Gene

KWMTBOMO14932

Pre Gene Modal

BGIBMGA000768

Annotation

putative_phospholipase_B-like_2_precursor_[Danaus_plexippus]

Location

Bomo_Chr25(-):675457-687672      View in EpiBrowser

Full name

Phospholipase B-like       + More
Putative phospholipase B-like 2      

Alternative Name

76 kDa protein
LAMA-like protein 2
Lamina ancestor homolog 2
Phospholipase B domain-containing protein 2

Location in the cell

Lysosomal   Reliability : 1.863 PlasmaMembrane   Reliability : 1.226

CDS

ATGTTGATTAGTTTAATATTTTTTAGTTTATTTTATGCTTGTAAATGTGAATATGGGTTTGTTTTGTGGTCTGAAAATAAACCTACTGTAACCGTGACTGACTATTACGCTGATATACCCGATGTATACGTAGCGAAAGCAACTTACACCAACGAAATAAATAATACAGGTTGGGCATTTCTTGAGCTGCACACATCAAGAGACTCAACAGACGAGAAACAAGCTTATTCAGCTGGTTTTCTGGAAGGATTCCTCACAAGAGATCTGATATGGATGCATTGGCAAAATGTTCTGAAAGGATATTGCTTTAACAAAACTGATGTATGCGCACTAATTGAAGATTATTTAGATAAAAATGAAGATTACATAGCATCTATGGTGCAAGAACACTACGAGGATCCTTATTGGTACCAGATAAAGCTATACTACATCCAGCTGGAAGGCCTAGCAGCCGGCTACAATGATGCCACTAAGAGCATGTACGAGTGGCTCACTGTAAGAGATATACTTTGGATTAACATGCTGGGTGACTTGGACGACCTGGCGTTCGCGCTGTCCATGCCAAGGGAGACGCCCGAGGGCCTGATGTTCGGGGAGCACTGCTCGGGGCTGGTGAAGCTGCTGCCGGACCTCTCGGACCTGTACACGGCGCAGGTCACGTGGAACAGCTACCAGTCGATGCTACGGATCCAAAAGATGTACGTGATGAACTACATGACGTCACCGGGCAGCGGGGTCCTCATACCCGGCAGGAAAATGTCGCTCTCCTCCTACCCGGCCTTCGTACAGTCGACGGACGACTTCTACGTGATGTCGTCGGGGCTGGTGGCCGCCGAGACCACCATCGGCAACAGCAACCGGACGCTGTACGAGCACGTGCGGCCAGAGGGACAGATATTGGAGTTCGTTCGCGCCATGGTCGCCAACCGGCTGGCCACGGACGGCGCGCGCTGGGTCCGCCTGTTCAGGGACCACAACAGCGGCACCTATAACAACCAGTGGTACGTTGTAGATTACAACAAGTTCACGCCGGCTGTTGGGAAGATGAAGGGGTCTGTGAGGCCGGGCCTGCTGTGGGTGGTTGAGCAGCTACCGGGATACACAGAGGCGGCCGATATAACTGAAGAGCTCAAGCAAACTTCGTATTTCCCATCCTACAACATCGCGTACTTCCCGAGCGTCTTCAACTTGAGCGGAGGGAACGAGCGAGTGAACACTTACGGCGACTGGTTCGGCTACCACACCAACCCCAGGGCGAAGATATTCAAGCAGAAACAGAGTGAGATCCACAATCTGCGCGACATGTACCGGACGATGCGGTACAACGACTACCGGCACGACCCGCTGTCGCGCTGCGCCCCCTGCGCGCCCCCCTACAGCGCCGCCAACGCAGTCGCCGCCAGGAACGACCTCAACCCCGCCAACGGTACGTACCCGTTCAGAGCCTTAGGACATCGCAGTCACGGAGCCACCGACGCGAAGATCACGAGCTCGCTGCTCAGGAAGACTTACCAGTTCATAGCCGTGTCGAGCCCCACCTACAACTTGTCCAGGGGGGTGCCGCCCTTCGTTTGGAGTAAGTTCGACATGGGTCCGCAGATATCTCACGTGGGCCACCCCGATGTGTGGATGTTCCCACCCTTGCTCCACCGCTGGGAGTGGGGATAG

