Gene

KWMTBOMO14943  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000807

Annotation

PREDICTED:_AMP_deaminase_2-like_[Amyelois_transitella]

Location

Bomo_Chr25(+):861153-877184      View in EpiBrowser

Full name

AMP deaminase      

Location in the cell

Mitochondrial   Reliability : 2.027

CDS

ATGATGAAAGATGTCAAAAAATGCGAAGCGAACGATAATGCGGTCGCAGCGACGCGCACACATGTTCGAGGTCCCGGCGACAGCACGCGGCGCCGTGCCGACAACCAGGTCCCGTTCCAGAGAGTCTCCGTCGCCGGTATACATATCACTGGGGTGCCCATAGAGGAGTTGATACGTTCAGCCACTCTGCTGGTCGAAGCGTTGGGCTTGCGTCGCTACTACATGGAGGCCGCCCAGCAGTCCTTCCCGGAGACGCTGGTGGAGTTCTTCTCCGGGCACGGCTCCCCGCGGCGAATGCTCGACAAGCACAAGGAATCTATGGACTTTACTCGCGCTTTACTTAATTTGGACAGACTCGTGGACCCGTGGGCTTGTCCAAGCCCCCCAGATCGGCGGTACTCGTTCCGATGGGTGGACGGTGTGGTCGCGGTCTACCGCAGCGAGGGTGATGCGGCTTCGGGCAGGCCCTTACCTTACCGCACCGTCAAATTCAAGCAGTACGTCGACGATATGGGGAAGCTGAGTGACATGGTCGCTGATGGACCGCTGAAATCGTTTTGTTTTCGTCGTCTGAGCTACCTGAAGTCTAAGTTCAAGATGCACGTACTGCTGAATGAGCTTCACGAGCTGGCTTTACAGAAAGCTGTTCCGCATCGAGACTTCTACAACATCAGAAAAGTGGATACTCACATTCACGCTGCGTCGTGCATGAACCAGAAACATTTGTTGCGGTTCATCAAGCGTACCCTGCGGCAGAACGCCCACGAGGTGGTGGCCTTGCAACGCGGGGTCCCGATGACCCTCAAATCTGTGTTTGAGGAGATGCAGCTCGACGCCTACGACCTCAACGTTGACATACTGGACGTTCACGCGGACCGCAACACTTTCCATCGTTTTGATAAGTTCAATGCCAAATACAATCCGGTCGGAGAGAGCCGACTGAGGGAAGTGTTCTTGAAGACCGACAACTACATGAACGGAACGTATTTCGCCAACATCATTAAGGAAGTGATGTCGGATTTCGCAGAGAATAAGTACACGTACTCCGAGCCCCGCATCTCGGTGTACTGCAAGAGCAGCAGCGAGTGGAGTCGGCTGGCGTCGTGGGCGGTCCGGAACGACGTGCACTCGCCCCACGTGAGGTGGCTCGTGCAGGTCCCCAGGCTCTATGATATCTACCGCATCAACAAGTTGCTGAAGAATTTCCAGCAGTTTCTGAGCAACCTTTTTGATCCGTTGTTTGAAGTTTCCATCGACCCCAGTTCCAATCCGGAGCTGCACAAATTCTTGGCGCACGTGATCGGGTTCGATAGCGTGGACGATGAGTCCAAGCCGGAGATCCCGAACCTCAGCGAACATATGAGAACTCCCGAGGAATGGAACGACGAGGAGAACCCTCCGTACGCGTACTACCTGTACTACATGTACGCTAACATGGTCACCCTCAATGAGTTGCGCAAGGAGCAGGGGCTGAACACATTCGTGCTGCGCCCCCACTGCGGGGAGGCCGGGCCCGCCGCGCACCTGAGCGCCGGATTCCTCCTCGCCGAGAACATATCTCACGGACTCATCCTGAGAAAGGTGCCCGTGCTCCAGTACGCGTACTACTTGGCCCAGATCTACATCGCGATGTCTCCGCTCAGCAACAACTCGCTGTTCCTCAACTACCATAGGAACCCGCTGCCAGAGTACTTCGCGAGAGGACTCCGGGTCACTCTGAGCACTGATGATCCTCTGCAGTTCCATTTTACTAGGGAGCCGCTGATGGAGGAGTACAGTATAGCCGCGCAGGCGTGGAAGCTCAGCTCGTGCGACATGTGCGAGCTGGCCAGAAACTCTGTGCTCATGTCCGGGTTCCCGCACGAGATGAAGCAGTACTGGCTGGGCGCGCAGTACGTGCACGAGGGTCCGGCCGGGAACGACATCACCAAGACCAACGTCCCCGACGTCAGGATCTCGTTCCGCCACGAGACCTTACTCGACGAGCTGGACAACTTGTTTAGCGCAGCCGAAAAATAA

