Gene

KWMTBOMO15060  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004852

Annotation

PREDICTED:_protein_transport_protein_Sec23A_isoform_X1_[Papilio_machaon]

Location

Bomo_Chr25(-):3777698-3786362      View in EpiBrowser

Full name

Protein transport protein SEC23      

Location in the cell

Nuclear   Reliability : 1.99

CDS

ATGGCCACATACGAGGAGTTCATCCAGCAGAATGAAGACCGCGATGGCATACGGTTCACTTGGAACGTATGGCCATCAAGTAGAATTGAGGCTACGAGGCTTGTTGTGCCTTTGGCTTGCTTGTACCAACCGCTTAAGGAGCGCCCCGACCTACCACCGATACAGTACGAGCCTGTACTCTGTACACGAAATACATGCAGAGCTATATTGAACCCAATGTGCCAGGTGGATTACAGAGCTAAATTATGGGTCTGCAACTTTTGCTTCCAACGAAACCCATTTCCACCTCAATATGCTGCTATATCAGAACAGCATCAACCTGCAGAACTGATTCCTAACTTTTCCACCATAGAGTACACAATAACGCGAGCACAGGCTATGCCCCCAATCTACCTGCTTGTTGTTGATACTTGTTTAGATGAGGAAGAACTTGGGGCACTCAAAGATTCCTTGCAGACTTCACTTAGTTTAATGCCTCAAAATGCACTCGTTGGACTAATAACATTTGGTAAAATGGTACAGATTCATGAATTAGGTACAGAAGGCATATCAAAATGCTATGTTTTCAAAGGAACAAAAGATTTGTCAGCAAAGCAAATTCAAGAGCAACTAGCTATTGGCCGTGTGAATGCACCAAATCCTCAGCAGCAGCGTCCTGGTGCTCCTGTTCCACAGCCTCCAGCTCACAGATTCTTGCAGCCAGTCAAACAATGTGATATGTCATTAACTGACCTGCTCGGTGAACTTGGGAGGGATCCTTGGCCCTTAGGTGTTGGAAAGAGACCCTTACGTAGTAGCGGAGTAGCACTTTCATTGGCTGTTGGATTACTGGAAGTTACATATCCCAACACCGGCGCAAGAATCATGATGTTCCTAGGTGGACCATGTTCTCAGGGACCAGGTCAGGTTGTGAATGATGAGTTGAAACAGCCCATCCGATCCCATCATGACATTCATAAGGATAATGCTAAATATATGAAAAAGGCTATTAAACATTATGAAGCTTTGTCTCTAAGATCAGCAACAAATGGTCATTCCATAGATATTTACTCATGTGCTTTGGATCAGACTGGCCTGATGGAAATGAAACAGTGCTGTAATTCTACTGGAGGTCACATGGTGATGGGAGACTCGTTCAATTCATCTCTGTTCAAACAGACGTTCCAAAGAGTGTTCGCTAAAGACACAAAAGGAGATTATAAGATGGCATTCAACGGTACTTTAGAAGTCAAATGTAGCCGTGAACTGAAAATATCTGGTGCGATTGGTTCCTGCGTGTCTCTGAATGTGAAGGGACCGTGCGTATCTGATCAGGAGGTCGGAATGGGCAACACGTGTCAATGGAAGCTATGTACTTTCACCCCCAGTACTACCATGTCCATATTCTTTGAGGTTGCAAACCAAGCTTCGACGGTACCCCAAGGTGGTCGCGGCTGCGTACAGTTCATCACGCAGTACCAGCACTCGAGCGGACAGAGACGCGTCCGAGTCACAACAGTGGCTAGAAACTGGGGCGACGCAGCGGTGAGTCTCCATCACATAGCGGCCGGCTTCGACCAGGAGGCGGCCGCCGTGGTGATGGCGCGGCTCGTGGTCTACCGCGCCGAGATCGAGGATGGGCCTGACGTGCTGCGCTGGCTCGACCGGATGCTCATACGATTGTGCCAGAAGTTCGGTGAATACGGCAAAGACGATCCGAACAGCTTCCGCCTGTCGGAGAACTTCAGTCTGTACCCGCAGTTCATGTACCATCTCCGACGCTCGCAATTCCTTCAGGTCTTCAACAACTCACCGGACGAGACCACATTCTATAGGCACATGTTGATGCGTGAAGATCTGACCCAGTCTCTGATCATGATCCAGCCGATCTTGTACTCGTACAGCTTCGGAGGTCCCCCGGAGCCGGTACTCTTGGACACGTCCTCCATACAAGCGGACCGCATACTCCTGATGGACACCTTCTTCCAAATATTGATATATCACGGCGAGACGATAGCACAATGGCGGGCCCTGCGCTACCAAGACATGCCGGAGTACGAGAGCTTCGCGCAGCTGCTGCGGGCGCCCGTGGACGACGCGCAGGAGATCCTGCAGAGCAGGTTCCCGGTGCCCCGGTACATCGACACGGAGCACGGCGGCTCGCAGTAA

