Gene

KWMTBOMO14944

Pre Gene Modal

BGIBMGA000765

Annotation

PREDICTED:_ribosome-releasing_factor_2?_mitochondrial_[Amyelois_transitella]

Location

Bomo_Chr25(-):878094-889842      View in EpiBrowser

Full name

Ribosome-releasing factor 2, mitochondrial      

Alternative Name

Elongation factor G 2, mitochondrial
Elongation factor G2

Location in the cell

Cytoplasmic   Reliability : 2.211

CDS

ATGGAAAATATTCGTAATATTGGTATTTTAGCGCACATTGATGCAGGTAAAACAACGACAACAGAAAGAATGCTGTTTTACTCAGGCACCATCAGATCTATGGGAGAGGTGCATCATGGGAATACCGTCACAGATTACATGGAACAAGAGAGGCAAAGGGGAATCACAATCACTTCTGCAGCAGTAACAATCCCTTGGAGAGGAGGGCAGATCAATCTAATAGATACACCAGGACACATAGACTTCACAATGGAGGTCGAACAGAGTTTGGCTGTTCTCGATGGTGCAGTTATAGTCCTTGATGGATCTGCCGGTGTCGAAGCACAAACATTAACAGTGTGGAGACAGGCCATCGGGTACAGAGTACCTCGGATACTCTACTTAAACAAGATGGACAGGAATGACGCATTCGTGGAGGCTTGCGTGAACTCGGTCACAGAGAAGCTGCAAGCCACGCCTTTGCTACTCCACCACACCGTTAGGCACGAAGGACGACTCATTGGACTAATAGATTTAATTAACCTAGAAGAGATAATATGGACTCAAGGACGAGGACAGAAGTTCACTCGAAGAAAACTGACGGAGAAAGACGACGGTCACAAATGGGAGGCGGCCGTTACTGACCATAGACAACTCGTGGACACTCTCTCTTCTATAGACGATGAGATAGCAGAGACAATCATAAACAACGAGTCTTTGGAGTTGAGCGCACGCGACATAGACAATGCGGTCAGAAGATCTACTATTAAAATGAAAGCTTTTCCCATTTTGTGTGGAAGTTCTTATAAAAATATAGGGGTTCAAACCTTGATGGACGGTGTCATGTCATATCTTCCAAGTCCCCTGGAAGGACACGAGCTGTATAAATGTTTCGGTGAGGAGCTAGCGGGCAGGGCTTTCAAAGTGATCCACGACGACCAGAGGGGAGTGCTGACCTTCGTGAGGCTGTACAGCGGCGAGATGAAGAAGGCCCAGAAGATCTACAACCTTGGACAGGACAGAAGCGAGCAGACGGGCGCGCTGTACGTGGCGTTGGCTGACGAGTATCGTCCAGTGGAGTCAGTGGCCGCGGGCAACATCGCCGTCGTGGGGTCACTCAAGGCGACCATGACGGGGGACCTGGTCACGTCCACACAAGCGGCGGCCAACAGGGCCCGGGGTCGGCTGGCGACGCTGCTCCGCCTCCCCGGGCGGGCGGAGGAGCTGATGCTGCCCAGCGCCAGGCAGAGGCTGCAGGCTCTCGACTCTGAACCAGAGCCTGAGGAACTTGCAGAAATTCTGCTCGGCATCGGCACCACCGTGCCCGAGCCCGTGTTCCTGTGCTCCATCGAGCCCCCCAGCGCCATGCACCAGGCGGCGCTGGAGACGGCGCTGGAGCAGCTGCAGCGGGAGGACCCGAGCCTCAGGGTCAACGCGGATGACGAAAGCGGACAGATCGTATTGGCCGGTATGGGCGAGCTCCACCTGGAAATCATAAAGGAGCGCATCATCAGAGAGTACAAGATAGACGTGGAGCTGGGCCCGCTGCAGATAGCGTACCGGGAGGCGCTGGTCTCTTCCGGCAAGAACACGCTCACTGTGGACAGGAAGATCGGCGGCGCCAGGCAGCAGCTGAAGGTCACCATGTCCGCCAGGACCGTCAAGGGAGTCGCTCAGGATAAGATCCTCAGGTTAGATAAGACGGTCGAGAGCGCGTCGAACCTCGCGCATCTGCACCCGCGGCAGCTGCAGGCCGTGCGGCAGGGGGTCGCCGCCGCGCTGCTGCACGGGCCCAAGCTCGGCTGTCCGGTGGTGGACGTGCAGGTGACGCTGCACTGGTTCGAGTCCGGGCGCGGCACCTCCGACTCCGTAGTGACGGCGTCCGTCGCCCAGTGCTTGAGGAAGGTGTTCGAAGAGGCGGACTCGATCCTCCTGGAGCCGGTGATGTCGCTGGAGGTGGTGTGTCCCGAGACGCACTCTCAGAGGGTGCTGGCCGACCTCTCGCGGCGGAGGGTCGAGGTGCAGCACATCCAGCTGCGACAACACAACAAGGTGATAGAGTGCATAGCTCCGCTGTCGGAGGTGGTGGGCTACTCGTCGACGCTGCGCTCGCTGAGCTCGGGGCTGGCCACCTTCTCCATGCAGTTCCACTCGCACCGCCAGATGGCGCCGCAACACGAGCAGCTCGCCGTCAAGAATGTCACCGGGTTCTAG

