Gene

KWMTBOMO15005

Pre Gene Modal

BGIBMGA004794

Annotation

PREDICTED:_sodium/calcium_exchanger_2_[Bombyx_mori]

Location

Bomo_Chr25(+):2217362-2219306      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 1.477

CDS

ATGCGGCCCGCGCTCGCCGCGATCGCGGCCTGCTGCGTGGCGGCACGCGCCGAGCCCCCCTCGCGCCTCGCACCCCTCAACACCACCCCCCAGCACGTTCTCCAGTGCTCCGATGGCCTCGTGCTGCCCGCCTGGAGGCCTCTCGAAGATGTCCCCACTTACCAAATCGCGATACGCGGCTTCGTCTACTTTCTTGCGCTCATGTACCTCTTCATTGGGGTGTCTATTGTCTCTGATCGGTTTATGGCCGCCATAGAAGTTATCACGTCCAGAGAAAAAGAGGTGCGCGTGCGGCGCAACGGCAGTGAACAGATCATAGTTGTTCGAGTCTGGAATGAGACCGTTGCCAATTTGACGTTGATGGCTCTCGGATCGAGTGCACCTGAGATACTCTTATCAGTAATCGAGATAGCCGGAAAGAATTTCGAAGCCGGAGATTTGGGCCCCGGCACCATCGTGGGTTCTGCTGCCTATAATCTTTTTGTCATAATCGCCATCTGCGTTGTGGTGATCCCGGATGGAGAAGTGCGCAAGATAAAACATCTTCGAGTATTCTTAGTGACCGCGACTTGGTCGATATTCGCCTATGTATGGCTATATATGATTTTGGCGGTTATATCACCAAGTGAAGTCGAAGTATGGGAGGGTGCGGTCACTTTCTTGTTCTTCCCGGCGACTGTCATGACAGCTTATATTGCTGATCGTCGCCTGCTCGTCTATAAATATCTCAAGAAAGGCTACAGAGTGAACGAGAGAGGCGTCATAGTTGAAGCCGAGGGTGACGGTTCTCTAGAGATGGCGCTGAAGCCTGGCGGAGACGATTTTATGTCTGATGACGACGAAGGCCGAGAACTAGAGAAGTCACGGAAAGAATACGTATCAGTTCTCCGCGAACTGAGAAGACAGCATCCAGACGAAGATTTAGAAACCGTTGAGAGAATGGCTTTGGAAACGTTAATGGCAAGTGGTCCTAAATCACGAGCGTTCTACAGAGTTGCGGCGACTCGTAAAATGACCGGTGGCGGTGATTTTTCGCGGAAAATCTCCGAGAGGGCCCAGAGCGATTTGAGCGAGGTAAAAGCGGAGTTACAGAGACGAGATTCTGGTTCGGCGTCAATTGAGCCGCGCGGTCCAAACGTTCGTTTCGATCCTGACCACTACACCGTCATGGAGAACTGCGGCTCGTTCGAAGTTCGAGTTGTAAGGGCTGGAGATCTTAACGGTGACGTCACTGTTCAGTACACCACCGAAGATGGGACCGCTGAAGCTGGCTCAGATTATGTGACCGCTCAAGGATTATTGCATTTCAAACACGGAGAAACGGAGAAGACGTTTAGAGTTCAAGTCATTGATGATGATGTTTTTGAGGAAGATGAGCATTTTTACGTTCGTCTGTCATCGCCAAAGGGCGCTTCCTTGGCTTCTCCGTCTACCGCTACTGTAGTGATACTCGACGATGACCACTCCGGCGTATTTTCGTTCCCTCAACGCGATTTCGAGCTGACAGAGTCCGTTGGGACATATGATCTGAAGGTGGTGAGGACAGCTGGCGCCCGCGGGAAGGTCAGGATTCCTTACTGGACCGAGGACGGCACAGCTAAGGGAGGCGCTCAGTACGAGATTGCACAAGGCCACATCTTCTTCGAAAACAACGAGACCGAGTAA

