SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO15207  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA004963
Annotation
PREDICTED:_intron-binding_protein_aquarius_isoform_X2_[Bombyx_mori]
Full name
RNA helicase aquarius      
Location in the cell
Cytoplasmic   Reliability : 1.469 Mitochondrial   Reliability : 1.194 Nuclear   Reliability : 1.61
 

Sequence

CDS
ATGCTGAAGTTTTACGCAAGATTTGAGATTAGCGATCAGACCGGAGATCCTATGACCGACCGTGACATGACATTACAGCACTACTCAAAAATCACCTCACTACAGAAAGCCGCATTTTCCAAGTTTCCTGATCTTCGTTTATTTGCCCTCGCGAATGTAGCGAGTGTCGACACCAGAGAAACGTTGCAGAAGCACTTCAAGAATTTGAGTGACAAAGCTTTAAGAGCAATCGCCACGTACCTGAACCTGGTTCCTCCTGAAGGAAAAGAAGACGAGACGCCTTGGCACCGACTCGACAAAGATTTCCTCAGAGAGCTATTGATCTCGCGTCACGAGAGGCGAATTTCACAATTGGAAGAATTGAACTTAATGCCCCTGTATCCTACAGAAGAGATTATCTGGGACGAGAATGTAGTGCCCACAGAGATATACAGCGGAGAGAATTGCCTAGCCCTGCCTAAGCTGAATCTACAATTTTTAACATTACACGACTATCTGTTACGAAACTTCAATTTGTTCCGCTTGGAGAGCACATACGAGATAAGACAAGACATTGAAGACGCCGTATACAGATTGGCGCCGTGGAATTCAGAAGACGGAAGCGTTTATTTTGGGGGCTGGGCGCGGATGGCGCATCCTATAAAGAGCTTCGCAGTTGTCGAAGTGGCCAAACCGAACATCGGCGAGAAGGCCCCGTCGAGGGTCCGAGCCGATGTCACCGTCACGTTGAGCCTCAGAAACGAGATAAAACACGAATGGGAAAACCTCAGGAAGCATGACGTTTGCTTCCTGGTAACCGTCAGACCTACACAAGGCATAGGTACAAAGTATGACTACAGAAAGAGTATGGTGGATCAGGCGGGGATAGTGTACGTGAGGGGTTGCGAAGTTGAAGGTATGCTGGACGCATCCGGCAGAGTCATTGAGGACGGGCCGGAACCGCGGCCGGAGTTAGAGGGAGATTCCAGGACCTTCAGGCTCTTACTCGATCCTAACCAATACAGACTTGACTTGGACAGAGCTAGTAAAGGGAATGAGGACGTGTACGAGACTTTCAATATAGTTATGCGTCGTAAACCGAAAGAGAACAACTTCAAGGCCGTATTGGAAACGATACGAGAATTAATGAACACCGAATGCGTTGTACCGGACTGGCTTCACGATATAGTCTTGGGCTACGGAGATCCCGGTCAAGCTCATTACACGAGGATGCCGAACGAGATAGCTACTCTGGACTTCAACGATACATTCCTGAACATGGATCATCTGCGGAACAGCTTCCCGGGGTACGAAATCAAGGTGCAGACCAACGACCCAAGGAAGCTCGTCAGGCCGTTCAAGTTGACTTTCGAAAACGTCGTACGGAAGCAGCAGGTCGGGGACGCAGCTATGGACGAAGACGAACCCCGCAAAGCGATCATTGTCGAACCCCACGTACAACCGAAGAGGGGACCGTATTTGTACAACGAACCAAAGAAGAATAATATACTATTCACTCCGACACAAGTGGAAGCTATACGTTCTGGAATGCAACCTGGACTCACATTGGTCGTCGGTCCACCTGGAACTGGTAAAACGGACGTGGCAGTTCAAATAATTTCGAACATATACCACAACTTCCCGTGGCAACGTACCCTGGTCGTAACGCACAGCAACCAGGCCCTGAATCAGCTATTCGAGAAGGTCGCCGAGCTGGATGTAGACGAAAGGCATCTACTGCGTCTCGGTCACGGCGAGGAAGCTCTTCAGACAGACAAAGACTTCTCCAGATACGGCCGCGTGAACTATGTGTTGGCAAAGCGTCTGGAGCTGCTCGAGCTGGTGTCGCGGCTGCAGCGAACGTTGGACGCGGGCTCGGACGCCGGCGCTACGTGCGAGCTGGCGCACCACTTCCACGTCTACCACGTGCGGCCGCGCTGGCGAGCCTTCCTCGAGAACTGCCAGCAACAGACAAACTCGATTGAGATAGTCAGCAAGGAGTTTCCGTTCCACGAATTCTTCGATGATGCCCCGAAACCCTTGTTCCTGAGGAAGTCTCACGAAGAGGACATGGAAATAGCCAAAAGCTGTTACAGGTATATTGATCACATATTCGAGGAATTGGAAGAGTTCCGAGCCTTCGAACTACTGAGGTCCGGACTGGATCGGTCCAAGTACCTGTTGGTCAAAGAAGCGAAAATAATCGCGATGACGTGCACGCACGCCGCCCTCAAACGTTCCGAATTAGTGCAAATGGGTTTCAAATACGACAACATACTGATGGAGGAATCAGCTCAAATCCTCGAGATCGAGACGTTCATACCGCTGCTCCTGCAGAACCCGCAGGACGGCAGGTCCCGGCTGAAGCGTTGGATCATGATCGGCGACCACCACCAGCTGCCCCCGGTCGTCAAGAACATGGCGTTCCAGAAGTACTGCAACATGGAACAGAGCCTGTTCACCAGAATGGTCAGACTGGGTGTTCCGTACGTGGAACTGGACGCACAAGGTCGAGCTAGACCCAGCATCTGCAACCTGTACCGCTGGCGCTACCGGGCGCTGGGCGACCTGTGCCACGTGACGCAGCTCCCGGAGTACCGCGCCGCCAACGCGGGCCTGCGACACGACTTCCAGCTCGTCAACGTGGACGACTTCAACGGCGTCGGCGAGACCGAGCCCAGCCCTTACTTCTATCAGAATTTAGCGGAAGCAGAATACGTTGTAGCGGTTTTCATGTACATGCGCCTGATCGGATGGCCTGCAGAGCGCATCTCCATACTGACCACATATAACGGGCAGAAACATCTCATCAGGGACGTCATAGATAAGCGATGTGCCGATAATCCACTCATCGGTCGACCTCACAAGGTGACGACGGTAGACAAGTACCAGGGCCAGCAGAACGACATAGCTCTAGTGTCGCTGGTCCGTACGAAGGCGGTGGGTCACGTGCGCGACCTGCGGAGACTCATCGTCGCCGCCTCAAGAGCCCGTCTCGGCCTATACATATTCGCGAGGGCCAACCTCTTCAGGAACTGCTACGAGCTACAGCCTACATTCAATCAGCTCGTGGAGCGTCCACTGCAGCTTGAACTAGTCCCGGGCGAGCGGTACCCGGCGCAGCGCGCGGCGGGCGTGGCCGTGCCGCCGGAGCTGCTGCTGTCCGTCCGGGACATGCCGCACATGGCGCGCTACGTCTACGACATGTACCTGCACATTGTCAACGACGCACCCGACGCTCGACAGAGTGAATAG
Protein
MLKFYARFEISDQTGDPMTDRDMTLQHYSKITSLQKAAFSKFPDLRLFALANVASVDTRETLQKHFKNLSDKALRAIATYLNLVPPEGKEDETPWHRLDKDFLRELLISRHERRISQLEELNLMPLYPTEEIIWDENVVPTEIYSGENCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDAVYRLAPWNSEDGSVYFGGWARMAHPIKSFAVVEVAKPNIGEKAPSRVRADVTVTLSLRNEIKHEWENLRKHDVCFLVTVRPTQGIGTKYDYRKSMVDQAGIVYVRGCEVEGMLDASGRVIEDGPEPRPELEGDSRTFRLLLDPNQYRLDLDRASKGNEDVYETFNIVMRRKPKENNFKAVLETIRELMNTECVVPDWLHDIVLGYGDPGQAHYTRMPNEIATLDFNDTFLNMDHLRNSFPGYEIKVQTNDPRKLVRPFKLTFENVVRKQQVGDAAMDEDEPRKAIIVEPHVQPKRGPYLYNEPKKNNILFTPTQVEAIRSGMQPGLTLVVGPPGTGKTDVAVQIISNIYHNFPWQRTLVVTHSNQALNQLFEKVAELDVDERHLLRLGHGEEALQTDKDFSRYGRVNYVLAKRLELLELVSRLQRTLDAGSDAGATCELAHHFHVYHVRPRWRAFLENCQQQTNSIEIVSKEFPFHEFFDDAPKPLFLRKSHEEDMEIAKSCYRYIDHIFEELEEFRAFELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRSELVQMGFKYDNILMEESAQILEIETFIPLLLQNPQDGRSRLKRWIMIGDHHQLPPVVKNMAFQKYCNMEQSLFTRMVRLGVPYVELDAQGRARPSICNLYRWRYRALGDLCHVTQLPEYRAANAGLRHDFQLVNVDDFNGVGETEPSPYFYQNLAEAEYVVAVFMYMRLIGWPAERISILTTYNGQKHLIRDVIDKRCADNPLIGRPHKVTTVDKYQGQQNDIALVSLVRTKAVGHVRDLRRLIVAASRARLGLYIFARANLFRNCYELQPTFNQLVERPLQLELVPGERYPAQRAAGVAVPPELLLSVRDMPHMARYVYDMYLHIVNDAPDARQSE

