SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO14928
Pre Gene Modal
BGIBMGA000770
Annotation
PREDICTED:_putative_tyrosine-protein_kinase_Wsck_[Amyelois_transitella]
Full name
Putative tyrosine-protein kinase Wsck      
Location in the cell
PlasmaMembrane   Reliability : 2.998
 

Sequence

CDS
ATGGTTATGATTAGAAATTGCTGCCTGGAAACAATGGAGAAGTGGTTTCAGAGAATATTTGTGATCATATTGTTGTGTTTTGCTGCATGTTTATGTGAACGTGGAGATTACATTGGCTGCTATGTGCTAAAAGCCGAAGAAGTATTAAATACGCACACGGGTCAATCCGTGGACGCATGTCTCAATGCTTGTGAACAGGTACATTACAAATATGCTTTAATAGGCAATGAATCTACTTGTTTCTGCGGCAATTCACCGGGAAAGTTCAAACTGCCCTTAGACTCCTGTCACACGGTATGCCCTAAGAACGAAACTCAAAAATGCGGCGGTAACAATGCTACTAGTGTATATGATACGGATGTGGTCGCTCCAGGTCAGCCAAGCAATCTGGTCCTATTTAACGCCACAGAGACTACAGTGAGACTGCGTTGGTCTGCTCCTAATGCATACTCCTTCATAACTTCATATGTGATTCGAGCAGCTGTTATTGAAACTTATTCTGATTACAATCTGAAACCATTGGAATGGAGAGTATCCAATGAAACTTTAAATATGGAACTCTTAAACCTGCATCCTGGGTCCAAGTACAACATCAGTGTTGCAGCCTTGAATTATGATGAAGAAGGTCCAAATATTACCATGGTTACTGAGACAGTAATTGGAACACCAGACCCTAGTCCACCTGATGTAGAGATAATTCAAAGACGAGGTGACAGAATGGTTGTACATATTCCCAAAGCTAAGAATGTGAATGGGCCAGTTTCTATGTACAGAATAGTCATTTCTATAGAGTTGTATCAACAAGGCTTCATAGTGGATACTCTCAGTAACCATACATATGCAACTGAACAAGGTCTACCTTACTACATCACTGCTGAATTGGATCCTGATGATATAAAGACTGATTTCATCATTGGAGACAGGAGTACATACAATGGTTTCTACAATGCTCCATTGCCATTAACTAATGACATTGATGTGTCTTTAGGAGTAGTGAGTGAGAAGAACCATGTCAGAAAAGTTAGATATGCTGAGTCAACCAAAAAGATTATTTTGAACATTAATGAACCTGAGGAAGTATCTCCGATGGTAGTAGCACTAGGTGCTGGTATTGCCATTGGAGTAGTACTACTGCTGATTGGCATAGGACTGATTATAATTTTACGTCGCAGAATACAGTTTGTACGAATGCAAAGGGGATCTCAATCAATGCCGTTAAGTTTAAGTGAACCTTGTGTTGAAATAGAAAACTCCGGATTTATTCTTGAGGATGAAGAAAGAGTAGACTACTATGGAAATTTAAAACGTAAACTTTGGAATATTCCACGGAATTTAATTGAAACAGACATATCATGTGTTGTTGGTGTTGGGACATATGGTAAATTCACTAAAGGAAAAGTGCAACAAGGTGGAGTGCAGACTGTTGGCTTGGTTCAGGTCATAGCTGATAGAGAACTTGAAAAAACAGAGAAGAAGCAGATGCTACAAGAATTAGATCTGTTGATAAAAACCAGTGAACATGAAAATGTTATCTCATTAATAGGCATCTGTGAGACTAATACCACTTTGCTTGTAGTTTTGGAAGACATTAAGAAAACTTTGAAAGAGATGTTGCTGTTAAGTAGACAAAGGGACATTCAGAATAATAAATTTTGCTCGATAACAGAGAATAAGGTATTACAGATTTGTGTGCAAGTTGCCCGAGGAATGGAGTATCTTCACACAAGGAAAATTGTCCATAAGAAACTTTGTTGCAGAAACATGATCATAAGTGAAAATGGAACTGTCAAAATAGCTGGTTTTGGCTTGTCACACTTAAGATCTTTACATGAGACTCCTGATTATACAAGATGGACTTCTCATGAAATGTTAAGACAAACTAGATATAATCCAAAGGCAGATGTTTGGTCTTTTGGAGTTTTGATGTGGGAAGTCCTTACCCTGGGAGCAACTCCATATTCTCATTCAGGGAATAAAGATGTAGGCAGTAGGATATTAAGAGGAATGAGGCCCTCACAGCCTTCGTATGTTGGAGATGAGTTGTTCCAAGTGTGTCTTCAGTGCTGGCAGGTTGATCCCGATGAGAGACCCACCTTCTCATCTCTAGTTATTGAACTGACACCTTTTTCTGAAGCTCCAGGGACTAGGAATTTAAGCTTTACTCATTATAACGGTTTTGAGTTTGAACCACATATTCCCCAGTATGAAGTTATTTCTTAA
Protein
MVMIRNCCLETMEKWFQRIFVIILLCFAACLCERGDYIGCYVLKAEEVLNTHTGQSVDACLNACEQVHYKYALIGNESTCFCGNSPGKFKLPLDSCHTVCPKNETQKCGGNNATSVYDTDVVAPGQPSNLVLFNATETTVRLRWSAPNAYSFITSYVIRAAVIETYSDYNLKPLEWRVSNETLNMELLNLHPGSKYNISVAALNYDEEGPNITMVTETVIGTPDPSPPDVEIIQRRGDRMVVHIPKAKNVNGPVSMYRIVISIELYQQGFIVDTLSNHTYATEQGLPYYITAELDPDDIKTDFIIGDRSTYNGFYNAPLPLTNDIDVSLGVVSEKNHVRKVRYAESTKKIILNINEPEEVSPMVVALGAGIAIGVVLLLIGIGLIIILRRRIQFVRMQRGSQSMPLSLSEPCVEIENSGFILEDEERVDYYGNLKRKLWNIPRNLIETDISCVVGVGTYGKFTKGKVQQGGVQTVGLVQVIADRELEKTEKKQMLQELDLLIKTSEHENVISLIGICETNTTLLVVLEDIKKTLKEMLLLSRQRDIQNNKFCSITENKVLQICVQVARGMEYLHTRKIVHKKLCCRNMIISENGTVKIAGFGLSHLRSLHETPDYTRWTSHEMLRQTRYNPKADVWSFGVLMWEVLTLGATPYSHSGNKDVGSRILRGMRPSQPSYVGDELFQVCLQCWQVDPDERPTFSSLVIELTPFSEAPGTRNLSFTHYNGFEFEPHIPQYEVIS

