Gene

KWMTBOMO15259

Annotation

PREDICTED:_phosphatidylinositol_N-acetylglucosaminyltransferase_subunit_H_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr25(+):7621546-7624420      View in EpiBrowser

Full name

Phosphatidylinositol N-acetylglucosaminyltransferase subunit H      

Alternative Name

Phosphatidylinositol-glycan biosynthesis class H protein

Location in the cell

Nuclear   Reliability : 0.865

CDS

ATGCTAAAATCAGAAACAGTCTTGATCGTTCCAAATGTTGGTATACGCAGCACTCAGAATTATCCAACCAGAAACTTACACACCTTTGTATCATGGGACAGAATTGAAGATATTATTATAAATGAAGTTATTGTGACGTCTAAAGTTCTTTATTACTTGACTATTTTGGTTAAAGAAGATCCTGAGAACACTGGAAACATTGAACAAAATCAATCAACCCGACTGGTGCCTCTTTTTTTGAGGACAAGACCCAGTTTGGCGGTGTTGGAGAAGATTTATGCAGATGTACAAGACTTACTGACGGAGGCTAAGCAACAAGTGTAA

Protein

MLKSETVLIVPNVGIRSTQNYPTRNLHTFVSWDRIEDIIINEVIVTSKVLYYLTILVKEDPENTGNIEQNQSTRLVPLFLRTRPSLAVLEKIYADVQDLLTEAKQQV

Description

Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

Catalytic Activity

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(+) + UDP

Subunit

Associates with PIGA, PIGC, PIGP, PIGQ and DPM2. The latter is not essential for activity (By similarity).

Similarity

Belongs to the PIGH family.

Keywords

Complete proteome   Cytoplasm   Glycosyltransferase   Reference proteome   Transferase  

Feature

chain  Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

Uniprot

A0A1E1VZA3   A0A194PGE1   A0A2H1WE54   A0A3S2NSN5   A0A2W1BLG0   A0A194RJX1   + More
A0A2A4JA89   A0A212F711   A0A1A8M804   A0A1A8H187   A0A1A8CGW3   A0A1A8NBV4   A0A1A8U1K9   A0A1A8K412   A0A3Q1GBW4   A0A3B3QDI2   A0A3B4U5H9   A0A1A8S3R1   A0A1A7YIC8   H0XE05   A0A3B4W8V9   A0A3B3VBK0   A0A0S7LNY9   A0A3Q1B238   A0A3P8UA51   A0A3B5LQU0   A0A3B3Z0T3   M3ZX75   A0A087Y4H5   A0A3Q3M5P4   A0A2U9CT63   A0A096LUA4   A0A1A8IPH1   A0A315VWX9   I3IWG8   A0A3B4ZW30   A0A1U7QQY2   Q5M9N4   A0A0P4WBV5   A0A3Q2XN48   A0A2K5JTX7   W5N3H0   G3H1L9   A0A3B4F0N6   A0A3Q4I5K8   A0A3Q2W6A7   A0A3P8NYI5   A0A3P9C576   A0A3Q3K2V3   A0A3Q3B943   H0V0L7   A0A3B5K8G5   R0LCM1   A0A1A6G0X7   U3HZL7   D2HRG4   A0A212CTC5   A0A3Q3NDK9   A0A2Y9MYL5   A0A2Y9N9T7   A0A146ZN65   G5C7X7   S9WMG6   A0A2Y9N3L7   C1BXY9   A0A2U3V0Q8   A0A341BJW0   U6CTX9   M3Y6V1   L5M1N3   A0A2U4A9Y5   D4A0Z0   A0A3P9PE53   A0A3P9PE38   A0A2R8MDP4   A0A2Y9FFY8   A0A287A3K3   A0A2Y9DB08   A0A2R8PH55   A0A0E9X8D9   A0A3P9AH83   A0A3Q0QS54   A0A3P4LSH1   A0A2K5EK16   A0A091CZR3   U3CIG1   W5QJ53   A0A096NVP3   G8F4W5   F6URF9   A0A3P8YXB1   A0A2K5S1L1   F1MGP1   A0A2K6S5P0   A0A3L7HKN0   L8HYV5   A0A384AAP4   Q32L89   A0A0P5EBK7   A0A3Q7W581  

EC Number

2.4.1.198

Pubmed

26354079    28756777    22118469    29240929    23542700    29703783    + More
25186727    16141072    15489334    21804562    21993624    21551351    23749191    20010809    21993625    23149746    20433749    15057822    15632090    30723633    25613341    25069045    25243066    20809919    22002653    17431167    19393038    29704459    22751099   