Protein

MMKDVKKCEANDNAVAATRTHVRGPGDSTRRRADNQVPFQRVSVAGIHITGVPIEELIRSATLLVEALGLRRYYMEAAQQSFPETLVEFFSGHGSPRRMLDKHKESMDFTRALLNLDRLVDPWACPSPPDRRYSFRWVDGVVAVYRSEGDAASGRPLPYRTVKFKQYVDDMGKLSDMVADGPLKSFCFRRLSYLKSKFKMHVLLNELHELALQKAVPHRDFYNIRKVDTHIHAASCMNQKHLLRFIKRTLRQNAHEVVALQRGVPMTLKSVFEEMQLDAYDLNVDILDVHADRNTFHRFDKFNAKYNPVGESRLREVFLKTDNYMNGTYFANIIKEVMSDFAENKYTYSEPRISVYCKSSSEWSRLASWAVRNDVHSPHVRWLVQVPRLYDIYRINKLLKNFQQFLSNLFDPLFEVSIDPSSNPELHKFLAHVIGFDSVDDESKPEIPNLSEHMRTPEEWNDEENPPYAYYLYYMYANMVTLNELRKEQGLNTFVLRPHCGEAGPAAHLSAGFLLAENISHGLILRKVPVLQYAYYLAQIYIAMSPLSNNSLFLNYHRNPLPEYFARGLRVTLSTDDPLQFHFTREPLMEEYSIAAQAWKLSSCDMCELARNSVLMSGFPHEMKQYWLGAQYVHEGPAGNDITKTNVPDVRISFRHETLLDELDNLFSAAEK

Catalytic Activity

AMP + H(+) + H2O = IMP + NH4(+)

Cofactor

Zn(2+)

Similarity

Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

Uniprot

H9IU77   A0A212EYH5   A0A2W1BP30   A0A2A4J6Q5   A0A2H1WEU0   A0A194RI81   + More
A0A194PGF8   A0A194PHC8   A0A2H1WEQ9   H9IU76   A0A212EYI0   A0A2W1BR58   A0A2A4J7M0   A0A2A4J5Q4   A0A2A4J7N2   E2B347   A0A026WZW8   A0A3S2NM78   E1ZV26   A0A151WZZ4   A0A195AW79   A0A195FJD1   A0A1Y1KCB1   A0A182N109   A0A1Y1KFC9   F4W6E6   A0A1Y1KES6   A0A1Y1KH92   A0A1Y1K9T8   A0A195DMH5   A0A0L7QTV6   A0A1L8DY01   R4WJZ6   A0A2A3E3T1   A0A1B6LF21   A0A1B6LWC6   K7IR89   A0A1B6LRF2   A0A182QHY2   A0A182V244   A0A182IA57   A0A182XLP6   A0A1W4XN33   A0A182PQ60   A0A0A9W2W7   A0A1L8DXX6   A0A1L8DXU6   A0A0K8TDN6   A0A2J7QUJ3   A0A088A084   A0A0A9WA91   A0A0A9W5I4   H2KMF2   A0A182RV49   A0A2M4CW16   S4PD75   A0A0P6IYH3   A0A1I8M5T7   A0A2J7QUI7   A0A158P2M1   A0A1Q3G438   A0A084VAB0   A0A182JES1   F5HJE6   A0A2M4CXG1   A0A0P8ZJ64   A0A2M3ZYQ5   A0A182MF03   A0A1Q3G448   A0A182W4Q8   A0A2M3ZYP0   F5HJE7   F5HJE8   A0A182H3L0   A0A154PRN9   T1DJB0   A0A0P9A912   A0A2M4BE94   A0A2M4BEH8   A0A2M4BEB1   W5JP02   A0A0P8XIU9   A0A2M3ZFZ9   A0A2M4BEW8   B3MZS4   T1PNB5   T1PCR1   A0A1I8M5T5   A0A1I8PX41   A0A0K8TSL1   A0A1I8PX13   A0A182Y7H3   A0A1I8M5T6   A0A1I8M5T9   A0A1I8M5T4   A0A1W4XM87   A0A1W4XCP1   A0A067RGI2   A0A0P8XJ75   A0A1W4XD08  

