Gene

KWMTBOMO15233

Pre Gene Modal

BGIBMGA005170

Annotation

transient_receptor_potential_channel_pyrexia_[Bombyx_mori]

Location

Bomo_Chr25(-):7180535-7184213      View in EpiBrowser

Full name

Transient receptor potential channel pyrexia      

Location in the cell

Cytoplasmic   Reliability : 3.063

CDS

ATGAGTCAATTGCCGGAGGATGTAGAGGATGATGTCGAAGGAGGATACATATCTAGCGACGAGTCAGCACACGGCGCTGATCTCGCTGAGCGTCTGAGGGTCAAACCTTCTAAAGATATATGGGAACTGGACGAGATACAGTACACGTTACGGCTACTGCCGTATTCAGAAGAAATATCAGTACTTATAGGTAATGGGAATTACGATGAAACAATACAGTTTGCCTCCGAGGCTGAAGGCGGATTTGGCCTACGAACAGCCATCCTTTGGGCCTGTTGGCTCGGAAAGAGTATTCTGCTTTTTAAATTGCTAAAAATGGGCGTTGATCCCGATGAACTAGACGATGCCGGAAGGACATGTTTACATTTAAGTTGTTTAGTTGGAAGCGAAGAATGCGTGAAGCTTCTACTCGACCACGGAGCGCACCCGAATACATGGGACTCGTCTACAGAAACAAAAGCGACGCCTCTCCATTGCGCAGCCAGCGCCAAAAGTTTAGCTTGCGTAAAGGTGTTGATCGCTCATGGTGCTGACGTAAATGCCGGTTTAAGTGACAGGTCTCCGTTACATTACGCCGTCCTCAGCGATGCACCGGAAGTTGTGAAGGAATTATTAGAAGCTGGTGCGTGCCCCGACACGCCACAGGTGGGCTGTCTAAATTCATTTCAAACACAAACCAGATACTAA

Protein

MSQLPEDVEDDVEGGYISSDESAHGADLAERLRVKPSKDIWELDEIQYTLRLLPYSEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVGCLNSFQTQTRY

Description

Receptor-activated non-selective cation channel involved in protection or tolerance from high temperature stress. Activated by temperatures above 40 degrees Celsius. More permeable to K(+) than to Na(+). May act in stress protection allow flies to survive in natural environments.

Subunit

Homooligomer; between isoform A and isoform B.

Similarity

Belongs to the transient receptor (TC 1.A.4) family.
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.

Keywords

Alternative splicing   ANK repeat   Complete proteome   Glycoprotein   Ion channel   Ion transport   Membrane   Reference proteome   Repeat   Sensory transduction   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Transient receptor potential channel pyrexia
splice variant  In isoform B.

Uniprot

H9J6M8   W8VMI8   A0A0L7K8K9   A0A3S2NSL9   A0A2W1BQK8   A0A2A4IZ93   + More
A0A2A4J0Z3   A0A2H1VL68   A0A194RQ48   A0A194PG37   A0A212FEW5   A0A1Y1LNQ8   A0A067QSF9   A0A2J7Q265   D6WP79   A0A2P8YP14   B0WV08   A0A182GUK9   W5JS40   A0A182FJL5   A0A182W409   A0A182JWI8   Q0IFQ4   A0A182YQW8   A0A182T252   A0A182MX57   A0A182R6D4   A0A182Q024   E0W076   A0A1W4WPQ0   A0A182HIK5   Q7QEQ9   A0A182UYH1   A0A182WY66   A0A1J1J7Z5   A0A1A9WB91   A0A182JF36   B3M8Z5   A0A182N044   A0A1B0BMT9   A0A0M4EKT2   A0A1A9XD69   A0A336M1Y6   A0A336MEW4   B4H5D3   Q29ER3   A0A336MAH4   A0A1B0A764   B4KKC1   A0A3B0JY03   A0A1B0FHA3   B4QKU8   B4HVD0   A0A0J9UBA1   B4LS35   A0A1I8NXE6   B3NEM1   A0A1I8NAZ6   Q9W0T5   A0A1A9UH95   B4PC33   W8BAK3   A0A0L0BVP7   W8BFJ6   B4JQN9   B4N427   A0A182PFC5   A0A0K2SXU5  

Pubmed

19121390    24639527    26227816    28756777    26354079    22118469    + More
28004739    24845553    18362917    19820115    29403074    26483478    20920257    23761445    17510324    25244985    20566863    12364791    14747013    17210077    17994087    15632085    22936249    18057021    25315136    10731132    12537572    12537569    15731759    17550304    24495485    26108605   

