23835.1    KV929863    PIO31113.1    AFYH01015748    GCES01150448    JAQ35874.1    KL870439    KGL88446.1    BC092819    IACK01118948    LAA86591.1    AAWZ02032030    HADW01001147    HADX01013264    SBP35496.1    HADZ01014865    HAEA01005438    SBP78806.1    CM004472    OCT84087.1    BC068615    HAED01002534    HAEE01008871    SBR28921.1    HAEB01021349    HAEC01005690    SBQ73767.1    HADY01013365    HAEJ01008960    SBS49417.1    HAEI01009692    SBS08484.1    HAEF01017862    HAEG01015413    SBR59021.1    AADN05000754    AC126148    CH473953    EDM12671.1    GAMT01001998    GAMS01005015    GAMR01009740    GAMQ01005392    GAMP01010297    JAB09863.1    JAB18121.1    JAB24192.1    JAB36459.1    JAB42458.1    NHOQ01001086    PWA27160.1    CR859242    CAH91422.1    KK852428    KDR24066.1    AAMC01118463    BC161120    AAI61120.1    KK504630    KFP60915.1    GDRN01083168    JAI61709.1    AANG04000779    AEYP01074286    AEYP01074287    AEYP01074288    GFTR01003712    JAW12714.1    AQIB01078872    AQIB01078873    AQIB01078874    AQIB01078875    CABD030079646    CABD030079647    CABD030079648    CABD030079649    CAAE01014779    CAG05735.1    AGTP01072483    AGTP01072484    KB030625    ELK13410.1    AQIA01019940    AQIA01019941    AQIA01019942    JU336428    JU477242    JU477243    JU477244    JU477245    JV048279    AFE80181.1    AFH34046.1    AFI38350.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000037510    UP000053240    + More
UP000007266    UP000019118    UP000030742    UP000245037    UP000192223    UP000085678    UP000000437    UP000257160    UP000242638    UP000261480    UP000028760    UP000261500    UP000265020    UP000265000    UP000235965    UP000008672    UP000053858    UP000261340    UP000005226    UP000002280    UP000261460    UP000264840    UP000265100    UP000265160    UP000264800    UP000001646    UP000186698    UP000079721    UP000233020    UP000000539    UP000002494    UP000002852    UP000008225    UP000192220    UP000027135    UP000008143    UP000257200    UP000261400    UP000265120    UP000261360    UP000261420    UP000286641    UP000011712    UP000248482    UP000286640    UP000245340    UP000000715    UP000286642    UP000029965    UP000079169    UP000007303    UP000245320    UP000248483    UP000001519    UP000248484    UP000005215    UP000233120    UP000010552    UP000233100    UP000233080    UP000233160   

PRIDE

H9J6L0    D3ZZQ5   

Pfam

PF00583   Acetyltransf_1

Interpro

IPR039949   NAA40        + More
IPR016181   Acyl_CoA_acyltransferase       
IPR000182   GNAT_dom       

SUPFAM

SSF55729   SSF55729       

ProteinModelPortal

H9J6L0   A0A2H1W400   A0A2A4IXI7   A0A212F8V5   A0A194PGH2   S4PDK5   + More
A0A0L7LVG0   A0A2W1BRS2   A0A194RKN7   A0A0T6B9J1   D6WTU5   A0A1Y1LHG7   N6TUE7   A0A2P8ZEI7   A0A1W4X8Y2   A0A1B6E3A6   A0A1S3J8M6   A0A0S7KNX7   R4V491   R4V3V0   E7EYF8   A0A3Q1D0E5   A0A3P9MUY8   A0A3B3WZN0   A0A087X6M3   A0A3B3VI12   A0A3Q2DZF4   A0A0A9ZD19   A0A0S7KNY5   A0A146Z5U4   A0A146NIG4   A0A2J7Q5I5   A0A2G9RV71   H3AVZ7   A0A146NVT9   A0A3Q2SVT0   A0A0A0A321   Q568K5   A0A3Q0QP70   H2SHB1   F6Q9B3   A0A2D4IQR2   A0A3B4GSV5   A0A3Q2WX80   A0A3P8QP87   A0A3P9B3H2   A0A3Q3ADL3   H9GIW2   A0A1A7YZE9   A0A1A8CJ69   A0A1L8GJR5   Q6NUH2   A0A1A8K9P1   A0A1A8GRI1   A0A1A8UQ09   A0A1S2ZFJ1   A0A1A8RT88   A0A1A8MR23   A0A2K5E9L4   A0A1D5P6G2   D3ZZQ5   M4ARI7   F6TZV6   A0A315VUX3   A0A2I4C3D1   Q5R9Y8   A0A067RJN6   B1H2T3   A0A3Q1FJ56   A0A3B5AZ00   A0A3P8WFH8   A0A091MH54   A0A3B4YSS0   A0A3B4VGJ7   A0A0P4WKD8   A0A3Q7R2G9   M3WL36   A0A2Y9JU26   A0A3Q7SH25   A0A2U3VH14   M3YPG1   A0A3Q7UG47   A0A224XNP9   A0A0D9R3I5   A0A1S3D588   H3D8J1   A0A2U4B4P0   A0A2Y9PNV1   A0A2I2Y7F3   A0A2Y9EIG7   Q4S0U7   A0A3Q7SWT3   I3MH75   A0A2K6C2Z0   L5KQC7   A0A2K5U6T7   A0A2K5K7P8   A0A2K6FV15   H9FZX2  

PDB

4U9W     E-value=5.99226e-21,     Score=242

KEGG

101746457    K20794 N-alpha-acetyltransferase 40 [EC:2.3.1.257] | (RefSeq) N-alpha-acetyltransferase 40

GO

GO:0043998   GO:0010485   GO:0061187   GO:0006474   GO:1990189   GO:0043968   GO:0005634   GO:0005737   GO:0043967   GO:0006629   GO:0016740  

PANTHER

PTHR20531  

Subcellular location

Cytoplasm  
Nucleus  

Length:

141

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00706

Exp number, first 60 AAs:

0.00012

Total prob of N-in:

0.44189

outside

1  -  141

 

 

Pi

260.378495

Theta

187.37093

Tajima's D

1.074208

CLR

0.016194

CSRT

0.67691615419229

Interpretation

Uncertain