Gene

KWMTBOMO15121  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004993

Annotation

putative_signal_recognition_particle_54_kDa_protein_[Bombyx_mori]

Location

Bomo_Chr25(-):5499942-5503554      View in EpiBrowser

Full name

Signal recognition particle 54 kDa protein      

Location in the cell

Cytoplasmic   Reliability : 3.484

CDS

ATGGTTTTAGCAGATTTAGGGCGTAAAATAACCACTGCTTTGCAGTCGTTGAGCAGGGCTACTATTATAAATGAAGAGGTATTGAATTCTATGCTGAAGCAGATATGTGCTGCATTATTGGAAGCAGATGTAAATATCCGCCTTGTAAAAAACTTAAGAGAAAATGTTCGCGCTGTCATTGATTTTGATGAAATGGCTGGTGGACTTAATAAGCGAAGGATGATTCAGTCTGCGGTTTTCAAAGAACTAGTCAAGCTTGTAGATCCCGGGGTTAAACCATACCAGCCCGTCAAAGGGAAGCCTAATGTAATAATGTTTGTGGGATTACAAGGATCTGGAAAGACCACAACATGTACAAAACTTGCATATCATTACCTACGTAAGAATTGGAAATCATGTTTGGTATGTGCTGACACATTCAGAGCTGGTGCTTATGATCAAGTCAAACAGAATTGTACTAAAGCCAGAATTCCGTTTTATGGAAGCTACACAGAGGTGGATCCAGTAGTAATAGCAACAACTGGAGTGGATATGTTCAAGAAGCAAGGTTTTGAAATGATTATTGTGGATACTAGTGGTCGTCATAAGCAAGAAGAGTCGCTTTTTGAAGAGATGTTGGCAGTTGCTACAGCTATTAAACCAGACAACATAATTTTTGTGATGGATGCAACAATTGGTCAAGCTTGTGAAGCTCAAGCCAGGGCTTTCAAAGACAAAGTTGATATTGGTTCTGTTATCATTACAAAGTTAGATGGACATGCAAAAGGAGGAGGTGCACTTTCGGCTGTTGCAGCTACACAAAGTCCTATCATATTCATTGGTACTGGAGAACATATTGATGACTTAGAGCCTTTCAAAACAAAACCGTTTATAAAGAAACTCCTTGGCATGGGAGACATTGAAGGTCTCTTAGATAAAGTTAATGAACTCAAACTCGATGACAATGATGAGCTACTAGAAAAACTTAAACATGGACAGTTTACTCTCAGAGCGATGTATGAACAATTTCAAAATATAATGAAGATGGGGCCTTTCTCACAAATAATGGGAATGATTCCTGGATTTTCACAAGATCTTATGTCAAAAGGAAGTGAACAAGAGTCAATGGCCAAATTAAAACTCCTTATGACAATTATGGACTCTATGAATGAAGGTGAGCTGGATAATAGAGACGGCGCCAAGTTGTTTTCTAAACAACCGACACGTATCACAAGAGTTGCACAGGGAGCAGGTGTCACAGAACGAGATGTTAAAGACTTAATTGCACAATACACAAAATTTGCGGCTGTCGTTAAAAAAATGGGTGGAATTAAAGGATTGTTCAAAGGAGGAGATATGGCTAAGAATGTTAATCAAACACAAATGGTTAAATTGAACCAACAAATGGCAAAGATGATGGATCCTCGCCTCCTACAACAAATGGGTGGTATGTCAGGTTTACACAATATGATGCGACAGCTACAACAGGGCTCAAGTGGAATGGGTGGGTTAATGGGTGGCAAATGA

Protein

MVLADLGRKITTALQSLSRATIINEEVLNSMLKQICAALLEADVNIRLVKNLRENVRAVIDFDEMAGGLNKRRMIQSAVFKELVKLVDPGVKPYQPVKGKPNVIMFVGLQGSGKTTTCTKLAYHYLRKNWKSCLVCADTFRAGAYDQVKQNCTKARIPFYGSYTEVDPVVIATTGVDMFKKQGFEMIIVDTSGRHKQEESLFEEMLAVATAIKPDNIIFVMDATIGQACEAQARAFKDKVDIGSVIITKLDGHAKGGGALSAVAATQSPIIFIGTGEHIDDLEPFKTKPFIKKLLGMGDIEGLLDKVNELKLDDNDELLEKLKHGQFTLRAMYEQFQNIMKMGPFSQIMGMIPGFSQDLMSKGSEQESMAKLKLLMTIMDSMNEGELDNRDGAKLFSKQPTRITRVAQGAGVTERDVKDLIAQYTKFAAVVKKMGGIKGLFKGGDMAKNVNQTQMVKLNQQMAKMMDPRLLQQMGGMSGLHNMMRQLQQGSSGMGGLMGGK

Description

Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).