EC Number

3.5.4.6

Pubmed

19121390    22118469    28756777    26354079    20798317    24508170    + More
28004739    21719571    23691247    20075255    25401762    26823975    12364791    14747013    17210077    23622113    26999592    25315136    21347285    24438588    17994087    26483478    20920257    23761445    26369729    25244985    24845553   

EMBL

BABH01034221    AGBW02011505    OWR46546.1    KZ149945    PZC76812.1    NWSH01002867    + More
PCG67416.1    ODYU01008185    SOQ51571.1    KQ460205    KPJ17035.1    KQ459604    KPI92113.1    KPI92114.1    SOQ51570.1    BABH01034219    BABH01034220    OWR46545.1    PZC76811.1    PCG67412.1    PCG67415.1    PCG67413.1    GL445285    EFN89896.1    KK107054    EZA61572.1    RSAL01000004    RVE54548.1    GL434395    EFN74955.1    KQ982625    KYQ53483.1    KQ976731    KYM76219.1    KQ981523    KYN40367.1    GEZM01088534    JAV58128.1    GEZM01088536    JAV58126.1    GL887707    EGI70281.1    GEZM01088537    JAV58125.1    GEZM01088535    JAV58127.1    GEZM01088538    JAV58124.1    KQ980724    KYN14036.1    KQ414740    KOC62055.1    GFDF01002812    JAV11272.1    AK417940    BAN21155.1    KZ288387    PBC26413.1    GEBQ01017682    JAT22295.1    GEBQ01011984    JAT27993.1    GEBQ01013760    JAT26217.1    AXCN02001394    APCN01001124    GBHO01041840    GBHO01041838    GBRD01002547    GDHC01012526    JAG01764.1    JAG01766.1    JAG63274.1    JAQ06103.1    GFDF01002825    JAV11259.1    GFDF01002813    JAV11271.1    GBRD01002546    JAG63275.1    NEVH01010578    PNF32244.1    GBHO01041839    GBHO01041837    JAG01765.1    JAG01767.1    GBHO01041842    GBHO01041841    GBRD01002545    JAG01762.1    JAG01763.1    JAG63276.1    AAAB01008846    EAA45063.5    GGFL01005355    MBW69533.1    GAIX01005062    JAA87498.1    GDUN01000039    JAN95880.1    PNF32246.1    ADTU01006991    ADTU01006992    GFDL01000477    JAV34568.1    ATLV01003052    KE524109    KFB34904.1    AXCP01007583    EGK96409.1    GGFL01005380    MBW69558.1    CH902635    KPU74815.1    GGFK01000352    MBW33673.1    AXCM01001247    GFDL01000460    JAV34585.1    GGFK01000353    MBW33674.1    EGK96407.1    EGK96408.1    JXUM01107648    KQ565160    KXJ71273.1    KQ435031    KZC14014.1    GAMD01001576    JAB00015.1    KPU74818.1    GGFJ01002235    MBW51376.1    GGFJ01002303    MBW51444.1    GGFJ01002244    MBW51385.1    ADMH02000938    ETN64625.1    KPU74817.1    GGFM01006672    MBW27423.1    GGFJ01002458    MBW51599.1    EDV33875.1    KA649555    AFP64184.1    KA646562    AFP61191.1    GDAI01000239    JAI17364.1    KK852478    KDR22976.1    KPU74819.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000053240    UP000053268    UP000008237    + More
UP000053097    UP000283053    UP000000311    UP000075809    UP000078540    UP000078541    UP000075884    UP000007755    UP000078492    UP000053825    UP000242457    UP000002358    UP000075886    UP000075903    UP000075840    UP000076407    UP000192223    UP000075885    UP000235965    UP000005203    UP000007062    UP000075900    UP000095301    UP000005205    UP000030765    UP000075880    UP000007801    UP000075883    UP000075920    UP000069940    UP000249989    UP000076502    UP000000673    UP000095300    UP000076408    UP000027135   

