Gene

KWMTBOMO14945  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000808

Annotation

PREDICTED:_5'-3'_exoribonuclease_2_homolog_[Bombyx_mori]

Location

Bomo_Chr25(+):891103-896457      View in EpiBrowser

Full name

5'-3' exoribonuclease       + More
5'-3' exoribonuclease 2 homolog      

Alternative Name

Ribonucleic acid-trafficking protein 1

Location in the cell

Cytoplasmic   Reliability : 2.274 Nuclear   Reliability : 2.132

CDS

ATGGGAGTTCCAGCGTTCTTCCGCTGGCTCAGCCGAAAATATCCAAGTGTAATAGTGGAATGTGTTGAACAAAAGCCAACCGACGTAGATGGCCAGTTAGTATATGTAGATTCCTCCCTCCCTAATCCAAATGGAGTGGAGTTTGACAATTTATACCTGGACATGAATGGTATCATCCATCCATGCACCCATCCCGAGGATAAACCAGCACCAAAAGATGAGGATGAGATGATGGTTGCCATCTTTGAATGCATTGACAGACTTTTTCGTATTGTGAGGCCTAGGAAACTGTTGTATATGGCTATAGATGGAGTGGCTCCAAGAGCTAAAATGAACCAGCAACGTTCTCGACGTTTCCGTGCGTCCAAAGAAACCCAAGAGAAGATTGAGGAAGTGGCTCGCATCCGTAATGAACTTCAGGCTAAAGGAGCATACTTACCACCAGAGAGGCCTAAGGAAGCTCACTTTGATTCTAATTGTATCACACCGGGGACACCGTTCATGGACAGACTGAGCAAGTGTCTGCATTATTACATACATGACAGATTAAATAATGACCCCGGATGGAAGGGCATTAAGGTTATATTATCTGATGCAAATGTTCCTGGGGAAGGAGAACATAAGATTATGGACTACATTAGGAGACAAAGAGCGCAACCAGACCACGACCCAAACACTCAGCATGTTTTGTGCGGTGCTGATGCTGATTTAATCATGCTGGGTCTGGCCACTCACGAGCCAAACTTCACTATCATCCGTGAGGAATTCAAGCCTAATAAACCGAGACCCTGTGATGTTTGCGGGCAACTTGGTCACGAAATGAAGGAATGCACGGGAACGAACCCGGACGCGTCAGTCGTTCGTTCCGATCCGGCGTTCGGGAACCAGGACAACTTTATATTCGTCCGGCTCAGCGTGCTCCGGGAGTATTTGGAGAGAGAGCTGCAGATGCCGAACCTTCCGTTTCCGTACGACTTCGAGCGCGCCCTGGACGACTGGGTGTTCATGTGCTTCTTCGTGGGGAACGACTTCCTGCCGCACCTGCCCAGCCTCGAGATCCGCGAGGGGGCCGTGGACAGGCTGGTCAACTTGTACAAGAAATGCGTTTACAAGACCAAGGGCTGGATAACCGATTCGGGAGATGTGGAGCTGGACCGCGTGCAGGTCATAATGACGGAGCTGGGTCACGTGGAGGACGAGATATTCAAGCGAAGGCATCAGAACGAGCTGAGCTTCAGAGCGAGGGACAAAGCCAAGAAGAAACAGCAGCGGGTCAACTTCGAGCTGCTGGAGAACACGCAGTTTGCCCCGGAGGTAGGCGACGGTAACGTTAGGAATGGCGGTCACGTGTGA

Protein

MGVPAFFRWLSRKYPSVIVECVEQKPTDVDGQLVYVDSSLPNPNGVEFDNLYLDMNGIIHPCTHPEDKPAPKDEDEMMVAIFECIDRLFRIVRPRKLLYMAIDGVAPRAKMNQQRSRRFRASKETQEKIEEVARIRNELQAKGAYLPPERPKEAHFDSNCITPGTPFMDRLSKCLHYYIHDRLNNDPGWKGIKVILSDANVPGEGEHKIMDYIRRQRAQPDHDPNTQHVLCGADADLIMLGLATHEPNFTIIREEFKPNKPRPCDVCGQLGHEMKECTGTNPDASVVRSDPAFGNQDNFIFVRLSVLREYLERELQMPNLPFPYDFERALDDWVFMCFFVGNDFLPHLPSLEIREGAVDRLVNLYKKCVYKTKGWITDSGDVELDRVQVIMTELGHVEDEIFKRRHQNELSFRARDKAKKKQQRVNFELLENTQFAPEVGDGNVRNGGHV

Description

Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.
Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II (By similarity).

Subunit

Does not interact with cuff.

Similarity

Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.

