Gene

KWMTBOMO14942  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000806

Annotation

PREDICTED:_AMP_deaminase_2_isoform_X3_[Bombyx_mori]

Location

Bomo_Chr25(+):820333-853521      View in EpiBrowser

Full name

AMP deaminase      

Location in the cell

Cytoplasmic   Reliability : 1.496 Nuclear   Reliability : 2.109

CDS

ATGTCCATCAGGGGTGTCCAGGACGGCTCCAGATCACCGTTGATCATCACCGATTCGTTCTTCGATGATGGCGGCAGTGAAAGTCCGACGAGCGCCGTGGGGGCGGAGGCGCCGCGGGAGCTCCCTAATGAACTCTCCGCGCCTTATGAAGTCCCGCAGTTTCCAATCGAACAAATCGAGAAGAAACTACTCATACAGAGGCAGCTGAATGTTAAGGCGGCGGAATGCGCTCAGTCTGTGCGTTCATTCGCGGGCAGCGAAGCAGGCGCGGCAGCCGTGTTTGAAGAGGCGGCTCGGCTCAGGGTCCCCGATGATGACGATGACGAGATCATCTTGCCGCACTTCCAGCGTGTCGCTATCAGCGGCGAGGATACTTCCGGGGTACCACTGGAAGATCTTCAACAAGCGTCCTCGTACCTGGTGCAGGCTCTGGAAATGCGCAAGCGTTACATGGAGATGTCCCAGCAGAGCTTCTCGCCCATTACGGCGCGCTTCATCAGGAGCATGGACGCGGATGCCGTAGCCAACCACGTACCCGTTAAAGTACCCAACAAACATATTGCGGACCATATAGTCCACCCTCCATTCAGAGACAAGGATCCGTGGGAATGTCCTATGCCGGAGCCCAAGGGCTACAGCATACGACTAAACAGGGGCGTGTTCAACATGTACCGCCAAGGACCGAACGGAGAGGAGCGACTGCCCTACGAATACATCACACTGGCGCAATACATCCAGGACATGAATACAATGTGCAACATGATCGCCGATGGTCCTCTAAAGTCCTTTTGCTACCGTCGCCTCAGCTACCTATCGTCCAAGTTCCAGCTCCACGTTCTGCTGAACGAGCTCAGGGAACTAGCTTCCCAGAAGGCAGTTCCTCATAGAGACTTCTACAATATCAGGAAGGTGGATACGCACATCCACGCGGCGTCTTGCATGAACCAGAAACACTTACTGCGGTTCATTAAGAAGACATTGAAGACGCATGCGGACGAGGTGGTGACCCTCCACAAAGGCACACCTATGACCCTGAGGTCTGTGTTCCAATCCATGAACCTGAGCACCTACGACCTCACCGTGGATATGCTGGACGTGCACGCGGACCGGAACACGTTCCATCGCTTCGACAAGTTCAACGCGAAGTACAACCCAATCGGGGAGAGCAGACTCCGCGAGGTGTTCCTCAAGACCGACAACTACATGAACGGAAAGTACTTCGCCAGGATCATTAAGGAGGTGGCGTCGGACCTGGAGGAGAGCAAGTACCAGAACGCGGAGCTGCGGCTGTCGGTGTACGGCAAGAGTCCCGGCGAGTGGGCCAAGCTCGCCAAGTGGGCCATCCAGTACGACGTGCACTCCAACAACGTGCGCTGGCTCATACAGATACCCCGCCTCTACGACATCTTCAAATCCAACAAAATAATGAACGACTTCCACGAGTTCTTGAACAACATCTTCCAGCCTCTCTTCGAAGTCACAAACGATCCTAACAGCAACATCGAGCTGCACAAGTTCCTCACACACGTGATCGGGTTCGACAGCGTGGACGACGAGTCCAAGCCCGAGAACCCGATGCTGGACACCGAAGTCAAAAGCCCCGAAGAGTGGGACGACGAGGAGAACCCTCCGTACGCGTACTACCTCTACTACATGTACGCCAACATGACTGTACTGAACCATTTCCGCAAGGAGCAAGGTCTGAACACGTTCGTCCTGCGTCCTCACTGCGGAGAGGCGGGTCCTGTACAGCATCTCGTCTGCGGCCTCCTGCTCGCCGAGAACATCTCCCACGGCCTCCTACTCAGGAAGGTACCAGTCCTGCAGTACCTGTACTACCTCGCCCAGATCTACATCGCGATGTCTCCGCTCAGCAACAACTCGCTGTTCCTCAACTACCACAGGAACCCGCTGCCGGAGTTCTTAGCTCGAGGGCTCTGCATCACTCTCAGTACTGACGACCCCCTGCAGTTTCACTTCACCAAGGAGCCGCTGATGGAAGAATACAGTATCGCAGCGCAAGTGTGGAAGCTCAGTTCATGCGACATGTGTGAATTGGCAAGGAATTCGGTGCTCATGTCCGGATTCCCGCACGAGATGAAGCAGTACTGGTTAGGGCCCAACTATACCAAGGAAGGTGTGGCCGGTAATGACATAACTCGAACCAACGTACCCGATATCCGCATTTCGTTCCGTCACGAGACCATCCTCGATGAGCTGACCAACATATTCAAGGATGGTATGTCTACTCAGAGATAA