PRIDE

H9IU77    H9IU76   

Pfam

PF00962   A_deaminase

Interpro

IPR032466   Metal_Hydrolase        + More
IPR006329   AMPD       
IPR001365   A/AMP_deaminase_dom       
IPR006650   A/AMP_deam_AS       
IPR029749   AMPD2       

SUPFAM

SSF51556   SSF51556       

CDD

cd01319  AMPD

ProteinModelPortal

H9IU77   A0A212EYH5   A0A2W1BP30   A0A2A4J6Q5   A0A2H1WEU0   A0A194RI81   + More
A0A194PGF8   A0A194PHC8   A0A2H1WEQ9   H9IU76   A0A212EYI0   A0A2W1BR58   A0A2A4J7M0   A0A2A4J5Q4   A0A2A4J7N2   E2B347   A0A026WZW8   A0A3S2NM78   E1ZV26   A0A151WZZ4   A0A195AW79   A0A195FJD1   A0A1Y1KCB1   A0A182N109   A0A1Y1KFC9   F4W6E6   A0A1Y1KES6   A0A1Y1KH92   A0A1Y1K9T8   A0A195DMH5   A0A0L7QTV6   A0A1L8DY01   R4WJZ6   A0A2A3E3T1   A0A1B6LF21   A0A1B6LWC6   K7IR89   A0A1B6LRF2   A0A182QHY2   A0A182V244   A0A182IA57   A0A182XLP6   A0A1W4XN33   A0A182PQ60   A0A0A9W2W7   A0A1L8DXX6   A0A1L8DXU6   A0A0K8TDN6   A0A2J7QUJ3   A0A088A084   A0A0A9WA91   A0A0A9W5I4   H2KMF2   A0A182RV49   A0A2M4CW16   S4PD75   A0A0P6IYH3   A0A1I8M5T7   A0A2J7QUI7   A0A158P2M1   A0A1Q3G438   A0A084VAB0   A0A182JES1   F5HJE6   A0A2M4CXG1   A0A0P8ZJ64   A0A2M3ZYQ5   A0A182MF03   A0A1Q3G448   A0A182W4Q8   A0A2M3ZYP0   F5HJE7   F5HJE8   A0A182H3L0   A0A154PRN9   T1DJB0   A0A0P9A912   A0A2M4BE94   A0A2M4BEH8   A0A2M4BEB1   W5JP02   A0A0P8XIU9   A0A2M3ZFZ9   A0A2M4BEW8   B3MZS4   T1PNB5   T1PCR1   A0A1I8M5T5   A0A1I8PX41   A0A0K8TSL1   A0A1I8PX13   A0A182Y7H3   A0A1I8M5T6   A0A1I8M5T9   A0A1I8M5T4   A0A1W4XM87   A0A1W4XCP1   A0A067RGI2   A0A0P8XJ75   A0A1W4XD08  

PDB

2A3L     E-value=3.45642e-160,     Score=1452

KEGG

101746189    K01490 AMP deaminase [EC:3.5.4.6] | (RefSeq) AMP deaminase 2-like

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0046872   GO:0003876   GO:0032264   GO:0046033   GO:0005829   GO:0006188   GO:0019239   GO:0006886   GO:0016192   GO:0030117   GO:0007154   GO:0016020   GO:0005112   GO:0015930  

PANTHER

PTHR11359   PTHR11359:SF3  

Length:

672

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.51332

Exp number, first 60 AAs:

0.09296

Total prob of N-in:

0.00686

outside

1  -  672

 

 

Pi

252.817454

Theta

177.590628

Tajima's D

1.468938

CLR

0.340494

CSRT

0.777111144442778

Interpretation

Uncertain