Keywords

Complete proteome   Exonuclease   Hydrolase   Metal-binding   mRNA processing   Nuclease   Nucleus   Phosphoprotein   Reference proteome   Transcription   Transcription regulation   Transcription termination   Zinc   Zinc-finger  

Feature

chain  5'-3' exoribonuclease 2 homolog

Uniprot

A0A1E1VXM3   A0A2H1WES3   A0A3S2P1B9   A0A212EYH4   A0A194RGT2   A0A194PHC4   + More
A0A0C9RJG1   A0A154P516   A0A1W4WK74   A0A1W4WK62   E2BLM1   A0A195DG40   A0A232F0M1   A0A0L7R1M4   A0A0M8ZVB7   A0A158NKN8   A0A087ZZT3   A0A195BLW1   V9ILF4   A0A2A3ER15   A0A151WRK5   A0A3L8D4Y7   A0A026VVA8   F4WWH8   A0A195FBR8   E2A7U7   V5GI73   A0A195CJV0   A0A1B6LR23   A0A1B6K3S3   D6WPZ7   A0A067RMB0   U4UET3   A0A2S2QIL3   A0A336MUE1   A0A2S2QM85   A0A1B6C087   X1WQ75   A0A2H8TIN6   A0A2S2PD03   B4N066   A0A1Y1MVA7   A0A0J9QXD3   E0VK48   N6UH02   A0A1D2NBX7   A0A1W4UNQ6   B3N5Y6   M9PEY6   Q9VM71   B4NZZ6   A0A182Y764   B3MKR2   Q29JY3   B0X5B1   A0A1J1ITU8   A0A3B0K960   A0A182FAU3   A0A2M4BBN1   U5ENK1   A0A2M4A8Y5   A0A2M4BBL7   B4LVQ4   B4KBG4   A0A2M3Z6L9   A0A182VNF3   A0A182XFI6   E9IBY6   A0A2M4CYG9   A0A182L7N1   A0A182TZ61   Q7QH49   A0A1I8N057   W5JFP1   T1PN42   A0A2I6QAZ6   A0A182JR13   A0A1B0CBG4   A0A1L8DX94   A0A182I810   B4JHR5   A0A084WNP7   A0A0L0C179   A0A1I8PEM7   A0A182N5J5   A0A182QMX3   A0A182LV51   A0A182W0F4   A0A1A9W436   A0A034WCA0   A0A0P6IB77   A0A0P6FY68   A0A0P5J3T7   A0A0P6CSI0   A0A1Q3G151   A0A1Q3G127   A0A0P6F9D9   A0A0P5HCT6   A0A182SV76   A0A0P6FQ08  

EC Number

3.1.13.-

Pubmed

22118469    26354079    20798317    28648823    21347285    30249741    + More
24508170    21719571    18362917    19820115    24845553    23537049    17994087    28004739    22936249    20566863    27289101    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17363252    18327897    17550304    25244985    15632085    21282665    20966253    12364791    14747013    17210077    25315136    20920257    23761445    29288727    24438588    26108605    25348373   

EMBL

GDQN01011633    JAT79421.1    ODYU01008185    SOQ51573.1    RSAL01000004    RVE54550.1    + More
AGBW02011505    OWR46548.1    KQ460205    KPJ17028.1    KQ459604    KPI92109.1    GBYB01007021    JAG76788.1    KQ434809    KZC06220.1    GL449036    EFN83355.1    KQ980886    KYN11858.1    NNAY01001415    OXU24047.1    KQ414667    KOC64743.1    KQ435863    KOX70353.1    ADTU01018937    ADTU01018938    ADTU01018939    ADTU01018940    ADTU01018941    ADTU01018942    KQ976439    KYM86732.1    JR049900    AEY61114.1    KZ288194    PBC33944.1    KQ982805    KYQ50539.1    QOIP01000013    RLU15562.1    KK107796    EZA47718.1    GL888406    EGI61520.1    KQ981693    KYN37853.1    GL437405    EFN70493.1    GALX01004712    JAB63754.1    KQ977649    KYN00722.1    GEBQ01013786    JAT26191.1    GECU01001595    JAT06112.1    KQ971354    EFA06899.2    KK852425    KDR24133.1    KB632149    ERL89121.1    GGMS01008386    MBY77589.1    UFQT01002127    SSX32719.1    GGMS01009673    MBY78876.1    GEDC01030619    JAS06679.1    ABLF02017552    GFXV01002179    MBW13984.1    GGMR01014653    MBY27272.1    CH963920    EDW78001.2    GEZM01021201    JAV89088.1    CM002910    KMY88643.1    AAZO01002977    DS235239    EEB13754.1    APGK01020735    APGK01020736    KB740234    ENN81000.1    LJIJ01000097    ODN02741.1    CH954177    EDV59145.1    AE014134    AGB92702.1    BT021334    BT056259    CM000157    EDW87823.1    CH902620    EDV31593.1    CH379062    EAL32828.2    DS232374    EDS40796.1    CVRI01000059    CRL03012.1    OUUW01000006    SPP81561.1    GGFJ01001296    MBW50437.1    GANO01000572    JAB59299.1    GGFK01003942    MBW37263.1    GGFJ01001295    MBW50436.1    CH940650    EDW66477.2    CH933806    EDW13631.2    GGFM01003400    MBW24151.1    GL762137    EFZ21920.1    GGFL01006204    MBW70382.1    AAAB01008817    EAA05380.5    ADMH02001283    ETN63192.1    KA650129    AFP64758.1    MG386507    AUM86165.1    AJWK01005130    AJWK01005131    GFDF01003038    JAV11046.1    APCN01002607    CH916369    EDV93904.1    ATLV01024644    KE525354    KFB51841.1    JRES01001042    KNC26021.1    AXCN02001165    AXCM01007326    GAKP01007524    JAC51428.1    GDIQ01023505    JAN71232.1    GDIQ01042598    JAN52139.1    GDIQ01205783    JAK45942.1    GDIQ01087882    JAN06855.1    GFDL01001535    JAV33510.1    GFDL01001534    JAV33511.1    GDIQ01052746    JAN41991.1    GDIQ01228727    JAK22998.1    GDIQ01044800    JAN49937.1   