Subunit

Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

Similarity

Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
Belongs to the GTP-binding SRP family. SRP54 subfamily.
Belongs to the peptidase S1 family.

Uniprot

H9J652   Q0N2R8   A0A212FKX0   A0A2A4JJ20   S4P9G7   A0A2H1W1X2   + More
A0A194PFU1   A0A194RQE3   V5GTI2   A0A1Y1N6I0   A0A1L8DWB8   A0A2D1QUC4   D6WFU9   A0A336MTG6   A0A1B6G6U6   U5EWA7   A0A1B6HQ90   A0A232F6T2   A0A1B6KUP8   A0A084W7T8   A0A182H825   A0A067R011   A0A0P4VUR5   A0A0V0G4F3   A0A023F5T9   T1HX96   A0A182IN25   A0A2J7Q4U6   A0A2M3ZGU9   A0A2M4A3Y4   A0A2M4BKU1   W5JS33   A0A224XF31   A0A182MHU1   A0A182YEU3   A0A1B6DF04   A0A182PQA5   A0A182UVX1   A0A182VPP8   A0A182TEC6   A0A182XDP7   A0A182LNM8   Q7Q7N8   A0A182REC2   A0A182IDF4   A0A182NMK1   A0A182QN33   A0A2M4A4B3   A0A182FP74   A0A1Q3FCN1   B0WQI7   T1PH20   A0A0A9WER6   A0A1I8NLA4   A0A088AFN8   J3JTE3   E2BWT7   A0A026WIP8   A0A0J7NJR5   E2A7N3   E0VGY3   A0A151J0I4   F4WMJ0   A0A151I0Y6   A0A195EWA8   A0A158NAE8   A0A1L8ECS0   A0A0P5YU35   A0A0P5BCW9   A0A0N7ZT08   A0A0P6INB2   E9H4K5   A0A0P5V9L8   A0A195CJY6   A0A151X4X8   A0A0N7ZWJ4   A0A0L0C9J9   A0A0P5U7R3   A0A0K8TT08   A0A2A3ECY5   A0A1A9W7G5   A0A1B0G1Y1   A0A1A9XV31   A0A1A9VJ67   A0A1B0B988   A0A1B0AEU9   A0A3L8DDN6   A0A1W4US40   D3TNF4   B4N5H4   A0A0P5TT54   A0A1J1I3V1   A0A0P5BGR2   A0A1D2NGG5   B3M3R7   A0A3B0KFM8   W8BMN5   Q29FC0   B4H1J1   A0A2S2PWQ4  

Pubmed

19121390    22118469    23622113    26354079    28004739    18362917    + More
19820115    28648823    24438588    26483478    24845553    27129103    25474469    20920257    23761445    25244985    20966253    12364791    14747013    17210077    25315136    25401762    26823975    22516182    23537049    20798317    24508170    20566863    21719571    21347285    21292972    26108605    26369729    30249741    20353571    17994087    27289101    24495485    15632085   