Protein

MENIRNIGILAHIDAGKTTTTERMLFYSGTIRSMGEVHHGNTVTDYMEQERQRGITITSAAVTIPWRGGQINLIDTPGHIDFTMEVEQSLAVLDGAVIVLDGSAGVEAQTLTVWRQAIGYRVPRILYLNKMDRNDAFVEACVNSVTEKLQATPLLLHHTVRHEGRLIGLIDLINLEEIIWTQGRGQKFTRRKLTEKDDGHKWEAAVTDHRQLVDTLSSIDDEIAETIINNESLELSARDIDNAVRRSTIKMKAFPILCGSSYKNIGVQTLMDGVMSYLPSPLEGHELYKCFGEELAGRAFKVIHDDQRGVLTFVRLYSGEMKKAQKIYNLGQDRSEQTGALYVALADEYRPVESVAAGNIAVVGSLKATMTGDLVTSTQAAANRARGRLATLLRLPGRAEELMLPSARQRLQALDSEPEPEELAEILLGIGTTVPEPVFLCSIEPPSAMHQAALETALEQLQREDPSLRVNADDESGQIVLAGMGELHLEIIKERIIREYKIDVELGPLQIAYREALVSSGKNTLTVDRKIGGARQQLKVTMSARTVKGVAQDKILRLDKTVESASNLAHLHPRQLQAVRQGVAAALLHGPKLGCPVVDVQVTLHWFESGRGTSDSVVTASVAQCLRKVFEEADSILLEPVMSLEVVCPETHSQRVLADLSRRRVEVQHIQLRQHNKVIECIAPLSEVVGYSSTLRSLSSGLATFSMQFHSHRQMAPQHEQLAVKNVTGF

Description

Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.

Similarity

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

Keywords

Complete proteome   GTP-binding   Mitochondrion   Nucleotide-binding   Protein biosynthesis   Reference proteome   Transit peptide  

Feature

chain  Ribosome-releasing factor 2, mitochondrial

Uniprot

H9IU35   A0A2W1BYG6   A0A2A4J5K6   A0A194PFP7   A0A2H1WFC6   A0A3S2M9K1   + More
A0A212EYL2   A0A194RGT7   A0A1B6CPE1   A0A2P8Y271   A0A151WQ12   A0A195C310   A0A158NJ41   A0A195DJU9   F4W794   A0A195BL22   A0A0C9REE6   E1ZVL4   D6WPX8   A0A1B6J8A0   E2BK05   A0A0L7KHK7   A0A1B6GLX8   A0A026VVW9   A0A1Y1N3N6   A0A3L8DDX8   E9IT92   A0A1B6KGD5   J9JKG8   A0A232FGQ4   A0A087ZT96   A0A067REY6   A0A195EYS5   K7J309   A0A3R7QK99   A0A1B6EU19   A0A0M9A4I1   N6UEF1   A0A0Q9XCL1   A0A0J7L6I1   B4JSI3   B4NAU8   A0A0P4W9E1   Q29BD5   B4GNT0   B3M011   A0A0M3QXL7   A0A1A9VVW3   A0A3B0JJ22   A0A1A9Z3R1   A0A1A9XFK6   A0A1J1J0F0   A0A0L7QMD6   A0A1Y1MZ82   A0A1W4W1J0   A0A1A9WRW7   A0A0K8UAG6   B3P8M3   A0A0A1X4W8   Q9VCX4   A0A0L0BS17   A0A1I8MHD4   B0W010   B4M416   I1WYH6   A0A226F0P9   A0A0P6IYK0   A0A1S4FZT8   A0A1Q3F921   A0A1I8PK89   A0A182TL00   A0A182WTC1   A0A182HVB4   A0A182M335   A0A182L264   A0A182VKM0   A0A1S4GWL9   A0A293LH03   A0A182GKZ0   A0A182GL48   A0A0P5HXK6   A0A0P6BC28   A0A182W9S8   A0A0P6IQC6   A0A182ST14   A0A182NE67   A0A1D2MVA9   A0A3S1BRK1   A0A182QEH8   A0A164LWQ0   A0A182RBQ2   E9FU13   A0A182YGX6   A0A2A3EC44   F7G7T5   T1HV44   A0A0K8UG02   A0A0N8CEK7   A0A154P443   C3YQ46  