Protein

MATYEEFIQQNEDRDGIRFTWNVWPSSRIEATRLVVPLACLYQPLKERPDLPPIQYEPVLCTRNTCRAILNPMCQVDYRAKLWVCNFCFQRNPFPPQYAAISEQHQPAELIPNFSTIEYTITRAQAMPPIYLLVVDTCLDEEELGALKDSLQTSLSLMPQNALVGLITFGKMVQIHELGTEGISKCYVFKGTKDLSAKQIQEQLAIGRVNAPNPQQQRPGAPVPQPPAHRFLQPVKQCDMSLTDLLGELGRDPWPLGVGKRPLRSSGVALSLAVGLLEVTYPNTGARIMMFLGGPCSQGPGQVVNDELKQPIRSHHDIHKDNAKYMKKAIKHYEALSLRSATNGHSIDIYSCALDQTGLMEMKQCCNSTGGHMVMGDSFNSSLFKQTFQRVFAKDTKGDYKMAFNGTLEVKCSRELKISGAIGSCVSLNVKGPCVSDQEVGMGNTCQWKLCTFTPSTTMSIFFEVANQASTVPQGGRGCVQFITQYQHSSGQRRVRVTTVARNWGDAAVSLHHIAAGFDQEAAAVVMARLVVYRAEIEDGPDVLRWLDRMLIRLCQKFGEYGKDDPNSFRLSENFSLYPQFMYHLRRSQFLQVFNNSPDETTFYRHMLMREDLTQSLIMIQPILYSYSFGGPPEPVLLDTSSIQADRILLMDTFFQILIYHGETIAQWRALRYQDMPEYESFAQLLRAPVDDAQEILQSRFPVPRYIDTEHGGSQ

Description

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.

Similarity

Belongs to the SEC23/SEC24 family. SEC23 subfamily.

Uniprot

H9J5R2   A0A2W1BXB0   A0A0N1I9D7   A0A2A4JPS7   A0A194PFX2   A0A1E1WGU3   + More
S4PSB0   D6WT99   A0A139WFB6   A0A2D1QUK3   A0A336MH18   A0A336MWW3   E0VYI1   U5EZI3   A0A2J7RPU3   A0A2J7RPV0   A0A1I8NGE3   A0A1I8NGC8   A0A1B6D2P7   A0A1B0CEZ0   A0A1B6D2Y3   A0A1W4WSA3   A0A1W4WG52   Q171Y9   A0A0Q9W0Y2   A0A0M4F682   A0A0Q9X5J3   A0A2M3YZ76   B4N9Z7   A0A1Y1K6B6   B4M3T5   A0A2M4A1T9   A0A2M4BER3   Q171Z0   A0A1I8Q6S2   A0A0K8TSA6   W5JNW3   A0A0Q9WD23   A0A1I8Q6M9   A0A2M4A1T5   A0A2M4BEN3   A0A182GSS4   A0A182FNT3   Q9NFN9   A0A3B0KMV7   A0A0B4K5Z8   B4JEV8   Q9VNF8   A0A0B4K6T4   A0A3B0KHK3   A0A0R1E5B3   B4PUW0   B5DXU4   I5ANM9   A0A3B0KRP7   A0A182M2K5   A0A182NLI1   A0A0T6BAD1   T1DFV5   A0A182IPZ5   B0WDJ1   Q8IGT0   A0A067RMD5   A0A1Q3FEV9   A0A1Q3FET2   A0A0L0BYD7   A0A182SSY1   A0A182Q724   H6WAQ8   A0A1A9W888   B4K8H5   A0A0Q9WZ29   U4TRT6   N6U7X9   A0A0C9R009   J3JX23   A0A084W568   A0A0C9RM98   A0A182VRR7   A0A182JXQ9   A0A1A9UN52   A0A1B0AA87   A0A034VCZ7   D3TRS5   B3P2H8   A0A0P8YCW4   A0A034VE33   A0A1J1I3K2   A0A1W4UWI1   B3LWP1   A0A182NZD3   A0A0K8SP95   A0A1W4UJI9   A0A1A9XHP0   A0A1B0B9K9   A0A0K8TX82   A0A0K8UGG8   A0A0K8TXV2   A0A182VAG9   A0A182WSX3  