Protein

MSIRGVQDGSRSPLIITDSFFDDGGSESPTSAVGAEAPRELPNELSAPYEVPQFPIEQIEKKLLIQRQLNVKAAECAQSVRSFAGSEAGAAAVFEEAARLRVPDDDDDEIILPHFQRVAISGEDTSGVPLEDLQQASSYLVQALEMRKRYMEMSQQSFSPITARFIRSMDADAVANHVPVKVPNKHIADHIVHPPFRDKDPWECPMPEPKGYSIRLNRGVFNMYRQGPNGEERLPYEYITLAQYIQDMNTMCNMIADGPLKSFCYRRLSYLSSKFQLHVLLNELRELASQKAVPHRDFYNIRKVDTHIHAASCMNQKHLLRFIKKTLKTHADEVVTLHKGTPMTLRSVFQSMNLSTYDLTVDMLDVHADRNTFHRFDKFNAKYNPIGESRLREVFLKTDNYMNGKYFARIIKEVASDLEESKYQNAELRLSVYGKSPGEWAKLAKWAIQYDVHSNNVRWLIQIPRLYDIFKSNKIMNDFHEFLNNIFQPLFEVTNDPNSNIELHKFLTHVIGFDSVDDESKPENPMLDTEVKSPEEWDDEENPPYAYYLYYMYANMTVLNHFRKEQGLNTFVLRPHCGEAGPVQHLVCGLLLAENISHGLLLRKVPVLQYLYYLAQIYIAMSPLSNNSLFLNYHRNPLPEFLARGLCITLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNSVLMSGFPHEMKQYWLGPNYTKEGVAGNDITRTNVPDIRISFRHETILDELTNIFKDGMSTQR

Catalytic Activity

AMP + H(+) + H2O = IMP + NH4(+)

Cofactor

Zn(2+)

Similarity

Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

Uniprot

H9IU76   A0A194PHC8   A0A2H1WEQ9   A0A2A4J7M0   A0A2A4J5Q4   A0A2A4J7N2   + More
A0A2W1BR58   A0A212EYI0   S4PD75   A0A026WZW8   F4W6E6   A0A195AW79   E2B347   A0A195FJD1   A0A151WZZ4   K7IR89   A0A195DMH5   E1ZV26   A0A1B6LRF2   A0A3L8DSI0   A0A1B6LF21   A0A1B6LWC6   A0A2J7QUJ3   A0A0A9WA91   A0A0A9W5I4   A0A1B6LD48   A0A0A9W2W7   A0A0K8TDN6   A0A1B6D3D1   A0A0P6IYH3   A0A1B6MLD3   A0A1I8M5T7   A0A034V694   A0A067RGI2   A0A182PQ60   A0A1B6KC71   A0A0K8TSL1   A0A1Q3G448   U5ESH6   A0A182IA57   A0A1B6DJ42   A0A182V244   H2KMF2   A0A034V8I5   A0A182XLP6   A0A1B6DMH7   A0A1L8DXU6   A0A034V9N6   A0A158P2M1   A0A2M3ZYQ5   F5HJE6   A0A182JES1   A0A1I8PX22   A0A182W4Q8   A0A2M3ZYP0   A0A182FJY9   W8BF48   A0A0K8VGA7   A0A1Q3G438   A0A182RV49   A0A1I8PX13   A0A182MF03   A0A182N109   A0A034V696   A0A1I8PX41   A0A1B6D8E0   T1PCR1   A0A1W4XN33   A0A034V9P0   A0A2J7QUI2   A0A2M4CXG1   A0A2M4CW16   A0A336MJR5   T1PNB5   T1DJB0   A0A2M4BEH8   A0A182Y7H3   A0A0A1X6W9   A0A1I8M5T6   A0A1I8M5T9   A0A336MIP2   A0A2M4BEW8   A0A1I8M5T5   W8B040   A0A0K8U8V6   A0A2M4BE94   A0A2M4BEB1   W5JP02   A0A2M3ZFZ9   A0A182QHY2   A0A0A1WZL6   A0A1Y1KFC9   A0A1Y1KCB1   A0A0L7QTV6   A0A1L8DXX6   A0A1A9WGD9   A0A1B6D983   A0A1A9XKL7   A0A1B6EGP5   A0A1L8DY01  