EMBL

GDQN01010994    JAT80060.1    KQ459604    KPI92372.1    ODYU01008067    SOQ51349.1    + More
RSAL01000001    RVE55343.1    KZ150046    PZC74495.1    KQ460045    KPJ18128.1    NWSH01002167    PCG69005.1    AGBW02009942    OWR49532.1    HAEF01011798    SBR52957.1    HAEB01009751    HAEC01009037    SBQ77253.1    HADZ01014367    HAEA01007840    SBP78308.1    HAEG01001976    SBR66334.1    HADY01011441    HAEJ01001503    SBS41960.1    HAEE01006937    SBR26957.1    HAEH01010132    HAEI01010994    SBS12174.1    HADW01018477    HADX01008105    SBP30337.1    AAQR03134929    GBYX01158480    JAO91174.1    AYCK01008713    CP026262    AWP19834.1    AWP19835.1    AWP19836.1    AWP19837.1    HAED01012781    SBQ99183.1    NHOQ01001000    PWA27820.1    AERX01005496    AK167892    BC086806    GDRN01075575    JAI63039.1    AHAT01019062    AHAT01019063    JH000107    EGV91866.1    AAKN02025210    AAKN02025211    KB743356    EOA99244.1    LZPO01107950    OBS59826.1    ADON01090394    ACTA01105694    ACTA01113694    GL193220    EFB27438.1    MKHE01000012    OWK09240.1    GCES01018533    JAR67790.1    JH173719    GEBF01003757    EHB17638.1    JAN99875.1    KB017142    EPY79727.1    BT079468    ACO13892.1    HAAF01002065    CCP73891.1    AEYP01004105    AEYP01004106    KB105175    ELK32554.1    AABR07064961    CH473947    EDM03717.1    AEMK02000061    DQIR01245654    DQIR01287508    HDC01132.1    HDC42986.1    GBXM01010457    JAH98120.1    CYRY02002172    VCW66832.1    KN123629    KFO24192.1    GAMT01007528    GAMS01004987    GAMR01002640    GAMQ01003428    JAB04333.1    JAB18149.1    JAB31292.1    JAB38423.1    AMGL01104303    AHZZ02032335    AQIA01065284    JH331132    EHH62329.1    JSUE03039944    JSUE03039945    CM001259    EHH27980.1    RAZU01000203    RLQ65891.1    JH882530    ELR49056.1    BC109701    GDIP01145304    JAJ78098.1   

Proteomes

UP000053268    UP000283053    UP000053240    UP000218220    UP000007151    UP000257200    + More
UP000261540    UP000261420    UP000005225    UP000261360    UP000261500    UP000257160    UP000265080    UP000261380    UP000261480    UP000002852    UP000028760    UP000261640    UP000246464    UP000005207    UP000261400    UP000189706    UP000000589    UP000264820    UP000233080    UP000018468    UP000001075    UP000261460    UP000261580    UP000264840    UP000265100    UP000265160    UP000261600    UP000264800    UP000005447    UP000005226    UP000092124    UP000016666    UP000008912    UP000261660    UP000248483    UP000006813    UP000245320    UP000252040    UP000000715    UP000002494    UP000242638    UP000008225    UP000248484    UP000008227    UP000248480    UP000265140    UP000261340    UP000233020    UP000028990    UP000002356    UP000028761    UP000009130    UP000233100    UP000006718    UP000233040    UP000009136    UP000233220    UP000273346    UP000261681    UP000286642   

PRIDE

Q5M9N4    G3H1L9   

Pfam

PF10181   PIG-H

Interpro

IPR019328   GPI-GlcNAc_Trfase_PIG-H_dom       

ProteinModelPortal

A0A1E1VZA3   A0A194PGE1   A0A2H1WE54   A0A3S2NSN5   A0A2W1BLG0   A0A194RJX1   + More
A0A2A4JA89   A0A212F711   A0A1A8M804   A0A1A8H187   A0A1A8CGW3   A0A1A8NBV4   A0A1A8U1K9   A0A1A8K412   A0A3Q1GBW4   A0A3B3QDI2   A0A3B4U5H9   A0A1A8S3R1   A0A1A7YIC8   H0XE05   A0A3B4W8V9   A0A3B3VBK0   A0A0S7LNY9   A0A3Q1B238   A0A3P8UA51   A0A3B5LQU0   A0A3B3Z0T3   M3ZX75   A0A087Y4H5   A0A3Q3M5P4   A0A2U9CT63   A0A096LUA4   A0A1A8IPH1   A0A315VWX9   I3IWG8   A0A3B4ZW30   A0A1U7QQY2   Q5M9N4   A0A0P4WBV5   A0A3Q2XN48   A0A2K5JTX7   W5N3H0   G3H1L9   A0A3B4F0N6   A0A3Q4I5K8   A0A3Q2W6A7   A0A3P8NYI5   A0A3P9C576   A0A3Q3K2V3   A0A3Q3B943   H0V0L7   A0A3B5K8G5   R0LCM1   A0A1A6G0X7   U3HZL7   D2HRG4   A0A212CTC5   A0A3Q3NDK9   A0A2Y9MYL5   A0A2Y9N9T7   A0A146ZN65   G5C7X7   S9WMG6   A0A2Y9N3L7   C1BXY9   A0A2U3V0Q8   A0A341BJW0   U6CTX9   M3Y6V1   L5M1N3   A0A2U4A9Y5   D4A0Z0   A0A3P9PE53   A0A3P9PE38   A0A2R8MDP4   A0A2Y9FFY8   A0A287A3K3   A0A2Y9DB08   A0A2R8PH55   A0A0E9X8D9   A0A3P9AH83   A0A3Q0QS54   A0A3P4LSH1   A0A2K5EK16   A0A091CZR3   U3CIG1   W5QJ53   A0A096NVP3   G8F4W5   F6URF9   A0A3P8YXB1   A0A2K5S1L1   F1MGP1   A0A2K6S5P0   A0A3L7HKN0   L8HYV5   A0A384AAP4   Q32L89   A0A0P5EBK7   A0A3Q7W581  

KEGG

101737895    K03858 phosphatidylinositol N-acetylglucosaminyltransferase subunit H | (RefSeq) phosphatidylinosito

PATHWAY

00563    Glycosylphosphatidylinositol (GPI)-anchor biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0017176   GO:0000506   GO:0006506   GO:0016757   GO:0046872   GO:0050660   GO:0050661   GO:0005524   GO:0016020   GO:0003677   GO:0008408   GO:0005112   GO:0015930  

Subcellular location

Cytoplasm  

Length:

107

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.14208

Exp number, first 60 AAs:

0.14208

Total prob of N-in:

0.13588

outside

1  -  107

 

 

Pi

251.701613

Theta

144.644394

Tajima's D

2.322303

CLR

0.101175

CSRT

0.926803659817009

Interpretation

Uncertain