Proteomes

UP000283053    UP000007151    UP000053240    UP000053268    UP000076502    UP000192223    + More
UP000008237    UP000078492    UP000215335    UP000053825    UP000053105    UP000005205    UP000005203    UP000078540    UP000242457    UP000075809    UP000279307    UP000053097    UP000007755    UP000078541    UP000000311    UP000078542    UP000007266    UP000027135    UP000030742    UP000007819    UP000007798    UP000009046    UP000019118    UP000094527    UP000192221    UP000008711    UP000000803    UP000002282    UP000076408    UP000007801    UP000001819    UP000002320    UP000183832    UP000268350    UP000069272    UP000008792    UP000009192    UP000075903    UP000076407    UP000075882    UP000075902    UP000007062    UP000095301    UP000000673    UP000075881    UP000092461    UP000075840    UP000001070    UP000030765    UP000037069    UP000095300    UP000075884    UP000075886    UP000075883    UP000075920    UP000091820    UP000075901   

PRIDE

M9PEY6    Q9VM71   

Pfam

PF17846   XRN_M        + More
PF03159   XRN_N

Interpro

IPR027073   5_3_exoribonuclease        + More
IPR004859   Put_53exo       
IPR041412   Xrn1_helical       
IPR017151   Xrn2/3/4       
IPR001878   Znf_CCHC       

ProteinModelPortal

A0A1E1VXM3   A0A2H1WES3   A0A3S2P1B9   A0A212EYH4   A0A194RGT2   A0A194PHC4   + More
A0A0C9RJG1   A0A154P516   A0A1W4WK74   A0A1W4WK62   E2BLM1   A0A195DG40   A0A232F0M1   A0A0L7R1M4   A0A0M8ZVB7   A0A158NKN8   A0A087ZZT3   A0A195BLW1   V9ILF4   A0A2A3ER15   A0A151WRK5   A0A3L8D4Y7   A0A026VVA8   F4WWH8   A0A195FBR8   E2A7U7   V5GI73   A0A195CJV0   A0A1B6LR23   A0A1B6K3S3   D6WPZ7   A0A067RMB0   U4UET3   A0A2S2QIL3   A0A336MUE1   A0A2S2QM85   A0A1B6C087   X1WQ75   A0A2H8TIN6   A0A2S2PD03   B4N066   A0A1Y1MVA7   A0A0J9QXD3   E0VK48   N6UH02   A0A1D2NBX7   A0A1W4UNQ6   B3N5Y6   M9PEY6   Q9VM71   B4NZZ6   A0A182Y764   B3MKR2   Q29JY3   B0X5B1   A0A1J1ITU8   A0A3B0K960   A0A182FAU3   A0A2M4BBN1   U5ENK1   A0A2M4A8Y5   A0A2M4BBL7   B4LVQ4   B4KBG4   A0A2M3Z6L9   A0A182VNF3   A0A182XFI6   E9IBY6   A0A2M4CYG9   A0A182L7N1   A0A182TZ61   Q7QH49   A0A1I8N057   W5JFP1   T1PN42   A0A2I6QAZ6   A0A182JR13   A0A1B0CBG4   A0A1L8DX94   A0A182I810   B4JHR5   A0A084WNP7   A0A0L0C179   A0A1I8PEM7   A0A182N5J5   A0A182QMX3   A0A182LV51   A0A182W0F4   A0A1A9W436   A0A034WCA0   A0A0P6IB77   A0A0P6FY68   A0A0P5J3T7   A0A0P6CSI0   A0A1Q3G151   A0A1Q3G127   A0A0P6F9D9   A0A0P5HCT6   A0A182SV76   A0A0P6FQ08  

PDB

5FIR     E-value=7.62865e-156,     Score=1412

KEGG

101746473    K12619 5'-3' exoribonuclease 2 [EC:3.1.13.-] | (RefSeq) 5'-3' exoribonuclease 2 homolog

GO

GO:0003676   GO:0004527   GO:0005634   GO:0004534   GO:0006397   GO:0008270   GO:0008409   GO:0006353   GO:0000738   GO:0046872   GO:0006886   GO:0016192   GO:0030117   GO:0007154   GO:0016020   GO:0005112   GO:0015930  

PANTHER

PTHR12341  

Subcellular location

Nucleus  

Length:

450

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00168

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00066

outside

1  -  450

 

 

Pi

292.573803

Theta

214.720987

Tajima's D

0.949872

CLR

0.081818

CSRT

0.644867756612169

Interpretation

Uncertain