Pubmed

19121390    28756777    26354079    22118469    29403074    21347285    + More
21719571    20798317    18362917    19820115    26227816    24508170    28004739    30249741    21282665    28648823    24845553    20075255    23537049    17994087    15632085    25830018    20132446    21364917    10731132    12537572    26108605    25315136    26999592    17510324    20966253    12364791    26483478    27289101    21292972    25244985    18464734    18563158   

EMBL

BABH01034221    KZ149945    PZC76813.1    NWSH01002867    PCG67417.1    KQ459604    + More
KPI92112.1    ODYU01008185    SOQ51572.1    RSAL01000004    RVE54549.1    AGBW02011505    OWR46547.1    KQ460205    KPJ17033.1    GEDC01021951    JAS15347.1    PYGN01001024    PSN38358.1    KQ982845    KYQ49989.1    KQ978317    KYM95249.1    ADTU01017434    KQ980804    KYN12769.1    GL887813    EGI69978.1    KQ976453    KYM85469.1    GBYB01006715    JAG76482.1    GL434548    EFN74783.1    KQ971354    EFA06892.2    GECU01012316    JAS95390.1    GL448708    EFN84014.1    JTDY01009882    KOB62369.1    GECZ01006323    JAS63446.1    KK107746    EZA47943.1    GEZM01017039    JAV90946.1    QOIP01000010    RLU18099.1    GL765502    EFZ16193.1    GEBQ01029457    JAT10520.1    ABLF02029984    NNAY01000228    OXU29872.1    KK852510    KDR22332.1    KQ981920    KYN33034.1    QCYY01000951    ROT81595.1    GECZ01028401    JAS41368.1    KQ435736    KOX77080.1    APGK01025659    APGK01025660    KB740600    ENN80090.1    CH933806    KRG02113.1    LBMM01000467    KMQ98266.1    CH916373    CH964232    GDRN01107375    JAI57421.1    CM000070    CH479186    CH902617    CP012526    ALC46089.1    OUUW01000005    SPP80753.1    CVRI01000066    CRL06003.1    KQ414894    KOC59750.1    GEZM01017040    JAV90944.1    GDHF01028685    JAI23629.1    CH954182    GBXI01012635    GBXI01008381    JAD01657.1    JAD05911.1    AB514521    JF309280    AE014297    JRES01001565    KNC22009.1    DS231816    CH940652    BT133496    AFI71926.1    LNIX01000001    OXA62994.1    GDUN01000985    JAN94934.1    GFDL01010985    JAV24060.1    APCN01002504    AXCM01000141    AAAB01008964    GFWV01003064    MAA27794.1    JXUM01070964    KQ562637    KXJ75439.1    JXUM01071241    KQ562651    KXJ75401.1    GDIQ01220837    JAK30888.1    GDIP01017217    JAM86498.1    GDIQ01018632    JAN76105.1    LJIJ01000486    ODM96936.1    RQTK01000965    RUS73209.1    AXCN02000870    LRGB01003123    KZS04507.1    GL732524    EFX89545.1    KZ288305    PBC28769.1    AAPN01106516    AAPN01106517    AAPN01106518    ACPB03009292    GDHF01026821    JAI25493.1    GDIP01139391    JAL64323.1    KQ434809    KZC06617.1    GG666540    EEN57550.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000283053    UP000007151    UP000053240    + More
UP000245037    UP000075809    UP000078542    UP000005205    UP000078492    UP000007755    UP000078540    UP000000311    UP000007266    UP000008237    UP000037510    UP000053097    UP000279307    UP000007819    UP000215335    UP000005203    UP000027135    UP000078541    UP000002358    UP000283509    UP000053105    UP000019118    UP000009192    UP000036403    UP000001070    UP000007798    UP000001819    UP000008744    UP000007801    UP000092553    UP000078200    UP000268350    UP000092445    UP000092443    UP000183832    UP000053825    UP000192221    UP000091820    UP000008711    UP000000803    UP000037069    UP000095301    UP000002320    UP000008792    UP000198287    UP000095300    UP000075902    UP000076407    UP000075840    UP000075883    UP000075882    UP000075903    UP000069940    UP000249989    UP000075920    UP000075901    UP000075884    UP000094527    UP000271974    UP000075886    UP000076858    UP000075900    UP000000305    UP000076408    UP000242457    UP000002279    UP000015103    UP000076502    UP000001554   