EMBL

BABH01019984    BABH01019985    AB437368    BAO53209.1    JTDY01010234    KOB59632.1    + More
RSAL01000102    RVE47475.1    KZ150014    PZC75020.1    NWSH01004460    PCG65081.1    PCG65082.1    ODYU01003165    SOQ41565.1    KQ460045    KPJ18146.1    KQ459604    KPI92351.1    AGBW02008891    OWR52289.1    GEZM01050962    GEZM01050961    JAV75259.1    KK853628    KDR03815.1    NEVH01019373    PNF22682.1    KQ971353    EFA07512.1    PYGN01000457    PSN45985.1    DS232115    EDS35336.1    JXUM01089330    JXUM01089331    KQ563763    KXJ73352.1    ADMH02000338    ETN66911.1    CH477294    EAT44480.1    AXCM01004049    AXCN02002023    AAZO01006645    DS235857    EEB19032.1    APCN01003993    AAAB01008846    EAA06365.5    CVRI01000069    CRL07025.1    CH902618    EDV38939.1    JXJN01017053    CP012525    ALC43922.1    UFQS01000411    UFQT01000411    SSX03695.1    SSX24060.1    UFQS01000805    UFQT01000805    SSX06999.1    SSX27343.1    CH479211    EDW32985.1    CH379070    EAL29997.2    SSX06998.1    SSX27342.1    CH933807    EDW12652.1    OUUW01000012    SPP86934.1    CCAG010019361    CM000363    EDX08694.1    CH480817    EDW49895.1    CM002912    KMY96600.1    CH940649    EDW64721.1    KRF81817.1    CH954178    EDV50016.1    AE014296    BT001363    BT010317    CM000159    EDW92688.1    GAMC01010838    JAB95717.1    JRES01001267    KNC24063.1    GAMC01010837    JAB95718.1    CH916372    EDV99219.1    CH964095    EDW78901.1    HACA01001213    CDW18574.1   

Proteomes

UP000005204    UP000037510    UP000283053    UP000218220    UP000053240    UP000053268    + More
UP000007151    UP000027135    UP000235965    UP000007266    UP000245037    UP000002320    UP000069940    UP000249989    UP000000673    UP000069272    UP000075920    UP000075881    UP000008820    UP000076408    UP000075901    UP000075883    UP000075900    UP000075886    UP000009046    UP000192223    UP000075840    UP000007062    UP000075903    UP000076407    UP000183832    UP000091820    UP000075880    UP000007801    UP000075884    UP000092460    UP000092553    UP000092443    UP000008744    UP000001819    UP000092445    UP000009192    UP000268350    UP000092444    UP000000304    UP000001292    UP000008792    UP000095300    UP000008711    UP000095301    UP000000803    UP000078200    UP000002282    UP000037069    UP000001070    UP000007798    UP000075885   

PRIDE

H9J6M8    W8VMI8    Q9W0T5   

Pfam

PF00023   Ank        + More
PF00520   Ion_trans
PF12796   Ank_2
PF13606   Ank_3

Interpro

IPR005821   Ion_trans_dom        + More
IPR020683   Ankyrin_rpt-contain_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR002110   Ankyrin_rpt       

SUPFAM

SSF48403   SSF48403       

Gene 3D

1.25.40.20    

CDD

cd00204  ANK

ProteinModelPortal

H9J6M8   W8VMI8   A0A0L7K8K9   A0A3S2NSL9   A0A2W1BQK8   A0A2A4IZ93   + More
A0A2A4J0Z3   A0A2H1VL68   A0A194RQ48   A0A194PG37   A0A212FEW5   A0A1Y1LNQ8   A0A067QSF9   A0A2J7Q265   D6WP79   A0A2P8YP14   B0WV08   A0A182GUK9   W5JS40   A0A182FJL5   A0A182W409   A0A182JWI8   Q0IFQ4   A0A182YQW8   A0A182T252   A0A182MX57   A0A182R6D4   A0A182Q024   E0W076   A0A1W4WPQ0   A0A182HIK5   Q7QEQ9   A0A182UYH1   A0A182WY66   A0A1J1J7Z5   A0A1A9WB91   A0A182JF36   B3M8Z5   A0A182N044   A0A1B0BMT9   A0A0M4EKT2   A0A1A9XD69   A0A336M1Y6   A0A336MEW4   B4H5D3   Q29ER3   A0A336MAH4   A0A1B0A764   B4KKC1   A0A3B0JY03   A0A1B0FHA3   B4QKU8   B4HVD0   A0A0J9UBA1   B4LS35   A0A1I8NXE6   B3NEM1   A0A1I8NAZ6   Q9W0T5   A0A1A9UH95   B4PC33   W8BAK3   A0A0L0BVP7   W8BFJ6   B4JQN9   B4N427   A0A182PFC5   A0A0K2SXU5  

PDB

5EIL     E-value=5.62851e-17,     Score=211

KEGG

101746226    no KO assigned | (RefSeq) BmPyrexia; transient receptor potential channel pyrexia

GO

GO:0016021   GO:0005216   GO:0006811   GO:0102568   GO:0102567   GO:0004623   GO:0048060   GO:0005261   GO:0006816   GO:0006813   GO:0009408   GO:0034703   GO:0005262   GO:0006812   GO:0051290   GO:0005515   GO:0016020   GO:0000287   GO:0043874   GO:0003677   GO:0008408   GO:0005112   GO:0015930  

Subcellular location

Membrane  

Length:

228

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.43233

Exp number, first 60 AAs:

0.00013

Total prob of N-in:

0.03694

outside

1  -  228

 

 

Pi

183.470451

Theta

164.765545

Tajima's D

0.329465

CLR

0.684989

CSRT

0.466526673666317

Interpretation

Uncertain