SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO15069
Pre Gene Modal
BGIBMGA004825
Annotation
PREDICTED:_DNA_polymerase_epsilon_catalytic_subunit_A_[Amyelois_transitella]
Full name
DNA polymerase epsilon catalytic subunit      
Location in the cell
Nuclear   Reliability : 2.352
 

Sequence

CDS
ATGGTGCTTCAAAATACTGGAAAATACCGACCCGATAAAGATGATTCTGCTAGAAGAGAAGGAACTTCTTCAGGTGGGCTCAAGGAAGAGTCATCGGAAACTAGAATTCGTGCCGCTCTGGAGAATGACAGAATTGACTCAAAGTATGGTTTCGATCGAGTGAGAGATTTAAAAGAAAGGACTGGCTACTTGATCAATATGCACACGGCTGAGGTACTCGATGAAGACAAACGATTAGTTGCTGCCATGGATTACTATTTCATAGAGATGGACGGTACCAGATTCAAAATTTCATTAATGTTTCAACCATATTTTCTAATAATGGCCAGAAGAGAATGTGAACAGGAAGTTATACAATACATCTCTAAGAAGTTTGCTAGTTCAGTGCAAAAGATTGAAGTATTGGAGAAGGAAGATTTGGACTTGATGAACCACTTATCAGGTCTGAAACAGCGTTACATAAAATTATCATTTATGTCTCAAAATGATATGATGAAAGTCCGACGGGAGATATTGACGGCAGTTAATAAAAATAAAGAGCGGGAAAAGAAAGATGTTATTTATGCTGAAATGTTAACTAATGCATTAACCAGTGCAGCAGCTATCGAACACGCTAAGAAAACTACTGATCACATGGAAAATATTTTGGACATCCGGGAACATGATGTGCCATATCATGTAAGAGTCTCTATAGACATGAGAATATTCTGTGGCACATGGTACACAGTGAAATGCAGAGGTACTGACCCTCCTATTTTCACAAAACGAGATGACATCATCGAGAGACCAGATCCTATAGTATTGGCCTTTGATATAGAAACTACAAAACTACCATTAAAGTTTCCAGACTCGCAAACAGATCAAATAATGATGATCTCTTACATGATCGATGCACAGGGGTACTTAATAACAAACAGAGAAATTATATCGGTCGACGTTGAAGACTTTGAATATACTCCTAAACCGGAATTTGAAGGCCAATTCATAGTATTTAATGAACCAAATGAGCTGGCACTTATACAGAAGTTTTTCGATCATATCATGGATGTGAAACCACACATCTTTGTCACATATAACGGTGATTTCTTCGATTGGCCATTTGTGGAAGCTCGTGCCGCGATTCTAGGGCTGGACATGAAGCAGGAGATAGGGTTCAGTAAGGTGACGTCACGCGACAACACGTACGTCTGCAGACCTGCGATGCACATGGACTGCTTATGCTGGGTGAAAAGAGACTCGTATCTGCCGGTCGGCTCGCAGGGCCTGAAGGCGGTCGCTAAAGCCAAGCTGAGGTACGACCCCGTCGAGCTGGACCCTGAAGACATGTGCAGGATGGCGTCCGAACAGCCTCAGGTGCTGTCGAACTACTCGGTGTCGGACGCGGTCGCCACGTACTACTTGTACATGAAGTACGTGCATCCGTTCATATTTGCCCTCTGCACCATTATCCCGCTGGAGCCCGACGAGGTACTCCGGAAAGGTTCCGGCACGCTGTGCGAGTCGTTGCTGATGGTCGAGGCGTTCCATGCGAACATCGTGTTCCCGAACAAGCAGGTGGAGGAGCTGAACAAGCTGACGAGCGACGGGCACGTGCTGGAGACGGAGACTTACGTCGGGGGACACGTCGAGGCTCTGGAGTCCGGTGTATTCAGAGCGGACATTAAATGCAAGTTCCGTATCGCCCCAACGGCCGTGGACAAGCTGCTGGAGAACACCGAGAAGACCATGAGGCACGCCATAGAGGTGGAGGAAGGTATACCGCTGGAGATGGTCACGAATTTCGACGAGGTCTGCGGAGAGATTAAAGCGAAACTACAACATATGAAAGAGCACCCGCGAAGGGACGAGAACCCTTTGATTTATCATTTGGACGTCGGCGCTATGTACCCTAACATCATATTGACGAATAGATTGCAGCCCTCTGCGATGGTGAATGCCAGTACATGCGCCGTCTGTGACTACAACAAGCCCGGGGCCACTTGCCAGAGACACATGGAGTGGATGTGGCGCGGGGATTACTTACCGGCTACGAGGAGCGAGTACCAACGTATACAGCAGCAGCTGGAAACTGAAAAATTTCCACCTCTACATCCTGGGGGTCCACCCAGGCCCTTCCACACGCTGCCGAAAGAGGAACAGGCTGCGTACGAGAAAAAACGATTAGCGGATTACTGCAAGGTCGCGTATAAGAAAACCAAAGTTACTAGAAGTGAAATAAGAACAACCACTATATGCCAGAAGGAGAACTCTTTCTATGTGGATACTGTACGTGCGTTCAGAGATCGTCGTTACGAATACAAAGCTCTGAACAAGCAAGCGAAAGCGAAGGTCTCCGAGGCGGTTGCTAGCGGAGACGCGGCGGAGATCAAATCCGCCAAAAGCAGAGAAGTTTTGTACGATTCACTGCAATTGGCACATAAATGTATTCTCAATTCTTTCTATGGCTACGTCATGAGGAGAGGTGCTCGATGGCACAGCATGGAGATGGCGGGGATCGTGTGCTACACGGGCGCCAACATCATCATGCGCGCTCGGGAGATCATCGAACAAGTTGGCAGACCGCTCGAGTTGGATACTGACGGTATCTGGTGCATATTACCGTCATCGTTCCCAGAAAACGTGACCATCCACACGAATCATCCGAAGAAAAAGAAGATTAATGTTTCCTTCCCTAACGCTGTACTCAATGCAATGGTTAAGGATCATTTTACAAACGACCAGTACTTCGAACTCGTGGATCCGGAACAGAAGAGATACGAGCAGCGCTCGGAAAACTCGATATTCTTTGAAGTGGACGGCCCTTACTTGGCCATGGTGTTGCCGGCTTCTAAAGAAGAAGGCAAAAGGTTGAAGAAGCGTTATGCCGTCTTCAATTTTGACGGGTCATTAGCTGAATTAAAAGGTTTCGAAGTAAAACGTCGCGGCGAACTGCAACTCATCAAAATATTTCAATCTTCCGTATTCGAGGCCTTCCTCAAAGGTAACGATCTGAAGTCGTGCTACGGCGCCGTGGCCCGGGTCGCGGACTATTGGCTGGACGTGCTGTACAGCCGGGGCTCCAACATGCCCGACGCCGAACTCTTCGAGTTGATATCGGAGAACCGTTCCATGTCCAAGAAGCTGGAGGATTACGGCGGACAGAAGTCTACGTCGATATCGACCGCCAAGAGACTGGCCGAGTTCCTCGGTGATCAGATGGTCAAGGACGCCGGCTTGGCTTGCAGATTCATAATATCGAAGAAGCCCGAGGGTGCTCCGGTGACGGAACGAGCGATCCCGCTCGCCATCTTCCAGTCGCCGGCCGCCGTGAAGCGGCACCACCTGCGGCGCTGGCTCAAGGACTCCAGCGTCTCCGAGCACATCGACATCCGCGACGTGCTGGACTGGGCCTACTACATCGAGAGGCTCAGCGGGGCCATACAGAAGATCATCACCATACCGGCCGCCATGCAAGGCTTGGACAATCCGGTGCCCCGGGTACAGTACCCGGATTGGTTGCACAAGAAGATGCTCGCCAAAACGGATAAGTACAAAACGAGGAAGATCACGGACATGTTCAGCGCGCAGCCCAGGGAACTACGCACCGTGGAGGAAGACGCGGAGGAAGCCGCTGGTGCTGATACCTCGAACACAGAAATGGACATGGAAGACATTGGCAATGACAAGACAGGGAGGGCCACAATAATTCGTCCGGTAGTGCACACTATGAAGAGGAAGCGGACTGAATCTCCGCCTCAAGACGCCGCCGCCACGTGGAGAGAGGCGCTGGGACCTCCGCCGCCTTTCGGAAATACTAAGGAAGAACGAAGAAATTGGATTTTGTTTCAAAAAAGAAAATGGCTGTGGCAAATGGAGCAACGTGGCTTAAGAAATCGAAACAAACGAGGTAAAATTGACAGTGACATAATGCCGCCGCCGAGGAGTTCCGGGCCGGCCGCCACGTTAGGTAGTTTTATCAGGAGAGCACAGCGCACCTTGTTGAATACACCATGGCAAATTATACAGGTAGCGGAAACAGCCGAGCCGGGGCTGTTCAAGGTGTGGGCGCTGGTGGGCGCCGAGCTGCACCAGGTGAAGGTGTCGGTGCCGCGCGTGTTCTACGTGAACCAGCGCGTGTGCCGCGGCGCCGACAGCGGCCGCTACTGGCGCCGCTGCAGCCGCCTGCTGCCCCGCGCGCACCCCGTGCTGCACCTCTACCAGTACTCCGTGCCCGAACAGCTCTACAGGGAACATCAGGAAGAGCTCATGGGTGAATTATCGGCTCCGGAAATAGAAGGTATTTACGAGACACAGATGAGCTTAGAGTTCAGGATTCTGGTACAACTCGGATGTATCTGCGCTGTGGAGCCGCAAGAGGCGAGACGAATGATACAGTTCGGTTCAAACAATATGGATTCGTTTACGTTGAATCAACTACAGTTCAAGAGTGTCGCACATCAACCTTACTTACCGAAGCAGGATGGACAGTTTCCGATTAAACACATATTCCTGTACCAGCATTCGTCTGTGAATTCCAGTCGCAGTATGTGGGCATTGATACTGGGTCCTCTGAAAAAAGGATATATTTTCGTACAGGACACGGTCAAGACCAATCAAGTACCTAACATGAGCACCCTTTACGCAGCCGAAAGGACAGCTAAAATAAATCAAGGGACAGACGAGAACACGCTGCCGGGCCCTGAGTTGTCGTGGGAGGTGGTGGTGGAGAGCTCGACGCGCGCGCTGTGCCGCGGGCTGCAGGCGGCGCTGGGCCGCGGCCGCACGGAGCGCGCGGGGCCGGCGCTGCTGGCCGTGCAGGCCGCGCTCTCGCTGCCCGCCCTCACTGCGCTCATGCCCGGTCTGGTTGACTACCCGATAGTGCCGCTGCACGTCCGCGACGTGGAGACCCTGTACAACACGTTGGAGTGGCAGAGGATAGGCGCGAGGGCCATCGTCAGGCACTACCTCAACTTGGAGTCGGTGCTGGCGCTCACCATCGAGCAGTGCAGATATTTCCACGTGCCGCTGGGCAACATGCCGGCGGACCCGACGCTGTTCGGCGCGGACCTGTTCTACGCCCGCCACCTCGTCAAGCACAACTTCGTGCTCTGGTGCTCCAACCTCGAACGTCCGGACCTCGGAGGGAGAGAGATCGACGATAATAGACTGGCGAGCGAGGCGGAGGAGGGCGGGGCGTGGAGCGGCGGCGCGGGCGGCGCGCACGGCGGCGTGTGCGTGGAGCTGGGGCTGGACGCGCTCAGCGTGTGCGCGCTGCTGCAGGCGCACCTCGTGCTGCAGGCGGAGGGCACCAGCGCCGCCACCGCCTTCGGGCACGCGCCCACCAGTCTACAGCACCTGCTCGACAACACCGGTCCGAACGCGTCCCTCAACTACGACGAGGCGGCTCAGTGCAGCGCCGCCTTCAAGATCCTGAGGACGATGGTCGCGTCCTGGCTCCGTGACGTCACGCAATACAAAAACGTCTTCGCAGACTTCCAAATAACGCACTTCTACAGGTGGTTAAAAACGCCGACGTCTCTGCTGTACGACCCGGCGCTTCGGCGCACCCTGTACAACCTGATGAAGAAGCTGTTCCTGATGCTGCTGGCGGAGTTCAGGCGGCTGGGCTCGGTGCTCGTGCACGCCGACTTCAACAAGATCCTGCTCAGCACTAAGAAGACTTCGGTCGTCGACGGAATAGGATACGTAGAATTCGTAGTGCAGAGCATAAGGAATAAGGAACTGTTCCACGGCATCGATATTAGGTACCGGCAGTGCTGGGTGCATCTGCTGTGGCTCGACGAGGCCAACTATGCGGGGATACAGGGTAAACTTCCGGAAGGCTTAACTGAAGTGGGATCTTCTCAAGTTCCTCCGAGCAACAACGAGGATGGCGACACTGATGAGGAGAGTTCGATAGTGATGCACTGGAACCTGGCCAAGTTCCTGCCGGGCTTCGTCCGGGAGCAGTTCGTGTCCGCCGTGGCCGGGTACCTGGCCGCCGCCCGCACGCGCCCCGCCGACCTGCCCGCCCTGCTGCGCGGCGAGATCTCACAGAAACTGTTCCGAGTAACGGAGAAGATAAACTCGCGGATGCCGACGCTCCGGCTGTCGGACATCGGGCCGCAGCCCGGCCTCAAGGCGGACGCGCTCAGTGACGTCACGCCCGCCCTGCTCTTCGTCAACGCCGTCTGCAAAGTGTTCTCCCTCGATCCGACCTTAGACGAAGAGATGACGCTGGTGCGGCGCAACCTGCTCCGTCTGATCGGCGTGGGCGAGTTCAGCAGCGCGGCGGAGTGGCGCGAGCCGTGCGCCGCGTGCGTGCTGACCGAGCTCACGTGCCGCGTGTGCAACCACTGCCGCGACCTCGACCTGTGCAGGGACGCGCGAGACGACACGGAACGTCCGGCGTGTTTATGTCCAACTTGTGGAACAGCATATGATAATCAGGAAATAGAATGGCGACTAATCGAGACGATGAACAAACGTACGATGGCGTATACGCTGCAAGATCTTATATGTAGCCGATGTCACCAGGTAAAACGTGAGAATTTGTCTGTGGTCTGTGATTGTGCTGGAGATTTTTCGCTGATGGTTCCCGTAACAGAGATCAAAGACCAACTAATGACTTTTAAGACAATAGCCGAATATTATCAGATGCCATTATTGTTAGAACAAATTGACTTTAATCTTAAAAACATGTGA
Protein
MVLQNTGKYRPDKDDSARREGTSSGGLKEESSETRIRAALENDRIDSKYGFDRVRDLKERTGYLINMHTAEVLDEDKRLVAAMDYYFIEMDGTRFKISLMFQPYFLIMARRECEQEVIQYISKKFASSVQKIEVLEKEDLDLMNHLSGLKQRYIKLSFMSQNDMMKVRREILTAVNKNKEREKKDVIYAEMLTNALTSAAAIEHAKKTTDHMENILDIREHDVPYHVRVSIDMRIFCGTWYTVKCRGTDPPIFTKRDDIIERPDPIVLAFDIETTKLPLKFPDSQTDQIMMISYMIDAQGYLITNREIISVDVEDFEYTPKPEFEGQFIVFNEPNELALIQKFFDHIMDVKPHIFVTYNGDFFDWPFVEARAAILGLDMKQEIGFSKVTSRDNTYVCRPAMHMDCLCWVKRDSYLPVGSQGLKAVAKAKLRYDPVELDPEDMCRMASEQPQVLSNYSVSDAVATYYLYMKYVHPFIFALCTIIPLEPDEVLRKGSGTLCESLLMVEAFHANIVFPNKQVEELNKLTSDGHVLETETYVGGHVEALESGVFRADIKCKFRIAPTAVDKLLENTEKTMRHAIEVEEGIPLEMVTNFDEVCGEIKAKLQHMKEHPRRDENPLIYHLDVGAMYPNIILTNRLQPSAMVNASTCAVCDYNKPGATCQRHMEWMWRGDYLPATRSEYQRIQQQLETEKFPPLHPGGPPRPFHTLPKEEQAAYEKKRLADYCKVAYKKTKVTRSEIRTTTICQKENSFYVDTVRAFRDRRYEYKALNKQAKAKVSEAVASGDAAEIKSAKSREVLYDSLQLAHKCILNSFYGYVMRRGARWHSMEMAGIVCYTGANIIMRAREIIEQVGRPLELDTDGIWCILPSSFPENVTIHTNHPKKKKINVSFPNAVLNAMVKDHFTNDQYFELVDPEQKRYEQRSENSIFFEVDGPYLAMVLPASKEEGKRLKKRYAVFNFDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGNDLKSCYGAVARVADYWLDVLYSRGSNMPDAELFELISENRSMSKKLEDYGGQKSTSISTAKRLAEFLGDQMVKDAGLACRFIISKKPEGAPVTERAIPLAIFQSPAAVKRHHLRRWLKDSSVSEHIDIRDVLDWAYYIERLSGAIQKIITIPAAMQGLDNPVPRVQYPDWLHKKMLAKTDKYKTRKITDMFSAQPRELRTVEEDAEEAAGADTSNTEMDMEDIGNDKTGRATIIRPVVHTMKRKRTESPPQDAAATWREALGPPPPFGNTKEERRNWILFQKRKWLWQMEQRGLRNRNKRGKIDSDIMPPPRSSGPAATLGSFIRRAQRTLLNTPWQIIQVAETAEPGLFKVWALVGAELHQVKVSVPRVFYVNQRVCRGADSGRYWRRCSRLLPRAHPVLHLYQYSVPEQLYREHQEELMGELSAPEIEGIYETQMSLEFRILVQLGCICAVEPQEARRMIQFGSNNMDSFTLNQLQFKSVAHQPYLPKQDGQFPIKHIFLYQHSSVNSSRSMWALILGPLKKGYIFVQDTVKTNQVPNMSTLYAAERTAKINQGTDENTLPGPELSWEVVVESSTRALCRGLQAALGRGRTERAGPALLAVQAALSLPALTALMPGLVDYPIVPLHVRDVETLYNTLEWQRIGARAIVRHYLNLESVLALTIEQCRYFHVPLGNMPADPTLFGADLFYARHLVKHNFVLWCSNLERPDLGGREIDDNRLASEAEEGGAWSGGAGGAHGGVCVELGLDALSVCALLQAHLVLQAEGTSAATAFGHAPTSLQHLLDNTGPNASLNYDEAAQCSAAFKILRTMVASWLRDVTQYKNVFADFQITHFYRWLKTPTSLLYDPALRRTLYNLMKKLFLMLLAEFRRLGSVLVHADFNKILLSTKKTSVVDGIGYVEFVVQSIRNKELFHGIDIRYRQCWVHLLWLDEANYAGIQGKLPEGLTEVGSSQVPPSNNEDGDTDEESSIVMHWNLAKFLPGFVREQFVSAVAGYLAAARTRPADLPALLRGEISQKLFRVTEKINSRMPTLRLSDIGPQPGLKADALSDVTPALLFVNAVCKVFSLDPTLDEEMTLVRRNLLRLIGVGEFSSAAEWREPCAACVLTELTCRVCNHCRDLDLCRDARDDTERPACLCPTCGTAYDNQEIEWRLIETMNKRTMAYTLQDLICSRCHQVKRENLSVVCDCAGDFSLMVPVTEIKDQLMTFKTIAEYYQMPLLLEQIDFNLKNM

Summary

Description
DNA polymerase II participates in chromosomal DNA replication.
Catalytic Activity
a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
Cofactor
[4Fe-4S] cluster
Similarity
Belongs to the DNA polymerase type-B family.