Summary

Description
Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Subunit
Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE.
Similarity
Belongs to the CWF11 family.
EMBL
BABH01029882    BABH01029883    BABH01029884    BABH01029885    NWSH01001119    PCG72508.1    + More
KQ459604    KPI92324.1    KQ460045    KPJ18170.1    KZ150014    PZC74997.1    NEVH01022633    PNF18773.1    KK852653    KDR19357.1    NNAY01001737    OXU23077.1    KZ288292    PBC29091.1    KQ435736    KOX77023.1    GL446861    EFN87169.1    KQ414894    KOC59704.1    GBYB01001520    GBYB01001521    GBYB01001522    GBYB01001523    GBYB01007951    GBYB01011553    JAG71287.1    JAG71288.1    JAG71289.1    JAG71290.1    JAG77718.1    JAG81320.1    ADTU01011962    ADTU01011963    ADTU01011964    KQ982490    KYQ55807.1    GL888115    EGI67198.1    KQ981727    KYN36952.1    KQ978691    KYN29222.1    KQ976396    KYM93005.1    GL440194    EFN66172.1    AAZO01005147    DS235751    EEB16384.1    GL764129    EFZ18539.1    LBMM01002673    KMQ94494.1    KK107364    EZA51939.1    QOIP01000007    RLU20378.1    KQ434905    KZC11291.1    KQ971351    KYB26824.1    KQ977408    KYN02960.1    GEBQ01031049    JAT08928.1    GEZM01046474    JAV77210.1    CH478091    EAT33999.1    GDUN01000236    JAN95683.1    JXUM01047201    KQ561510    KXJ78338.1    GAKP01018067    JAC40885.1    AXCM01002744    GDHF01012829    JAI39485.1    GBXI01015291    JAC99000.1    AXCN02002211    GGFK01003762    MBW37083.1    GGFK01004202    MBW37523.1    GGFK01003689    MBW37010.1    JRES01000630    KNC29790.1    DS231861    EDS39463.1    ADMH02001261    ETN63350.1    GGFL01004600    MBW68778.1    APCN01002659    GAMC01016635    JAB89920.1    AAAB01008978    EGK97364.1    KB031042    ELK05567.1    AEMK02000004    EAA13627.5    GEBF01003067    JAO00566.1    GL192565    EFB17996.1    AMGL01102452    AMGL01102453    AMGL01102454    AJFE02038412    AJFE02038413    AJFE02038414    AJFE02038415    AJFE02038416    AJFE02038417    AJFE02038418    AJFE02038419    AHZZ02030743    AHZZ02030744    AHZZ02030745    AANG04001761    KN122106    KFO32908.1    AQIA01062161    AQIA01062162    AQIA01062163    AQIA01062164    AQIA01062165    AQIA01062166    AQIA01062167    JH880809    ELR58707.1    AQIB01116411    AQIB01116412    AQIB01116413    BC140525    AAI40526.1    JU477989    AFH34793.1    AFYH01147097    AFYH01147098    AFYH01147099    AFYH01147100    AFYH01147101    AFYH01147102    AFYH01147103    AFYH01147104    AFYH01147105    NBAG03000488    PNI19963.1   
Pfam
PF13087   AAA_12        + More
PF16399   Aquarius_N
PF13086   AAA_11
Interpro
IPR041677   DNA2/NAM7_AAA_11        + More
IPR027417   P-loop_NTPase       
IPR032174   Aquarius_N       
IPR041679   DNA2/NAM7-like_AAA       
IPR026300   CWF11_fam       
SUPFAM
SSF52540   SSF52540       
PDB
6QDV     E-value=0,     Score=3970

Ontologies

Topology

Subcellular location
Nucleus  
Length:
1077
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.02149
Exp number, first 60 AAs:
0.00019
Total prob of N-in:
0.00002
outside
1  -  1077
 
 

Population Genetic Test Statistics

Pi
264.891636
Theta
163.306382
Tajima's D
2.221545
CLR
0.38135
CSRT
0.91730413479326
Interpretation
Uncertain
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