Protein

MLISLIFFSLFYACKCEYGFVLWSENKPTVTVTDYYADIPDVYVAKATYTNEINNTGWAFLELHTSRDSTDEKQAYSAGFLEGFLTRDLIWMHWQNVLKGYCFNKTDVCALIEDYLDKNEDYIASMVQEHYEDPYWYQIKLYYIQLEGLAAGYNDATKSMYEWLTVRDILWINMLGDLDDLAFALSMPRETPEGLMFGEHCSGLVKLLPDLSDLYTAQVTWNSYQSMLRIQKMYVMNYMTSPGSGVLIPGRKMSLSSYPAFVQSTDDFYVMSSGLVAAETTIGNSNRTLYEHVRPEGQILEFVRAMVANRLATDGARWVRLFRDHNSGTYNNQWYVVDYNKFTPAVGKMKGSVRPGLLWVVEQLPGYTEAADITEELKQTSYFPSYNIAYFPSVFNLSGGNERVNTYGDWFGYHTNPRAKIFKQKQSEIHNLRDMYRTMRYNDYRHDPLSRCAPCAPPYSAANAVAARNDLNPANGTYPFRALGHRSHGATDAKITSSLLRKTYQFIAVSSPTYNLSRGVPPFVWSKFDMGPQISHVGHPDVWMFPPLLHRWEWG

Description

Putative phospholipase.

Subunit

Interacts with IGF2R.

Similarity

Belongs to the phospholipase B-like family.

Keywords

Alternative splicing   Complete proteome   Direct protein sequencing   Disulfide bond   Glycoprotein   Hydrolase   Lipid degradation   Lipid metabolism   Lysosome   Polymorphism   Reference proteome   Signal  

Feature

chain  Phospholipase B-like
splice variant  In isoform 2.
sequence variant  In dbSNP:rs7965471.

Uniprot

A0A212EHB7   A0A3S2NYN4   A0A2H1WMA6   A0A1E1VY59   A0A2W1BVI5   A0A194PHD8   + More
A0A2J7PU65   J9K224   A0A2I9LPG8   A0A2H8TJI2   A0A0P5J9R6   A0A164ZX29   A0A0N8BAQ7   A0A0P6EVS2   A0A0N8B5Q0   A0A0P6GG78   A0A0P5AKM6   A0A0P5UML3   A0A0P5GTM8   A0A0N8DYW5   A0A0P5RGR3   A0A067RJD1   A0A0P5BN34   A0A0P6DC37   A0A0P5HHQ7   A0A0P6AAA5   A0A0P5QS33   A0A0P5FWY2   A0A0P6IZ23   A0A0P5IGE3   A0A0P5HKV5   A0A0P5K8J4   A0A0P5MCI9   E9GSQ2   A0A0N8E886   A0A0P5MSK5   A0A0K2SZE0   A0A0P5QAW2   A0A0P5QP37   A0A0P6FKH2   A0A1W7R9X8   R7VB97   A0A3R7PL47   A0A0P5NEB0   A0A1S3H1M5   A0A0P5JS83   A0A2P8YQZ5   T1IJU9   A0A1S3H3H8   A0A0P6ECV0   A0A0P6IGS1   A0A0P5Q498   A0A2R8QFI9   A0A0P5ZP95   A0A0P5G2M1   A0A0P5H812   A2RV19   A0A293M231   A0A3B3HSJ2   A0A0P6FAS0   V9KJN6   A0A3P9KUP8   A0A0S7G278   A0A3P9H0U9   A0A210QBW5   V9KKP6   H2LVN2   A0A3B1IZJ5   W5U8Z2   M3ZZL5   A0A0P4VWC0   V9KIX4   A0A3B4EI41   J9JWY7   V5H983   A0A034WWT4   A0A1V9XR98   A0A151N4M2   A0A060WGU2   G7PIR3   T1FMY2   G7N5Q2   A0A224YPI2   A0A2K5E2G1   A0A315V885   A0A2K6S5I6   A0A0P5PVF2   A0A2I2UDS4   F7I3N3   A0A0P5DKU7   A0A2K5YWZ4   Q8NHP8   A0A2K6DCS4   A0A2K5WZV8   I2CYI6   A0A131YKS0   U3ECB3   H9YUP8   H9F441  