Feature
chain  DNA polymerase epsilon catalytic subunit
EC Number
2.7.7.7
EMBL
KQ459604    KPI92202.1    NWSH01001797    PCG70113.1    GEBQ01012620    JAT27357.1    + More
GBHO01017841    JAG25763.1    GDHC01015926    JAQ02703.1    PYGN01000288    PSN49238.1    GFTR01008948    JAW07478.1    ACPB03018895    ACPB03018896    KQ971352    EFA06672.2    CH902617    EDV42489.2    CM000160    EDW98127.1    CH954182    EDV54022.1    KZ288282    PBC29548.1    AE014297    AAF56126.3    JN600259    AEO27699.1    CH964232    EDW81769.1    CP012526    ALC46025.1    CM000070    EAL27015.2    CH916373    EDV94360.1    GEZM01097888    JAV54063.1    DS232010    EDS31604.1    OUUW01000005    SPP80144.1    KQ434825    KZC07383.1    GFDL01015666    JAV19379.1    CH940650    EDW67834.1    KK107131    EZA58200.1    GDHF01003910    GDHF01001248    JAI48404.1    JAI51066.1    GL439339    EFN67414.1    CH477253    EAT45963.1    GBXI01002536    JAD11756.1    ATLV01021314    KE525316    KFB46291.1    LNIX01000002    OXA59881.1    CH933806    EDW14644.1    GL446286    EFN88114.1    APGK01034997    KB740923    ENN78133.1    KB632326    ERL92417.1    JRES01000196    KNC33370.1    LBMM01000967    KMQ97138.1    AXCN02002212    UFQT01002288    SSX33110.1    AB035512    BAB17608.1    GFXV01006930    MBW18735.1    KQ981305    KYN42982.1    QOIP01000012    RLU15884.1    GBYB01001082    GBYB01001085    JAG70849.1    JAG70852.1    ABLF02028722    ABLF02028723    AXCM01000127    APCN01005975    AAAB01008952    EAA10584.4    UFQS01001708    UFQT01001708    SSX11917.1    SSX31479.1    KB202367    ESO90687.1    GDIP01052482    LRGB01000311    JAM51233.1    KZS19812.1    GFPF01007277    MAA18423.1    ADMH02001905    ETN60560.1    KQ980734    KYN13843.1    GL888529    EGI59695.1    GDIQ01035048    JAN59689.1    KQ982446    KYQ56328.1    GDIQ01003618    JAN91119.1    CCAG010021212    CH479186    EDW38877.1    GDIP01145265    JAJ78137.1    KQ978009    KYM98131.1    GDRN01091450    JAI60272.1    NNAY01001764    OXU22982.1    JXJN01004168    ADTU01010057    CVRI01000039    CRK94685.1    KQ976455    KYM85157.1    QCYY01000848    ROT82296.1    LJIJ01000049    ODN04259.1    NEDP02000736    OWF55201.1    KQ435727    KOX77830.1    GEDV01001734    JAP86823.1    GL766762    EFZ14659.1    GL732601    EFX72310.1    GDIQ01189433    JAK62292.1    DS235751    EEB16354.1    AERX01026863   
Pfam
PF08490   DUF1744        + More
PF03104   DNA_pol_B_exo1
PF00136   DNA_pol_B
Interpro
IPR006133   DNA-dir_DNA_pol_B_exonuc        + More
IPR006172   DNA-dir_DNA_pol_B       
IPR006134   DNA-dir_DNA_pol_B_multi_dom       
IPR036397   RNaseH_sf       
IPR013697   DNA_pol_e_suA_C       
IPR042087   DNA_pol_B_C       
IPR012337   RNaseH-like_sf       
IPR029703   POL2       
IPR000782   FAS1_domain       
IPR023211   DNA_pol_palm_dom_sf       
SUPFAM
SSF53098   SSF53098       
Gene 3D
PDB
4M8O     E-value=0,     Score=3181

Ontologies

Topology

Subcellular location
Nucleus  
Length:
2227
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.0692199999999995
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00320
outside
1  -  2227
 
 

Population Genetic Test Statistics

Pi
287.730411
Theta
184.973034
Tajima's D
2.103974
CLR
0.289027
CSRT
0.899455027248638
Interpretation
Uncertain
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