Pubmed

19121390    28756777    26354079    23622113    18362917    19820115    + More
20566863    25315136    17510324    17994087    28004739    26369729    20920257    23761445    26483478    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    15632085    24845553    26108605    23055932    25244985    23537049    22516182    24438588    25348373    20353571    18057021    26823975   

EMBL

BABH01025035    KZ149918    PZC77837.1    KQ460594    KPJ13930.1    NWSH01000949    + More
PCG73410.1    KQ459604    KPI92192.1    GDQN01004852    JAT86202.1    GAIX01000095    JAA92465.1    KQ971352    EFA06320.2    KYB26644.1    KY285048    ATP16151.1    UFQT01001063    SSX28701.1    UFQT01003484    SSX35044.1    DS235845    EEB18437.1    GANO01000744    JAB59127.1    NEVH01001355    PNF42857.1    PNF42856.1    GEDC01017326    JAS19972.1    AJWK01009472    GEDC01017305    JAS19993.1    CH477443    EAT40797.1    CH940652    KRF78778.1    CP012526    ALC47525.1    CH964232    KRF99527.1    GGFM01000812    MBW21563.1    EDW81752.1    GEZM01094265    GEZM01094264    JAV55750.1    EDW59296.1    GGFK01001390    MBW34711.1    GGFJ01002342    MBW51483.1    EAT40796.1    GDAI01000364    JAI17239.1    ADMH02001019    ETN64439.1    KRF78779.1    GGFK01001391    MBW34712.1    GGFJ01002375    MBW51516.1    JXUM01017361    JXUM01017362    JXUM01017363    JXUM01088536    JXUM01088537    JXUM01088538    KQ563708    KQ560481    KXJ73457.1    KXJ82200.1    AJ276482    CAB81549.1    OUUW01000013    SPP87919.1    AE014297    AFH06251.1    CH916369    EDV93239.1    AAF51978.2    AFH06253.1    SPP87920.1    CM000160    KRK03950.1    EDW97767.1    CM000070    EDY67910.1    EIM52564.1    SPP87921.1    AXCM01000497    LJIG01002650    KRT84290.1    GAMD01003011    JAA98579.1    DS231898    EDS44600.1    BT001619    AAN71374.1    KK852425    KDR24163.1    GFDL01008958    JAV26087.1    GFDL01008978    JAV26067.1    JRES01001160    KNC24986.1    AXCN02000138    JQ042683    AEZ67826.1    CH933806    EDW14374.1    KRG00981.1    KB630144    ERL83427.1    APGK01036258    KB740937    ENN77775.1    GBYB01009424    JAG79191.1    BT127791    KB631226    AEE62753.1    ERL84168.1    ATLV01020511    KE525302    KFB45362.1    GBYB01009425    JAG79192.1    GAKP01018578    JAC40374.1    EZ424127    ADD20403.1    CH954181    EDV47928.1    CH902617    KPU79269.1    GAKP01018580    JAC40372.1    CVRI01000040    CRK94888.1    EDV41635.1    GBRD01011179    GDHC01016869    JAG54645.1    JAQ01760.1    JXJN01010490    GDHF01033247    JAI19067.1    GDHF01026894    JAI25420.1    GDHF01033196    JAI19118.1   

Proteomes

UP000005204    UP000053240    UP000218220    UP000053268    UP000007266    UP000009046    + More
UP000235965    UP000095301    UP000092461    UP000192223    UP000008820    UP000008792    UP000092553    UP000007798    UP000095300    UP000000673    UP000069940    UP000249989    UP000069272    UP000268350    UP000000803    UP000001070    UP000002282    UP000001819    UP000075883    UP000075884    UP000075880    UP000002320    UP000027135    UP000037069    UP000075901    UP000075886    UP000076408    UP000091820    UP000009192    UP000030742    UP000019118    UP000030765    UP000075920    UP000075881    UP000078200    UP000092445    UP000008711    UP000007801    UP000183832    UP000192221    UP000075885    UP000092443    UP000092460    UP000075903    UP000076407   

PRIDE

H9J5R2    Q9NFN9    Q9VNF8    Q8IGT0   

Pfam

PF08033   Sec23_BS        + More
PF00626   Gelsolin
PF04811   Sec23_trunk
PF04810   zf-Sec23_Sec24
PF04815   Sec23_helical