Protein

MRPALAAIAACCVAARAEPPSRLAPLNTTPQHVLQCSDGLVLPAWRPLEDVPTYQIAIRGFVYFLALMYLFIGVSIVSDRFMAAIEVITSREKEVRVRRNGSEQIIVVRVWNETVANLTLMALGSSAPEILLSVIEIAGKNFEAGDLGPGTIVGSAAYNLFVIIAICVVVIPDGEVRKIKHLRVFLVTATWSIFAYVWLYMILAVISPSEVEVWEGAVTFLFFPATVMTAYIADRRLLVYKYLKKGYRVNERGVIVEAEGDGSLEMALKPGGDDFMSDDDEGRELEKSRKEYVSVLRELRRQHPDEDLETVERMALETLMASGPKSRAFYRVAATRKMTGGGDFSRKISERAQSDLSEVKAELQRRDSGSASIEPRGPNVRFDPDHYTVMENCGSFEVRVVRAGDLNGDVTVQYTTEDGTAEAGSDYVTAQGLLHFKHGETEKTFRVQVIDDDVFEEDEHFYVRLSSPKGASLASPSTATVVILDDDHSGVFSFPQRDFELTESVGTYDLKVVRTAGARGKVRIPYWTEDGTAKGGAQYEIAQGHIFFENNETE

Similarity

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.

Uniprot

H9J5K4   A0A0L7L0T9   A0A2W1BVS7   A0A2A4K8J9   A0A2H1VYJ5   A0A194PLS1   + More
A0A194RHJ1   A0A182JJZ5   A0A182FR14   A0A084VDP7   A0A2M4D0D9   W5JPW4   A0A182LUI7   A0A1W4W6T8   A0A1W4WH66   A0A182LGD6   A0A182PSN5   A0A182XHL9   A0A182N736   A0A1Q3FVJ1   A0A182TGL3   A0A182HTS1   A0A182RQ22   A0A1Y1NCB8   A0A1Q3FVG2   A0A182VKI1   B0WFC7   T1PL58   A0A1I8M5B8   A0A182XW65   T1PCS8   A0A1Y1NF08   A0A182QRM5   Q7QCY1   A0A182SRE0   A0A340TBD3   A0A1I8NM23   A0A182GWS3   A0A0L0C7G8   A0A088AB77   Q16I58   A0A1A9VQX7   A0A336MKN7   A0A336KYC1   A0A2P8YJ54   A0A1B0GG32   A0A1B0BG46   A0A1A9YLF2   A0A1A9ZK36   D6WRH9   A0A1A9WFS1   A0A034VVP4   A0A034VUX1   A0A067RIB9   A0A034VRI2   K7J313   K7J312   A0A034VVP9   A0A0K8V717   A0A0K8V0D8   A0A0A1WL41   E2BQW9   A0A1B0F0A8   A0A0C9QG73   A0A154P3C3   A0A0L7QTV0   A0A151JX34   E2A905   A0A195D775   A0A026WFF4   A0A3L8DJC3   A0A151J7Z1   A0A158NME2   E9J4G4   A0A151I3A1   W8AQ93   W8AL91   A0A1B0CQJ3   A0A1J1IYH5   A0A151WVJ6   N6TD33   E9GI59   F4X5T9   A0A0Q9WT62   A0A3B0K369   B4NBR4   A0A3B0K4Y3   A0A0Q9X3H3   B4R1P3   Q24413   A0A0B4LHD7   Q9VDG5   A0A0B4K6R7   A0A0B4K6E2   A0A0B4K6A6   A0A0B4K790   A0A0R1E453   A0A0R1E1M0   B4PQ94   A0A1W4VYS2  

Pubmed

19121390    26227816    28756777    26354079    24438588    20920257    + More
23761445    20966253    28004739    25315136    25244985    12364791    14747013    17210077    26483478    26108605    17510324    29403074    18362917    19820115    25348373    24845553    20075255    25830018    20798317    24508170    30249741    21347285    21282665    24495485    23537049    21292972    21719571    17994087    8659862    9252464    19361442    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    22000518    26109357    26109356    17550304   