Summary

Catalytic Activity
ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]
Similarity
Belongs to the protein kinase superfamily. Tyr protein kinase family.
Keywords
ATP-binding   Complete proteome   Glycoprotein   Kinase   Membrane   Nucleotide-binding   Receptor   Reference proteome   Signal   Transferase   Transmembrane   Transmembrane helix   Tyrosine-protein kinase  
Feature
chain  Putative tyrosine-protein kinase Wsck
EC Number
2.7.10.1
EMBL
BABH01034195    NWSH01002830    PCG67469.1    ODYU01009119    SOQ53317.1    JTDY01001252    + More
KOB74400.1    KZ149945    PZC76796.1    KQ460205    KPJ17052.1    KQ459604    KPI92128.1    KQ971342    EFA04011.1    KK852812    KDR15852.1    GEZM01087442    GEZM01087441    JAV58686.1    GEZM01087440    JAV58688.1    NEVH01019068    PNF23084.1    APGK01020340    KB740193    KB631669    ENN81097.1    ERL85211.1    GFDF01007158    JAV06926.1    GFDF01007453    JAV06631.1    JXUM01124147    JXUM01124148    JXUM01124149    KQ566797    KXJ69817.1    GECZ01031770    JAS37999.1    CH478474    EAT32920.1    ADMH02000528    ETN66101.1    DS232440    EDS41757.1    QCYY01000299    ROT85360.1    GGFJ01002547    MBW51688.1    GGFJ01002436    MBW51577.1    GDRN01079280    GDRN01079278    JAI62429.1    GGFJ01002437    MBW51578.1    GGFM01004061    MBW24812.1    JH431313    UFQT01000063    SSX19278.1    AJWK01001848    GDRN01079279    JAI62428.1    AXCN02000558    AXCM01014945    ATLV01023268    KE525341    KFB48796.1    KK114040    KFM61587.1    AAAB01008807    EAA04674.4    GGFK01009153    MBW42474.1    APCN01003696    KQ977394    KYN03009.1    NNAY01002687    OXU20774.1    KQ435794    KOX73969.1    KQ414591    KOC70294.1    KQ976440    KYM86577.1    PYGN01000058    PSN55853.1    KQ982557    KYQ55085.1    GL888624    EGI58811.1    GGFK01009286    MBW42607.1    KQ981856    KYN34569.1    CH477789    EAT36188.1    CCAG010007921    OUUW01000005    SPP81305.1    GGFK01009189    MBW42510.1    GL438602    EFN68707.1    KQ979955    KYN18543.1    KQ797310    OAD46971.1    KK107929    EZA47110.1    QOIP01000003    RLU24613.1    ADTU01005183    GDHF01011932    JAI40382.1    LBMM01010833    KMQ87201.1    KQ434879    KZC09944.1    CM000070    EAL26860.2    GAKP01012771    JAC46181.1    CM000364    EDX14249.1    GBXI01005860    JAD08432.1    AE014297    AY058568    BT001869    CM000160    EDW98918.1    CH954182    EDV53833.1    CH480815    EDW43520.1    GAMC01021246    JAB85309.1    KA645007    AFP59636.1    JXJN01013186    CH902617    EDV42008.1    ABJB010493805    ABJB010881114    ABJB010919592    ABJB010979276    DS636620    EEC01562.1    CH940650    EDW66531.1    CVRI01000040    CRK94778.1    JQ611724    AFK29238.1    GBYB01009333    JAG79100.1    GL446901    EFN87102.1    CH933806    EDW13975.1   
Pfam
PF00041   fn3        + More
PF07714   Pkinase_Tyr
PF01822   WSC
PF18861   PTP_tm
PF04922   DIE2_ALG10
PF13359   DDE_Tnp_4
PF03564   DUF1759
Interpro
IPR011009   Kinase-like_dom_sf        + More
IPR036116   FN3_sf       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR003961   FN3_dom       
IPR013783   Ig-like_fold       
IPR000719   Prot_kinase_dom       
IPR002889   WSC_carb-bd       
IPR041201   PTPRJ_TM       
IPR016900   Alg10       
IPR027806   HARBI1_dom       
IPR005312   DUF1759       
SUPFAM
SSF56112   SSF56112        + More
SSF49265   SSF49265       
Gene 3D
PDB
3EFL     E-value=1.90949e-35,     Score=376

Ontologies

Topology

Subcellular location
Membrane  
SignalP
Position:   1 - 32,         Likelihood:  0.795420
 
 
Length:
739
Number of predicted TMHs:
2
Exp number of AAs in TMHs:
41.9297300000001
Exp number, first 60 AAs:
12.8973
Total prob of N-in:
0.31302
POSSIBLE N-term signal
sequence
outside
1  -  14
TMhelix
15  -  32
inside
33  -  364
TMhelix
365  -  387
outside
388  -  739
 
 

Population Genetic Test Statistics

Pi
244.360142
Theta
193.810968
Tajima's D
0.736338
CLR
0.096979
CSRT
0.590220488975551
Interpretation
Uncertain
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