EMBL

BABH01030005    BABH01030006    BABH01030007    BABH01030008    DQ646413    ABH10803.1    + More
AGBW02007949    OWR54391.1    NWSH01001392    PCG71410.1    GAIX01005491    JAA87069.1    ODYU01005792    SOQ47027.1    KQ459604    KPI92251.1    KQ460045    KPJ18246.1    GALX01003534    JAB64932.1    GEZM01013898    JAV92265.1    GFDF01003539    JAV10545.1    KY285043    ATP16146.1    KQ971328    EEZ99794.1    UFQS01002172    UFQT01002172    SSX13407.1    SSX32841.1    GECZ01011716    GECZ01003614    JAS58053.1    JAS66155.1    GANO01001507    JAB58364.1    GECU01030872    JAS76834.1    NNAY01000855    OXU26190.1    GEBQ01024856    JAT15121.1    ATLV01021297    KE525316    KFB46282.1    JXUM01117524    KQ566093    KXJ70403.1    KK852804    KDR16155.1    GDKW01000821    JAI55774.1    GECL01003556    JAP02568.1    GBBI01002169    JAC16543.1    ACPB03001298    NEVH01018377    PNF23601.1    GGFM01006980    MBW27731.1    GGFK01002203    MBW35524.1    GGFJ01004546    MBW53687.1    ADMH02000585    ETN65735.1    GFTR01006802    JAW09624.1    AXCM01000109    GEDC01013014    JAS24284.1    AAAB01008952    EAA10561.2    APCN01005971    AXCN02001594    GGFK01002274    MBW35595.1    GFDL01009782    JAV25263.1    DS232041    EDS32862.1    KA647188    AFP61817.1    GBHO01040244    GBHO01040242    GDHC01014169    JAG03360.1    JAG03362.1    JAQ04460.1    APGK01034495    BT126499    KB740914    KB632005    AEE61463.1    ENN78340.1    ERL87923.1    GL451188    EFN79801.1    KK107231    EZA54974.1    LBMM01004181    KMQ92725.1    GL437365    EFN70554.1    AAZO01002262    DS235154    EEB12639.1    KQ980629    KYN14994.1    GL888217    EGI64601.1    KQ976600    KYM79474.1    KQ981954    KYN32174.1    ADTU01010270    ADTU01010271    GFDG01002367    JAV16432.1    GDIP01105337    GDIP01053410    LRGB01000146    JAM50305.1    KZS20586.1    GDIP01191592    JAJ31810.1    GDIP01215473    JAJ07929.1    GDIQ01001543    JAN93194.1    GL732592    EFX73155.1    GDIP01102541    JAM01174.1    KQ977642    KYN01041.1    KQ982519    KYQ55485.1    GDIP01205585    JAJ17817.1    JRES01000692    KNC29113.1    GDIP01116833    JAL86881.1    GDAI01000325    JAI17278.1    KZ288301    PBC28881.1    CCAG010004398    JXJN01010304    QOIP01000009    RLU18600.1    EZ422956    ADD19232.1    CH964101    EDW79613.1    GDIP01127342    JAL76372.1    CVRI01000040    CRK94973.1    GDIP01189075    JAJ34327.1    LJIJ01000047    ODN04339.1    CH902618    EDV40360.1    OUUW01000012    SPP87160.1    GAMC01004200    JAC02356.1    CH379067    EAL31335.1    CH479202    EDW30168.1    GGMS01000587    MBY69790.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000053268    UP000053240    UP000007266    + More
UP000215335    UP000030765    UP000069940    UP000249989    UP000027135    UP000015103    UP000075880    UP000235965    UP000000673    UP000075883    UP000076408    UP000075885    UP000075903    UP000075920    UP000075902    UP000076407    UP000075882    UP000007062    UP000075900    UP000075840    UP000075884    UP000075886    UP000069272    UP000002320    UP000095301    UP000095300    UP000005203    UP000019118    UP000030742    UP000008237    UP000053097    UP000036403    UP000000311    UP000009046    UP000078492    UP000007755    UP000078540    UP000078541    UP000005205    UP000076858    UP000000305    UP000078542    UP000075809    UP000037069    UP000242457    UP000091820    UP000092444    UP000092443    UP000078200    UP000092460    UP000092445    UP000279307    UP000192221    UP000007798    UP000183832    UP000094527    UP000007801    UP000268350    UP000001819    UP000008744   

PRIDE

H9J652    Q0N2R8    A0A088AFN8   

Pfam

PF01329   Pterin_4a        + More
PF01743   PolyA_pol
PF02978   SRP_SPB
PF02881   SRP54_N
PF00448   SRP54
PF00089   Trypsin