Interpro

IPR029006   ADF-H/Gelsolin-like_dom_sf        + More
IPR037550   Sec23_C       
IPR036174   Znf_Sec23_Sec24_sf       
IPR007123   Gelsolin-like_dom       
IPR037364   Sec23       
IPR036180   Gelsolin-like_dom_sf       
IPR006900   Sec23/24_helical_dom       
IPR012990   Sec23_24_beta_S       
IPR006896   Sec23/24_trunk_dom       
IPR036465   vWFA_dom_sf       
IPR036175   Sec23/24_helical_dom_sf       
IPR006895   Znf_Sec23_Sec24       

SUPFAM

SSF82919   SSF82919        + More
SSF81811   SSF81811       
SSF82754   SSF82754       
SSF53300   SSF53300       

Gene 3D

3.40.20.10     3.40.50.410    

CDD

cd11287  Sec23_C

ProteinModelPortal

H9J5R2   A0A2W1BXB0   A0A0N1I9D7   A0A2A4JPS7   A0A194PFX2   A0A1E1WGU3   + More
S4PSB0   D6WT99   A0A139WFB6   A0A2D1QUK3   A0A336MH18   A0A336MWW3   E0VYI1   U5EZI3   A0A2J7RPU3   A0A2J7RPV0   A0A1I8NGE3   A0A1I8NGC8   A0A1B6D2P7   A0A1B0CEZ0   A0A1B6D2Y3   A0A1W4WSA3   A0A1W4WG52   Q171Y9   A0A0Q9W0Y2   A0A0M4F682   A0A0Q9X5J3   A0A2M3YZ76   B4N9Z7   A0A1Y1K6B6   B4M3T5   A0A2M4A1T9   A0A2M4BER3   Q171Z0   A0A1I8Q6S2   A0A0K8TSA6   W5JNW3   A0A0Q9WD23   A0A1I8Q6M9   A0A2M4A1T5   A0A2M4BEN3   A0A182GSS4   A0A182FNT3   Q9NFN9   A0A3B0KMV7   A0A0B4K5Z8   B4JEV8   Q9VNF8   A0A0B4K6T4   A0A3B0KHK3   A0A0R1E5B3   B4PUW0   B5DXU4   I5ANM9   A0A3B0KRP7   A0A182M2K5   A0A182NLI1   A0A0T6BAD1   T1DFV5   A0A182IPZ5   B0WDJ1   Q8IGT0   A0A067RMD5   A0A1Q3FEV9   A0A1Q3FET2   A0A0L0BYD7   A0A182SSY1   A0A182Q724   H6WAQ8   A0A1A9W888   B4K8H5   A0A0Q9WZ29   U4TRT6   N6U7X9   A0A0C9R009   J3JX23   A0A084W568   A0A0C9RM98   A0A182VRR7   A0A182JXQ9   A0A1A9UN52   A0A1B0AA87   A0A034VCZ7   D3TRS5   B3P2H8   A0A0P8YCW4   A0A034VE33   A0A1J1I3K2   A0A1W4UWI1   B3LWP1   A0A182NZD3   A0A0K8SP95   A0A1W4UJI9   A0A1A9XHP0   A0A1B0B9K9   A0A0K8TX82   A0A0K8UGG8   A0A0K8TXV2   A0A182VAG9   A0A182WSX3  

PDB

2NUT     E-value=0,     Score=2974

KEGG

101743064    K14006 protein transport protein SEC23 | (RefSeq) protein transport protein Sec23A

PATHWAY

04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)

GO

GO:0000139   GO:0030127   GO:0090114   GO:0005789   GO:0006886   GO:0008270   GO:0090110   GO:0005096   GO:0070971   GO:0034394   GO:0048081   GO:0035149   GO:0016203   GO:0007030   GO:0030011   GO:0071711   GO:0005795   GO:0050775   GO:0007029   GO:0035293   GO:0003331   GO:0072659   GO:0008360   GO:0022409   GO:0008363   GO:0030134   GO:0040003   GO:0003400   GO:0043547   GO:0005783   GO:0016021   GO:0006888   GO:0005515   GO:0003676   GO:0007154   GO:0016020   GO:0005112   GO:0015930  

PANTHER

PTHR11141  

Subcellular location

Cytoplasmic vesicle  
COPII-coated vesicle membrane  
Endoplasmic reticulum membrane  

Length:

715

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0767000000000001

Exp number, first 60 AAs:

0.00068

Total prob of N-in:

0.00305

outside

1  -  715

 

 

Pi

175.027143

Theta

206.13934

Tajima's D

0.11337

CLR

1.114769

CSRT

0.399530023498825

Interpretation

Uncertain