EMBL

BABH01025184    JTDY01003719    KOB69097.1    KZ149903    PZC78441.1    NWSH01000067    + More
PCG80000.1    ODYU01005227    SOQ45878.1    KQ459604    KPI92055.1    KQ460205    KPJ16790.1    ATLV01011641    ATLV01011642    ATLV01011643    ATLV01011644    ATLV01011645    ATLV01011646    ATLV01011647    ATLV01011648    KE524705    KFB36091.1    GGFL01006763    MBW70941.1    ADMH02000448    ETN66432.1    AXCM01011352    GFDL01003612    JAV31433.1    APCN01000583    GEZM01009898    JAV94235.1    GFDL01003613    JAV31432.1    DS231916    EDS26144.1    KA649454    AFP64083.1    KA645935    AFP60564.1    GEZM01009896    JAV94237.1    AXCN02000324    AAAB01008859    EAA07757.5    JXUM01094026    KQ564097    KXJ72802.1    JRES01000809    KNC28220.1    CH478105    EAT33944.1    UFQS01001222    UFQT01001222    SSX09826.1    SSX29549.1    SSX09827.1    SSX29550.1    PYGN01000557    PSN44272.1    CCAG010016049    CCAG010016050    CCAG010016051    CCAG010016052    CCAG010016053    CCAG010016054    CCAG010016055    CCAG010016056    CCAG010016057    CCAG010016058    JXJN01013744    JXJN01026459    KQ971351    EFA06448.1    GAKP01013037    JAC45915.1    GAKP01013040    JAC45912.1    KK852489    KDR22763.1    GAKP01013031    JAC45921.1    GAKP01013032    JAC45920.1    GDHF01026480    GDHF01025859    GDHF01017628    GDHF01003041    JAI25834.1    JAI26455.1    JAI34686.1    JAI49273.1    GDHF01020071    JAI32243.1    GBXI01015169    JAC99122.1    GL449813    EFN81923.1    AJVK01017886    GBYB01002434    JAG72201.1    KQ434809    KZC06347.1    KQ414741    KOC61984.1    KQ981655    KYN38614.1    GL437703    EFN70104.1    KQ976750    KYN08707.1    KK107238    EZA54840.1    QOIP01000007    RLU20273.1    KQ979602    KYN20513.1    ADTU01020397    ADTU01020398    ADTU01020399    ADTU01020400    ADTU01020401    ADTU01020402    ADTU01020403    ADTU01020404    ADTU01020405    GL768105    EFZ12237.1    KQ976507    KYM82810.1    GAMC01019902    JAB86653.1    GAMC01019903    JAB86652.1    AJWK01023677    CVRI01000064    CRL05207.1    KQ982701    KYQ51930.1    APGK01035308    KB740923    KB632333    ENN78254.1    ERL92685.1    GL732546    EFX80619.1    GL888742    EGI58179.1    CH964232    KRF99413.1    OUUW01000013    SPP87763.1    EDW81228.1    SPP87762.1    KRF99414.1    CM000364    EDX12152.1    L39835    AAB50166.1    AE014297    AHN57433.1    AY118680    BT011420    AAF55829.1    AAM50540.1    AAN13844.1    AAN13845.1    AAR96212.1    AFH06530.1    AFH06533.1    AFH06532.1    AFH06531.1    CM000160    KRK02992.1    KRK02995.1    KRK02991.1    EDW96203.2    KRK02989.1    KRK02993.1    KRK02994.1    KRK02996.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000053268    UP000053240    UP000075880    + More
UP000069272    UP000030765    UP000000673    UP000075883    UP000192223    UP000075882    UP000075885    UP000076407    UP000075884    UP000075902    UP000075840    UP000075900    UP000075903    UP000002320    UP000095301    UP000076408    UP000075886    UP000007062    UP000075901    UP000075920    UP000095300    UP000069940    UP000249989    UP000037069    UP000005203    UP000008820    UP000078200    UP000245037    UP000092444    UP000092460    UP000092443    UP000092445    UP000007266    UP000091820    UP000027135    UP000002358    UP000008237    UP000092462    UP000076502    UP000053825    UP000078541    UP000000311    UP000078542    UP000053097    UP000279307    UP000078492    UP000005205    UP000078540    UP000092461    UP000183832    UP000075809    UP000019118    UP000030742    UP000000305    UP000007755    UP000007798    UP000268350    UP000000304    UP000000803    UP000002282    UP000192221   