EC Number

3.5.4.6

Pubmed

19121390    26354079    28756777    22118469    23622113    24508170    + More
21719571    20798317    20075255    30249741    25401762    26823975    26999592    25315136    25348373    24845553    26369729    12364791    14747013    17210077    21347285    24495485    25244985    25830018    20920257    23761445    28004739   

EMBL

BABH01034219    BABH01034220    BABH01034221    KQ459604    KPI92114.1    ODYU01008185    + More
SOQ51570.1    NWSH01002867    PCG67412.1    PCG67415.1    PCG67413.1    KZ149945    PZC76811.1    AGBW02011505    OWR46545.1    GAIX01005062    JAA87498.1    KK107054    EZA61572.1    GL887707    EGI70281.1    KQ976731    KYM76219.1    GL445285    EFN89896.1    KQ981523    KYN40367.1    KQ982625    KYQ53483.1    KQ980724    KYN14036.1    GL434395    EFN74955.1    GEBQ01013760    JAT26217.1    QOIP01000004    RLU23286.1    GEBQ01017682    JAT22295.1    GEBQ01011984    JAT27993.1    NEVH01010578    PNF32244.1    GBHO01041839    GBHO01041837    JAG01765.1    JAG01767.1    GBHO01041842    GBHO01041841    GBRD01002545    JAG01762.1    JAG01763.1    JAG63276.1    GEBQ01018364    JAT21613.1    GBHO01041840    GBHO01041838    GBRD01002547    GDHC01012526    JAG01764.1    JAG01766.1    JAG63274.1    JAQ06103.1    GBRD01002546    JAG63275.1    GEDC01017104    JAS20194.1    GDUN01000039    JAN95880.1    GEBQ01003190    JAT36787.1    GAKP01020136    JAC38816.1    KK852478    KDR22976.1    GEBQ01030929    JAT09048.1    GDAI01000239    JAI17364.1    GFDL01000460    JAV34585.1    GANO01003241    JAB56630.1    APCN01001124    GEDC01011577    JAS25721.1    AAAB01008846    EAA45063.5    GAKP01020134    GAKP01020133    GAKP01020132    JAC38819.1    GEDC01010431    JAS26867.1    GFDF01002813    JAV11271.1    GAKP01020135    JAC38817.1    ADTU01006991    ADTU01006992    GGFK01000352    MBW33673.1    EGK96409.1    AXCP01007583    GGFK01000353    MBW33674.1    GAMC01014659    JAB91896.1    GDHF01014436    JAI37878.1    GFDL01000477    JAV34568.1    AXCM01001247    GAKP01020131    JAC38821.1    GEDC01015341    JAS21957.1    KA646562    AFP61191.1    GAKP01020130    JAC38822.1    PNF32245.1    GGFL01005380    MBW69558.1    GGFL01005355    MBW69533.1    UFQT01001348    SSX30145.1    KA649555    AFP64184.1    GAMD01001576    JAB00015.1    GGFJ01002303    MBW51444.1    GBXI01007228    GBXI01006890    JAD07064.1    JAD07402.1    SSX30146.1    GGFJ01002458    MBW51599.1    GAMC01014658    JAB91897.1    GDHF01029308    JAI23006.1    GGFJ01002235    MBW51376.1    GGFJ01002244    MBW51385.1    ADMH02000938    ETN64625.1    GGFM01006672    MBW27423.1    AXCN02001394    GBXI01010322    JAD03970.1    GEZM01088536    JAV58126.1    GEZM01088534    JAV58128.1    KQ414740    KOC62055.1    GFDF01002825    JAV11259.1    GEDC01015054    JAS22244.1    GEDC01000238    JAS37060.1    GFDF01002812    JAV11272.1   