Interpro

IPR036225   SRP/SRP_N        + More
IPR036428   PCD_sf       
IPR022941   SRP54       
IPR004125   Signal_recog_particle_SRP54_M       
IPR036891   Signal_recog_part_SRP54_M_sf       
IPR003593   AAA+_ATPase       
IPR000897   SRP54_GTPase_dom       
IPR001533   Pterin_deHydtase       
IPR042101   SRP54_N_sf       
IPR002646   PolA_pol_head_dom       
IPR006325   SRP54_euk       
IPR013822   Signal_recog_particl_SRP54_hlx       
IPR027417   P-loop_NTPase       
IPR013087   Znf_C2H2_type       
IPR036236   Znf_C2H2_sf       
IPR018114   TRYPSIN_HIS       
IPR001254   Trypsin_dom       
IPR009003   Peptidase_S1_PA       
IPR001314   Peptidase_S1A       
IPR022700   CLIP       

SUPFAM

SSF55248   SSF55248        + More
SSF52540   SSF52540       
SSF47364   SSF47364       
SSF47446   SSF47446       
SSF57667   SSF57667       
SSF50494   SSF50494       

Gene 3D

1.10.260.30     1.20.120.140     3.30.1360.20    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9J652   Q0N2R8   A0A212FKX0   A0A2A4JJ20   S4P9G7   A0A2H1W1X2   + More
A0A194PFU1   A0A194RQE3   V5GTI2   A0A1Y1N6I0   A0A1L8DWB8   A0A2D1QUC4   D6WFU9   A0A336MTG6   A0A1B6G6U6   U5EWA7   A0A1B6HQ90   A0A232F6T2   A0A1B6KUP8   A0A084W7T8   A0A182H825   A0A067R011   A0A0P4VUR5   A0A0V0G4F3   A0A023F5T9   T1HX96   A0A182IN25   A0A2J7Q4U6   A0A2M3ZGU9   A0A2M4A3Y4   A0A2M4BKU1   W5JS33   A0A224XF31   A0A182MHU1   A0A182YEU3   A0A1B6DF04   A0A182PQA5   A0A182UVX1   A0A182VPP8   A0A182TEC6   A0A182XDP7   A0A182LNM8   Q7Q7N8   A0A182REC2   A0A182IDF4   A0A182NMK1   A0A182QN33   A0A2M4A4B3   A0A182FP74   A0A1Q3FCN1   B0WQI7   T1PH20   A0A0A9WER6   A0A1I8NLA4   A0A088AFN8   J3JTE3   E2BWT7   A0A026WIP8   A0A0J7NJR5   E2A7N3   E0VGY3   A0A151J0I4   F4WMJ0   A0A151I0Y6   A0A195EWA8   A0A158NAE8   A0A1L8ECS0   A0A0P5YU35   A0A0P5BCW9   A0A0N7ZT08   A0A0P6INB2   E9H4K5   A0A0P5V9L8   A0A195CJY6   A0A151X4X8   A0A0N7ZWJ4   A0A0L0C9J9   A0A0P5U7R3   A0A0K8TT08   A0A2A3ECY5   A0A1A9W7G5   A0A1B0G1Y1   A0A1A9XV31   A0A1A9VJ67   A0A1B0B988   A0A1B0AEU9   A0A3L8DDN6   A0A1W4US40   D3TNF4   B4N5H4   A0A0P5TT54   A0A1J1I3V1   A0A0P5BGR2   A0A1D2NGG5   B3M3R7   A0A3B0KFM8   W8BMN5   Q29FC0   B4H1J1   A0A2S2PWQ4  

PDB

6FRK     E-value=0,     Score=1938

KEGG

778481    K03106 signal recognition particle subunit SRP54 [EC:3.6.5.4] | (RefSeq) Srp54; signal recognition p

PATHWAY

03060    Protein export - Bombyx mori (domestic silkworm)

GO

GO:0006729   GO:0005525   GO:0008312   GO:0006614   GO:0008124   GO:0016779   GO:0048500   GO:0003924   GO:0006396   GO:0005786   GO:0006616   GO:0005829   GO:0030942   GO:0004252   GO:0000166   GO:0003677   GO:0008408   GO:0005112   GO:0015930  

PANTHER

PTHR11564  

Subcellular location

Cytoplasm  

Length:

501

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0273399999999999

Exp number, first 60 AAs:

0.00023

Total prob of N-in:

0.00278

outside

1  -  501

 

 

Pi

14.990922

Theta

18.742286

Tajima's D

-0.614738

CLR

22.572305

CSRT

0.221638918054097

Interpretation

Uncertain