EC Number

3.1.1.-

Pubmed

22118469    28756777    26354079    29248469    24845553    21292972    + More
23254933    29403074    23594743    17554307    24402279    28812685    25329095    23127152    23542700    25765539    24762651    28327890    22293439    24755649    22002653    28797301    29703783    17975172    16541075    15489334    17105447    19159218    21269460    25944712    25319552    26830274    25243066   

EMBL

AGBW02014918    OWR40876.1    RSAL01000022    RVE52351.1    ODYU01009603    SOQ54147.1    + More
GDQN01011388    JAT79666.1    KZ149945    PZC76800.1    KQ459604    KPI92124.1    NEVH01021208    PNF19877.1    ABLF02016253    ABLF02016254    GFWZ01000288    MBW20278.1    GFXV01002394    MBW14199.1    GDIQ01209012    GDIQ01209011    JAK42713.1    LRGB01000687    KZS16891.1    GDIQ01269525    GDIQ01219257    GDIQ01196203    JAK55522.1    GDIQ01064566    JAN30171.1    GDIQ01210259    JAK41466.1    GDIQ01044063    JAN50674.1    GDIP01197995    JAJ25407.1    GDIP01110890    JAL92824.1    GDIQ01235749    GDIQ01052179    JAK15976.1    GDIQ01078348    JAN16389.1    GDIQ01110335    JAL41391.1    KK852473    KDR23108.1    GDIP01183079    JAJ40323.1    GDIQ01080247    JAN14490.1    GDIQ01233292    GDIQ01125487    JAK18433.1    GDIP01032596    JAM71119.1    GDIQ01110336    JAL41390.1    GDIQ01254598    JAJ97126.1    GDIQ01025520    JAN69217.1    GDIQ01213750    JAK37975.1    GDIQ01231640    JAK20085.1    GDIQ01213749    JAK37976.1    GDIQ01157624    JAK94101.1    GL732562    EFX77541.1    GDIQ01052180    JAN42557.1    GDIQ01152521    JAK99204.1    HACA01001793    CDW19154.1    GDIQ01138384    JAL13342.1    GDIQ01112086    JAL39640.1    GDIQ01063061    JAN31676.1    GFAH01000439    JAV47950.1    AMQN01004460    KB293569    ELU15812.1    QCYY01001783    ROT75354.1    GDIQ01146629    JAL05097.1    GDIQ01200518    JAK51207.1    PYGN01000420    PSN46677.1    JH430359    GDIQ01064567    JAN30170.1    GDIQ01031225    JAN63512.1    GDIQ01140533    JAL11193.1    CABZ01067558    GDIP01040606    JAM63109.1    GDIQ01247434    JAK04291.1    GDIQ01236806    JAK14919.1    BC133139    AAI33140.1    GFWV01010304    MAA35033.1    GDIQ01063062    JAN31675.1    JW865809    AFO98326.1    GBYX01477768    GBYX01458196    GBYX01458194    JAO23359.1    NEDP02004233    OWF46224.1    JW865989    AFO98506.1    JT407599    AHH38044.1    GDRN01103450    JAI58085.1    JW865413    AFO97930.1    ABLF02016250    GANP01013261    JAB71207.1    GBBO01000014    JAC59114.1    MNPL01005424    OQR76026.1    AKHW03004053    KYO31774.1    FR904540    CDQ66372.1    CM001286    EHH66740.1    AMQM01004014    KB096411    ESO04980.1    CM001263    EHH21209.1    GFPF01004594    MAA15740.1    NHOQ01002094    PWA19550.1    GDIQ01129778    JAL21948.1    AANG04002472    GDIP01154796    JAJ68606.1    AC010178    BC030618    BC071832    AQIA01012788    JV667358    AFJ72021.1    GEDV01009455    JAP79102.1    GAMT01002761    GAMS01005770    GAMR01002847    GAMQ01003538    GAMP01010553    JAB09100.1    JAB17366.1    JAB31085.1    JAB38313.1    JAB42202.1    JU470610    AFH27414.1    JU325644    AFE69400.1   