Proteomes

UP000005204    UP000053268    UP000218220    UP000007151    UP000053097    UP000007755    + More
UP000078540    UP000008237    UP000078541    UP000075809    UP000002358    UP000078492    UP000000311    UP000279307    UP000235965    UP000095301    UP000027135    UP000075885    UP000075840    UP000075903    UP000007062    UP000076407    UP000005205    UP000075880    UP000095300    UP000075920    UP000069272    UP000075900    UP000075883    UP000075884    UP000192223    UP000076408    UP000000673    UP000075886    UP000053825    UP000091820    UP000092443   

PRIDE

H9IU76   

Pfam

PF00962   A_deaminase

Interpro

IPR032466   Metal_Hydrolase        + More
IPR001365   A/AMP_deaminase_dom       
IPR006329   AMPD       
IPR006650   A/AMP_deam_AS       
IPR029749   AMPD2       

SUPFAM

SSF51556   SSF51556       

CDD

cd01319  AMPD

ProteinModelPortal

H9IU76   A0A194PHC8   A0A2H1WEQ9   A0A2A4J7M0   A0A2A4J5Q4   A0A2A4J7N2   + More
A0A2W1BR58   A0A212EYI0   S4PD75   A0A026WZW8   F4W6E6   A0A195AW79   E2B347   A0A195FJD1   A0A151WZZ4   K7IR89   A0A195DMH5   E1ZV26   A0A1B6LRF2   A0A3L8DSI0   A0A1B6LF21   A0A1B6LWC6   A0A2J7QUJ3   A0A0A9WA91   A0A0A9W5I4   A0A1B6LD48   A0A0A9W2W7   A0A0K8TDN6   A0A1B6D3D1   A0A0P6IYH3   A0A1B6MLD3   A0A1I8M5T7   A0A034V694   A0A067RGI2   A0A182PQ60   A0A1B6KC71   A0A0K8TSL1   A0A1Q3G448   U5ESH6   A0A182IA57   A0A1B6DJ42   A0A182V244   H2KMF2   A0A034V8I5   A0A182XLP6   A0A1B6DMH7   A0A1L8DXU6   A0A034V9N6   A0A158P2M1   A0A2M3ZYQ5   F5HJE6   A0A182JES1   A0A1I8PX22   A0A182W4Q8   A0A2M3ZYP0   A0A182FJY9   W8BF48   A0A0K8VGA7   A0A1Q3G438   A0A182RV49   A0A1I8PX13   A0A182MF03   A0A182N109   A0A034V696   A0A1I8PX41   A0A1B6D8E0   T1PCR1   A0A1W4XN33   A0A034V9P0   A0A2J7QUI2   A0A2M4CXG1   A0A2M4CW16   A0A336MJR5   T1PNB5   T1DJB0   A0A2M4BEH8   A0A182Y7H3   A0A0A1X6W9   A0A1I8M5T6   A0A1I8M5T9   A0A336MIP2   A0A2M4BEW8   A0A1I8M5T5   W8B040   A0A0K8U8V6   A0A2M4BE94   A0A2M4BEB1   W5JP02   A0A2M3ZFZ9   A0A182QHY2   A0A0A1WZL6   A0A1Y1KFC9   A0A1Y1KCB1   A0A0L7QTV6   A0A1L8DXX6   A0A1A9WGD9   A0A1B6D983   A0A1A9XKL7   A0A1B6EGP5   A0A1L8DY01  

PDB

2A3L     E-value=2.1306e-160,     Score=1454

KEGG

101746046    K01490 AMP deaminase [EC:3.5.4.6] | (RefSeq) AMP deaminase 2

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0003876   GO:0032264   GO:0046872   GO:0046033   GO:0005829   GO:0006188   GO:0019239   GO:0006886   GO:0016192   GO:0030117   GO:0007154   GO:0016020   GO:0005112   GO:0015930  

PANTHER

PTHR11359   PTHR11359:SF3  

Length:

752

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.763419999999999

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00018

outside

1  -  752

 

 

Pi

239.543872

Theta

178.515514

Tajima's D

1.480591

CLR

0.261915

CSRT

0.782960851957402

Interpretation

Uncertain