Gene

KWMTBOMO15031

Pre Gene Modal

BGIBMGA004804

Annotation

PREDICTED:_insecticyanin-A-like_[Amyelois_transitella]

Location

Bomo_Chr25(+):3236828-3239586      View in EpiBrowser

Full name

Apolipoprotein D      

Location in the cell

PlasmaMembrane   Reliability : 2.132

CDS

ATGAATGTAGTAAACTTATTTCTCGTCGTGGTGCTAGTGAATACCAGTGGAGGGCAGGTTCTACAGTTCGGGCAATGCCCTGAAGTGGAAACGATGGAGTATTTCGATTTGGTCCGATTTTTAGGCAGATGGTTCGAGATTGAAAGATTCCCCGCTTGGTTCGAGGATAAAGGGCACTGCGCTTACAAACGTTTTCAATACTGCAACAGGAAAGTGGAGATCGAACAAGTTTTTATACGAGACGGGATCCGATTCATTATCCACCGGAACAGCTCTTACAACCCTGGCGACGAAGCTATATTTGATATCCAGCCTAGCAATATCGATCCCGTTGGAATTCCACTCTCAGTTATATCAACAGATTACAATAACTACGCGATATTGTTCGGCTGCAAATTCAATGTTCAAATGGACATGAAATACATTCTAGCTTGGATCTTATCACGAGAGCAGTCTCTACCTCCCGAAGTGCTGAATGAAACACGAAGGAAACTGAACTCTATACCGTTTGCCAACGCCGCGTATTTGATGCCAGTGAACCACACCGAATATAACTGCAACTATCATTGGACAGCTCACATACAGTCAGTTTATAAAACCGTCGATGAAAATTAA

Protein

MNVVNLFLVVVLVNTSGGQVLQFGQCPEVETMEYFDLVRFLGRWFEIERFPAWFEDKGHCAYKRFQYCNRKVEIEQVFIRDGIRFIIHRNSSYNPGDEAIFDIQPSNIDPVGIPLSVISTDYNNYAILFGCKFNVQMDMKYILAWILSREQSLPPEVLNETRRKLNSIPFANAAYLMPVNHTEYNCNYHWTAHIQSVYKTVDEN

Subunit

Homodimer.
Homodimer. In plasma, also exists as a disulfide-linked heterodimer with APOA2.

Miscellaneous

APOD is primarily localized in HDL (60-65%), with most of the remainder in VHDL and only trace amounts in VLDL and LDL.

Similarity

Belongs to the calycin superfamily. Lipocalin family.

Keywords

3D-structure   Complete proteome   Direct protein sequencing   Disulfide bond   Glycoprotein   Lipid-binding   Polymorphism   Pyrrolidone carboxylic acid   Reference proteome   Secreted   Signal   Transport  

Feature

chain  Apolipoprotein D
sequence variant  In dbSNP:rs5952.

Uniprot

H9J5L4   A0A2H1VRJ6   A0A2W1BRY3   A0A2A4JUE3   A0A194RID2   A0A194PGK5   + More
A0A0L7KYF1   A0A3Q1CWP9   A0A3P8U4S6   H2SBW8   A0A3B4A3N8   A0A3B5A893   K7G6U9   A0A315W2H7   A0A3Q2D080   A0A3B4UF30   A0A3B3DF18   M4ATN9   A0A3P8PHX2   A0A3Q4MMR4   G3NP26   A0A2U9BID1   A0A3B4FN67   G3PXW5   A0A210PTS9   A0A3B4FNS2   G3QHM6   A0A3B5MND9   I3KQQ8   A0A2R9AZL2   H2R7U9   A0A3Q3X7M7   A0A2I2YU70   P05090   A0A3B3X9L5   A0A2R9B0W6   G1RAG0   A0A2I3STN5   A0A3P9H6R0   C9JF17   A0A0S7MDZ3   A0A3P9DEB8   A0A3B4FLI0   A0A2U9BJ84   A0A2I3I0L6   H2MUK0   A0A3Q3F1K5   A0A2J8WIB1   A0A3B3H6U8   Q95P97   A0A3Q3FD39   A0A3Q3FD57   A0A2P6L7P3   A0A3B3VGE1   A0A3P9K4I5   A0A087XJD9   H2MUJ9   Q8T118   A0A2J8WID0   A0A3B3DF20   A0A3B3YMF2   A0A3P8W739   A0A3Q4GZL5   A0A3B4FPS1   A0A3B4X9M0   A0A2K5QQY3   A0A3Q0RKG1   I3NB19   H2PCF2   A0A3B4UFP1   A0A1A8VAG0   A0A146XZX9   M4ATM9   A0A3B5MUT8   A0A3L8D4I0   A0A3Q3XJW8   A0A146N9B8   A0A3B3X9D5   A0A3B3VE73   A0A3Q2QH17   A0A087XJL0   Q00629   A0A3P9K5L3   I4DII3   A0A147ARL5   A0A3Q2D0T8   A0A3Q3MA71   A0A2K6TAT2   A0A3P9PEZ3   A0A3Q0CSM2   A0A3Q3X7P6   A0A3B4UH23   A0A3P9K5M3   A0A2K6TAS6   A0A3Q2P803   A0A2R8MFE7   A0A3Q3XPV3   A0A3Q0R232   I4DLT4  