Proteomes

UP000007151    UP000283053    UP000053268    UP000235965    UP000007819    UP000076858    + More
UP000027135    UP000000305    UP000014760    UP000283509    UP000085678    UP000245037    UP000000437    UP000001038    UP000265180    UP000265200    UP000242188    UP000018467    UP000221080    UP000002852    UP000261440    UP000192247    UP000050525    UP000193380    UP000009130    UP000015101    UP000233020    UP000233220    UP000011712    UP000008225    UP000233140    UP000005640    UP000233120    UP000233100   

PRIDE

Q8NHP8   

Pfam

PF04916   Phospholip_B

Interpro

IPR007000   PLipase_B-like       

ProteinModelPortal

A0A212EHB7   A0A3S2NYN4   A0A2H1WMA6   A0A1E1VY59   A0A2W1BVI5   A0A194PHD8   + More
A0A2J7PU65   J9K224   A0A2I9LPG8   A0A2H8TJI2   A0A0P5J9R6   A0A164ZX29   A0A0N8BAQ7   A0A0P6EVS2   A0A0N8B5Q0   A0A0P6GG78   A0A0P5AKM6   A0A0P5UML3   A0A0P5GTM8   A0A0N8DYW5   A0A0P5RGR3   A0A067RJD1   A0A0P5BN34   A0A0P6DC37   A0A0P5HHQ7   A0A0P6AAA5   A0A0P5QS33   A0A0P5FWY2   A0A0P6IZ23   A0A0P5IGE3   A0A0P5HKV5   A0A0P5K8J4   A0A0P5MCI9   E9GSQ2   A0A0N8E886   A0A0P5MSK5   A0A0K2SZE0   A0A0P5QAW2   A0A0P5QP37   A0A0P6FKH2   A0A1W7R9X8   R7VB97   A0A3R7PL47   A0A0P5NEB0   A0A1S3H1M5   A0A0P5JS83   A0A2P8YQZ5   T1IJU9   A0A1S3H3H8   A0A0P6ECV0   A0A0P6IGS1   A0A0P5Q498   A0A2R8QFI9   A0A0P5ZP95   A0A0P5G2M1   A0A0P5H812   A2RV19   A0A293M231   A0A3B3HSJ2   A0A0P6FAS0   V9KJN6   A0A3P9KUP8   A0A0S7G278   A0A3P9H0U9   A0A210QBW5   V9KKP6   H2LVN2   A0A3B1IZJ5   W5U8Z2   M3ZZL5   A0A0P4VWC0   V9KIX4   A0A3B4EI41   J9JWY7   V5H983   A0A034WWT4   A0A1V9XR98   A0A151N4M2   A0A060WGU2   G7PIR3   T1FMY2   G7N5Q2   A0A224YPI2   A0A2K5E2G1   A0A315V885   A0A2K6S5I6   A0A0P5PVF2   A0A2I2UDS4   F7I3N3   A0A0P5DKU7   A0A2K5YWZ4   Q8NHP8   A0A2K6DCS4   A0A2K5WZV8   I2CYI6   A0A131YKS0   U3ECB3   H9YUP8   H9F441  

PDB

3FGW     E-value=1.95265e-116,     Score=1074

KEGG

101745130    no KO assigned | (RefSeq) putative phospholipase B-like 2

GO

GO:0016787   GO:0016042   GO:0005764   GO:0070062   GO:0043202   GO:0004620  

PANTHER

PTHR12370  

Subcellular location

Lysosome lumen  

SignalP

Position:   1 - 16,         Likelihood:  0.950149

 

 

Length:

555

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.13675

Exp number, first 60 AAs:

0.13154

Total prob of N-in:

0.00618

outside

1  -  555

 

 

Pi

252.748367

Theta

169.678585

Tajima's D

1.598757

CLR

0.059159

CSRT

0.808459577021149

Interpretation

Uncertain