PRIDE

H9IU35    B4JSI3    B3P8M3    Q9VCX4    B4M416    I1WYH6    + More

Pfam

PF00009   GTP_EFTU        + More
PF00679   EFG_C
PF14492   EFG_II
PF03144   GTP_EFTU_D2
PF03764   EFG_IV
PF01084   Ribosomal_S18
PF01991   vATP-synt_E

Interpro

IPR041095   EFG_II        + More
IPR009000   Transl_B-barrel_sf       
IPR035649   EFG_V       
IPR027417   P-loop_NTPase       
IPR035647   EFG_III/V       
IPR020568   Ribosomal_S5_D2-typ_fold       
IPR031157   G_TR_CS       
IPR000795   TF_GTP-bd_dom       
IPR009022   EFG_III       
IPR005225   Small_GTP-bd_dom       
IPR000640   EFG_V-like       
IPR014721   Ribosomal_S5_D2-typ_fold_subgr       
IPR004161   EFTu-like_2       
IPR005517   Transl_elong_EFG/EF2_IV       
IPR001648   Ribosomal_S18       
IPR036870   Ribosomal_S18_sf       
IPR030851   EFG2       
IPR038495   ATPase_E_C       
IPR002842   ATPase_V1_Esu       

SUPFAM

SSF50447   SSF50447        + More
SSF54980   SSF54980       
SSF52540   SSF52540       
SSF54211   SSF54211       
SSF46911   SSF46911       

Gene 3D

3.30.230.10     4.10.640.10     3.30.2320.30    

CDD

cd03713  EFG_mtEFG_C
cd16262  EFG_III

ProteinModelPortal

H9IU35   A0A2W1BYG6   A0A2A4J5K6   A0A194PFP7   A0A2H1WFC6   A0A3S2M9K1   + More
A0A212EYL2   A0A194RGT7   A0A1B6CPE1   A0A2P8Y271   A0A151WQ12   A0A195C310   A0A158NJ41   A0A195DJU9   F4W794   A0A195BL22   A0A0C9REE6   E1ZVL4   D6WPX8   A0A1B6J8A0   E2BK05   A0A0L7KHK7   A0A1B6GLX8   A0A026VVW9   A0A1Y1N3N6   A0A3L8DDX8   E9IT92   A0A1B6KGD5   J9JKG8   A0A232FGQ4   A0A087ZT96   A0A067REY6   A0A195EYS5   K7J309   A0A3R7QK99   A0A1B6EU19   A0A0M9A4I1   N6UEF1   A0A0Q9XCL1   A0A0J7L6I1   B4JSI3   B4NAU8   A0A0P4W9E1   Q29BD5   B4GNT0   B3M011   A0A0M3QXL7   A0A1A9VVW3   A0A3B0JJ22   A0A1A9Z3R1   A0A1A9XFK6   A0A1J1J0F0   A0A0L7QMD6   A0A1Y1MZ82   A0A1W4W1J0   A0A1A9WRW7   A0A0K8UAG6   B3P8M3   A0A0A1X4W8   Q9VCX4   A0A0L0BS17   A0A1I8MHD4   B0W010   B4M416   I1WYH6   A0A226F0P9   A0A0P6IYK0   A0A1S4FZT8   A0A1Q3F921   A0A1I8PK89   A0A182TL00   A0A182WTC1   A0A182HVB4   A0A182M335   A0A182L264   A0A182VKM0   A0A1S4GWL9   A0A293LH03   A0A182GKZ0   A0A182GL48   A0A0P5HXK6   A0A0P6BC28   A0A182W9S8   A0A0P6IQC6   A0A182ST14   A0A182NE67   A0A1D2MVA9   A0A3S1BRK1   A0A182QEH8   A0A164LWQ0   A0A182RBQ2   E9FU13   A0A182YGX6   A0A2A3EC44   F7G7T5   T1HV44   A0A0K8UG02   A0A0N8CEK7   A0A154P443   C3YQ46  

PDB

6NOT     E-value=1.58234e-115,     Score=1067

KEGG

101746335    K02355 elongation factor G | (RefSeq) ribosome-releasing factor 2, mitochondrial

GO

GO:0005525   GO:0003924   GO:0003746   GO:0032790   GO:0006412   GO:0003735   GO:0005840   GO:0032543   GO:0005739   GO:0033178   GO:0046961   GO:0015991   GO:0016021   GO:0032264   GO:0006886   GO:0016192   GO:0030117   GO:0007154   GO:0016020   GO:0005112   GO:0015930  

Subcellular location

Mitochondrion  

Length:

730

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01229

Exp number, first 60 AAs:

0.00282

Total prob of N-in:

0.00066

outside

1  -  730

 

 

Pi

267.401805

Theta

178.897439

Tajima's D

1.684151

CLR

0.324704

CSRT

0.822558872056397

Interpretation

Uncertain