Pubmed

19121390    28756777    26354079    26227816    21551351    25463417    + More
17381049    29703783    29451363    23542700    25186727    28812685    22398555    22722832    16136131    3453108    2439269    14702039    15489334    7918467    8549691    2244881    14760718    16335952    19159218    19139490    19838169    22171320    24275569    2083249    7613477    10391209    17554307    16641997    24487278    30249741    1572353    22651552    26319212   

EMBL

BABH01025084    ODYU01003843    SOQ43102.1    KZ149918    PZC77808.1    NWSH01000611    + More
PCG75318.1    KQ460205    KPJ17085.1    KQ459604    KPI92163.1    JTDY01004480    KOB68096.1    AGCU01131987    AGCU01131988    NHOQ01000466    PWA30007.1    CP026249    AWP03818.1    NEDP02005506    OWF39856.1    CABD030026414    AERX01019766    AJFE02022441    AJFE02022442    AACZ04067380    GABC01002755    GABD01010538    GABE01008228    NBAG03000439    JAA08583.1    JAA22562.1    JAA36511.1    PNI24130.1    J02611    M16696    BT019860    BT019861    CR456838    CR541773    AK312090    CH471052    BC007402    S80440    ADFV01124490    PNI24132.1    AC069213    GBYX01069461    JAO99769.1    AWP03819.1    AWP03820.1    NDHI03003390    PNJ69520.1    AB050439    BAB47155.1    MWRG01001164    PRD34593.1    AYCK01009881    AB080223    BAB85482.1    PNJ69522.1    AGTP01111365    AGTP01111366    AGTP01111367    AGTP01111368    ABGA01224108    ABGA01224109    HAEJ01016135    SBS56592.1    GCES01038793    JAR47530.1    QOIP01000014    RLU15041.1    GCES01157899    JAQ28423.1    X64714    CAA45969.1    AK401101    BAM17723.1    KPI92171.1    GCES01005581    JAR80742.1    AK402252    BAM18874.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000037510    UP000257160    + More
UP000265080    UP000005226    UP000261520    UP000261400    UP000007267    UP000265020    UP000261420    UP000261560    UP000002852    UP000265100    UP000261580    UP000007635    UP000246464    UP000261460    UP000242188    UP000001519    UP000261380    UP000005207    UP000240080    UP000002277    UP000261620    UP000005640    UP000261480    UP000001073    UP000265200    UP000265160    UP000001038    UP000261660    UP000261500    UP000265180    UP000028760    UP000265120    UP000261360    UP000233040    UP000261340    UP000005215    UP000001595    UP000279307    UP000265000    UP000233220    UP000242638    UP000189706    UP000008225   

PRIDE

H9J5L4    P05090    C9JF17    Q95P97    H2PCF2   

Pfam

PF00061   Lipocalin        + More
PF08212   Lipocalin_2

Interpro

IPR003057   Invtbrt_color        + More
IPR012674   Calycin       
IPR022271   Lipocalin_ApoD       
IPR000566   Lipocln_cytosolic_FA-bd_dom       
IPR022272   Lipocalin_CS       
IPR002969   ApolipopD       
IPR026222   ApoD_vertbrte       