PRIDE

H9J5K4    Q24413    Q9VDG5   

Pfam

PF01699   Na_Ca_ex        + More
PF16494   Na_Ca_ex_C
PF03160   Calx-beta

Interpro

IPR004837   NaCa_Exmemb        + More
IPR038081   CalX-like_sf       
IPR004836   Na_Ca_Ex       
IPR003644   Calx_beta       
IPR032452   Na_Ca_Ex_C-exten       

SUPFAM

SSF141072   SSF141072       

Gene 3D

2.60.40.2030    

ProteinModelPortal

H9J5K4   A0A0L7L0T9   A0A2W1BVS7   A0A2A4K8J9   A0A2H1VYJ5   A0A194PLS1   + More
A0A194RHJ1   A0A182JJZ5   A0A182FR14   A0A084VDP7   A0A2M4D0D9   W5JPW4   A0A182LUI7   A0A1W4W6T8   A0A1W4WH66   A0A182LGD6   A0A182PSN5   A0A182XHL9   A0A182N736   A0A1Q3FVJ1   A0A182TGL3   A0A182HTS1   A0A182RQ22   A0A1Y1NCB8   A0A1Q3FVG2   A0A182VKI1   B0WFC7   T1PL58   A0A1I8M5B8   A0A182XW65   T1PCS8   A0A1Y1NF08   A0A182QRM5   Q7QCY1   A0A182SRE0   A0A340TBD3   A0A1I8NM23   A0A182GWS3   A0A0L0C7G8   A0A088AB77   Q16I58   A0A1A9VQX7   A0A336MKN7   A0A336KYC1   A0A2P8YJ54   A0A1B0GG32   A0A1B0BG46   A0A1A9YLF2   A0A1A9ZK36   D6WRH9   A0A1A9WFS1   A0A034VVP4   A0A034VUX1   A0A067RIB9   A0A034VRI2   K7J313   K7J312   A0A034VVP9   A0A0K8V717   A0A0K8V0D8   A0A0A1WL41   E2BQW9   A0A1B0F0A8   A0A0C9QG73   A0A154P3C3   A0A0L7QTV0   A0A151JX34   E2A905   A0A195D775   A0A026WFF4   A0A3L8DJC3   A0A151J7Z1   A0A158NME2   E9J4G4   A0A151I3A1   W8AQ93   W8AL91   A0A1B0CQJ3   A0A1J1IYH5   A0A151WVJ6   N6TD33   E9GI59   F4X5T9   A0A0Q9WT62   A0A3B0K369   B4NBR4   A0A3B0K4Y3   A0A0Q9X3H3   B4R1P3   Q24413   A0A0B4LHD7   Q9VDG5   A0A0B4K6R7   A0A0B4K6E2   A0A0B4K6A6   A0A0B4K790   A0A0R1E453   A0A0R1E1M0   B4PQ94   A0A1W4VYS2  

PDB

3RB7     E-value=1.34009e-54,     Score=540

KEGG

101741376    K05849 solute carrier family 8 (sodium/calcium exchanger) | (RefSeq) sodium/calcium exchanger 2

GO

GO:0005432   GO:0016021   GO:0007154   GO:0005509   GO:0034976   GO:0050884   GO:0007602   GO:0006816   GO:0016020   GO:0003676   GO:0005112   GO:0015930   GO:0055085  

SignalP

Position:   1 - 17,         Likelihood:  0.951447

 

 

Length:

554

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

100.2029

Exp number, first 60 AAs:

3.99661

Total prob of N-in:

0.44712

inside

1  -  55

TMhelix

56  -  78

outside

79  -  148

TMhelix

149  -  171

inside

172  -  183

TMhelix

184  -  206

outside

207  -  215

TMhelix

216  -  238

inside

239  -  554

 

 

Pi

263.212695

Theta

236.149198

Tajima's D

0.28211

CLR

0

CSRT

0.451977401129944

Interpretation

Uncertain