SUPFAM

SSF50814   SSF50814       

Gene 3D

2.40.128.20    

ProteinModelPortal

H9J5L4   A0A2H1VRJ6   A0A2W1BRY3   A0A2A4JUE3   A0A194RID2   A0A194PGK5   + More
A0A0L7KYF1   A0A3Q1CWP9   A0A3P8U4S6   H2SBW8   A0A3B4A3N8   A0A3B5A893   K7G6U9   A0A315W2H7   A0A3Q2D080   A0A3B4UF30   A0A3B3DF18   M4ATN9   A0A3P8PHX2   A0A3Q4MMR4   G3NP26   A0A2U9BID1   A0A3B4FN67   G3PXW5   A0A210PTS9   A0A3B4FNS2   G3QHM6   A0A3B5MND9   I3KQQ8   A0A2R9AZL2   H2R7U9   A0A3Q3X7M7   A0A2I2YU70   P05090   A0A3B3X9L5   A0A2R9B0W6   G1RAG0   A0A2I3STN5   A0A3P9H6R0   C9JF17   A0A0S7MDZ3   A0A3P9DEB8   A0A3B4FLI0   A0A2U9BJ84   A0A2I3I0L6   H2MUK0   A0A3Q3F1K5   A0A2J8WIB1   A0A3B3H6U8   Q95P97   A0A3Q3FD39   A0A3Q3FD57   A0A2P6L7P3   A0A3B3VGE1   A0A3P9K4I5   A0A087XJD9   H2MUJ9   Q8T118   A0A2J8WID0   A0A3B3DF20   A0A3B3YMF2   A0A3P8W739   A0A3Q4GZL5   A0A3B4FPS1   A0A3B4X9M0   A0A2K5QQY3   A0A3Q0RKG1   I3NB19   H2PCF2   A0A3B4UFP1   A0A1A8VAG0   A0A146XZX9   M4ATM9   A0A3B5MUT8   A0A3L8D4I0   A0A3Q3XJW8   A0A146N9B8   A0A3B3X9D5   A0A3B3VE73   A0A3Q2QH17   A0A087XJL0   Q00629   A0A3P9K5L3   I4DII3   A0A147ARL5   A0A3Q2D0T8   A0A3Q3MA71   A0A2K6TAT2   A0A3P9PEZ3   A0A3Q0CSM2   A0A3Q3X7P6   A0A3B4UH23   A0A3P9K5M3   A0A2K6TAS6   A0A3Q2P803   A0A2R8MFE7   A0A3Q3XPV3   A0A3Q0R232   I4DLT4  

PDB

2HZR     E-value=2.30783e-13,     Score=179

KEGG

101745459    K03098 apolipoprotein D and lipocalin family protein | (RefSeq) apolipoprotein D-like

GO

GO:0031409   GO:0016021   GO:0006869   GO:0007568   GO:0008289   GO:2000098   GO:0005615   GO:0071638   GO:2000405   GO:0000302   GO:0060588   GO:0010642   GO:0048471   GO:0006629   GO:1900016   GO:0042308   GO:0051895   GO:0048662   GO:0006006   GO:0015485   GO:0030425   GO:0005783   GO:0042246   GO:0042493   GO:0048678   GO:0005737   GO:0043025   GO:0007420   GO:0014012   GO:0022626   GO:0001525   GO:0005319   GO:0070062   GO:0005576   GO:0006508   GO:0008270   GO:0004180   GO:0005515   GO:0003676   GO:0007154   GO:0016020   GO:0005112   GO:0015930  

Subcellular location

Secreted  

SignalP

Position:   1 - 18,         Likelihood:  0.971118

 

 

Length:

204

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.26035

Exp number, first 60 AAs:

1.19191

Total prob of N-in:

0.08018

outside

1  -  204

 

 

Pi

304.747234

Theta

183.979228

Tajima's D

2.330703

CLR

0.365394

CSRT

0.930303484825759

Interpretation

Uncertain